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1. 发明申请

US20110288590A1 IMPLANTABLE VERTEBRAL FRAME SYSTEMS AND RELATED METHODS FOR SPINAL REPAIR 有权
标题翻译：可植入的VERTEBRAR框架系统及相关的脊柱修复方法
公开(公告)号：US20110288590A1
公开(公告)日：2011-11-24
申请号：US12783499
申请日：2010-05-19
申请人： Desmond O'Farrell , Andrew J. Rodenhouse , Mark E. Zyzelewski
发明人： Desmond O'Farrell , Andrew J. Rodenhouse , Mark E. Zyzelewski
IPC分类号： A61B17/70 , A61B17/88
CPC分类号： A61B17/7059 , A61B17/8042 , A61F2/4455 , A61F2002/30517
摘要： The invention relates generally to systems and methods for securing adjacent vertebrae in a fixed spacial relationship. In one embodiment, the system includes at least one interbody repair implant, at least one implantable vertebral frame and at least one retention member. In this embodiment, the interbody repair implant is sized to fit in an intervertebral space. The at least one implantable vertebral frame is configured to span between the adjacent vertebrae. The frame is also configured to attach to each of the adjacent vertebra to postoperatively maintain a desired spatial relationship between the vertebrae. The frame has at least one internal aperture there-through for providing visual access to at least a portion of the interbody repair implant, both intra-operatively and post-operatively. Methods of fusing two or more adjacent vertebral bodies in a portion of a spinal column are also disclosed. One such method includes the steps of inserting an interbody repair implant into a intervertebral space, securing an implantable vertebral fixation frame to the adjacent vertebral bodies over the implant, installing a retention member to the frame to cover at least a portion of the aperture, and moving a locking portion of the retention member from an unlocked position to a locked position.
摘要翻译：本发明一般涉及用于以固定的空间关系固定相邻椎骨的系统和方法。在一个实施例中，系统包括至少一个椎间体修复植入物，至少一个可植入椎骨框架和至少一个保持构件。在该实施例中，体内修复植入物的尺寸设置成适合于椎间空间。所述至少一个可植入椎骨框架构造成跨越相邻椎骨之间。框架还被配置为附接到每个相邻的椎骨以在术后保持椎骨之间期望的空间关系。该框架具有至少一个内孔，用于在手术中和手术后两者中提供至少一部分体内修复植入物的视觉通路。还公开了在脊柱的一部分中融合两个或更多个相邻椎体的方法。一种这样的方法包括以下步骤：将椎间体修复植入物插入到椎间空间中，将可植入的椎骨固定框架固定在植入物上的相邻椎体上，将保持构件安装到框架以覆盖孔的至少一部分，以及将保持构件的锁定部分从解锁位置移动到锁定位置。

2. 发明授权

US07651520B2 Means and method for the accurate placement of a stent at the ostium of an artery 有权
标题翻译：支架在动脉口的准确放置的方法和方法
公开(公告)号：US07651520B2
公开(公告)日：2010-01-26
申请号：US11975196
申请日：2007-10-18
申请人： Robert E. Fischell , Tim A. Fischell , David R. Fischell , Mark E. Zyzelewski
发明人： Robert E. Fischell , Tim A. Fischell , David R. Fischell , Mark E. Zyzelewski
IPC分类号： A61F2/06 , A61M25/01
CPC分类号： A61F2/95 , A61F2002/821 , A61F2250/0098
摘要： Disclosed is an ostial stent positioner that has the form of a wire for most of its length and having a short cylinder with a longitudinal slit and expandable legs situated at the positioner's distal end. The slit cylinder with its attached wire acts as an introducer sheath to introduce a stent delivery system with a stent into the artery that is to be stented. A second aspect of the present invention is a method for accurately placing a stent at the ostium of an artery that would have an ostial stenosis. Examples of such arteries that have ostial stenoses are the right and left main coronary arteries, a saphenous vein graft as used in coronary bypass surgery and the renal arteries. Also disclosed are designs for the slit cylinder that provides a variable diameter so as to fit snugly within guiding catheters having different inside diameters.
摘要翻译：公开了一种口腔支架定位器，其具有大部分长度的线的形式，并且具有短圆柱体，其具有位于定位器的远端处的纵向狭缝和可扩展腿。具有连接线的狭缝圆柱体用作导引鞘，以将具有支架的支架输送系统引入到要被固定的动脉中。本发明的第二方面是一种将支架精确地放置在具有口腔狭窄的动脉的口处的方法。具有口腔狭窄的这种动脉的实例是右冠状动脉和左主动脉冠状动脉，用于冠状动脉旁路手术的隐静脉移植物和肾动脉。还公开了用于狭缝筒的设计，其提供可变直径，以便紧密地配合在具有不同内径的引导导管内。

