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    • 4. 发明授权
    • Blood pressure monitoring system
    • 血压监测系统
    • US5099853A
    • 1992-03-31
    • US204555
    • 1988-05-02
    • Masahiro UemuraHideichi TsudaHifumi Yokoe
    • Masahiro UemuraHideichi TsudaHifumi Yokoe
    • A61B5/022G06F17/00
    • A61B5/022A61B5/02116A61B5/02225
    • It is desirable to minimize discomfort of a living body due to pressing by a blood pressure monitoring system of a type which monitors the blood pressure of the living body for a long period of time. The present invention is constituted by including pulse wave detecting device for detecting pulse waves of an arterial vessel of a living body, blood pressure measuring device for measuring an actual blood pressure of the living body, and control device for determining a relationship between the pulse waves detected by the pulse wave detecting device and the actual blood pressure measured by the blood pressure measuring device, determining blood pressures according to the thus-determined relationship and based on the pulse waves, and commanding a display to continuously display the thus-determined blood pressures thereon. In accordance with the present invention, blood pressures are determined according to the relationship between the actual blood pressure and the pulse waves, which is determined by the control device, and based on the pulse waves, and the thus determined blood pressures are continuously displayed, thereby eliminating the operation of successively obtaining measurements of the actual blood pressure by using a cuff, for example, and minimizing discomfort felt by the living body.
    • 5. 发明授权
    • Sphygmomanometer with an arrhythmia detecting mechanism
    • 具有心律失常检测机制的血压计
    • US4262674A
    • 1981-04-21
    • US963966
    • 1978-11-27
    • Masahiro UemuraChikao HaradaKenichi SakuradoTsunehito Kakumu
    • Masahiro UemuraChikao HaradaKenichi SakuradoTsunehito Kakumu
    • A61B5/022A61B5/024A61B5/02
    • A61B5/02208A61B5/024
    • A sphygmomanometer having a built-in arrhythmia detecting mechanism, wherein the blood pressure measuring portion contains a pulsation detector, which receives pulse sounds including Korotkoff sounds for electrically converting the pulse sounds into wave form signals of the vascular pulse wave and output the same, and a mechanism indicating the blood pressure value by means of detecting the Korotkoff sounds recognized and separated from the wave form signals of the vascular pulse wave output in the above-mentioned way; the incorporated arrhythmia detecting mechanism receives the wave form signals of the vascular pulse wave for comparing the cycle of the wave form signals with a predetermined criterion in order to electrically detect irregularities, if any, in the signals for detecting the existence of arrhythmias. This sphygmomanometer is capable of measuring the blood pressure simultaneously with the detecting of arrhythmia.
    • 一种具有内置心律失常检测机构的血压计,其中,所述血压测量部分包含脉动检测器,其接收包括Korotkoff声音的脉冲声音,用于将所述脉冲声音电转换成所述血管脉搏波的波形信号并将其输出; 通过检测以上述方式从血管脉搏波输出的波形信号识别和分离的Korotkoff声音来指示血压值的机构; 结合的心律失常检测机构接收血管脉搏波的波形信号,用于将波形信号的周期与预定标准进行比较,以便电检测用于检测心律失常存在的信号中的不规则性(如果有的话)。 该血压计能够与心律失常检测同时测量血压。
    • 6. 发明授权
    • Production process for hydroxyalkyl (meth) acrylate
    • US07045651B2
    • 2006-05-16
    • US10435992
    • 2003-05-12
    • Tokumasa IshidaMasahiro Uemura
    • Tokumasa IshidaMasahiro Uemura
    • C07C67/26
    • C07C67/26C07C69/54
    • The present invention provides a novel production process for a hydroxyalkyl (meth)acrylate, in which it is possible that: in a batch reaction system, the amount of the hydroxyalkyl (meth)acrylate (which is the objective product) as produced is kept nearly on the same level as conventional and further, at the same time, there is suppressed the side production of the alkylene oxide's diaddition product (dialkylene glycol mono(meth)acrylate) that lowers the purity of the product to thus give a bad influence upon its quality. The present invention production process comprises the step of carrying out a batch reaction between (meth)acrylic acid and an alkylene oxide in the presence of a catalyst in order to produce the hydroxyalkyl (meth)acrylate; with the production process being characterized by arranging that the reaction should be initiated in a state of a catalyst concentration of more than 1, wherein the catalyst concentration is defined as the amount of the catalyst as used relative to the integrated amount of the (meth)acrylic acid as supplied and is assumed to be 1 in terms of the amount of the entire catalyst to be used relative to the amount of the entire (meth)acrylic acid to be supplied.
