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1. 发明授权

US09063090B2 Method for fabricating thin-film structure magnetizable bead detector 有权
标题翻译：制造薄膜结构磁化珠检测器的方法
公开(公告)号：US09063090B2
公开(公告)日：2015-06-23
申请号：US12284989
申请日：2008-09-26
申请人： Mark C. Tondra
发明人： Mark C. Tondra
IPC分类号： G01R33/09 , G01N27/74 , G01R33/12
CPC分类号： G01N27/745 , G01R33/09 , G01R33/1269 , Y10T29/49002 , Y10T29/49007 , Y10T29/4902
摘要： A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding to the selected molecular species held on a magnetic particle. The magnetic field sensor can be substantially covered by an electrical insulating layer having a recess therein adjacent to the sensor in which the binding molecule layer is provided. A thin-film channel structure to the sensor is supported on the substrate that can be accompanied by a reservoir structure, and an electrical interconnection conductor is supported on the substrate at least in part between the sensor and the substrate, and is electrically connected to the sensor. The magnetic field sensor can be provided in a bridge circuit, and can be formed by a number of interconnected individual sensors.
摘要翻译：一种用于检测选定分子种类存在的基于铁磁薄膜的磁场检测系统。支撑在基板上的磁场传感器具有位于其一侧上的结合分子层，其能够选择性地结合保持在磁性颗粒上的所选择的分子种类。磁场传感器可以基本上被电绝缘层覆盖，该电绝缘层在其中设置有结合分子层的传感器附近具有凹部。传感器的薄膜通道结构被支撑在基板上，该基板可以伴随着储存器结构，并且电互连导体至少部分地被支撑在基板上，并且与传感器和基板之间电连接传感器。磁场传感器可以设置在桥式电路中，并且可以由多个互连的单独的传感器形成。

2. 发明申请

US20080218157A1 Magnetic particle flow detector 有权
标题翻译：磁性粒子流量检测器
公开(公告)号：US20080218157A1
公开(公告)日：2008-09-11
申请号：US12152183
申请日：2008-05-13
申请人： Mark C. Tondra , John M. Anderson , David J. Brownell , Anthony D. Popple
发明人： Mark C. Tondra , John M. Anderson , David J. Brownell , Anthony D. Popple
IPC分类号： G01N27/74
CPC分类号： G01V3/08 , G01R33/1276 , Y10S977/932 , Y10S977/933 , Y10S977/934
摘要： A ferromagnetic thin-film based magnetic field detection system having a substrate supporting a magnetic field sensor in a channel with a first electrical conductor supported on the substrate positioned at least in part along the channel gap and in direct contact with at least some surface of the magnetic field sensor and a second electrical conductor supported on the substrate positioned at least in part along the channel gap in a region thereof adjacent to, but separated from, the magnetic field sensor.
摘要翻译：一种基于铁磁薄膜的磁场检测系统，其具有在通道中支撑磁场传感器的基板，所述基板支撑在所述基板上，所述第一电导体至少部分地沿着所述通道间隙位于所述基板上，并且与所述第一电导体的至少一些表面直接接触磁场传感器和支撑在基板上的第二电导体，其位于与磁场传感器相邻但与之隔离的区域中至少部分地沿着沟道间隙定位。

3. 发明授权

US07238539B2 Magnetizable bead detector 有权
标题翻译：磁珠检测仪
公开(公告)号：US07238539B2
公开(公告)日：2007-07-03
申请号：US10894763
申请日：2004-07-20
申请人： Mark C. Tondra
发明人： Mark C. Tondra
IPC分类号： C12Q1/68 , G01N33/553 , G01N33/558 , B01J7/00
CPC分类号： G01N27/745 , G01R33/09 , G01R33/1269 , Y10T29/49002 , Y10T29/49007 , Y10T29/4902
摘要： A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding to the selected molecular species. The magnetic field sensor can be substantially covered by an electrical insulating layer having a recess therein adjacent to the sensor in which the binding molecule layer is provided. An electrical interconnection conductor can be supported on the substrate at least in part between the sensor and the substrate, and is electrically connected to the sensor. The magnetic field sensor can be provided in a bridge circuit, and can be formed by a number of interconnected individual sensors.
摘要翻译：一种用于检测选定分子种类存在的基于铁磁薄膜的磁场检测系统。负载在基板上的磁场传感器具有位于其能够选择性地结合所选择的分子种类的一侧的结合分子层。磁场传感器可以基本上被电绝缘层覆盖，该电绝缘层在其中设置有结合分子层的传感器附近具有凹部。电互连导体可以至少部分地在传感器和基板之间被支撑在基板上，并且电连接到传感器。磁场传感器可以设置在桥式电路中，并且可以由多个互连的单独的传感器形成。

