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1. 发明公开

EP0668764A1 METHODS FOR IDENTIFYING AND USING LOW/NON-ADDICTIVE OPIOID ANALGESICS 失效
标题翻译：方法鉴定和使用阿片类镇痛药具有低或无依赖可能性。
公开(公告)号：EP0668764A1
公开(公告)日：1995-08-30
申请号：EP93921686.0
申请日：1993-09-17
申请人： QIN, Bo-yi , SHEN, Ke-fei , GONG, Xiong-qi , CRAIN, Stanley, M. , MAO, Huang , WANG, Chang, Yi
发明人： QIN, Bo-yi , SHEN, Ke-fei , GONG, Xiong-qi , CRAIN, Stanley, M. , MAO, Huang , WANG, Chang, Yi
IPC分类号： G01N33 , A61K31 , C07D489
CPC分类号： G01N33/9486 , A61K31/00 , A61K31/137 , A61K31/485 , G01N33/94 , G01N2500/10 , A61K2300/00
摘要： The present invention relates to a method of using a bioassay consisting of an electrophysiological method and a cell culture system of dorsal-root ganglion (DRG) neurons to screen and identify opioids with a high potential for use as 'low- or non-addictive' analgesics. Another aspect of the invention relates to a specific group of opioid alkaloids and analogues thereof identified by the bioassay of the invention for the unique ability to activate only inhibitory, but not excitatory, opioid receptor function, for use as low- or non-addictive analgesics. Another aspect of the invention relates to the specific use of etorphine or dihydroetorphine of the opioid alkaloid family as low- or non-addictive analgesics and for the treatment of opioid addiction. The present invention also relates to the preparation of dihydroetorphine hydrochloride (7α-[1-(R)-hydroxy-1-methylbutyl]-6,14-endo-ethano-tetrahydrooripavine hydrochloride) and a pharmaceutical composition comprising the compound as an active ingredient in the form of a pharmaceutically acceptable salt.

2. 发明专利

DE202015101079U1 Demontageeinrichtung für die Riemenscheibe 未知
公开(公告)号：DE202015101079U1
公开(公告)日：2015-03-11
申请号：DE202015101079
申请日：2015-03-05
申请人： CHUAN MAO HUANG
IPC分类号： B25B27/073 , B25B27/02
摘要： Die Demontageeinrichtung für die Riemenscheibe umfasst mindestens: Eine Führungsstange, die in die axiale Richtung durch ein Gewindeloch steckt, das zum Verschrauben einer Drückstange dient. Zwei Greifarmen, die jeweils mit einem nicht selbst rotierbaren Führungsloch vorgesehen sind, das sich entlang der Führungsstange in der axialen Richtung zueinander gleiten können. Des Weiteren umfasst der Greifarm noch eine erste Führungsschiene und einen Klemmteil. Die erste Führungsschiene kreuzt sich in der axialen Richtung senkrecht zur axialen Richtung des Führungslochs. Zwei Greifelemente, die jeweils mit einer der ersten Führungsschiene entsprechenden zweiten Führungsschiene vorgesehen sind, mit derer Hilfe das Greifelement abmontierbar am entsprechenden Greifarm angebracht werden kann. Das Greifelement ist außerdem noch mit einem dem ersten Klemmteil passenden entsprechenden zweiten Klemmteil vorgesehen, wobei der erste und der zweite Klemmteil sich miteinander fixieren. Die Greifelemente sind jeweils mit zueinander stehenden Krallen vorgesehen. Die beiden Greifarmen treiben die Kralle des jeweiligen Greifelements an, um den Rand der Riemenscheibe zu greifen und ermöglicht somit die Drückstange die Riemenscheibe durch die Schraubbewegung abzumontieren.

