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1. 发明申请

US20090118131A1 Genetic comparisons between grandparents and grandchildren 有权
标题翻译：祖父母和孙子之间的遗传比较
公开(公告)号：US20090118131A1
公开(公告)日：2009-05-07
申请号：US12288026
申请日：2008-10-15
申请人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
IPC分类号： C40B30/00 , C40B60/12
CPC分类号： G06F19/26 , G06F19/14 , G06F19/18 , G06F19/22
摘要： Displaying a comparison of genotypic information between relatives is disclosed, including receiving an indication that a first individual is a grandparent, receiving an indication that a second individual is a grandchild of the first individual, comparing the genotypic information of the first individual and the second individual and calculating a similarity score, and displaying an indication of the similarity score graphically using colors.
摘要翻译：公开了显示亲属之间的基因型信息的比较，包括接收第一个体是祖父母的指示，接收第二个体是第一个体的孙子的指示，比较第一个体和第二个体的基因型信息以及计算相似性得分，并使用颜色以图形方式显示相似性得分的指示。

2. 发明授权

US09864835B2 Genetic comparisons between grandparents and grandchildren 有权
公开(公告)号：US09864835B2
公开(公告)日：2018-01-09
申请号：US12288026
申请日：2008-10-15
申请人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
IPC分类号： G06F19/20 , G06F19/26 , G06F19/14 , G06F19/18 , G06F19/22
CPC分类号： G06F19/26 , G06F19/14 , G06F19/18 , G06F19/22
摘要： Displaying a comparison of genotypic information between relatives is disclosed, including receiving an indication that a first individual is a grandparent, receiving an indication that a second individual is a grandchild of the first individual, comparing the genotypic information of the first individual and the second individual and calculating a similarity score, and displaying an indication of the similarity score graphically using colors.

3. 发明授权

US09336177B2 Genome sharing 有权
公开(公告)号：US09336177B2
公开(公告)日：2016-05-10
申请号：US12288014
申请日：2008-10-14
申请人： Brian Lee Hawthorne , Oleksiy Khomenko , Jeffrey Mellen , Marcela Miyazawa , Michael Polcari , Jack Tihon , Alexander Wong , Anne Wojcicki , Linda Avey
发明人： Brian Lee Hawthorne , Oleksiy Khomenko , Jeffrey Mellen , Marcela Miyazawa , Michael Polcari , Jack Tihon , Alexander Wong , Anne Wojcicki , Linda Avey
IPC分类号： G06F7/00 , G06F15/16 , G06F17/30
CPC分类号： H04L63/101 , G06F15/16 , G06F17/30867 , G06F17/3089 , G06F19/18 , H04L67/306
摘要： Sharing data is disclosed. In some cases, sharing data includes receiving a request to share data from a first account to a second account, receiving an indication of a plurality of first account profiles associated with the first account to share with the second account, and establishing sharing from the plurality of first account profiles to the second account, wherein sharing comprises the second account having read access to a subset of nonpublic data associated with the plurality of first account profiles.

4. 发明授权

US08589437B1 De-identification and sharing of genetic data 有权
标题翻译：遗传数据的识别和共享
公开(公告)号：US08589437B1
公开(公告)日：2013-11-19
申请号：US12288017
申请日：2008-10-14
申请人： Oleksiy Khomenko , Alexander Wong , Anne Wojcicki , Linda Avey
发明人： Oleksiy Khomenko , Alexander Wong , Anne Wojcicki , Linda Avey
IPC分类号： G06F17/30
CPC分类号： G06F19/28
摘要： A system for separating identifying data from personal data is disclosed. The system includes: a first set of stored data comprising a plurality of identifying data structures containing identifying data; a second set of stored data comprising a plurality of personal data structures containing personal data; a set of mapping data comprising a plurality of mappings, wherein each mapping is between an identifying data structure and a personal data structure; and an application configured to receive mapping data associated with a mapping, determine a mapping associated with the mapping data, and obtain a personal data structure based on the mapping. The set of mapping data is logically separate from the first set of stored data, the second set of stored data, and the application.
摘要翻译：公开了一种用于从识别数据与个人数据分离的系统。该系统包括：包含识别数据的多个识别数据结构的第一组存储数据; 包括包含个人数据的多个个人数据结构的第二组存储数据; 一组包括多个映射的映射数据，其中每个映射在识别数据结构和个人数据结构之间; 以及被配置为接收与映射相关联的映射数据的应用，确定与映射数据相关联的映射，以及基于映射获得个人数据结构。该组映射数据在逻辑上与第一组存储数据，第二组存储数据和应用程序分开。

