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1. 发明申请

US20180306839A1 NON-INTRUSIVE MONITORING 审中-公开
公开(公告)号：US20180306839A1
公开(公告)日：2018-10-25
申请号：US15767635
申请日：2016-10-14
申请人： Massachusetts Intitute of Technology
发明人： John Sebastian Donnal , James Paris , Steven B. Leeb , David Lawrence
IPC分类号： G01R15/16 , G01R21/133 , G01R29/08 , G01R35/00 , G01R21/14
CPC分类号： G01R15/165 , G01R21/133 , G01R21/14 , G01R29/085 , G01R35/005
摘要： Methods and apparatus for non-intrusive monitoring by sensing physical parameters such as electric and/or magnetic fields. Such apparatus and techniques may find application in a variety of fields, such as monitoring consumption of electricity, for example

2. 发明申请

US20130189807A1 METHODS FOR FABRICATING DEVICES INCLUDING PHOTOVOLTAIC DEVICES 有权
标题翻译：用于制造包括光伏器件的器件的方法
公开(公告)号：US20130189807A1
公开(公告)日：2013-07-25
申请号：US13714934
申请日：2012-12-14
申请人： Massachusetts Intitute of Technology
发明人： Karen K. Gleason , Vladimir Bulovic , Miles C. Barr , David C. Borrelli
IPC分类号： H01L51/00 , H01L51/56 , H01L51/42
CPC分类号： H01L51/0008 , B82Y10/00 , H01L51/0036 , H01L51/0046 , H01L51/0047 , H01L51/42 , H01L51/56 , Y02E10/549
摘要： Embodiments described herein provide methods for processing various polymer materials for use in devices, such as photovoltaic devices. In some cases, oxidative chemical vapor deposition (oCVD) may be used to process conjugated polymers, including relatively insoluble conjugated polymers. The methods described herein provide processing techniques that may be used to synthesize and/or process polymers, such as unsubstituted thiophene.
摘要翻译：本文描述的实施例提供了用于处理用于诸如光伏器件的器件的各种聚合物材料的方法。在某些情况下，氧化化学气相沉积（oCVD）可用于处理共轭聚合物，包括相对不溶的共轭聚合物。本文描述的方法提供可用于合成和/或加工聚合物的加工技术，例如未取代的噻吩。

3. 发明申请

US20180290942A1 NITROGEN FIXATION USING REFACTORED NIF CLUSTERS 审中-公开
公开(公告)号：US20180290942A1
公开(公告)日：2018-10-11
申请号：US15766122
申请日：2016-10-05
申请人： Massachusetts Intitute of Technology
发明人： Christopher A. Voigt , Min-Hyung Ryu , Mi Ryoung Song
IPC分类号： C05F11/08 , C12N15/52 , C12N15/70
摘要： The invention relates to methods for promoting fixed nitrogen from atmospheric nitrogen, and related products. Endophytic bacteria having an exogenous nif cluster promote fixed nitrogen for cereal plants.

4. 发明申请

US20180090661A1 CURRENT CROWDING IN THREE-TERMINAL SUPERCONDUCTING DEVICES AND RELATED METHODS 审中-公开
公开(公告)号：US20180090661A1
公开(公告)日：2018-03-29
申请号：US15563158
申请日：2016-04-01
申请人： MASSACHUSETTS INTITUTE OF TECHNOLOGY
发明人： Adam N. McCaughan , Karl K. Berggren , Qingyuan Zhao Zhao
IPC分类号： H01L39/10 , G11C11/44
CPC分类号： H01L39/10 , G11C11/44 , H01L39/145
摘要： An active three-terminal superconducting device having an intersection region at which a hot spot may be controllably formed is described. The intersection region may exhibit current crowding in response to imbalances in current densities applied to channels connected to intersection region. The current crowding may form a hot spot, in which the superconducting device may exhibit a measurable resistance. In some cases, a three-terminal superconducting device may be configured to sense an amount of superconducting current flowing in a channel or loop without having to perturb the superconducting state or amount of current flowing in the channel. A three-terminal superconducting device may be used to read out a number of fluxons stored in a superconducting memory element.