3. 发明专利

CA2145207A1 METHODS FOR IDENTIFYING AND USING LOW/NON-ADDICTIVE OPIOID ANALGESICS 未知
公开(公告)号：CA2145207A1
公开(公告)日：1994-03-22
申请号：CA2145207
申请日：1993-09-17
申请人： QIN BO YI , GONG XIONG QI , CRAIN STANLEY M , MAO HUANG , YI WANG CHANG , SHEN KE FEI
发明人： QIN BO-YI , SHEN KE-FEI , GONG XIONG-QI , CRAIN STANLEY M , MAO HUANG , YI WANG CHANG
IPC分类号： G01N33/53 , A61K31/00 , A61K31/485 , C07D489/00 , G01N33/94 , C12Q1/02 , C07D489/12
摘要： The present invention relates to a method of using a bioassay consisting of an electrophysiological method and a cell culture system of dorsal-root ganglion (DRG) neurons to screen and identify opioids with a high potential for use as "low- or nonaddictive" analgesics. Another aspect of the invention relates to a specific group of opioid alkaloids and analogues thereof identified by the bioassay of the invention for the unique ability to activate only inhibitory, but not excitatory, opioid receptor function, for use as low- or non-addictive analgesics. Another aspect of the invention relates to the specific use of etorphine or dihydroetorphine of the opioid alkaloid family as low- or non-addictive analgesics and for the treatment of opioid addiction. The present invention also relates to the preparation of dihydroetorphine hydrochloride (7a-¢1-(R)-hydroxy-1-methylbutyl!-6,14-endo-ethano-tetrahydrooripavine hydrochloride) and a pharmaceutical composition comprising the compound as an active ingredient in the form of a pharmaceutically acceptable salt.

4. 发明申请

WO1994006426A1 METHODS FOR IDENTIFYING AND USING LOW/NON-ADDICTIVE OPIOID ANALGESICS 审中-公开
标题翻译：识别和使用低/非阿片类药物的方法
公开(公告)号：WO1994006426A1
公开(公告)日：1994-03-31
申请号：PCT/US1993008869
申请日：1993-09-17
申请人： QIN, Bo-yi , SHEN, Ke-fei , GONG, Xiong-qi , CRAIN, Stanley, M. , MAO, Huang , WANG, Chang, Yi
IPC分类号： A61K31/46
CPC分类号： G01N33/9486 , A61K31/00 , A61K31/137 , A61K31/485 , G01N33/94 , G01N2500/10 , A61K2300/00
摘要： The present invention relates to a method of using a bioassay consisting of an electrophysiological method and a cell culture system of dorsal-root ganglion (DRG) neurons to screen and identify opioids with a high potential for use as "low- or non-addictive" analgesics. Another aspect of the invention relates to a specific group of opioid alkaloids and analogues thereof identified by the bioassay of the invention for the unique ability to activate only inhibitory, but not excitatory, opioid receptor function, for use as low- or non-addictive analgesics. Another aspect of the invention relates to the specific use of etorphine or dihydroetorphine of the opioid alkaloid family as low- or non-addictive analgesics and for the treatment of opioid addiction. The present invention also relates to the preparation of dihydroetorphine hydrochloride (7(alpha)-(1-(R)-hydroxy-1-methylbutyl)-6,14-endo-ethano-tetrahydrooripavine hydrochloride) and a pharmaceutical composition comprising the compound as an active ingredient in the form of a pharmaceutically acceptable salt.
摘要翻译：本发明涉及使用由电生理学方法和背根神经节（DRG）神经元的细胞培养系统组成的生物测定法来筛选和鉴定具有高潜力用作“低或非成瘾性”的阿片样物质的方法，镇痛药。本发明的另一方面涉及通过本发明的生物测定鉴定的特定组的阿片样物质生物碱及其类似物，其特征在于仅使用抑制性但不兴奋性的阿片受体功能仅用于作为低或非成瘾性止痛剂。本发明的另一方面涉及阿片样物质生物碱家族的吗啡或二氢阿托啡作为低或非成瘾止痛剂和用于治疗阿片样物质成瘾的具体用途。本发明还涉及二氢阿托啡盐酸盐（7（α） - （1-（R） - 羟基-1-甲基丁基）-6,14-内 - 乙酸 - 四氢奥帕匹酸盐酸盐的制备）和包含该化合物呈药学上可接受的盐形式的活性成分。

