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1. 发明申请

WO2013003815A3 NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS 审中-公开
标题翻译：近红外荧光染料具有较大的ST痕变化
公开(公告)号：WO2013003815A3
公开(公告)日：2013-04-25
申请号：PCT/US2012045116
申请日：2012-06-29
申请人： OREGON STATE , STRONGIN ROBERT MICHAEL , SIBRIAN-VAZQUEZ MARTHA , ESCOBEDO CORDOVA JORGE OMAR , LOWRY MARK ALLEN
发明人： STRONGIN ROBERT MICHAEL , SIBRIAN-VAZQUEZ MARTHA , ESCOBEDO CORDOVA JORGE OMAR , LOWRY MARK ALLEN
IPC分类号： C07D311/80 , C07D493/10 , G01N33/58 , G01N33/68
CPC分类号： G01N33/582 , C07D311/82 , C07D493/10 , C09B11/12 , C09B11/22 , C09B11/24 , C09B57/00 , G01N21/6486 , G01N33/49 , G01N33/493 , Y10T436/141111
摘要： Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure (I). At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together forms substituted or unsubstituted cycloalkyl or aryl.
摘要翻译：公开了近红外（NIR）染料的实施方案，以及用NIR染料检测分析物的方法和试剂盒。 NIR染料具有根据通用结构（I）的结构。 R1 / R2，R2 / R3，R3 / R4，R5 / R6，R6 / R7和/或R7 / R8中的至少一个一起形成取代或未取代的环烷基或芳基。

2. 发明申请

WO2013003812A2 ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES 审中-公开
标题翻译：使用近红外荧光素的分析物检测
公开(公告)号：WO2013003812A2
公开(公告)日：2013-01-03
申请号：PCT/US2012/045112
申请日：2012-06-29
申请人： THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY , STRONGIN, Robert Michael , SIBRIAN-VAZQUEZ, Martha , ESCOBEDO CORDOVA, Jorge Omar , LOWRY, Mark Allen
发明人： STRONGIN, Robert Michael , SIBRIAN-VAZQUEZ, Martha , ESCOBEDO CORDOVA, Jorge Omar , LOWRY, Mark Allen
CPC分类号： G01N33/582 , C07D405/14 , C09B11/24 , C09K9/02 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1088 , G01N33/52 , G01N33/6815 , G01N2800/28 , Y10T436/143333
摘要： Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R 1 /R 2 , R 2 /R 3 , R 3 /R 4 , R 5 /R 6 , R 6 /R 7 , and/or R 7 /R 8 together form a substituted or unsubstituted cycloalkyl or aryl.
摘要翻译：公开了用于选择性检测分析物的化合物的实施方案，以及用于用化合物检测分析物的方法和试剂盒。所述化合物是根据通用结构包括至少一个荧光团的桥联紫罗碱偶联物。R1，R2，R2，R3， R 3，R 3，R 4，R 5，R 6，R 5，R 5，R 5，R 6， R 6 / R 7和/或R 7 / R 8一起形成取代或未取代的环烷基或芳基

3. 发明申请

WO2002080428A2 OPEN RING ARCHITECTURES FOR OPTICAL WDM NETWORKS 审中-公开
标题翻译：光纤WDM网络的开环结构
公开(公告)号：WO2002080428A2
公开(公告)日：2002-10-10
申请号：PCT/US2002/009790
申请日：2002-03-29
申请人： ATOGA SYSTEMS, INC. , KILICCOTE, Han , OZVEREN, Cuneyt , LOWRY, Mark
发明人： KILICCOTE, Han , OZVEREN, Cuneyt , LOWRY, Mark
IPC分类号： H04J14/02
CPC分类号： H04J14/0291 , H04J14/0201 , H04J14/021 , H04J14/0213 , H04J14/0227 , H04J14/0241 , H04J14/0246 , H04J14/025 , H04J14/0283 , H04J14/0287
摘要： Methods and apparatuses of opening ring optical networks are disclosed, as optical nodes, for example open intercepts and closed intercepts, supporting open ring optical networks. Open ring optical networks can prevent optical wavelengths from traversing an optical node in an optically transparent network. Optical feedback can be prevented in open ring optical networks, for exymple optical networks containing optical amplifiers. Coherent crosstalk can be prevented in open ring optical networks. Some open ring networks further allow standard communication protection techniques that are typically associated with rings which are topologically closed. These network architectures can enable low cost-of-maintenace bandwidth upgrades to the entire network.
摘要翻译：公开了环形光网络的方法和装置，作为光节点，例如开放截距和闭路截距，支持开环光网络。开环光网络可以防止光波长穿过光学透明网络中的光节点。在光环路光网络中可以防止光反馈，包含光放大器的光纤网络。在开环光网络中可以防止相干串扰。一些开环网络还允许通常与拓扑关闭的环相关联的标准通信保护技术。这些网络架构可以实现对整个网络的低维护带宽升级。

