专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2013212228A Hanger 有权
标题翻译：衣架
公开(公告)号：JP2013212228A
公开(公告)日：2013-10-17
申请号：JP2012083343
申请日：2012-03-31
申请人： Mai Ito , 真衣伊藤
发明人： ITO MAI
IPC分类号： D06F57/00 , A47G25/34
摘要： PROBLEM TO BE SOLVED: To provide a hanger preventing hangers from being entangled with each other when being housed, and hard to fall down.SOLUTION: A hanger 1 comprises: a hook 2 provided in the upper portion of the hanger 1, having an upwardly curved shape, and provided so as to from a portion of a triangular frame of the hanger 1; shoulders 3 and 4 provided to as to be opened downward in a double-leaf shape; and a horizontal lever 5 which laterally bridges both lower ends of the shoulder levers 3 and 4. The hook 2, the shoulder levers 3 and 4 and the horizontal lever 5 form the triangular frame. Portions of the shoulder levers 3 and 4 are provided with opening/closing parts 6 for opening and closing inwardly and outwardly, respectively. The opening/closing parts 6 are pivotally supported on the horizontal lever 5 side, and the hook 2 is provided with an antislip inside thereof.
摘要翻译：要解决的问题：提供一种衣架，防止衣架在收纳时彼此缠结，并且难以塌落。解决方案：衣架1包括：设置在衣架1的上部的钩2，具有向上并且设置成从吊架1的三角形框架的一部分; 肩3和4被设置为以双叶形状向下打开; 以及横向安装肩部杆3和4的两个下端的水平杆5.钩2，肩杆3和4以及水平杆5形成三角形框架。肩杆3和4的部分设有开/关部分6，用于分别向内和向外打开和关闭。开/关部6枢转地支撑在水平杆5侧，钩2在其内部设有防滑。

2. 发明申请

US20140194290A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL 有权
标题翻译：熔化杂环化合物及其用于害虫控制
公开(公告)号：US20140194290A1
公开(公告)日：2014-07-10
申请号：US14234717
申请日：2012-08-03
申请人： Masaki Takahashi , Takamasa Tanabe , Mai Ito , Yoshihiko Nokura , Atsushi Iwata
发明人： Masaki Takahashi , Takamasa Tanabe , Mai Ito , Yoshihiko Nokura , Atsushi Iwata
IPC分类号： A01N43/90 , A01N43/52 , A01N43/76
CPC分类号： C07D213/81 , A01N43/52 , A01N43/76 , A01N43/78 , A01N43/90 , C07D401/04 , C07D413/04 , C07D417/04 , C07D471/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.
摘要翻译：提供对由式（1）表示的害虫具有优异的防治效果的化合物：其中，A1表示-NR7-等，A2表示氮原子等，A3表示氮原子等，R1 表示任选被一个或多个选自X等元素的基团取代的C 1 -C 6链烃基，R 2，R 3和R 4相同或不同，各自表示任选被一个或多个取代基取代的C 1 -C 6链烃基更多的卤原子等，R 5和R 6相同或不同，并且各自表示任选被一个或多个选自X等的一个或多个原子或基团取代的C 1 -C 6链烃基，R 7表示C 1 -C 6链烃任选被一个或多个选自组W等的原子或基团取代的基团，n表示0,1或2或其N-氧化物。

3. 发明授权

US07935336B2 Highly functional enzyme having α-galactosidase activity 有权
标题翻译：具有α-半乳糖苷酶活性的高功能酶
公开(公告)号：US07935336B2
公开(公告)日：2011-05-03
申请号：US12084982
申请日：2006-11-17
申请人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
发明人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
IPC分类号： A61K38/47 , A61K38/43 , C12N9/40 , C12N15/00 , C12P21/06 , C12P19/34 , C07H21/04
CPC分类号： C12N9/2465 , A61K38/00 , C12N9/2402 , C12Y302/01022 , C12Y302/01049
摘要： The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having α-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired α-galactosidase activity by changing the structure of the active site of wild-type human α-N-acetylgalactosaminidase.
摘要翻译：本发明提供作为法布里病的酶替代疗法的酶，不具有过敏性副作用的具有α-半乳糖苷酶活性的蛋白质在血液中显示高稳定性，并且可以容易地加入到受影响器官的细胞。本发明的蛋白质是通过改变野生型人α-N-乙酰半乳糖胺酶活性位点的结构而获得α-半乳糖苷酶活性的蛋白质。