5. 发明申请

US20160236336A1 Removal device for belt pulley 审中-公开
标题翻译：皮带轮拆卸装置
公开(公告)号：US20160236336A1
公开(公告)日：2016-08-18
申请号：US14622947
申请日：2015-02-16
申请人： Chuan Mao HUANG
发明人： Chuan Mao HUANG
IPC分类号： B25B27/02
CPC分类号： B25B27/023 , B25B27/062
摘要： A removal device for a belt pulley contains: a guiding rod, two clamping members, and two paws. The guiding rod includes a screwing hole defined on a central position thereof to screw with a push rod. The two clamping members slide along the guiding rod, and each clamping member includes a guide orifice for inserting the guiding rod, a first guide rail, and a first engaging portion, wherein a first direction of the first guide rail is perpendicular to a second direction of the screwing hole. Each paw includes a second guide rail for matching with the first guide rail, such that each of the two paws is connected with or removed from each of the two clamping members, wherein the second guide rail has a second engaging portion for cooperating with the first engaging portion.
摘要翻译：用于皮带轮的去除装置包括：导杆，两个夹紧构件和两个爪。导杆包括限定在其中心位置上的螺丝孔，以与推杆一起旋拧。两个夹紧构件沿着导杆滑动，并且每个夹紧构件包括用于插入导向杆的导向孔，第一导轨和第一接合部分，其中第一导轨的第一方向垂直于第二方向的螺丝孔。每个爪包括用于与第一导轨匹配的第二导轨，使得两个爪中的每一个与两个夹紧构件中的每一个连接或移除，其中第二导轨具有用于与第一导轨配合的第二接合部分接合部。

6. 发明授权

US09352466B2 Robot positioning system for semiconductor tools 有权
标题翻译：半导体工具机器人定位系统
公开(公告)号：US09352466B2
公开(公告)日：2016-05-31
申请号：US13486019
申请日：2012-06-01
申请人： Wen-Huang Liao , Hsien-Mao Huang
发明人： Wen-Huang Liao , Hsien-Mao Huang
IPC分类号： B25J9/16 , H01L21/67 , H01L21/68 , G06K9/32
CPC分类号： B25J9/1697 , B25J9/1692 , G05B2219/39008 , G05B2219/39046 , G05B2219/45031 , G06K9/3208 , H01L21/67259 , H01L21/681
摘要： A system and method for adjusting the position and orientation of a feed arm associated with a wafer handling robot. In one embodiment, the system includes a positioning plate detachably carried by the feed arm and insertable therewith into a wafer carrier. The positioning plate includes graphic alignment indicia. An alignment apparatus is provided configured for insertion into wafer-holding slots in the wafer carrier. The apparatus includes at least one digital image sensor. With the positioning plate and alignment apparatus located in the wafer carrier, an image of the alignment indicia is displayed on a video monitor by the image sensor for comparison to a reference mark superimposed on the monitor for determining the relative position and orientation of the feed arm with respect to the wafer carrier. Some embodiments of the apparatus further include a distance detection device to measure the distance to the plate.
摘要翻译：一种用于调节与晶片处理机器人相关联的进给臂的位置和方向的系统和方法。在一个实施例中，系统包括可由进给臂可拆卸地承载并可插入到晶片载体中的定位板。定位板包括图形对齐标记。提供配置用于插入晶片载体中的晶片保持槽的对准装置。该装置包括至少一个数字图像传感器。利用位于晶片载体中的定位板和对准装置，通过图像传感器在视频监视器上显示对准标记的图像，以与叠加在监视器上的参考标记进行比较，以确定进给臂的相对位置和方向相对于晶片载体。该装置的一些实施例还包括测量到板的距离的距离检测装置。

7. 发明授权

US09035195B2 Circuit board having tie bar buried therein and method of fabricating the same 有权
标题翻译：埋设有连杆的电路板及其制造方法
公开(公告)号：US09035195B2
公开(公告)日：2015-05-19
申请号：US13674919
申请日：2012-11-12
申请人： Hsin-Mao Huang , Chun-Huang Yu
发明人： Hsin-Mao Huang , Chun-Huang Yu
IPC分类号： H05K1/11 , H05K3/24 , H05K1/02
CPC分类号： H05K3/242 , H05K1/0298 , H05K1/112 , H05K1/113 , H05K1/117 , H05K3/244 , H05K2201/0338 , H05K2203/0228
摘要： Provided is a circuit board having a tie bar buried therein. The circuit board includes a dielectric stack, at least a first tie bar, at least a first gold finger and at least a first microvia. The dielectric stack includes a first dielectric layer and a second dielectric layer. The first dielectric layer is located on the second dielectric layer. The dielectric stack includes a wireline region and a gold finger region. The first tie bar is buried in the gold finger region between the first dielectric layer and the second dielectric layer. The at least a first gold finger is located in the gold finger region on the first dielectric layer. The first microvia is located in the gold finger region in the first dielectric layer, and electrically connects the first gold finger to the first tie bar.
摘要翻译：提供一种具有埋入其中的连接杆的电路板。电路板包括电介质叠层，至少第一连接条，至少第一金指和至少第一微孔。电介质堆叠包括第一电介质层和第二电介质层。第一电介质层位于第二电介质层上。电介质堆叠包括有线区域和金指区域。第一连杆被埋在第一介电层和第二介电层之间的金指区域中。至少第一金手指位于第一介电层上的金指区域中。第一微孔位于第一电介质层中的金指区域中，并且将第一金手指电连接到第一连接杆。