4. 发明申请

WO2013003812A3 ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES 审中-公开
标题翻译：使用近红外荧光分析检测
公开(公告)号：WO2013003812A3
公开(公告)日：2013-04-11
申请号：PCT/US2012045112
申请日：2012-06-29
申请人： OREGON STATE , STRONGIN ROBERT MICHAEL , SIBRIAN-VAZQUEZ MARTHA , ESCOBEDO CORDOVA JORGE OMAR , LOWRY MARK ALLEN
发明人： STRONGIN ROBERT MICHAEL , SIBRIAN-VAZQUEZ MARTHA , ESCOBEDO CORDOVA JORGE OMAR , LOWRY MARK ALLEN
IPC分类号： C07D405/14 , C07D409/14 , G01N33/48 , G01N33/50
CPC分类号： G01N33/582 , C07D405/14 , C09B11/24 , C09K9/02 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1088 , G01N33/52 , G01N33/6815 , G01N2800/28 , Y10T436/143333
摘要： Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together form a substituted or unsubstituted cycloalkyl or aryl.
摘要翻译：公开了用于选择性检测分析物的化合物的实施方案，以及用于用化合物检测分析物的方法和试剂盒。所述化合物是根据通式结构包括至少一个荧光团的桥连紫罗兰缀合物。R1 / R2，R2 / R3，R3 / R4，R5 / R6，R6 / R7和/或R7 / R8中的至少一个一起形成取代基或未取代的环烷基或芳基。

5. 发明申请

WO2013003815A2 NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS 审中-公开
标题翻译：近红外荧光染料与大量的STOKES SHIFTS
公开(公告)号：WO2013003815A2
公开(公告)日：2013-01-03
申请号：PCT/US2012/045116
申请日：2012-06-29
申请人： THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY , STRONGIN, Robert, Michael , SIBRIAN-VAZQUEZ, Martha , ESCOBEDO CORDOVA, Jorge, Omar , LOWRY, Mark, Allen
发明人： STRONGIN, Robert, Michael , SIBRIAN-VAZQUEZ, Martha , ESCOBEDO CORDOVA, Jorge, Omar , LOWRY, Mark, Allen
CPC分类号： G01N33/582 , C07D311/82 , C07D493/10 , C09B11/12 , C09B11/22 , C09B11/24 , C09B57/00 , G01N21/6486 , G01N33/49 , G01N33/493 , Y10T436/141111
摘要： Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure (I). At least one of R 1 /R 2 , R 2 /R 3 , R 3 /R 4 , R 5 /R 6 , R 6 /R 7 , and/or R 7 /R 8 together forms substituted or unsubstituted cycloalkyl or aryl.
摘要翻译：公开了近红外（NIR）染料的实施方案以及用于用NIR染料检测分析物的方法和试剂盒。 NIR染料具有根据一般结构（I）的结构。 R 1 / R 2，R 2 / R 3，R 3 / R 4，R 5 / R 6，R 6 / R 7和/或R 7 / R 8中的至少一个一起形成取代或未取代的环烷基或芳基。

6. 发明申请

WO2009082618A2 FROZEN LONIC LIQUID MICROPARTICLES AND NANOPARTICLES, AND METHODS FOR THEIR SYNTHESIS AND USE 审中-公开
标题翻译：冷冻的离子液体微粒和纳米粒子及其合成和使用方法
公开(公告)号：WO2009082618A2
公开(公告)日：2009-07-02
申请号：PCT/US2008/086065
申请日：2008-12-09
申请人： BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE , THE UNITED STATES OF AMERICA AS REPRESENTED BY , BWAMBOK, David , WARNER, Isiah, M. , TESFAI, Aaron , EL-ZAHAB, Bilal, M. , BAKER, Gary, A. , FAKAYODE, Sayo, O. , LOWRY, Mark , TOLOCKA, Michael, P. , DE ROOY, Sergio
发明人： BWAMBOK, David , WARNER, Isiah, M. , TESFAI, Aaron , EL-ZAHAB, Bilal, M. , BAKER, Gary, A. , FAKAYODE, Sayo, O. , LOWRY, Mark , TOLOCKA, Michael, P. , DE ROOY, Sergio
IPC分类号： C09C3/00 , C09C1/00 , C09C1/48 , B82B3/00
CPC分类号： B82Y30/00 , D01D5/003 , Y10T428/2982 , Y10T428/2989
摘要： "Frozen ionic liquid" microparticles and nanoparticles are disclosed, as are alternative methods of making the particles. The particles may be monodisperse or polydisperse, with spherical or other shapes. The particles may be prepared without specialized equipment, and without harsh conditions. The microparticles and nanoparticles have uses in biomedical, materials, analytical, and other fields.
摘要翻译： “冷冻离子液体” 公开了微粒和纳米粒子，以及制备粒子的替代方法。颗粒可以是单分散的或多分散的，具有球形或其他形状。可以在没有专门设备的情况下制备颗粒，并且没有苛刻的条件。微粒和纳米粒子可用于生物医学，材料，分析和其他领域。

