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1. 发明申请

US20060095021A1 Introduction of agent with medical device 审中-公开
标题翻译：介绍代理与医疗器材
公开(公告)号：US20060095021A1
公开(公告)日：2006-05-04
申请号：US10979774
申请日：2004-11-02
申请人： Jesus Casas-Bejar , Laura Christoferson , Adam Blakstvedt
发明人： Jesus Casas-Bejar , Laura Christoferson , Adam Blakstvedt
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61L29/16 , A61L2300/404 , A61L2300/45 , A61M25/00 , A61M25/10 , A61M39/0208 , A61M2025/0057 , A61M2025/105
摘要： The disclosure is directed to apparatus and techniques that deliver an antibiotic or loosening agent to a patient by diffusion. An element of the medical device deployed proximate to the living cells includes a diffusible material, which comprises a lumen. An agent introduced into the lumen diffuses through the diffusible material to the living cells or tissues. The invention can be applied to medical devices that are placed partially inside a patient, as well as those that are fully implanted. Some embodiments support moving the internal element of a medical device proximate to targeted cells, such as a tumor, and administering an antibiotic agent to the targeted cells by diffusion. The disclosure also encompasses a testing system that helps test and develop apparatus and techniques for delivering an agent by diffusion.
摘要翻译：本公开涉及通过扩散将抗生素或松动剂递送给患者的装置和技术。靠近活细胞部署的医疗装置的元件包括可扩散材料，其包括管腔。引入内腔的药剂通过可扩散材料扩散到活细胞或组织。本发明可以应用于部分放置在患者体内的医疗装置以及完全植入的医疗装置。一些实施例支持将医疗装置的内部元件移动到靠近靶细胞（例如肿瘤），并通过扩散将靶向细胞施用抗生素。本公开还包括一种测试系统，其帮助测试和开发用于通过扩散递送代理的设备和技术。

2. 发明申请

US20060095020A1 Introduction of agent with medical device 审中-公开
标题翻译：介绍代理与医疗器材
公开(公告)号：US20060095020A1
公开(公告)日：2006-05-04
申请号：US11263098
申请日：2005-10-31
申请人： Jesus Casas , Laura Christoferson , Adam Blakstvedt
发明人： Jesus Casas , Laura Christoferson , Adam Blakstvedt
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61L29/16 , A61L2300/404 , A61L2300/45 , A61M25/00 , A61M25/10 , A61M39/0208 , A61M2025/0057 , A61M2025/105
摘要： The disclosure is directed to apparatus and techniques that deliver an active agent, such as an antibiotic age nt or loosening agent to a patient by diffusion. An element of the medical device deployed proximate to the cells or host tissue includes a diffusible material, which comprises a lumen. An agent introduced into the lumen diffuses through the diffusible material to the cells or host tissue or tissues. The invention can be applied to medical devices that are placed partially inside a patient, as well as those that are fully implanted. Some embodiments support moving the internal element of a medical device proximate to targeted cells, such as a tumor, and administering an active agent to the targeted cells by diffusion. The disclosure also encompasses a testing system that helps test and develop apparatus and techniques for delivering an agent by diffusion.
摘要翻译：本公开涉及通过扩散将活性剂（例如抗生素年龄或松动剂）递送给患者的装置和技术。靠近细胞或宿主组织部署的医疗装置的元件包括可扩散材料，其包括管腔。引入内腔的药剂通过可扩散材料扩散到细胞或宿主组织或组织。本发明可以应用于部分放置在患者体内的医疗装置以及完全植入的医疗装置。一些实施例支持将医疗装置的内部元件移动到靠近靶细胞（例如肿瘤）并且通过扩散将活性剂施用于靶细胞。本公开还包括一种测试系统，其帮助测试和开发用于通过扩散递送代理的设备和技术。

3. 发明授权

US08512731B2 Antimicrobial coatings for medical devices and methods for making and using them 有权
标题翻译：医疗器械的抗微生物涂层及其制造和使用方法
公开(公告)号：US08512731B2
公开(公告)日：2013-08-20
申请号：US11983930
申请日：2007-11-13
申请人： Zhongping Yang , Eunjoo Jin , Laura Christoferson , Rajiv Shah
发明人： Zhongping Yang , Eunjoo Jin , Laura Christoferson , Rajiv Shah
IPC分类号： A61K38/43 , A61K38/44
CPC分类号： A61L27/34 , A61L27/54 , A61L2300/11 , A61L2300/208
摘要： Embodiments of the invention provide methods for using compositions to inhibit microbial growth on a surface of a medical device having the composition applied thereto, to medical devices having the composition applied to a surface thereof and to methods for using the compositions to coat medical devices.
摘要翻译：本发明的实施方案提供了使用组合物抑制其施用组合物的医疗装置的表面上的微生物生长的方法，以及将组合物施用于其表面的医疗装置以及使用该组合物涂覆医疗装置的方法。

4. 发明申请

US20100285084A1 Antimicrobial coatings for medical devices and methods for making and using them 有权
标题翻译：医疗器械的抗微生物涂层及其制造和使用方法
公开(公告)号：US20100285084A1
公开(公告)日：2010-11-11
申请号：US11983930
申请日：2007-11-13
申请人： Zhongping Yang , Eunjoo Jin , Laura Christoferson , Rajiv Shah
发明人： Zhongping Yang , Eunjoo Jin , Laura Christoferson , Rajiv Shah
IPC分类号： A61F2/00 , B05D1/36 , A61K38/44 , A61P31/00 , A61N1/05
CPC分类号： A61L27/34 , A61L27/54 , A61L2300/11 , A61L2300/208
摘要： Embodiments of the invention provide methods for using compositions to inhibit microbial growth on a surface of a medical device having the composition applied thereto, to medical devices having the composition applied to a surface thereof and to methods for using the compositions to coat medical devices.
摘要翻译：本发明的实施方案提供使用组合物抑制其施用组合物的医疗装置的表面上的微生物生长的方法，以及将组合物施用于其表面的医疗装置以及使用该组合物涂覆医疗装置的方法。

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