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1. 发明申请

WO2007076721A2 A DISPLAY AND PRESENTATION METHOD AND A DISPLAY SYSTEM AND PRESENTATION APPARATUS FOR 3D VIRTUAL IMAGE 审中-公开
标题翻译：一种显示和呈现方法以及用于3D虚拟图像的显示系统和呈现设备
公开(公告)号：WO2007076721A2
公开(公告)日：2007-07-12
申请号：PCT/CN2006003820
申请日：2006-12-31
申请人： TENCENT TECH SHENZHEN CO LTD , GU SIBIN , XIA LIN , JIA YAN , WANG HUIXING , FAN XIAO , LI LI , LIANG ZHU
发明人： GU SIBIN , XIA LIN , JIA YAN , WANG HUIXING , FAN XIAO , LI LI , LIANG ZHU
IPC分类号： G06T17/00 , G06T13/40 , H04L12/58
CPC分类号： H04L51/04 , G06T13/40
摘要： A display method for 3D virtual image is provided. It includes the following steps: the 3D virtual image configuration file and 3D classification data are obtained locally; the 3D classification data is displayed according to the 3D virtual image configuration file. A display system for 3D virtual image is also provided. It includes a 3D virtual image background server, which comprises a 3D virtual image identifier-setting unit and a 3D virtual image database, and a terminal device with an instant communication client end, which comprises a 3D virtual image judging module, a storage module for configuration file, a local specified entry base and a 3D display engine. A presentation method for 3D virtual image is also provided. It includes the following steps: the human model is divided into several models comprising at least arm model and lower leg model; and when the clothing model is displayed relating to the arm model and/or lower leg model, and the models overlap with each other, hides the clothing model corresponding to the arm model and/or lower leg model. A presentation apparutus is also provided.
摘要翻译：提供了3D虚拟图像的显示方法。它包括以下步骤：在本地获得3D虚拟图像配置文件和3D分类数据; 根据3D虚拟图像配置文件显示3D分类数据。还提供了用于3D虚拟图像的显示系统。包括3D虚拟图像后台服务器，其包括3D虚拟图像标识设置单元和3D虚拟图像数据库，以及具有即时通信客户端的终端设备，其包括3D虚拟图像判断模块，存储模块配置文件，本地指定的条目库和3D显示引擎。还提供了3D虚拟图像的呈现方法。它包括以下步骤：将人体模型分为至少包含手臂模型和小腿模型的几个模型; 并且当显示与臂模型和/或小腿模型有关的服装模型并且模型彼此重叠时，隐藏与臂模型和/或小腿模型相对应的服装模型。还提供演示apparutus。

2. 发明授权

US09518029B2 Certain chemical entities, compositions, and methods 有权
标题翻译：某些化学实体，组合物和方法
公开(公告)号：US09518029B2
公开(公告)日：2016-12-13
申请号：US14344709
申请日：2012-09-14
申请人： Xiangping Qian , Yong-Liang Zhu
发明人： Xiangping Qian , Yong-Liang Zhu
IPC分类号： A61K31/498 , A61K31/5377 , A61K45/06 , C07D241/42 , C07D401/04 , C07D401/12 , C07D403/04
CPC分类号： C07D241/42 , A61K31/498 , A61K31/5377 , A61K45/06 , A61P35/00 , C07D241/44 , C07D401/04 , C07D401/12 , C07D403/04
摘要： Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.
摘要翻译：描述了基于喹喔啉作为激酶抑制剂的化学实体。具体描述了含有抑制Braf突变体激酶活性的二芳基酰胺或二芳基脲亚结构的式I的喹喔啉衍生物，含有抑制剂化合物的药物组合物和治疗癌症的方法包括施用有效量的Braf抑制剂化合物。