3. 发明申请

US20130238028A1 IMPLANTABLE VERTEBRAL FRAME SYSTEMS AND RELATED METHODS FOR SPINAL REPAIR 审中-公开
标题翻译：可植入的VERTEBRAR框架系统及相关的脊柱修复方法
公开(公告)号：US20130238028A1
公开(公告)日：2013-09-12
申请号：US13868856
申请日：2013-04-23
申请人： Desmond O'Farrell , Andrew J. Rodenhouse , Mark E. Zyzelewski
发明人： Desmond O'Farrell , Andrew J. Rodenhouse , Mark E. Zyzelewski
IPC分类号： A61B17/70
CPC分类号： A61B17/7059 , A61B17/8042 , A61F2/4455 , A61F2002/30517
摘要： The invention relates generally to systems and methods for securing adjacent vertebrae in a fixed spacial relationship. In one embodiment, the system includes at least one interbody repair implant, at least one implantable vertebral frame and at least one retention member. In this embodiment, the interbody repair implant is sized to fit in an intervertebral space. The at least one implantable vertebral frame is configured to span between the adjacent vertebrae. The frame is also configured to attach to each of the adjacent vertebra to postoperatively maintain a desired spatial relationship between the vertebrae. The frame has at least one internal aperture there-through for providing visual access to at least a portion of the interbody repair implant, both intra-operatively and post-operatively. Methods of fusing two or more adjacent vertebral bodies in a portion of a spinal column are also disclosed. One such method includes the steps of inserting an interbody repair implant into a intervertebral space, securing an implantable vertebral fixation frame to the adjacent vertebral bodies over the implant, installing a retention member to the frame to cover at least a portion of the aperture, and moving a locking portion of the retention member from an unlocked position to a locked position.
摘要翻译：本发明一般涉及用于以固定的空间关系固定相邻椎骨的系统和方法。在一个实施例中，系统包括至少一个椎间体修复植入物，至少一个可植入椎骨框架和至少一个保持构件。在该实施例中，体内修复植入物的尺寸设置成适合于椎间空间。所述至少一个可植入椎骨框架构造成跨越相邻椎骨之间。框架还被配置为附接到每个相邻的椎骨以在术后保持椎骨之间期望的空间关系。该框架具有至少一个内孔，用于在手术中和手术后两者中提供至少一部分体内修复植入物的视觉通路。还公开了在脊柱的一部分中融合两个或更多个相邻椎体的方法。一种这样的方法包括以下步骤：将椎间体修复植入物插入到椎间空间中，将可植入的椎骨固定框架固定在植入物上的相邻椎体上，将保持构件安装到框架以覆盖孔的至少一部分，以及将保持构件的锁定部分从解锁位置移动到锁定位置。

4. 发明授权

US08425569B2 Implantable vertebral frame systems and related methods for spinal repair 有权
标题翻译：植入式椎体框架系统及脊柱修复相关方法
公开(公告)号：US08425569B2
公开(公告)日：2013-04-23
申请号：US12783499
申请日：2010-05-19
申请人： Desmond O'Farrell , Andrew J. Rodenhouse , Mark E. Zyzelewski
发明人： Desmond O'Farrell , Andrew J. Rodenhouse , Mark E. Zyzelewski
IPC分类号： A61B17/70 , A61B17/88
CPC分类号： A61B17/7059 , A61B17/8042 , A61F2/4455 , A61F2002/30517
摘要： The invention relates generally to systems and methods for securing adjacent vertebrae in a fixed spacial relationship. In one embodiment, the system includes at least one interbody repair implant, at least one implantable vertebral frame and at least one retention member. In this embodiment, the interbody repair implant is sized to fit in an intervertebral space. The at least one implantable vertebral frame is configured to span between the adjacent vertebrae. The frame is also configured to attach to each of the adjacent vertebra to postoperatively maintain a desired spatial relationship between the vertebrae. The frame has at least one internal aperture there-through for providing visual access to at least a portion of the interbody repair implant, both intra-operatively and post-operatively. Methods of fusing two or more adjacent vertebral bodies in a portion of a spinal column are also disclosed. One such method includes the steps of inserting an interbody repair implant into a intervertebral space, securing an implantable vertebral fixation frame to the adjacent vertebral bodies over the implant, installing a retention member to the frame to cover at least a portion of the aperture, and moving a locking portion of the retention member from an unlocked position to a locked position.
摘要翻译：本发明一般涉及用于以固定的空间关系固定相邻椎骨的系统和方法。在一个实施例中，系统包括至少一个椎间体修复植入物，至少一个可植入椎骨框架和至少一个保持构件。在该实施例中，体内修复植入物的尺寸设置成适合于椎间空间。所述至少一个可植入椎骨框架构造成跨越相邻椎骨之间。框架还被配置为附接到每个相邻的椎骨以在术后保持椎骨之间期望的空间关系。该框架具有至少一个内孔，用于在手术中和手术后两者中提供至少一部分体内修复植入物的视觉通路。还公开了在脊柱的一部分中融合两个或更多个相邻椎体的方法。一种这样的方法包括以下步骤：将椎间体修复植入物插入到椎间空间中，将可植入的椎骨固定框架固定在植入物上的相邻椎体上，将保持构件安装到框架以覆盖孔的至少一部分，以及将保持构件的锁定部分从解锁位置移动到锁定位置。

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