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1. 发明申请

US20140275208A1 Compositions and Methods to Control Insect Pests 有权
标题翻译：防治虫害的组成和方法
公开(公告)号：US20140275208A1
公开(公告)日：2014-09-18
申请号：US13831230
申请日：2013-03-14
申请人： XU HU , JAMES PRESNAIL , NINA Richtman , SCOTT DIEHN , MICHELLE HARNACK , LISA PROCYK
发明人： XU HU , JAMES PRESNAIL , NINA Richtman , SCOTT DIEHN , MICHELLE HARNACK , LISA PROCYK
IPC分类号： A01N57/16 , C12N15/113
CPC分类号： C12N15/113 , A01N37/46 , A01N63/02 , C12N15/8218 , C12N15/8286 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or active variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiments, the pest is D. virgifera virgifera, D. barberi, D. virgifera zeae, D. speciosa, D. speciosa, or D. undecimpunctata howardi. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译：提供了使用沉积元件的方法和组合物，当由有害生物摄取的诸如鞘翅目植物病虫害（Diaprotica plant pest）的害虫时，会降低害虫中靶序列的表达。在具体实施方案中，靶序列的表达降低控制有害生物，因此方法和组合物能够限制对植物的损害。本发明提供了本文所公开的任何一个（但不包括正向和反向引物）或其活性变体及其片段或其互补序列的任何一种或多种靶基因，其中一个或多个目标害虫中更多的序列控制害虫（即具有杀虫活性）。进一步提供的是沉积元件，当受害虫摄入时，降低靶多肽的水平，从而控制害虫。在具体实施方案中，害虫是D. virgifera virgifera，D.barberi，D. virgifera zeae，D. speciosa，D. speciosa或D. undecimpunctata howardi。还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其它宿主细胞。

2. 发明申请

US20100221238A1 PROTEIN MIXTURES FOR MAIZE INSECT CONTROL 有权
标题翻译：蛋白质混合物用于玉米控制
公开(公告)号：US20100221238A1
公开(公告)日：2010-09-02
申请号：US12691841
申请日：2010-01-22
申请人： JOHN L. FLEXNER , DEIRDRE M. KAPKA-KITZMAN , LISA PROCYK , BRUCE STANLEY , JIANZHOU ZHAO
发明人： JOHN L. FLEXNER , DEIRDRE M. KAPKA-KITZMAN , LISA PROCYK , BRUCE STANLEY , JIANZHOU ZHAO
IPC分类号： A01N63/00 , A01H5/00 , A01N43/88 , A01N43/647 , A01N43/36 , A01N43/56 , A01N57/00 , A01P3/00 , A01P5/00 , A01P7/02 , A01P7/04 , A01P13/00 , A01P15/00
CPC分类号： C12N15/8286 , A01N63/02 , C12N15/8274 , Y02A40/162 , A01N2300/00
摘要： Embodiments of the present invention relate to insecticidal Bacillus thuringiensis Cry1 and Cry2 polypeptides. Methods for using the polypeptides and nucleic acids of embodiments of the invention to synergistically enhance resistance of plants to insect predation are encompassed in embodiments of the present invention.
摘要翻译：本发明的实施方案涉及杀虫的苏云金芽孢杆菌Cry1和Cry2多肽。使用本发明实施方案的多肽和核酸协同增强植物对昆虫捕食的抗性的方法包括在本发明的实施方案中。

3. 发明申请

US20130236870A1 Online Interactive Practice System 审中-公开
标题翻译：在线互动练习系统
公开(公告)号：US20130236870A1
公开(公告)日：2013-09-12
申请号：US13416564
申请日：2012-03-09
申请人： Richard WASSERMAN , Richard LONGENECKER , Deborah MATTIN , Jamie CAROTHERS , Lisa PROCYK , Sherry ANDREWS
发明人： Richard WASSERMAN , Richard LONGENECKER , Deborah MATTIN , Jamie CAROTHERS , Lisa PROCYK , Sherry ANDREWS
IPC分类号： G09B23/28
CPC分类号： G09B5/06 , G09B5/08
摘要： An online, interactive practice system is provided, which allows users to practice skills and to learn about desired subjects using interactive, multimedia practice modules (tools) relating to desired subjects. The system includes a computer system in communication with a plurality of remote user devices via a network, a plurality of multimedia practice modules stored in a database of the computer system each including a lesson relating to a healthcare-related topic and allowing a user to practice a skill relating to the lesson, and a common directory structure for aggregating each of the plurality of multimedia practice modules. The system transmits a software module corresponding to a selected multimedia practice module to at least one of the plurality of remote user devices, for execution thereby to generate a virtual practice environment where the user can view a lesson and virtually practice a skill relating to the lesson.
摘要翻译：提供了一个在线交互式练习系统，它允许用户使用与所需主题相关的交互式多媒体练习模块（工具）来练习技能并学习所需科目。该系统包括经由网络与多个远程用户设备通信的计算机系统，存储在计算机系统的数据库中的多个多媒体练习模块，每个包括与医疗保健相关的主题相关的课程，并允许用户练习与课程相关的技能，以及用于聚合多个多媒体练习模块中的每一个的公共目录结构。系统将与所选择的多媒体练习模块相对应的软件模块发送到多个远程用户设备中的至少一个，以便执行，从而生成虚拟练习环境，其中用户可以观看课程并虚拟地练习与课程相关的技能。

4. 发明授权

US08729336B2 Protein mixtures for maize insect control 有权
标题翻译：用于玉米昆虫控制的蛋白质混合物
公开(公告)号：US08729336B2
公开(公告)日：2014-05-20
申请号：US12691841
申请日：2010-01-22
申请人： John L. Flexner , Deirdre M. Kapka-Kitzman , Lisa Procyk , Bruce Stanley , Jianzhou Zhao
发明人： John L. Flexner , Deirdre M. Kapka-Kitzman , Lisa Procyk , Bruce Stanley , Jianzhou Zhao
IPC分类号： A01H5/00 , C07K14/325 , A01N37/18 , C12N15/32 , C12N15/82
CPC分类号： C12N15/8286 , A01N63/02 , C12N15/8274 , Y02A40/162 , A01N2300/00
摘要： Embodiments of the present invention relate to insecticidal Bacillus thuringiensis Cry1 and Cry2 polypeptides. Methods for using the polypeptides and nucleic acids of embodiments of the invention to synergistically enhance resistance of plants to insect predation are encompassed in embodiments of the present invention.
摘要翻译：本发明的实施方案涉及杀虫苏云金芽孢杆菌Cry1和Cry2多肽。使用本发明实施方案的多肽和核酸协同增强植物对昆虫捕食的抗性的方法包括在本发明的实施方案中。

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