5. 发明授权

US08463554B2 Finding relatives in a database 有权
标题翻译：在数据库中找到亲属
公开(公告)号：US08463554B2
公开(公告)日：2013-06-11
申请号：US12644791
申请日：2009-12-22
申请人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
发明人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
IPC分类号： G06F7/00
CPC分类号： G06F19/14 , G06F17/30522 , G06F17/30867 , G06F19/22 , G06F19/28 , G06N5/048
摘要： Determining relative relationship includes receiving recombinable deoxyribonucleic acid (DNA) information of a first user and recombinable DNA information of a second user, determining, based at least in part on the recombinable DNA information of the first user and recombinable DNA information of the second user, a predicted degree of relationship between the first user and the second user, and in the event that the expected degree of relationship between the first user and the second user at least meets the threshold, notifying at least the first user about a relative relationship with the second user.
摘要翻译：确定相对关系包括接收第一用户的可重复脱氧核糖核酸（DNA）信息和第二用户的可重复DNA信息，至少部分基于第一用户的可重复DNA信息和第二用户的可重复DNA信息，第一用户和第二用户之间的预测关系程度，并且在第一用户和第二用户之间的预期关系程度至少满足阈值的情况下，至少通知第一用户关于与第第二个用户

6. 发明授权

US08543339B2 Gamete donor selection based on genetic calculations 有权
标题翻译：基于遗传计算的配子供体选择
公开(公告)号：US08543339B2
公开(公告)日：2013-09-24
申请号：US12592950
申请日：2009-12-04
申请人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
发明人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
IPC分类号： G06F7/00
CPC分类号： G06F19/28 , G06F19/18
摘要： Gamete donor selection includes receiving a specification including a phenotype of interest, receiving a genotype of a recipient and a plurality of genotypes of a respective plurality of donors, determining statistical information pertaining to the phenotype of interest based at least in part on different pairings of the genotype of the recipient and a genotype of a donor in the plurality of donors, and identifying a preferred donor among the plurality of donors, based at least in part on the statistical information determined.
摘要翻译：配子供体选择包括接收包括感兴趣的表型，接受接受者的基因型和相应的多个供体的多个基因型的规范，至少部分地基于不同的配对，确定与感兴趣的表型有关的统计信息至少部分地基于所确定的统计信息，接收者的基因型和多个供体中的供体的基因型以及多个供体中的优选给体。

7. 发明申请

US20100223281A1 FINDING RELATIVES IN A DATABASE 有权
标题翻译：在数据库中查找相关性
公开(公告)号：US20100223281A1
公开(公告)日：2010-09-02
申请号：US12644791
申请日：2009-12-22
申请人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
发明人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
IPC分类号： G06F17/30
CPC分类号： G06F19/14 , G06F17/30522 , G06F17/30867 , G06F19/22 , G06F19/28 , G06N5/048
摘要： Determining relative relationship includes receiving recombinable deoxyribonucleic acid (DNA) information of a first user and recombinable DNA information of a second user, determining, based at least in part on the recombinable DNA information of the first user and recombinable DNA information of the second user, a predicted degree of relationship between the first user and the second user, and in the event that the expected degree of relationship between the first user and the second user at least meets the threshold, notifying at least the first user about a relative relationship with the second user.
摘要翻译：确定相对关系包括接收第一用户的可重复脱氧核糖核酸（DNA）信息和第二用户的可重复DNA信息，至少部分基于第一用户的可重复DNA信息和第二用户的可重复DNA信息，第一用户和第二用户之间的预测关系程度，并且在第一用户和第二用户之间的预期关系程度至少满足阈值的情况下，至少通知第一用户关于与第第二个用户