3. 发明授权

US08999957B2 Heterocyclic compounds as ERK inhibitors 有权
标题翻译：杂环化合物作为ERK抑制剂
公开(公告)号：US08999957B2
公开(公告)日：2015-04-07
申请号：US13703250
申请日：2011-06-22
申请人： Yongqi Deng , Liang Zhu , Gerald W. Shipps, Jr. , Sie-Mun Lo , Binyuan Sun , Xiaohua Huang , Corey Bienstock , Alan B. Cooper , Xiaolei Gao , Xin Yao , Hugh Y. Zhu , Joseph M. Kelly , Sobhana Babu Boga , Abdul-Basit Alhassan , Jayaram R. Tagat , Umar Faruk Mansoor , Kevin J. Wilson , Brendan M. O'Boyle , Matthew Hersh Daniels , Adam Schell , Phieng Siliphaivanh , Christian Fischer
发明人： Yongqi Deng , Liang Zhu , Gerald W. Shipps, Jr. , Sie-Mun Lo , Binyuan Sun , Xiaohua Huang , Corey Bienstock , Alan B. Cooper , Xiaolei Gao , Xin Yao , Hugh Y. Zhu , Joseph M. Kelly , Sobhana Babu Boga , Abdul-Basit Alhassan , Jayaram R. Tagat , Umar Faruk Mansoor , Kevin J. Wilson , Brendan M. O'Boyle , Matthew Hersh Daniels , Adam Schell , Phieng Siliphaivanh , Christian Fischer
IPC分类号： C07D401/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D401/14 , C07D405/14 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K31/695 , A61K45/06 , C07F7/18
CPC分类号： C07D401/14 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K31/695 , A61K45/06 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07F7/1804
摘要： The present invention provides a compound of the Formula I: (Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
摘要翻译：本发明提供了式I化合物：（式I应在此插入）或其药学上可接受的盐，溶剂化物或酯，其中R，R 1，R 2和R 3如本文所定义。这些化合物是ERK抑制剂。还公开了包含上述化合物的药物组合物和使用其治疗癌症的方法。

4. 发明授权

US08979614B2 Deburring machine 有权
标题翻译：去毛刺机
公开(公告)号：US08979614B2
公开(公告)日：2015-03-17
申请号：US13480713
申请日：2012-05-25
申请人： Ming-Lu Yang , Liang Zhu , Zhong-Wei Yang
发明人： Ming-Lu Yang , Liang Zhu , Zhong-Wei Yang
IPC分类号： B24B9/00
CPC分类号： B24B9/005
摘要： A deburring machine for removing burrs from workpieces includes a framework, a deburring mechanism and a transport mechanism. The deburring mechanism mounted on the framework, includes deburring units positioned on the framework. The transport mechanism is positioned on the framework adjacent to the deburring units. The transport mechanism includes a base, multi-station rotating plate and a first driver. The base is positioned on the framework. The multi-station rotating plate is rotatably positioned on the base. The first driver is positioned on the framework and connects with the base. The first driver is capable of driving the multi-station rotating plate to transport the workpieces to the plurality of deburring units, the plurality of deburring units are capable of removing the burrs of the workpieces.
摘要翻译：用于从工件去除毛刺的去毛刺机器包括框架，去毛刺机构和输送机构。安装在框架上的去毛刺机构包括位于框架上的去毛刺单元。运输机构位于与去毛刺单元相邻的框架上。输送机构包括基座，多工位旋转板和第一驱动器。基座位于框架上。多工位旋转板可旋转地定位在基座上。第一个驱动器位于框架上并与基座连接。第一驱动器能够驱动多工位旋转板将工件运送到多个去毛刺单元，多个去毛刺单元能够去除工件的毛刺。