4. 发明授权

US07609054B2 Magnetic particle flow detector 有权
标题翻译：磁性粒子流量检测器
公开(公告)号：US07609054B2
公开(公告)日：2009-10-27
申请号：US12152183
申请日：2008-05-13
申请人： Mark C. Tondra , John M. Anderson , David J. Brownell , Anthony D. Popple
发明人： Mark C. Tondra , John M. Anderson , David J. Brownell , Anthony D. Popple
IPC分类号： G01N27/74 , G01R33/12
CPC分类号： G01V3/08 , G01R33/1276 , Y10S977/932 , Y10S977/933 , Y10S977/934
摘要： A ferromagnetic thin-film based magnetic field detection system having a substrate supporting a magnetic field sensor in a channel with a first electrical conductor supported on the substrate positioned at least in part along the channel gap and in direct contact with at least some surface of the magnetic field sensor ands a second electrical conductor supported on the substrate positioned at least in part along the channel gap in a region thereof adjacent to, but separated from, the magnetic field sensor.
摘要翻译：一种基于铁磁薄膜的磁场检测系统，其具有在通道中支撑磁场传感器的基板，所述基板支撑在所述基板上，所述第一电导体至少部分地沿着所述通道间隙位于所述基板上，并且与所述第一电导体的至少一些表面直接接触磁场传感器和支撑在基板上的第二电导体，该第二电导体至少部分地沿着与磁场传感器相邻但与之隔离的区域中的沟槽间隙定位。

5. 发明授权

US07391091B2 Magnetic particle flow detector 有权
标题翻译：磁性粒子流量检测器
公开(公告)号：US07391091B2
公开(公告)日：2008-06-24
申请号：US11241771
申请日：2005-09-29
申请人： Mark C. Tondra , John M. Anderson , David J. Brownell , Anthony D. Popple
发明人： Mark C. Tondra , John M. Anderson , David J. Brownell , Anthony D. Popple
IPC分类号： H01L29/02
CPC分类号： G01V3/08 , G01R33/1276 , Y10S977/932 , Y10S977/933 , Y10S977/934
摘要： A ferromagnetic thin-film based magnetic field detection system having a substrate supporting a magnetic field sensor in a channel with a first electrical conductor supported on the substrate positioned at least in part along the channel gap and in direct contact with at least some surface of the magnetic field sensor ands a second electrical conductor supported on the substrate positioned at least in part along the channel gap in a region thereof adjacent to, but separated from, the magnetic field sensor.
摘要翻译：一种基于铁磁薄膜的磁场检测系统，其具有在通道中支撑磁场传感器的基板，所述基板支撑在所述基板上，所述第一电导体至少部分地沿着所述通道间隙位于所述基板上，并且与所述第一电导体的至少一些表面直接接触磁场传感器和支撑在基板上的第二电导体，该第二电导体至少部分地沿着与磁场传感器相邻但与之隔离的区域中的沟槽间隙定位。

6. 发明授权

US06875621B2 Magnetizable bead detector 有权
标题翻译：磁珠检测仪
公开(公告)号：US06875621B2
公开(公告)日：2005-04-05
申请号：US09799429
申请日：2001-03-05
申请人： Mark C. Tondra
发明人： Mark C. Tondra
IPC分类号： G01N27/72 , G01R33/09 , G01N33/553
CPC分类号： G01N27/745 , G01R33/09 , G01R33/1269 , Y10T29/49002 , Y10T29/49007 , Y10T29/4902
摘要： A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding to the selected molecular species. The magnetic field sensor can be substantially covered by an electrical insulating layer having a recess therein adjacent to the sensor in which the binding molecule layer is provided. An electrical interconnection conductor can be supported on the substrate at least in part between the sensor and the substrate, and is electrically connected to the sensor. The magnetic field sensor can be provided in a bridge circuit, and can be formed by a number of interconnected individual sensors. A polymeric channel and reservoir structure base is provided for the system.
摘要翻译：一种用于检测选定分子种类存在的基于铁磁薄膜的磁场检测系统。负载在基板上的磁场传感器具有位于其能够选择性地结合所选择的分子种类的一侧的结合分子层。磁场传感器可以基本上被电绝缘层覆盖，该电绝缘层在其中设置有结合分子层的传感器附近具有凹部。电互连导体可以至少部分地在传感器和基板之间被支撑在基板上，并且电连接到传感器。磁场传感器可以设置在桥式电路中，并且可以由多个互连的单独的传感器形成。为系统提供聚合物通道和储存器结构基底。