7. 发明申请

WO2008011508A1 FLUORESCENT XANTHENES AND WHITE LIGHT FLUOROPHORES 审中-公开
标题翻译：荧光XANTHENES和白光荧光
公开(公告)号：WO2008011508A1
公开(公告)日：2008-01-24
申请号：PCT/US2007/073864
申请日：2007-07-19
申请人： BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITYAND AGRICULTURAL AND MECHANICAL COLLEGE , STRONGIN, Robert, M. , WARNER, Isiah, M. , YANG, Youjun , LOWRY, Mark , FAKAYODE, Sayo, O. , ESCOBEDO CORDOVA, Jorge, O. , XU, Xiangyang
发明人： STRONGIN, Robert, M. , WARNER, Isiah, M. , YANG, Youjun , LOWRY, Mark , FAKAYODE, Sayo, O. , ESCOBEDO CORDOVA, Jorge, O. , XU, Xiangyang
IPC分类号： C07C245/00 , C07C37/00 , C09B11/00
CPC分类号： C07D311/78 , C09B11/06 , C09B11/22 , G01N1/30
摘要： Xanthene compounds are disclosed having fluorescence at multiple wavelengths. Also disclosed are methods for their synthesis and use. Some of the compounds fluoresce at three wavelengths, emitting white light. Uses include the imaging of biological tissues, illumination, and display technologies. Many of the compounds have large Stokes shifts, and are resistant to photobleaching. The fluorescence may be readily distinguished from that of endogenous fluorophores, and from that of most existing, commercially-available fluorescent probes. The compounds are well suited for use in "multiplexing" techniques. They exhibit clear isosbestic and isoemissive points, and have broad absorption and emission ranges.
摘要翻译：公开了在多个波长具有荧光的呫吨化合物。还公开了它们的合成和使用的方法。一些化合物在三个波长发出荧光，发出白光。用途包括生物组织成像，照明和显示技术。许多化合物具有大的斯托克斯位移，并且耐光漂白。荧光可以容易地与内源性荧光团的区别，以及大多数现有的市售荧光探针的荧光。该化合物非常适用于“复用”技术。它们表现出清晰的同位素和等位基因，具有广泛的吸收和发射范围。

8. 发明申请

WO2009082618A3 FROZEN LONIC LIQUID MICROPARTICLES AND NANOPARTICLES, AND METHODS FOR THEIR SYNTHESIS AND USE 审中-公开
标题翻译：冷冻液体微量元素和纳米颗粒及其合成和使用方法
公开(公告)号：WO2009082618A3
公开(公告)日：2009-10-08
申请号：PCT/US2008086065
申请日：2008-12-09
申请人： UNIV LOUISIANA STATE , US AGRICULTURE , WARNER ISIAH M , TESFAI AARON , EL-ZAHAB BILAL M , BWAMBOK DAVID , BAKER GARY A , FAKAYODE SAYO O , LOWRY MARK , TOLOCKA MICHAEL P , DE ROOY SERGIO
发明人： WARNER ISIAH M , TESFAI AARON , EL-ZAHAB BILAL M , BWAMBOK DAVID , BAKER GARY A , FAKAYODE SAYO O , LOWRY MARK , TOLOCKA MICHAEL P , DE ROOY SERGIO
IPC分类号： C09C3/00 , B82B3/00 , C09C1/00 , C09C1/48
CPC分类号： B82Y30/00 , D01D5/003 , Y10T428/2982 , Y10T428/2989
摘要： "Frozen ionic liquid" microparticles and nanoparticles are disclosed, as are alternative methods of making the particles. The particles may be monodisperse or polydisperse, with spherical or other shapes. The particles may be prepared without specialized equipment, and without harsh conditions. The microparticles and nanoparticles have uses in biomedical, materials, analytical, and other fields.
摘要翻译：公开了“冷冻离子液体”微粒和纳米颗粒，以及制备颗粒的替代方法。颗粒可以是单分散的或多分散的，具有球形或其它形状。颗粒可以在没有专门设备的情况下制备，并且在恶劣条件下。微粒和纳米颗粒在生物医学，材料，分析和其他领域都有应用。