8. 发明申请

US20090112871A1 Genome sharing 有权
标题翻译：基因组共享
公开(公告)号：US20090112871A1
公开(公告)日：2009-04-30
申请号：US12288014
申请日：2008-10-14
申请人： Brian Lee Hawthorne , Oleksiy Khomenko , Jeffrey Mellen , Marcela Miyazawa , Michael Polcari , Jack Tihon , Alexander Wong , Anne Wojcicki , Linda Avey
发明人： Brian Lee Hawthorne , Oleksiy Khomenko , Jeffrey Mellen , Marcela Miyazawa , Michael Polcari , Jack Tihon , Alexander Wong , Anne Wojcicki , Linda Avey
IPC分类号： G06F17/30
CPC分类号： H04L63/101 , G06F15/16 , G06F17/30867 , G06F17/3089 , G06F19/18 , H04L67/306
摘要： Sharing data is disclosed. In some cases, sharing data includes receiving a request to share data from a first account to a second account, receiving an indication of a plurality of first account profiles associated with the first account to share with the second account, and establishing sharing from the plurality of first account profiles to the second account, wherein sharing comprises the second account having read access to a subset of nonpublic data associated with the plurality of first account profiles.
摘要翻译：公开共享数据。在一些情况下，共享数据包括接收从第一帐户共享数据到第二帐户的请求，接收与第一帐户相关联的多个第一账户配置文件的指示以与第二账户共享，以及从多个账户建立共享的第一帐户简档到第二帐户，其中共享包括具有对与多个第一帐户简档相关联的非公开数据的子集的读取访问的第二帐户。

9. 发明授权

US08510057B1 Summarizing an aggregate contribution to a characteristic for an individual 有权
标题翻译：总结对个人特征的贡献
公开(公告)号：US08510057B1
公开(公告)日：2013-08-13
申请号：US12151977
申请日：2008-05-08
申请人： Linda Avey , Andro Rene Hsu , Oleksiy Khomenko , John Michael Macpherson , Joanna Louise Mountain , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Andro Rene Hsu , Oleksiy Khomenko , John Michael Macpherson , Joanna Louise Mountain , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
IPC分类号： G06F7/00
CPC分类号： G06F19/24 , G06F19/18
摘要： Summarizing an aggregate contribution to a characteristic for an individual is disclosed, including determining the characteristic to be evaluated, identifying one or more markers associated with the characteristic, retrieving the measurement of the individual for each of the one or more markers from a database of individuals' markers, retrieving a statistical factor that measures the association between the marker associated with the characteristic and the characteristic for each of the one or more markers from the marker database, and determining the aggregate contribution based at least in part on the retrieved statistical factors.
摘要翻译：公开了对个体的特征的总体贡献的总结，包括确定要评估的特征，识别与特征相关联的一个或多个标记，从个体数据库中检索针对一个或多个标记中的每一个的个体的测量标记，检索测量与特征相关联的标记与来自标记数据库的一个或多个标记中的每一个的特征的关联的统计因子，以及至少部分地基于所检索的统计因素来确定总贡献。

10. 发明申请

US20100145981A1 Gamete donor selection based on genetic calculations 有权
标题翻译：基于遗传计算的配子供体选择
公开(公告)号：US20100145981A1
公开(公告)日：2010-06-10
申请号：US12592950
申请日：2009-12-04
申请人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
发明人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
IPC分类号： G06F17/30
CPC分类号： G06F19/28 , G06F19/18
摘要： Gamete donor selection includes receiving a specification including a phenotype of interest, receiving a genotype of a recipient and a plurality of genotypes of a respective plurality of donors, determining statistical information pertaining to the phenotype of interest based at least in part on different pairings of the genotype of the recipient and a genotype of a donor in the plurality of donors, and identifying a preferred donor among the plurality of donors, based at least in part on the statistical information determined.
摘要翻译：配子供体选择包括接收包括感兴趣的表型，接受接受者的基因型和相应的多个供体的多个基因型的规范，至少部分地基于不同的配对，确定与感兴趣的表型有关的统计信息至少部分地基于所确定的统计信息，接收者的基因型和多个供体中的供体的基因型以及多个供体中的优选给体。

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