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1. 发明授权

US06923757B2 Endoscope having a lubricant 失效
标题翻译：内窥镜具有润滑剂
公开(公告)号：US06923757B2
公开(公告)日：2005-08-02
申请号：US10152019
申请日：2002-05-22
申请人： Masanao Abe , Kazuhiko Gonda
发明人： Masanao Abe , Kazuhiko Gonda
IPC分类号： G02B23/24 , A61B1/00 , A61B1/005 , A61B1/012 , C10M169/04 , A61B1/07
CPC分类号： A61B1/00071 , A61B1/005 , A61B1/012 , C10M169/04 , C10M2201/00 , C10M2201/061 , C10M2201/062 , C10M2201/066 , C10M2201/105 , C10M2201/16 , C10M2201/18 , C10M2211/06 , C10M2213/02 , C10M2213/062 , C10M2229/04 , C10M2229/041 , C10M2229/042 , C10M2229/043 , C10M2229/044 , C10M2229/045 , C10M2229/046 , C10M2229/047 , C10M2229/048 , C10M2229/051 , C10M2229/052 , C10N2210/02 , C10N2220/02 , C10N2240/00 , C10N2240/22 , C10N2240/30 , C10N2240/50 , C10N2240/52 , C10N2240/54 , C10N2240/56 , C10N2240/58 , C10N2240/60 , C10N2240/66
摘要： An endoscope which has small bending resistance and is hard to be damaged or broken even when it is repeatedly used is disclosed. The endoscope includes a flexible insertion section 2 and an operation section 7 provided on the proximal end of the insertion section 2. The insertion section 2 has a sheath constructed from an outer layer 382 and the like, and elongated members such as an image guide 31 and light guides 32, 32 and the like are housed in lumens in the sheath. Further, each light guide 32 has an optical fiber bundle and a protective sheath 321 for protecting the optical fiber bundle. In the interior space of the protective sheath 321, a lubricant 5 containing a silicone oil and a solid lubricant is provided. The solid lubricant contains at least one of boron nitride, poly tetrafluoroethylene, and molybdenum disulfide. The solid lubricant is preferably formed into powder having an average grain size of 0.1 to 15 μm. By providing the lubricant 5 in the interior space of the lumen, bending resistance of the insertion section is reduced so that damage, breakage, or the like is hard to occur in the elongated members.
摘要翻译：公开了一种具有小弯曲阻力并且即使重复使用也难以损坏或破损的内窥镜。内窥镜包括柔性插入部2和设置在插入部2的基端的操作部7。插入部分2具有由外层382等构成的护套，并且诸如图像引导件31和导光件32,32等的细长构件容纳在护套中的管腔中。此外，每个导光体32具有用于保护光纤束的光纤束和保护套321。在保护套321的内部空间中，设置含有硅油和固体润滑剂的润滑剂5。固体润滑剂含有氮化硼，聚四氟乙烯和二硫化钼中的至少一种。优选将固体润滑剂形成为平均粒径为0.1〜15μm的粉末。通过在内腔的内部空间设置润滑剂5，减小插入部的抗弯曲性，使得在细长构件中难以发生损伤，破损等。

2. 发明授权

US06372357B1 External component of endoscope 失效
标题翻译：内窥镜外置部件
公开(公告)号：US06372357B1
公开(公告)日：2002-04-16
申请号：US09666840
申请日：2000-09-21
申请人： Shinji Hayakawa , Rensuke Adachi , Kunitoshi Ikeda , Masanao Abe
发明人： Shinji Hayakawa , Rensuke Adachi , Kunitoshi Ikeda , Masanao Abe
IPC分类号： B32B900
CPC分类号： A61B1/00066 , A61B1/0011 , A61B1/121 , C23C28/00 , C25D11/20 , Y10S428/926 , Y10S428/935 , Y10S600/92 , Y10T428/12583 , Y10T428/1259 , Y10T428/12611 , Y10T428/12736 , Y10T428/2982 , Y10T428/2991 , Y10T428/2998
摘要： An external component of an endoscope includes an aluminum alloy base member whose surface is subjected to anodic oxidation, and thereafter, is subjected to an electrolytic deposition thereon.
摘要翻译：内窥镜的外部部件具有表面进行阳极氧化的铝合金基材，然后在其上进行电解沉积。