5. 发明申请

WO2018081502A1 SYNTHETIC BACTERIOPHAGES AND BACTERIOPHAGE COMPOSITIONS 审中-公开
标题翻译：合成的细菌和细菌组合物
公开(公告)号：WO2018081502A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/058667
申请日：2017-10-27
申请人： MASSACHUSETTS INTITUTE OF TECHNOLOGY
发明人： LU, Timothy, Kuan-Ta , LIMERE, Sebastien , YANG, Andrew, C. , YEHL, Kevin, M.
IPC分类号： G01N33/569
摘要： Disclosed herein are novel synthetic bacteriophages and bacteriophage compositions, methods of production thereof, and therapeutic uses thereof.
摘要翻译：本文公开了新型合成噬菌体和噬菌体组合物，其生产方法和其治疗用途。

6. 发明申请

WO2018067533A1 ELECTROCHEMICAL CONVERSION OF HALOGENATED COMPOUNDS AND ASSOCIATED SYSTEMS 审中-公开
标题翻译：卤代化合物及相关体系的电化学转化
公开(公告)号：WO2018067533A1
公开(公告)日：2018-04-12
申请号：PCT/US2017/054893
申请日：2017-10-03
申请人： MASSACHUSETTS INTITUTE OF TECHNOLOGY
发明人： GALLANT, Betar , LI, Yuanda , KHURRAM, Aliza , HE, Mingfu
IPC分类号： H01M4/40 , H01M4/46 , H01M4/58 , H01M4/86 , H01M6/14 , H01M12/04 , H01M12/06
CPC分类号： H01M6/14 , H01M4/40 , H01M4/46 , H01M4/582 , H01M4/8605 , H01M12/04 , H01M12/06
摘要： Methods and systems for the electrochemical conversion of halogenated compounds are provided. In some embodiments, a method comprises converting a halogenated compound (e.g., fluorinated gas) to relatively non-hazardous products via one or more electrochemical reactions. The electrochemical reaction(s) may occur under relatively mild conditions (e.g., low temperature) and/or without the aid of a catalyst. In some embodiments, the electrochemical reaction may produce a relatively large amount of energy. In some such cases, systems, described herein, may be designed to facilitate the conversion of the halogenated compound (e.g., SF6, NF3) while harnessing (e.g., storing, converting) the energy associated with the electrochemical reaction. System and methods described herein may be used in a wide variety of applications, including waste management (e.g., environmental remediation, greenhouse gas mitigation), energy recovery (e.g., industrial energy recovery), and primary batteries (e.g., metal-gas batteries).
摘要翻译：提供了用于卤化化合物的电化学转化的方法和系统。在一些实施方案中，方法包括经由一个或多个电化学反应将卤化化合物（例如氟化气体）转化为相对无害的产物。电化学反应可以在相对温和的条件下（例如低温）和/或不借助催化剂进行。在一些实施方案中，电化学反应可以产生相对大量的能量。在一些这样的情况下，本文所述的系统可以被设计成促进卤化化合物（例如，SF 6，NF 3）的转化，同时利用（例如，储存，转化）与电化学反应相关的能量。本文描述的系统和方法可以用于各种各样的应用，包括废物管理（例如，环境修复，温室气体缓解），能量回收（例如工业能量回收）和原电池（例如金属 - 气体电池）

7. 发明申请

WO2018057812A3 CONSTRUCTS FOR CONTINUOUS MONITORING OF LIVE CELLS 审中-公开
公开(公告)号：WO2018057812A3
公开(公告)日：2018-03-29
申请号：PCT/US2017/052822
申请日：2017-09-21
申请人： THE BROAD INSTITUTE, INC. , MASSACHUSETTS INTITUTE OF TECHNOLOGY
发明人： BLAINEY, Paul , BORRAJO, Jacob , NAJIA, Mohamad , DIXIT, Atray
IPC分类号： A61K39/12 , A61K39/21 , C07K14/005 , C07K14/155 , C12N7/04
摘要： The present invention provides for methods to obtain multiple information-rich samples at different time points from the same cell while minimally disrupting the cell. The subject matter disclosed herein is generally related to nucleic acid constructs for continuous monitoring of live cells. Specifically, the subject matter disclosed herein is directed to nucleic acid constructs that encode a fusion protein and a construct RNA sequence that induce live cells to self-report cellular contents while maintaining cell viability. The present invention may be used to monitor gene expression in single cells while maintaining cell viability.

