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1. 发明申请

US20070255398A1 TWO-PART EXPANDABLE HEART VALVE 有权
标题翻译：两部分可膨胀心脏瓣膜
公开(公告)号：US20070255398A1
公开(公告)日：2007-11-01
申请号：US11749722
申请日：2007-05-16
申请人： Jibin Yang , Matthew Pease , Brandon Walsh
发明人： Jibin Yang , Matthew Pease , Brandon Walsh
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2/848 , A61F2/91 , A61F2/92 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2250/006 , Y10S623/90
摘要： Expandable heart valves for minimally invasive valve replacement surgeries are disclosed. The valves are rolled into a first, contracted configuration for minimally invasive delivery and then unrolled or unfurled at the implantation site. One- and two-piece stents may be used in conjunction with a plurality of flexible leaflet-forming membranes. The one-piece stents may include an annulus anchoring section, a sinus section with the membranes attached over sinus apertures, and a rigid outflow section. The two-piece stent may include a primary stent to provide a tubular base at the annulus, and a secondary stent having the membranes that couples within the primary stent. Lockout tabs to secure the stents in their expanded shapes are provided. Also, alignment structure may be provided to ensure concentric unfurling. Anchoring barbs at the stent edges or in the stent body secure the valve within the annulus. Methods of implantation are also provided.
摘要翻译：公开了用于微创瓣膜置换手术的可扩张心脏瓣膜。这些阀门被卷入第一个收缩构造，用于微创输送，然后在植入部位展开或展开。单件和两件式支架可与多个柔性成叶膜结合使用。一体式支架可以包括环形锚固部分，具有附着在窦口上的膜的窦部分和刚性流出部分。两件式支架可以包括在环形空间处提供管状基部的主支架，以及具有在主支架内连接的膜的辅助支架。提供锁定标签以将支架固定在其扩展形状中。此外，可以提供对准结构以确保同心展开。在支架边缘或支架主体中锚定倒钩固定瓣膜内的瓣膜。还提供了植入方法。

2. 发明申请

US20060173537A1 Rolled minimally invasive heart valves 有权
标题翻译：滚动微创心脏瓣膜
公开(公告)号：US20060173537A1
公开(公告)日：2006-08-03
申请号：US10653843
申请日：2003-09-02
申请人： Jibin Yang , Matthew Pease , Brandon Walsh
发明人： Jibin Yang , Matthew Pease , Brandon Walsh
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2/848 , A61F2/91 , A61F2/92 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2250/006 , Y10S623/90
摘要： Expandable heart valves for minimally invasive valve replacement surgeries are disclosed. The valves are rolled into a first, contracted configuration for minimally invasive delivery and then unrolled or unfurled at the implantation site. One- and two-piece stents may be used in conjunction with a plurality of flexible leaflet-forming membranes. The one-piece stents may include an annulus anchoring section, a sinus section with the membranes attached over sinus apertures, and a rigid outflow section. The two-piece stent may include a primary stent to provide a tubular base at the annulus, and a secondary stent having the membranes that couples within the primary stent. Lockout tabs to secure the stents in their expanded shapes are provided. Also, alignment structure may be provided to ensure concentric unfurling. Anchoring barbs at the stent edges or in the stent body secure the valve within the annulus. Methods of implantation are also provided.
摘要翻译：公开了用于微创瓣膜置换手术的可扩张心脏瓣膜。这些阀门被卷入第一个收缩构造，用于微创输送，然后在植入部位展开或展开。单件和两件式支架可与多个柔性成叶膜结合使用。一体式支架可以包括环形锚固部分，具有附着在窦口上的膜的窦部分和刚性流出部分。两件式支架可以包括在环形空间处提供管状基部的主支架，以及具有在主支架内连接的膜的辅助支架。提供锁定标签以将支架固定在其扩展形状中。此外，可以提供对准结构以确保同心展开。在支架边缘或支架主体中锚定倒钩固定瓣膜内的瓣膜。还提供了植入方法。

3. 发明授权

US08551132B2 Methods and systems for endovascularly clipping and repairing lumen and tissue defects 有权
标题翻译：血管内夹闭和修复管腔和组织缺陷的方法和系统
公开(公告)号：US08551132B2
公开(公告)日：2013-10-08
申请号：US11737700
申请日：2007-04-19
申请人： Joseph Eskridge , Gilbert Clarke , Matthew Pease , Gregory Martin Mast , John Conrad Muskivitch
发明人： Joseph Eskridge , Gilbert Clarke , Matthew Pease , Gregory Martin Mast , John Conrad Muskivitch
IPC分类号： A61M29/00
CPC分类号： A61B17/122 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12172 , A61B90/39 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61F2/06
摘要： An implantable closure structure is delivered using minimally invasive techniques, and inhibits the migration of liquid and particulate matter from inside a physiological cavity or opening, such as an aneurysm or a septal defect, as well as inhibiting the flow of liquid and particulate matter, such as from an associated blood vessel or chamber, into the physiological cavity or opening. The device has a closure structure that covers the neck or opening of a cavity and has one or more anchoring structures for supporting and retaining the closure structure in place across the cavity or opening.
摘要翻译：使用微创技术递送可植入闭合结构，并且抑制液体和颗粒物质从生理空腔或开口内的移动，例如动脉瘤或间隔缺损，以及抑制液体和颗粒物质的流动，例如从相关的血管或腔室进入生理腔或开口。该装置具有覆盖空腔的颈部或开口的封闭结构，并且具有一个或多个锚固结构，用于将闭合结构支撑并保持在空腔或开口上的适当位置。

