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    • 7. 发明授权
    • Method of separation into three components using a simulated moving bed
    • 使用模拟移动床分离成三个组分的方法
    • US5556546A
    • 1996-09-17
    • US362927
    • 1994-12-23
    • Masatake TanimuraMasao Tamura
    • Masatake TanimuraMasao Tamura
    • B01D15/18C13B20/14C13B35/06C13K1/08C13K7/00B01D15/08
    • C13B35/06B01D15/1828C13B20/144C13K1/08C13K7/00B01D2215/023
    • The method of chromatographic separation comprises: a feed-withdrawal step in which, with liquid flow being permitted from the first to the third unit beds in the simulated moving bed, an eluant is fed into the first unit bed and the feed stock is fed into the third unit bed while, at the same time, part of the effluent from the first unit bed is withdrawn from the system as a fraction rich in component B and the effluent from the third unit bed is withdrawn from the system as a fraction rich in component C; a circulation stage in which, with liquid circulation being permitted through the simulated moving bed, the liquid in the simulated moving bed is moved downstream without liquid feed to or withdrawal from the simulated moving bed; and a withdrawal stage in which, with liquid flow being permitted from the second to the first unit beds, the eluant is fed to the second unit bed and the effluent from the first unit bed is withdrawn from the system as a fraction rich in component A; wherein, after the above three stages are performed, the same stages are repeated except that feed stock and eluant are fed to, and effluents are withdrawn from unit beds which exist immediately downstream of the respective corresponding unit beds.
    • 色谱分离方法包括:进料提取步骤,其中,在模拟移动床中从第一至第三单元床允许液体流动的同时,将洗脱液送入第一单元床,并将原料进料至 第三单元床,同时来自第一单元床的部分流出物作为富含组分B的馏分从系统中排出,并且来自第三单元床的流出物作为富含馏分的馏分从系统中排出 组分C; 循环阶段,其中通过模拟移动床允许液体循环,模拟移动床中的液体向下游移动,而不进行液体馈送或从模拟移动床退出; 以及取出阶段,其中从第二单元床到第一单元床允许液体流动,将洗脱液进料到第二单元床,并且来自第一单元床的流出物作为富含组分A的馏分从系统中排出 ; 其中,在执行上述三个阶段之后,重复进行相同的步骤,除了将原料和洗脱剂进料到,并且从相应的相应单元床的紧下游存在的单元床中排出流出物。