3. 发明授权

US07163509B2 Component of endoscope and endoscope provided with the component 失效
标题翻译：配有组件的内窥镜和内窥镜的组件
公开(公告)号：US07163509B2
公开(公告)日：2007-01-16
申请号：US10737891
申请日：2003-12-18
申请人： Masanao Abe
发明人： Masanao Abe
IPC分类号： A61B1/04
CPC分类号： A61B1/00059 , A61B1/00071 , A61B1/0011 , Y10S430/146
摘要： A component of an endoscope is a flexible tube which is composed of a helical coil, a reticular tube formed of a braided thin wires and provided over the helical coil, and an outer cover provided over the reticular tube. The outer cover is formed of a resin material containing TiNxOy (where, 0.1≦x≦1.0, 0≦y≦1.9) which is a color developing agent to be colored when irradiated with laser light. The flexible tube is provided with scale formed by the colored portion. The outer surface the outer cover is black or dark color before the irradiation with laser light, but thus formed scale is white or blight color having a whiteness of 60% or more.
摘要翻译：内窥镜的组件是由螺旋线圈，由编织细线形成的网状管并设置在螺旋线圈上的柔性管，以及设置在网状管上的外罩。外盖由含有TiN x O O y Y（其中，0.1 <= x <= 1.0,0 <= y <= 1.9）的树脂材料形成，其为彩色显影剂在用激光照射时被着色。柔性管设有由着色部形成的标尺。在用激光照射之前，外盖的外表面是黑色或深色，但因此形成的白度或白度为白色或白色的比例为60％以上。

4. 发明授权

US07011627B2 Flexible tube for an endoscope and electronic endoscope equipped with the flexible tube 有权
公开(公告)号：US07011627B2
公开(公告)日：2006-03-14
申请号：US10441062
申请日：2003-05-20
申请人： Masanao Abe
发明人： Masanao Abe
IPC分类号： A61B1/00
CPC分类号： A61B1/0055
摘要： An flexible tube for an endoscope having excellent resilience and durability is provided. The flexible tube for an endoscope includes a spiral coil formed by helically winding a band-shaped member, a reticular tube formed by braiding a plurality of fine wires and provided over the spiral coil, and a flexible outer cover provided over the reticular tube. The fine wires include at least one first fine wire having a coating layer mainly made from a resin material and at least one second fine wire having no such a coating layer, and the first fine wire is made more flexible than the second fine wire. The difference between the flexibilities of the first fine wire and the second fine wire can be obtained in such a way (method) that the first fine wire is made from a constituent material softer than a constituent material of the second fine wire, or that the diameter of the first fine wire is made to be smaller than the diameter of the second fine wire, or the like.