8. 发明申请

WO2018017845A1 MATERIALS AND DEVICES CONTAINING HYDROGEL-ENCAPSULATED CELLS 审中-公开
标题翻译：含有水凝胶封装细胞的材料和装置
公开(公告)号：WO2018017845A1
公开(公告)日：2018-01-25
申请号：PCT/US2017/043094
申请日：2017-07-20
申请人： MASSACHUSETTS INTITUTE OF TECHNOLOGY
发明人： LU, Timothy, Kuan-ta , LIU, Xinyue , TANG, Tzu-chieh , THAM, Eleonore, Claire , ZHAO, Xuanhe
IPC分类号： C12N11/10
CPC分类号： A61K49/0097 , A61B5/6806 , A61B5/6833 , A61K49/0073 , C12N11/04 , C12N11/10 , C12N15/63 , C12N15/70 , C12Q1/6897
摘要： Provided herein, in some embodiments, are hydrogel-elastomer and hydrogel-alginate devices, compositions and associated methods to encapsulate living cells.
摘要翻译：在一些实施方案中，本文提供了包封活细胞的水凝胶 - 弹性体和水凝胶 - 藻酸盐装置，组合物和相关方法。

9. 发明申请

WO2017151915A1 VERSATILE, FLEXIBLE AND BIOCOMPATIBLE ELASTOMERIC MICROTUBES 审中-公开
标题翻译：多功能，灵活和生物弹性的弹性微管
公开(公告)号：WO2017151915A1
公开(公告)日：2017-09-08
申请号：PCT/US2017/020443
申请日：2017-03-02
申请人： NATIONAL UNIVERSITY OF SINGAPORE , MASSACHUSETTS INTITUTE OF TECHNOLOGY , SHANGHAI JIAO TONG UNIVERSITY
发明人： XI, Wang , LIM, Chwee, Teck , KONG, Fang , GONG, Xiaobo
IPC分类号： A61F2/02 , A61F2/04 , B81C1/00 , B81C99/00 , B29C67/00 , C08J7/00 , C08J7/04
摘要： The present invention relates to a flexible polymer-based microtube having an inner diameter of about 4 μm to about 1000 μm and a variable outer diameter, wherein the cross- sectional shape of the microtube can be, for instance, circular, rectangular, square, triangular, elliptical, star or irregular. The present invention also relates to a method of making the flexible microtube and devices incorporating the flexible microtube.
摘要翻译：本发明涉及具有约4μm至约1000μm的内径和可变外径的柔性聚合物基微管，其中微管的截面形状可以是，对于实例，圆形，矩形，正方形，三角形，椭圆形，星形或不规则形状。本发明还涉及制造柔性微管的方法以及包含柔性微管的装置。

10. 发明申请

WO2007019499A2 NUCLEIC ACID SEQUENCES ASSOCIATED WITH CELL STATES 审中-公开
标题翻译：与细胞状态相关的核酸序列
公开(公告)号：WO2007019499A2
公开(公告)日：2007-02-15
申请号：PCT/US2006/030887
申请日：2006-08-08
申请人： MASSACHUSETTS INTITUTE OF TECHNOLOGY , SHERLEY, James, L. , NOH, Min-soo
发明人： SHERLEY, James, L. , NOH, Min-soo
CPC分类号： C12Q1/6883 , C12Q2600/158
摘要： The present invention is directed to nucleic acid sequences whose expression is associated with different cell states, including nucleic acid sequences whose expression is induced at least 100-fold, or alternatively upregulated, in cells exhibiting asymmetric self-renewal relative to other cells. The invention is also directed to nucleic acid sequences whose expression is induced at least 100-fold, or alternatively upregulated, in cells exhibiting symmetric self-renewal relative to other cells.
摘要翻译：本发明涉及其表达与不同细胞状态相关的核酸序列，包括在其相对于其他细胞显示不对称自我更新的细胞中，其表达被诱导至少100倍或可选地上调的核酸序列。本发明还涉及其表达在相对于其他细胞显示对称自我更新的细胞中被诱导至少100倍或者可选地上调的核酸序列。

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