8. 发明申请

US20140049482A1 TOUCH DETECTION STRUCTURE AND TOUCH DISPLAY DEVICE USING SAME 审中-公开
标题翻译：使用相同的触摸检测结构和触摸显示设备
公开(公告)号：US20140049482A1
公开(公告)日：2014-02-20
申请号：US13589677
申请日：2012-08-20
申请人： Chiu-Mao Huang
发明人： Chiu-Mao Huang
IPC分类号： G06F3/041
CPC分类号： G06F3/0421
摘要： A touch detection structure and a touch display device using same are disclosed. The touch detection structure includes a frame, a plurality of transmitters, and a plurality of receivers. A printed circuit layer is directly formed on one surface of the frame by way of mechanical processing to electrically connect to the transmitters and the receivers. With the printed circuit layer being directly formed on the frame of the touch detection structure, the touch display device using such touch detection structure can save the costs for using and manufacturing circuit boards and has reduced overall thickness to enable convenient assembling thereof.
摘要翻译：公开了触摸检测结构和使用它的触摸显示装置。触摸检测结构包括帧，多个发射机以及多个接收机。通过机械处理将印刷电路层直接形成在框架的一个表面上，以电连接到发射器和接收器。由于印刷电路层直接形成在触摸检测结构的框架上，所以使用这样的触摸检测结构的触摸显示装置可以节省使用和制造电路板的成本，并且减小了总厚度以便于其组装。

9. 发明申请

US20140048677A1 BEARING CUP BASE AND FAN FRAME ASSEMBLY USING SAME 审中-公开
标题翻译：使用相同的轴承座和风扇框架组件
公开(公告)号：US20140048677A1
公开(公告)日：2014-02-20
申请号：US13589541
申请日：2012-08-20
申请人： Chiu-Mao Huang
发明人： Chiu-Mao Huang
IPC分类号： F16C35/02 , F16M1/04
CPC分类号： H05K7/20172 , F04D25/062 , F04D29/646
摘要： A bearing cup base and a fan frame assembly provided with same are disclosed. The bearing cup base includes a base body having a first side, a bearing cup perpendicularly forward extended from the first side of the base body, and a printed circuit layer formed on the first side. By directly forming the printed circuit layer on the bearing cup base, a fan using the bearing cup base can be manufactured at largely reduced cost and can have a further reduced overall height.
摘要翻译：公开了一种轴承座底座和一个具有该轴承座的风扇框架组件。所述轴承座底座包括具有第一侧的基体，从所述基体的第一侧垂直向前延伸的轴承杯，以及形成在所述第一侧上的印刷电路层。通过在轴承座底座上直接形成印刷电路层，可以以大大降低的成本制造使用轴承杯座的风扇，并且可以进一步降低整体高度。

10. 发明申请

US20120085608A1 Luggage Inflatable Structure 审中-公开
标题翻译：行李充气结构
公开(公告)号：US20120085608A1
公开(公告)日：2012-04-12
申请号：US12902276
申请日：2010-10-12
申请人： Jung-Mao HUANG
发明人： Jung-Mao HUANG
IPC分类号： A45C13/00
CPC分类号： A45C13/021
摘要： A luggage inflatable structure includes a sleeve fixedly mounted in the housing of a luggage, an air bag received in a bottom lining and the periphery of the housing of the luggage, and a pull rod having a piston located on the bottom end thereof and movable up and down in the sleeve for pumping air into the air bag so that storage items are held firmly in position when the air bag is inflated, avoiding storage item damage or noises during carrying or delivery of the luggage.
摘要翻译：行李箱充气结构包括固定地安装在行李箱的壳体中的套筒，容纳在底部衬里中的气囊和行李箱的外围，以及具有位于其底端上的活塞的拉杆并且在套筒中向下抽吸空气进入气囊，使得当气囊膨胀时，储存物品牢固地保持在适当位置，避免在行李运送或运送过程中存储物品损坏或噪音。

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