5. 发明授权

US08691977B2 Certain chemical entities, compositions, and methods 有权
标题翻译：某些化学实体，组合物和方法
公开(公告)号：US08691977B2
公开(公告)日：2014-04-08
申请号：US13215120
申请日：2011-08-22
申请人： Xiangping Qian , Yong-Liang Zhu
发明人： Xiangping Qian , Yong-Liang Zhu
IPC分类号： C07J53/00 , C07D207/00 , C07D241/04 , C07D295/00 , A01N35/00 , A01N33/02 , A61K31/535 , A61K31/40
CPC分类号： C07J63/008
摘要： Chemical entities which are triterpenoid derivatives, pharmaceutical compositions and methods of treatment of inflammatory, neurodegenerative, neoplastic and autoimmune diseases are described.
摘要翻译：描述了三萜衍生物的化学实体，药物组合物和治疗炎性，神经变性，肿瘤和自身免疫性疾病的方法。

6. 发明授权

US08546404B2 Compounds that are ERK inhibitors 有权
标题翻译： ERK抑制剂的化合物
公开(公告)号：US08546404B2
公开(公告)日：2013-10-01
申请号：US11810282
申请日：2007-06-05
申请人： Alan B. Cooper , Yongqi Deng , Gerald W. Shipps, Jr. , Neng-Yang Shih , Hugh Y. Zhu , Robert Sun , Joseph M. Kelly , Ronald J. Doll , Yang Nan , Tong Wang , Jagdish A. Desai , James J-S Wang , Youhao Dong , Vincent S. Madison , Li Xiao , Alan W. Hruza , M. Arshad Siddiqui , Ahmed A. Samatar , Sunil Paliwal , Hon-Chung Tsui , Azim Alan Celebi , Yiji Wu , Sobhana Babu Boga , Abdul-Basit Alhassan , Xiaolei Gao , Liang Zhu , Mehul Patel
发明人： Alan B. Cooper , Yongqi Deng , Gerald W. Shipps, Jr. , Neng-Yang Shih , Hugh Y. Zhu , Robert Sun , Joseph M. Kelly , Ronald J. Doll , Yang Nan , Tong Wang , Jagdish A. Desai , James J-S Wang , Youhao Dong , Vincent S. Madison , Li Xiao , Alan W. Hruza , M. Arshad Siddiqui , Ahmed A. Samatar , Sunil Paliwal , Hon-Chung Tsui , Azim Alan Celebi , Yiji Wu , Sobhana Babu Boga , Abdul-Basit Alhassan , Xiaolei Gao , Liang Zhu , Mehul Patel
IPC分类号： A01N43/54 , C07D239/42 , C07D401/04
CPC分类号： C07D231/56 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/14
摘要： Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
摘要翻译：公开了式1.0的ERK抑制剂及其药学上可接受的盐，酯和溶剂化物。 Q是可以具有桥或稠合环的哌啶或哌嗪环。哌啶环可以在环中具有双键。所有其他取代基如本文所定义。还公开了使用式1.0化合物治疗癌症的方法。

7. 发明申请

US20130109283A1 DEBURRING MACHINE 有权
标题翻译：脱机机
公开(公告)号：US20130109283A1
公开(公告)日：2013-05-02
申请号：US13480713
申请日：2012-05-25
申请人： MING-LU YANG , LIANG ZHU , ZHONG-WEI YANG
发明人： MING-LU YANG , LIANG ZHU , ZHONG-WEI YANG
IPC分类号： B24B47/10
CPC分类号： B24B9/005
摘要： A deburring machine for removing burrs from workpieces includes a framework, a deburring mechanism and a transport mechanism. The deburring mechanism mounted on the framework, includes deburring units positioned on the framework. The transport mechanism is positioned on the framework adjacent to the deburring units. The transport mechanism includes a base, multi-station rotating plate and a first driver. The base is positioned on the framework. The multi-station rotating plate is rotatably positioned on the base. The first driver is positioned on the framework and connects with the base. The first driver is capable of driving the multi-station rotating plate to transport the workpieces to the plurality of deburring units, the plurality of deburring units are capable of removing the burrs of the workpieces.
摘要翻译：用于从工件去除毛刺的去毛刺机器包括框架，去毛刺机构和输送机构。安装在框架上的去毛刺机构包括位于框架上的去毛刺单元。运输机构位于与去毛刺单元相邻的框架上。输送机构包括基座，多工位旋转板和第一驱动器。基座位于框架上。多工位旋转板可旋转地定位在基座上。第一个驱动器位于框架上并与基座连接。第一驱动器能够驱动多工位旋转板将工件运送到多个去毛刺单元，多个去毛刺单元能够去除工件的毛刺。