7. 发明授权

US06743639B1 Magnetizable bead detector 有权
标题翻译：磁珠检测仪
公开(公告)号：US06743639B1
公开(公告)日：2004-06-01
申请号：US09687791
申请日：2000-10-13
申请人： Mark C. Tondra , John M. Anderson
发明人： Mark C. Tondra , John M. Anderson
IPC分类号： G01N33553
CPC分类号： G01N27/745 , G01R33/09
摘要： A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding to the selected molecular species. The magnetic field sensor can be substantially covered by an electrical insulating layer having a recess therein adjacent to the sensor in which the binding molecule layer is provided. An electrical interconnection conductor can be supported on the substrate at least in part between the sensor and the substrate, and is electrically connected to the sensor. The magnetic field sensor can be provided in a bridge circuit, and can be formed by a number of interconnected individual sensors.
摘要翻译：一种用于检测选定分子种类存在的基于铁磁薄膜的磁场检测系统。负载在基板上的磁场传感器具有位于其能够选择性地结合所选择的分子种类的一侧的结合分子层。磁场传感器可以基本上被电绝缘层覆盖，该电绝缘层在其中设置有结合分子层的传感器附近具有凹部。电互连导体可以至少部分地在传感器和基板之间被支撑在基板上，并且电连接到传感器。磁场传感器可以设置在桥式电路中，并且可以由多个互连的单独的传感器形成。

8. 发明授权

US07446524B2 Method for detecting magnetic particles in a fluid using thin-film magnetic field sensor 有权
标题翻译：使用薄膜磁场传感器检测流体中的磁性颗粒的方法
公开(公告)号：US07446524B2
公开(公告)日：2008-11-04
申请号：US11809254
申请日：2007-05-31
申请人： Mark C. Tondra
发明人： Mark C. Tondra
IPC分类号： G01N27/74 , G01R33/12
CPC分类号： G01N27/745 , G01R33/09 , G01R33/1269 , Y10T29/49002 , Y10T29/49007 , Y10T29/4902
摘要： A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding to the selected molecular species held on a magnetic particle. The magnetic field sensor can be substantially covered by an electrical insulating layer having a recess therein adjacent to the sensor in which the binding molecule layer is provided. A thin-film channel structure to the sensor is supported on the substrate that can be accompanied by a reservoir structure, and an electrical interconnection conductor is supported on the substrate at least in part between the sensor and the substrate, and is electrically connected to the sensor. The magnetic field sensor can be provided in a bridge circuit, and can be formed by a number of interconnected individual sensors.
摘要翻译：一种用于检测选定分子种类存在的基于铁磁薄膜的磁场检测系统。支撑在基板上的磁场传感器具有位于其一侧上的结合分子层，其能够选择性地结合保持在磁性颗粒上的所选择的分子种类。磁场传感器可以基本上被电绝缘层覆盖，该电绝缘层在其中设置有结合分子层的传感器附近具有凹部。传感器的薄膜通道结构被支撑在基板上，该基板可以伴随着储存器结构，并且电互连导体至少部分地被支撑在基板上，并且与传感器和基板之间电连接传感器。磁场传感器可以设置在桥式电路中，并且可以由多个互连的单独的传感器形成。