4. 发明申请

US20140018373A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF 有权
标题翻译：熔化杂环化合物和用于其控制的病虫害
公开(公告)号：US20140018373A1
公开(公告)日：2014-01-16
申请号：US13996697
申请日：2011-12-22
申请人： Hayato Takyo , Masaki Takahashi , Takamasa Tanabe , Yoshihiko Nokura , Mai Ito , Atsushi Iwata
发明人： Hayato Takyo , Masaki Takahashi , Takamasa Tanabe , Yoshihiko Nokura , Mai Ito , Atsushi Iwata
IPC分类号： A01N43/90 , A01N43/76 , A01N43/78 , A01N43/52
CPC分类号： C07D513/04 , A01N43/52 , A01N43/76 , A01N43/78 , A01N43/90 , A01N47/02 , A01N47/06 , C07D233/64 , C07D235/18 , C07D263/57 , C07D277/66 , C07D277/68 , C07D471/04 , C07D498/04
摘要： A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.
摘要翻译：式（1）的稠合杂环化合物：其中A1表示-NR8-等; A2表示氮原子等; A3表示氮原子等; R1表示任选具有一个或多个选自X组的原子或基团的C 1 -C 6链烃基等; R2，R3，R4和R5相同或不同，独立地表示任选具有一个或多个卤素原子的C 1 -C 6链烃基等; R6和R7相同或不同，独立地表示任选具有一个或多个选自X组的原子或基团的C 1 -C 6链烃基等; R8表示任选具有一个或多个选自W组的原子或基团的C 1 -C 6链烃基等; n表示0,1或2.该化合物具有优异的防治害虫的活性。

5. 发明授权

US09018134B2 Fused heterocyclic compound and use thereof for pest control 有权
标题翻译：熔融杂环化合物及其用于害虫防治的用途
公开(公告)号：US09018134B2
公开(公告)日：2015-04-28
申请号：US14234717
申请日：2012-08-03
申请人： Masaki Takahashi , Takamasa Tanabe , Mai Ito , Yoshihiko Nokura , Atsushi Iwata
发明人： Masaki Takahashi , Takamasa Tanabe , Mai Ito , Yoshihiko Nokura , Atsushi Iwata
IPC分类号： A01N43/90 , A01N43/52 , A01N43/76 , A01N43/78 , C07D471/04 , C07D495/04 , C07D498/04
CPC分类号： C07D213/81 , A01N43/52 , A01N43/76 , A01N43/78 , A01N43/90 , C07D401/04 , C07D413/04 , C07D417/04 , C07D471/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： There is provided a compound having an excellent controlling effect on pests represented by the formula (1): wherein, A1 represents —NR7—, etc., A2 represents a nitrogen atom, etc., A3 represents a nitrogen atom, etc., R1 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R2, R3 and R4 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more halogen atoms, etc., R5 and R6 are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group X, etc., R7 represents a C1-C6 chain hydrocarbon group optionally substituted by one or more atoms or groups selected from Group W, etc., n represents 0, 1 or 2, or an N-oxide thereof.
摘要翻译：提供对由式（1）表示的害虫具有优异的防治效果的化合物：其中，A1表示-NR7-等，A2表示氮原子等，A3表示氮原子等，R1 表示任选被一个或多个选自X等元素的基团取代的C 1 -C 6链烃基，R 2，R 3和R 4相同或不同，各自表示任选被一个或多个取代基取代的C 1 -C 6链烃基更多的卤原子等，R 5和R 6相同或不同，并且各自表示任选被一个或多个选自X等的一个或多个原子或基团取代的C 1 -C 6链烃基，R 7表示C 1 -C 6链烃任选被一个或多个选自组W等的原子或基团取代的基团，n表示0,1或2或其N-氧化物。

6. 发明授权

US08323640B2 Highly functional enzyme having α-galactosidase activity 有权
标题翻译：具有α-半乳糖苷酶活性的高功能酶
公开(公告)号：US08323640B2
公开(公告)日：2012-12-04
申请号：US13052632
申请日：2011-03-21
申请人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
发明人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
IPC分类号： A61K38/43 , C12N9/40 , C12N15/00 , C12P21/06 , C12P19/34 , C07H21/04 , C07K1/00
CPC分类号： C12N9/2465 , A61K38/00 , C12N9/2402 , C12Y302/01022 , C12Y302/01049
摘要： The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having α-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired α-galactosidase activity by changing the structure of the active site of wild-type human α-N-acetylgalactosaminidase.
摘要翻译：本发明提供作为法布里病的酶替代疗法的酶，不具有过敏性副作用的具有α-半乳糖苷酶活性的蛋白质在血液中显示高稳定性，并且可以容易地加入到受影响器官的细胞。本发明的蛋白质是通过改变野生型人α-N-乙酰半乳糖胺酶活性位点的结构而获得α-半乳糖苷酶活性的蛋白质。

7. 发明申请

US20110171198A1 HIGHLY FUNCTIONAL ENZYME HAVING ALPHA-GALACTOSIDASE ACTIVITY 有权
标题翻译：具有ALPHA-GALACTOSIDASE活性的高功能酶
公开(公告)号：US20110171198A1
公开(公告)日：2011-07-14
申请号：US13052632
申请日：2011-03-21
申请人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
发明人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
IPC分类号： C12N9/40 , C12N15/56 , C12N15/85 , C12N5/10 , C12P21/02 , A61K38/47 , A61P3/00
CPC分类号： C12N9/2465 , A61K38/00 , C12N9/2402 , C12Y302/01022 , C12Y302/01049
摘要： The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having α-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired α-galactosidase activity by changing the structure of the active site of wild-type human α-N-acetylgalactosaminidase.
摘要翻译：本发明提供作为法布里病的酶替代疗法的酶，不具有过敏性副作用的具有α-半乳糖苷酶活性的蛋白质在血液中显示高稳定性，并且可以容易地加入到受影响器官的细胞。本发明的蛋白质是通过改变野生型人α-N-乙酰半乳糖胺酶活性位点的结构而获得α-半乳糖苷酶活性的蛋白质。