8. 发明申请

US20130040945A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS 有权
标题翻译：某些化学实验，组合物和方法
公开(公告)号：US20130040945A1
公开(公告)日：2013-02-14
申请号：US13571973
申请日：2012-08-10
申请人： Xiangping Qian , Yong-Liang Zhu
发明人： Xiangping Qian , Yong-Liang Zhu
IPC分类号： A61K31/365 , C07D405/12 , A61P35/00 , C07D413/12 , A61K31/5377 , C07D307/33 , A61K31/4525
CPC分类号： C07D307/33 , C07D405/12
摘要： Chemical entities that are arctigenin derivatives, pharmaceutical compositions and methods of treatment of cancer are described.
摘要翻译：描述了作为癌基因的衍生物，药物组合物和癌症治疗方法的化学实体。

9. 发明授权

US08114982B2 Multi-microRNA methods and compositions 失效
标题翻译：多微RNA方法和组合物
公开(公告)号：US08114982B2
公开(公告)日：2012-02-14
申请号：US12312616
申请日：2007-11-28
申请人： Liang Zhu , Daqian Sun
发明人： Liang Zhu , Daqian Sun
IPC分类号： C07H21/04
CPC分类号： C12N15/111 , C12N15/113 , C12N2310/111 , C12N2310/14 , C12N2320/10
摘要： Provided are DNAs comprising a polynucleotide that encodes at least a first modified miR-30 precursor and a second modified miR-30 precursor. Also provided are vectors comprising the the DNAs, where the vector can replicate in a host cell. Additionally, specific lentiviral vectors comprising the above-described DNA are provided, as are methods of inhibiting expression of a target gene in a eukaryotic cell.
摘要翻译：提供了包含编码至少第一修饰的miR-30前体和第二修饰的miR-30前体的多核苷酸的DNA。还提供了包含DNA的载体，其中载体可以在宿主细胞中复制。此外，提供了包含上述DNA的特定慢病毒载体，以及抑制靶基因在真核细胞中的表达的方法。

10. 发明授权

US07399776B2 Polyamine compounds for treating chemokine receptor mediated diseases 失效
标题翻译：用于治疗趋化因子受体介导的疾病的多胺化合物
公开(公告)号：US07399776B2
公开(公告)日：2008-07-15
申请号：US10814058
申请日：2004-03-30
申请人： Kak-Shan Shia , Gholam Hossein Hakimelahi , Jia-Liang Zhu , Chi-Feng Yen , Ying-Huey Huang , Yibin Xiang , Hua-Chien Chen , Ching-Cheng Wang
发明人： Kak-Shan Shia , Gholam Hossein Hakimelahi , Jia-Liang Zhu , Chi-Feng Yen , Ying-Huey Huang , Yibin Xiang , Hua-Chien Chen , Ching-Cheng Wang
IPC分类号： A61K31/40 , A61K31/18 , A61K31/165 , A61K31/15 , A61K31/195
CPC分类号： C07D207/335 , A61K31/135 , A61K31/15 , A61K31/165 , A61K31/195 , A61K31/44 , A61K31/445 , C07C211/27 , C07C211/29 , C07C211/30 , C07D209/08 , C07D213/38 , C07D213/42 , C07D213/74 , C07D235/14 , C07D257/02 , C07D333/18 , C07D401/14 , C07D409/14 , C07D471/04
摘要： This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of the following formula. Each variable in this formula is defined in the specification.
摘要翻译：本发明涉及一种治疗炎性疾病或免疫疾病，发育或退行性疾病或组织损伤的方法。该方法包括向有需要的受试者施用有效量的一种或多种下列化合物。该公式中的每个变量在规范中定义。

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