    • 8. 发明授权
    • Production process for hydroxyalkyl (meth)acrylate
    • (甲基)丙烯酸羟烷基酯的制备方法
    • US06465681B2
    • 2002-10-15
    • US10021061
    • 2001-12-19
    • Masahiro UemuraTokumasa IshidaYukihiro YonedaTetsuya KajiharaYasuhiro ShingaiTadayoshi Kawashima
    • Masahiro UemuraTokumasa IshidaYukihiro YonedaTetsuya KajiharaYasuhiro ShingaiTadayoshi Kawashima
    • C07C6726
    • C07C67/26C07C69/54
    • The present invention provides: a production process for a hydroxyalkyl(meth)acrylate, which can raise productivity together with avoiding danger of explosion, and further can suppress side-formation of impurities such as a diester or a monoester wherein the impurities have a bad influence on product quality. When the time from the start of adding an alkylene oxide (AO) till the end of supplying the entirety of the AO is defined as T (hour), the amount of more than 50% of the entirety of the AO is supplied before T/2 (hour) has passed since the start of adding the AO. In addition, when the total amount of an AO as supplied and the time from the start of adding the AO till the end of supplying the entirety of the AO are defined as W (mol) and T (hour) respectively, the supply of the AO is started at a supplying speed V0 (mol/hour) that is faster than the average supplying speed V (=W/T) (mol/hour), and thereafter the supplying speed of the AO is decreased at least once, and then the supply of the entirety of the AO is completed for T (hour) from the start of adding the AO.
    • 本发明提供:(甲基)丙烯酸羟烷基酯的制造方法,其能够提高生产率,同时避免爆炸的危险,并且还可以抑制杂质如杂质影响不良的杂质的副产物 对产品质量。 当从添加烯化氧(AO)开始直到提供AO全部结束时的时间定义为T(小时)时,超过全部AO的50%的量在T / 从加入AO开始,已经过了2(小时)。 此外,当供应的AO的总量和从AO的添加开始到提供AO的全部的时间分别被定义为W(mol)和T(小时)时, AO以比平均供给速度V(= W / T)(mol /小时)快)的供给速度V0(mol /小时)开始,此后AO的供给速度至少减少一次,然后 从添加AO开始,T(小时)完成AO的整体供应。
    • 9. 发明授权
    • Method of arrhythmia detection with detecting mechanism
    • 用检测机制检测心律失常的方法
    • US4356827A
    • 1982-11-02
    • US187723
    • 1980-09-16
    • Masahiro UemuraChikao HaradaKenichi SakuradoTsunehito Kakamu
    • Masahiro UemuraChikao HaradaKenichi SakuradoTsunehito Kakamu
    • A61B5/022A61B5/024A61B5/02
    • A61B5/02208A61B5/024
    • A method of using a sphygmomanometer having a built-in arrhythmia detecting mechanism, wherein the blood pressure measuring portion contains a pulsation detector, which receives pulse sounds including Korotkoff sounds for electrically converting the pulse sounds into wave form signals of the vascular pulse wave and output the same, and a mechanism indicating the blood pressure value by means of detecting the Korotkoff sounds recognized and separated from the wave form signals of the vascular pulse wave output in the above-mentioned way; the incorporated arrhythmia detecting mechanism receives the wave form signals of the vascular pulse wave for comparing the cycle of the wave form signals with a predetermined criterion in order to electrically detect irregularities, if any, in the signals for detecting the existence of arrhythmias. This sphygmomanometer is capable of measuring the blood pressure simultaneously with the detecting of arrhythmia.
    • 一种使用具有内置心律失常检测机构的血压计的方法,其中,所述血压测量部包含脉搏检测器,所述脉搏检测器接收包含Korotkoff声音的脉冲声音,用于将所述脉冲声音电转换成血管脉搏波的波形信号,并输出 以及通过检测以上述方式输出的血管脉搏波的波形信号识别和分离的Korotkoff声音来指示血压值的机构; 结合的心律失常检测机构接收血管脉搏波的波形信号,用于将波形信号的周期与预定标准进行比较,以便电检测用于检测心律失常存在的信号中的不规则性(如果有的话)。 该血压计能够与心律失常检测同时测量血压。
    • 10. 发明申请
    • Processes for Producing Hydroxyalkyl (Meth) Acrylate
    • 生产羟烷基(甲基)丙烯酸酯的方法
    • US20080154060A1
    • 2008-06-26
    • US11659370
    • 2005-08-05
    • Tokumasa IshidaHiroyuki TakakiMasahiro Uemura
    • Tokumasa IshidaHiroyuki TakakiMasahiro Uemura
    • C07C59/42
    • C07C67/26C07C69/54
    • Processes for producing a hydroxyalkyl(meth)acrylate which comprise reacting (meth)acrylic acid with an alkylene oxide in the presence of a catalyst. A first process is characterized in that the amount of the acid ingredient is kept, on calculation, at 0.010 or more in terms of molar ratio to the catalyst present in the liquid reaction mixture and that the liquid reaction mixture from which the hydroxyalkyl(meth)acrylate has been distilled off is used in the subsequent reaction. A second process is characterized in that a dialkylene glycol mono(meth)acylate is supplied to the reaction system to cause the dialkyleneglycol mono(meth)acylate to coexist in the liquid reaction mixture.
    • 制备(甲基)丙烯酸羟烷基酯的方法,其包括在催化剂存在下使(甲基)丙烯酸与烯化氧反应。 第一种方法的特征在于,根据计算,按照与液体反应混合物中存在的催化剂的摩尔比计算酸成分的量为0.010以上,并且其中(甲基)丙烯酸羟烷基酯的液体反应混合物, 蒸馏出的丙烯酸酯用于随后的反应。 第二种方法的特征在于向反应体系中加入单(甲基)丙烯酸二亚烷基二醇酯,以使液体反应混合物中的二烷基二醇单(甲基)酰化物共存。