9. 发明授权

US06462541B1 Uniform sense condition magnetic field sensor using differential magnetoresistance 有权
标题翻译：使用差分磁阻的均匀感应条件磁场传感器
公开(公告)号：US06462541B1
公开(公告)日：2002-10-08
申请号：US09439892
申请日：1999-11-12
申请人： Dexin Wang , Mark C. Tondra , James M. Daughton
发明人： Dexin Wang , Mark C. Tondra , James M. Daughton
IPC分类号： G01R3302
CPC分类号： B82Y25/00 , G01R33/093
摘要： A ferromagnetic thin-film based sensing arrangement having a plurality of magnetic field sensors on a substrate each having an intermediate layer of a nonmagnetic material with two major surfaces on opposite sides thereof with one of a pair of magnetically permeable films each of a magnetoresistive, anisotropic ferromagnetic material correspondingly positioned thereon with first and second oriented sensors therein respectively having a selected and a reversing magnetization orientation structure provided with one of said pair of permeable films thereof for orienting its magnetization in a selected direction absent an externally applied magnetic field in at least partly opposing directions. Alternatively, these magnetizations of the films can be oriented in the same direction but with the other film member of the pair provided adjacent a coupling layer that antiferromagnetically couples thereto a further ferromagnetic layer on an opposite side thereof of a lesser thickness for one sensor and a greater thickness for the other. Such a sensing arrangement can be formed by providing a succession of material layers on a substrate with one or more coupling layers for antiferromagnetically coupling ferromagnetic layers on opposite sides thereof including a permeable film. Selective removal of the succession follows to provide unequal numbers of coupling layers for the two kinds of sensors or unequal thicknesses of corresponding ferromagnetic layers corresponding to the coupling layer and the providing of a pinning layer for both kinds of sensors which are thereafter separated by further material removal.
摘要翻译：一种基于铁磁薄膜的感测装置，其具有在基板上的多个磁场传感器，每个磁场传感器具有非磁性材料的中间层，在其相对侧上具有两个主表面，其中一个磁导膜与磁阻，各向异性相应地设置在其上的第一和第二定向传感器的铁磁材料分别具有选定的和反向的磁化取向结构，所述磁性取向结构设置有所述一对可渗透膜中的一个，用于在选定的方向上使其磁化方向定向，而不存在外部施加的磁场，至少部分相反的方向或者，膜的这些磁化可以在相同的方向上取向，但是一对中的另一个膜构件邻近耦合层设置，其反铁磁耦合到一个传感器的较小厚度的相对侧上的另一个铁磁层，并且更大的厚度为另一个。这样的感测装置可以通过在衬底上提供一系列材料层而形成，该层具有一个或多个耦合层，用于在其相对侧上反铁磁耦合铁磁层，包括可渗透膜。继续的选择性删除是为两种传感器提供不相等数量的耦合层，或者对应于耦合层的相应铁磁层的不等厚度以及为这两种传感器提供钉扎层，然后由另外的材料分离删除。

10. 再颁专利

USRE44878E1 Current switched magnetoresistive memory cell 有权
标题翻译：电流开关磁阻存储单元
公开(公告)号：USRE44878E1
公开(公告)日：2014-05-06
申请号：US13617738
申请日：2012-09-14
申请人： James M. Daughton , Arthur V. Pohm , Mark C. Tondra
发明人： James M. Daughton , Arthur V. Pohm , Mark C. Tondra
IPC分类号： H01L21/02
CPC分类号： B82Y25/00 , G11C11/161 , H01F1/408 , H01F10/1936 , H01F10/3268 , H01F10/3272
摘要： A ferromagnetic thin-film based digital memory cell with a memory film of an anisotropic ferromagnetic material and with a source layer positioned on one side thereof so that a majority of conduction electrons passing therefrom have a selected spin orientation to be capable of reorienting the magnetization of the film. A disruption layer is positioned on the other side of the memory film so that conduction electrons spins passing therefrom are substantially random in orientation. The magnitude of currents needed to operate the cell can be reduced using coincident thermal pulses to raise the cell temperature.
摘要翻译：一种基于铁磁性薄膜的数字存储单元，其具有各向异性铁磁材料的记忆膜并且其一侧位于其一侧，使得其中通过的大部分传导电子具有选定的自旋取向以能够重新定向磁化这个电影。破坏层位于存储膜的另一侧，使得通过的导电电子在取向上基本上是随机的。可以使用重合的热脉冲来降低操作电池所需的电流的大小，以提高电池温度。

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