5. 发明授权

US09156827B2 Anticancer agent 有权
标题翻译：抗癌剂
公开(公告)号：US09156827B2
公开(公告)日：2015-10-13
申请号：US13643002
申请日：2011-04-28
申请人： Tetsuo Nagano , Takayoshi Okabe , Hirotatsu Kojima , Nae Saito , Hirofumi Nakano , Masanao Abe , Akiko Tanaka , Teruki Honma , Shigeyuki Yokoyama , Keiko Tsuganezawa , Hitomi Yuki
发明人： Tetsuo Nagano , Takayoshi Okabe , Hirotatsu Kojima , Nae Saito , Hirofumi Nakano , Masanao Abe , Akiko Tanaka , Teruki Honma , Shigeyuki Yokoyama , Keiko Tsuganezawa , Hitomi Yuki
IPC分类号： C07D405/14 , A61K31/36 , A61K31/454 , A61K31/496 , A61K31/5377 , C07D405/06 , C07D493/04 , C07D413/14 , C07D417/14 , C07D471/04
CPC分类号： C07D405/14 , A61K31/36 , A61K31/454 , A61K31/496 , A61K31/5377 , C07D405/06 , C07D413/14 , C07D417/14 , C07D471/04 , C07D493/04
摘要： An anticancer agent comprising a compound represented by the formula (I) [R1 represents hydrogen atom, hydroxyl group, a C1-6 alkoxy group and the like; R2 and R3 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; R4 represents hydrogen atom, a C1-6 alkyl group, a C1-6 alkylsulfonyl group and the like; R5 represents hydrogen atom or a substituent; represents a single bond or a double bond; R6 and R7 represents hydrogen atom, a C1-6 alkyl group and the like; R8 represents hydrogen atom, a C1-6 alkyl group and the like; A represents —O—, —S—, or —CH2—; D represents —C═ or —N═; X represents methylene group, —O—, or —CO—; Q represents —N═ or —C(R8)═; and Y represents a heterocyclic group or amino group], which shows a superior inhibitory activity against pim-1 kinase.
摘要翻译：包含由式（I）表示的化合物[R 1表示氢原子，羟基，C 1-6烷氧基等]的抗癌剂， R2和R3表示氢原子，卤素原子，C1-6烷基等; R4表示氢原子，C1-6烷基，C1-6烷基磺酰基等; R5代表氢原子或取代基; 代表单键或双键; R6和R7表示氢原子，C1-6烷基等; R8表示氢原子，C1-6烷基等; A表示-O - ， - S-或-CH 2 - ; D表示-C≡或-N =; X表示亚甲基，-O-或-CO-; Q表示-N =或-C（R 8）= Y表示杂环基或氨基]，这表现出对pim-1激酶的优异抑制活性。

6. 发明申请

US20130102776A1 ANTICANCER AGENT 有权
标题翻译： ANTICANCER代理
公开(公告)号：US20130102776A1
公开(公告)日：2013-04-25
申请号：US13643002
申请日：2011-04-28
申请人： Tetsuo Nagano , Takayoshi Okabe , Hirotatsu Kojima , Nae Saito , Hirofumi Nakano , Masanao Abe , Akiko Tanaka , Teruki Honma , Shigeyuki Yokoyama , Keiko Tsuganezawa , Hitomi Yuki
发明人： Tetsuo Nagano , Takayoshi Okabe , Hirotatsu Kojima , Nae Saito , Hirofumi Nakano , Masanao Abe , Akiko Tanaka , Teruki Honma , Shigeyuki Yokoyama , Keiko Tsuganezawa , Hitomi Yuki
IPC分类号： C07D405/14 , C07D493/04 , C07D413/14 , C07D471/04 , C07D417/14 , C07D405/06
CPC分类号： C07D405/14 , A61K31/36 , A61K31/454 , A61K31/496 , A61K31/5377 , C07D405/06 , C07D413/14 , C07D417/14 , C07D471/04 , C07D493/04
摘要： An anticancer agent comprising a compound represented by the formula (I) [R1 represents hydrogen atom, hydroxyl group, a C1-6 alkoxy group and the like; R2 and R3 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; R4 represents hydrogen atom, a C1-6 alkyl group, a C1-6 alkylsulfonyl group and the like; R5 represents hydrogen atom or a substituent; represents a single bond or a double bond; R6 and R7 represents hydrogen atom, a C1-6 alkyl group and the like; R8 represents hydrogen atom, a C1-6 alkyl group and the like; A represents —O—, —S—, or —CH2—; D represents —C═ or —N═; X represents methylene group, —O—, or —CO—; Q represents —N═ or —C(R8)═; and Y represents a heterocyclic group or amino group], which shows a superior inhibitory activity against pim-1 kinase.
摘要翻译：包含由式（I）表示的化合物[R 1表示氢原子，羟基，C 1-6烷氧基等]的抗癌剂， R2和R3表示氢原子，卤素原子，C1-6烷基等; R4表示氢原子，C1-6烷基，C1-6烷基磺酰基等; R5代表氢原子或取代基; 代表单键或双键; R6和R7表示氢原子，C1-6烷基等; R8表示氢原子，C1-6烷基等; A表示-O - ， - S-或-CH 2 - ; D表示-C =或-N =; X表示亚甲基，-O-或-CO-; Q表示-N =或-C（R8）=; Y表示杂环基或氨基]，这表现出对pim-1激酶的优异抑制活性。