4. 发明申请

US20070191884A1 METHODS AND SYSTEMS FOR ENDOVASCULARLY CLIPPING AND REPAIRING LUMEN AND TISSUE DEFECTS 有权
标题翻译：用于血管内切除和修复的组织和组织缺陷的方法和系统
公开(公告)号：US20070191884A1
公开(公告)日：2007-08-16
申请号：US11737700
申请日：2007-04-19
申请人： Joseph Eskridge , Gilbert Clarke , Matthew Pease , Gregory Mast , John Muskivitch
发明人： Joseph Eskridge , Gilbert Clarke , Matthew Pease , Gregory Mast , John Muskivitch
IPC分类号： A61B17/08
CPC分类号： A61B17/122 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12172 , A61B90/39 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61F2/06
摘要： An implantable closure structure is delivered using minimally invasive techniques, and inhibits the migration of liquid and particulate matter from inside a physiological cavity or opening, such as an aneurysm or a septal defect, as well as inhibiting the flow of liquid and particulate matter, such as from an associated blood vessel or chamber, into the physiological cavity or opening. The device has a closure structure that covers the neck or opening of a cavity and has one or more anchoring structures for supporting and retaining the closure structure in place across the cavity or opening.
摘要翻译：使用微创技术递送可植入闭合结构，并且抑制液体和颗粒物质从生理空腔或开口内的移动，例如动脉瘤或间隔缺损，以及抑制液体和颗粒物质的流动，例如从相关的血管或腔室进入生理腔或开口。该装置具有覆盖空腔的颈部或开口的封闭结构，并且具有一个或多个锚固结构，用于将闭合结构支撑并保持在空腔或开口上的适当位置。

5. 发明申请

US20070168020A1 Bifurcated stent and delivery system 失效
标题翻译：分叉支架和分娩系统
公开(公告)号：US20070168020A1
公开(公告)日：2007-07-19
申请号：US11726144
申请日：2007-03-21
申请人： Gregory Brucker , Enrique Malaret , Todd Hall , David Byrd , Gerald Hubbs , Gregory Furnish , Josh Barber , Indaka Gunasekara , Benjamin Morris , Valerie Futral , Sava Chernomordik , William Mers Kelly , William Reuss , Simon Furnish , Michael Wilson , Hacene Bouadi , John Muskivitch , Matthew Pease , David Rahdert , Travis Rowe , Gregory Ruhf , Brandon Walsh , Claude Vidal , Thomas Banks , Russ Redmond
发明人： Gregory Brucker , Enrique Malaret , Todd Hall , David Byrd , Gerald Hubbs , Gregory Furnish , Josh Barber , Indaka Gunasekara , Benjamin Morris , Valerie Futral , Sava Chernomordik , William Mers Kelly , William Reuss , Simon Furnish , Michael Wilson , Hacene Bouadi , John Muskivitch , Matthew Pease , David Rahdert , Travis Rowe , Gregory Ruhf , Brandon Walsh , Claude Vidal , Thomas Banks , Russ Redmond
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/954 , A61F2/958 , A61F2/966 , A61F2/97 , A61F2002/061 , A61F2002/821 , A61F2002/9583 , A61F2250/006
摘要： A bifurcated stent includes a first stent section and a second stent section. The first stent section is balloon expandable, has an unexpanded configuration, an expanded configuration, and a tubular wall defining a secondary opening. The secondary stent section is self-expanding and an end of the secondary stent section is engaged to a portion of the tubular wall of the primary stent section defining the secondary opening. The secondary stent section has an unexpanded configuration with a first length and an expanded configuration with a second length where the first length is less than the second length. The secondary stent section is expanded to the expanded configuration after the primary stent section is expanded to the expanded configuration. The secondary stent section forms a portion of the tubular wall of the primary stent section in the unexpanded configuration.
摘要翻译：分支支架包括第一支架部分和第二支架部分。第一支架部分是球囊可膨胀的，具有未膨胀的构造，膨胀的构型和限定次级开口的管状壁。辅助支架部分是自膨胀的，并且次级支架部分的端部接合到限定第二开口的主支架部分的管状壁的一部分。次级支架部分具有第一长度和第二长度的膨胀构造的未膨胀构型，其中第一长度小于第二长度。在将主支架部分扩展到扩张构型之后，将二次支架部分扩大到扩张构型。辅助支架部分以未展开的构型形成主支架部分的管状壁的一部分。

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