8. 发明申请

US20100166728A1 Novel Highly Functional Enzyme Having Modified Substrate-Specificity 有权
标题翻译：具有修饰底物特异性的新型高功能酶
公开(公告)号：US20100166728A1
公开(公告)日：2010-07-01
申请号：US12084982
申请日：2006-11-17
申请人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
发明人： Hitoshi Sakuraba , Youichi Tajima , Mai Ito , Seiichi Aikawa , Fumiko Aikawa
IPC分类号： A61K38/47 , A61P3/00 , A61P13/12 , A61P27/02 , A61P25/00 , A61P9/04 , A61P17/00 , A61P29/00 , C12N9/40 , C12N15/56 , C12N15/63 , C12N5/00
CPC分类号： C12N9/2465 , A61K38/00 , C12N9/2402 , C12Y302/01022 , C12Y302/01049
摘要： The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having α-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired α-galactosidase activity by changing the structure of the active site of wild-type human α-N-acetylgalactosaminidase.
摘要翻译：本发明提供作为法布里病的酶替代疗法的酶，不具有过敏性副作用的具有α-半乳糖苷酶活性的蛋白质在血液中显示高稳定性，并且可以容易地加入到受影响器官的细胞。本发明的蛋白质是通过改变野生型人α-N-乙酰半乳糖胺酶活性位点的结构而获得α-半乳糖苷酶活性的蛋白质。

9. 发明授权

US08853238B2 Fused heterocyclic compound and use thereof for pest control 有权
标题翻译：熔融杂环化合物及其用于害虫防治的用途
公开(公告)号：US08853238B2
公开(公告)日：2014-10-07
申请号：US13996697
申请日：2011-12-22
申请人： Hayato Takyo , Masaki Takahashi , Takamasa Tanabe , Yoshihiko Nokura , Mai Ito , Atsushi Iwata
发明人： Hayato Takyo , Masaki Takahashi , Takamasa Tanabe , Yoshihiko Nokura , Mai Ito , Atsushi Iwata
IPC分类号： C07D513/02 , C07D515/02 , A61K31/44
CPC分类号： C07D513/04 , A01N43/52 , A01N43/76 , A01N43/78 , A01N43/90 , A01N47/02 , A01N47/06 , C07D233/64 , C07D235/18 , C07D263/57 , C07D277/66 , C07D277/68 , C07D471/04 , C07D498/04
摘要： A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.
摘要翻译：式（1）的稠合杂环化合物：其中A1表示-NR8-等; A2表示氮原子等; A3表示氮原子等; R1表示任选具有一个或多个选自X组的原子或基团的C 1 -C 6链烃基等; R2，R3，R4和R5相同或不同，独立地表示任选具有一个或多个卤素原子的C 1 -C 6链烃基等; R6和R7相同或不同，独立地表示任选具有一个或多个选自X组的原子或基团的C 1 -C 6链烃基等; R8表示任选具有一个或多个选自W组的原子或基团的C 1 -C 6链烃基等; n表示0,1或2.该化合物具有优异的防治害虫的活性。

10. 发明申请

US20090297592A1 Lipid Vesicle Composition 审中-公开
标题翻译：脂质囊泡组成
公开(公告)号：US20090297592A1
公开(公告)日：2009-12-03
申请号：US11920094
申请日：2006-05-11
申请人： Hitoshi Sakuraba , Youichi Tajima , Ikuo Kawashima , Mai Ito , Shinji Takeoka , Katsuji Ohta , Manabu Ito , Atsushi Mizuno
发明人： Hitoshi Sakuraba , Youichi Tajima , Ikuo Kawashima , Mai Ito , Shinji Takeoka , Katsuji Ohta , Manabu Ito , Atsushi Mizuno
IPC分类号： A61K9/127 , A61K38/47 , A61P3/00
CPC分类号： A61K9/1272 , A61K9/0019 , A61K9/1271 , A61K38/47
摘要： It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like.This problem is solved by a lipid vesicle composition wherein vesicles composed of a lipid bilayer membrane are encapsulating an enzyme, the composition being capable of retaining stably the activity of the enzyme even outside the stable pH range of the enzyme.
摘要翻译：本发明的目的是提供一种在血液中的稳定性（血液停留）和转移至靶器官（靶向特性）优异的酶制剂，可以有效地用于酶替代疗法等。这个问题是通过脂质囊泡组合物来解决的，其中由脂质双层膜组成的囊泡正在封装酶，该组合物能够稳定地保持酶的活性甚至在酶的稳定pH范围之外。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式