7. 发明授权

US5768940A Sample collector 失效
标题翻译：样品收集器
公开(公告)号：US5768940A
公开(公告)日：1998-06-23
申请号：US848731
申请日：1997-05-22
申请人： Junichiro Kawaguchi , Akira Fujiwara , Shujiro Sawai , Masanao Abe , Akiko Nakamura
发明人： Junichiro Kawaguchi , Akira Fujiwara , Shujiro Sawai , Masanao Abe , Akiko Nakamura
IPC分类号： B64G1/66 , B64G4/00 , E21B7/00 , E21B49/02 , G01N1/04 , G01N1/08
CPC分类号： B64G4/00 , B64G1/66 , E21B49/02 , E21B7/007 , G01N1/04 , B64G2001/1064
摘要： A sample collector of this invention includes a projectile projecting unit n which a projectile is loaded and which has a projecting outlet for projecting out the projectile loaded therein, an enclosed container which is communicated with the projecting outlet of the projectile projecting unit, which has a projectile passing hole arranged at a position located away from the projecting outlet, the passing hole allowing the projectile to pass through it after the projectile is projected out from the projecting outlet, and which covers a space between the projecting outlet of the projectile projecting unit, and a kinetic energy absorbing mechanism which is arranged around a projectile path between the projecting outlet of the projectile projecting unit and the projectile passing hole of the enclosed container. The kinetic energy absorbing mechanism may be an independent active type such as brushes or an integral passive type structured by a part of the container.
摘要翻译：本发明的取样器包括：弹丸投射单元，其中装有弹丸，并且具有用于突出装载在其中的弹丸的突出出口，与弹丸投射单元的突出出口连通的封闭容器，抛射物通过孔布置在远离突出出口的位置处，通过孔允许射弹在突出的出口突出之后穿过突出的出射孔，并且覆盖射弹投影单元的突出出口之间的空间，以及围绕弹丸投射单元的突出出口与封闭容器的射弹通孔之间的射弹路径布置的动能吸收机构。动能吸收机构可以是独立的主动类型，例如由容器的一部分构成的刷子或整体被动型。

8. 发明授权

US07484433B2 Shift lever apparatus 有权
标题翻译：换档杆装置
公开(公告)号：US07484433B2
公开(公告)日：2009-02-03
申请号：US11017193
申请日：2004-12-21
申请人： Tetuya Arakawa , Ryoichi Fujiwara , Susumu Sakaba , Masanao Abe
发明人： Tetuya Arakawa , Ryoichi Fujiwara , Susumu Sakaba , Masanao Abe
IPC分类号： G05G1/00
CPC分类号： F16H63/42 , F16H2063/423 , Y10T74/2093
摘要： A shift lever apparatus for changing the change-speed ranges of a transmission of an automotive vehicle. The shift lever apparatus includes an indicator panel indicating positions which respectively correspond to the change-speed ranges. A slide member is provided to be movable in relation to a shift lever. A guide device is disposed to slidably guide the slide member and includes a descending guide section which allows the slide member to be guided to separate downward from the indicator panel. A mark piece is provided to indicate one of the positions of the indicator panel to represent the present change-speed range of the transmission. Additionally, a support member is fixedly connected to at least the major part of the slide member. The support member is free from following deformation of the slide member. The mark piece is fixedly connected to the support member.
摘要翻译：一种用于改变机动车辆的变速器的变速范围的变速杆装置。变速杆装置包括指示面板，其指示分别对应于变速范围的位置。滑动构件设置成可相对于换档杆移动。引导装置被设置成可滑动地引导滑动构件，并且包括允许滑动构件被引导以从指示器面板向下分离的下降引导部。提供标记件以指示指示器面板的一个位置以表示变速器的当前变速范围。此外，支撑构件固定地连接到滑动构件的至少主要部分。支撑构件没有跟随滑动构件的变形。标记件固定地连接到支撑构件。

9. 发明授权

US07169105B2 Flexible tube for an endoscope 有权
标题翻译：内窥镜柔性管
公开(公告)号：US07169105B2
公开(公告)日：2007-01-30
申请号：US10822651
申请日：2004-04-13
申请人： Kikuo Iwasaka , Tadashi Kasai , Hideo Nanba , Masaru Takeshige , Akira Sugiyama , Keiji Kunii , Masanao Abe
发明人： Kikuo Iwasaka , Tadashi Kasai , Hideo Nanba , Masaru Takeshige , Akira Sugiyama , Keiji Kunii , Masanao Abe
IPC分类号： A61B1/005
CPC分类号： B32B27/08 , A61B1/00071 , A61B1/005 , A61L29/085 , A61L29/12 , B32B1/08 , B32B3/10 , B32B3/30 , B32B7/02 , B32B27/32 , B32B27/36 , B32B27/40 , B32B2307/51 , B32B2597/00 , C08L75/04 , C08L27/12 , C08L25/06 , C08L23/00 , C08L67/00
摘要： A flexible tube for an endoscope has an elongated tubular core body, and an outer cover which is provided over the core body. The outer cover is composed of an inner layer, an outer layer and at least one intermediate layer. In this flexible tube, any one of the layers is different from one of the other layers in its property. Further, at least one of the layers has a thickness-varying region where the thickness of the layer varies in its longitudinal direction. In addition, the inner layer of the outer cover has projections which are integrally formed on the inner layer so that the projections project into holes and/or the recesses formed on the core body. This structure makes it possible to produce a flexible tube for an endoscope that has high durability, high flexibility and high chemical resistance as well as excellent operationability.
摘要翻译：用于内窥镜的柔性管具有细长的管状芯体和设置在芯体上的外盖。外盖由内层，外层和至少一层中间层构成。在这种柔性管中，任何一个层在其性质上与其它层之一不同。此外，层中的至少一个具有厚度变化区域，其中层的厚度在其纵向方向上变化。此外，外盖的内层具有一体地形成在内层上的凸起，使得凸起突出到形成在芯体上的孔和/或凹部中。该结构使得可以制造具有高耐久性，高柔韧性和高耐化学性以及优异的可操作性的用于内窥镜的柔性管。

10. 发明申请

US20060162105A1 Cleaning brush for endoscopes 审中-公开
标题翻译：内窥镜清洁刷
公开(公告)号：US20060162105A1
公开(公告)日：2006-07-27
申请号：US11326473
申请日：2006-01-06
申请人： Masanao Abe
发明人： Masanao Abe
IPC分类号： B08B9/04
CPC分类号： A61B1/122 , A46B5/0062 , A46B2200/3013
摘要： A cleaning brush for endoscopes is used for cleaning an inner surface of a channel formed inside an endoscope and it is capable of preventing splash of dirt or cleaning liquid caused by removing a brush portion from a channel reliably. The cleaning brush includes an elongated body portion having flexibility so as to be able to bend along an inner wall of the channel when being inserted into the channel, at least one brush portion provided on the body portion at the side of the tip end thereof; and a protruding portion provided on the body portion so as to protrude from the tip end of the body portion in a longitudinal direction thereof, the protruding portion being adapted to make contact with the inner surface of the channel to prevent or suppress the brush portion from swinging or springing when the brush portion is removed from the channel, wherein the length of the protruding portion is longer than the length of the brush portion.
摘要翻译：用于内窥镜的清洁刷用于清洁形成在内窥镜内部的通道的内表面，并且其能够防止由于可靠地从通道中除去刷部而引起的污垢或清洁液的飞溅。清洁刷包括细长主体部分，其具有柔性，以便当插入通道时能够沿着通道的内壁弯曲，至少一个刷部分设置在主体部分的顶端侧; 以及突出部，其设置在所述主体部上，以从其主体部的前端沿其长度方向突出，所述突出部适于与所述通道的内表面接触，以防止或抑制所述刷部当刷子部分从通道移除时摆动或弹起，其中突出部分的长度长于刷部分的长度。

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