9. 发明申请

WO02080453A3 METHODS AND APPARATUS FOR RECONFIGURABLE WDM LIGHTPATH RINGS 审中-公开
标题翻译：用于可重构波分复用光路环的方法和设备
公开(公告)号：WO02080453A3
公开(公告)日：2003-08-07
申请号：PCT/US0209672
申请日：2002-03-29
申请人： ATOGA SYSTEMS INC , OZVEREN CUNEYT M , SHAFFER STEPHEN , MENON PARAYATH GOPAL K , LOWRY MARK
发明人： OZVEREN CUNEYT M , SHAFFER STEPHEN , MENON PARAYATH GOPAL K , LOWRY MARK
IPC分类号： H04J14/02 , H04Q11/00
CPC分类号： H04J14/0291 , H04J14/0201 , H04J14/021 , H04J14/0213 , H04J14/0227 , H04J14/0241 , H04J14/0246 , H04J14/025 , H04J14/0283 , H04J14/0287
摘要： Methods and apparatus for dynamic bandwidth provisioning in wavelength division multiplexing (WDM) optical ring networks. A plurality of nodes within the network are configured to transmit optical signals at variable wavelengths and receive optical signals at a predetermined wavelengths. A network management system computer may be provided to communicate with the network nodes to direct the wavelengths at which each node transmits and receives. A series of one or more lightpath rings within the network are defined by selecting a first plurality of network nodes to provide a channel to support the optical transmission of a communication signal therebetween having a first bandwidth allocation. Each network node within the firt plurality of network nodes is instructed upon command by the network management system to transmit an optical signal at a predetermined wavelength that is to be received by only one other network node within the first plurality of network nodes to form a first series of optical links therebetween which in the aggregate form the lightpath ring. Each network node within the second plurality of network nodes is instructed upon command by the network management system to transmit an optical signal at a predetermined wavelength that is to be received by only one other network node within the second plurality of network nodes to form a second series of optical links therebetween which in the aggregate reforms the lightpath ring. Accordingly, the lightpath ring may be reformed upon command by the network management system by altering the number of network nodes within the first plurality of network nodes to define a second plurality of network nodes which dynamically provides the channel with a different bandwidth allocation.
摘要翻译：用于波分复用（WDM）光环网络中的动态带宽供应的方法和装置。网络内的多个节点被配置成以可变波长发送光信号并以预定波长接收光信号。可以提供网络管理系统计算机来与网络节点通信以指导每个节点发送和接收的波长。网络内的一系列一个或多个光路环通过选择第一多个网络节点来定义，以提供信道以支持其间具有第一带宽分配的通信信号的光学传输。根据网络管理系统的命令指示第一多个网络节点内的每个网络节点发送预定波长的光信号，该光信号将仅被第一多个网络节点内的一个其他网络节点接收以形成第一它们之间的一系列光学链路形成光路环。根据网络管理系统的命令指示第二多个网络节点内的每个网络节点发送预定波长的光信号，该光信号将仅由第二多个网络节点内的一个其他网络节点接收以形成第二它们之间的一系列光学链路在总体上重新形成了光路环。因此，可以根据网络管理系统的命令通过改变第一多个网络节点内的网络节点的数量来重新构造光路环，以定义动态地为该信道提供不同带宽分配的第二多个网络节点。

10. 发明申请

WO2002080453A2 METHODS AND APPARATUS FOR RECONFIGURABLE WDM LIGHTPATH RINGS 审中-公开
标题翻译：可重构WDM LIGHTPATH环的方法和装置
公开(公告)号：WO2002080453A2
公开(公告)日：2002-10-10
申请号：PCT/US2002/009672
申请日：2002-03-29
申请人： ATOGA SYSTEMS, INC. , OZVEREN, Cuneyt, M. , SHAFFER, Stephen , MENON, Parayath, Gopal, K. , LOWRY, Mark
发明人： OZVEREN, Cuneyt, M. , SHAFFER, Stephen , MENON, Parayath, Gopal, K. , LOWRY, Mark
IPC分类号： H04L12/00
CPC分类号： H04J14/0291 , H04J14/0201 , H04J14/021 , H04J14/0213 , H04J14/0227 , H04J14/0241 , H04J14/0246 , H04J14/025 , H04J14/0283 , H04J14/0287
摘要： Methods and apparatus for dynamic bandwidth provisioning in wavelength division multiplexing (WDM) optical ring networks. A plurality of nodes within the network are configured to transmit optical signals at variable wavelengths and receive optical signals at a predetermined wavelengths. A network management system computer may be provided to communicate with the network nodes to direct the wavelengths at which each node transmits and receives. A series of one or more lightpath rings within the network are defined by selecting a first plurality of network nodes to provide a channel to support the optical transmission of a communication signal therebetween having a first bandwidth allocation. Each network node within the firt plurality of network nodes is instructed upon command by the network management system to transmit an optical signal at a predetermined wavelength that is to be received by only one other network node within the first plurality of network nodes to form a first series of optical links therebetween which in the aggregate form the lightpath ring. Each network node within the second plurality of network nodes is instructed upon command by the network management system to transmit an optical signal at a predetermined wavelength that is to be received by only one other network node within the second plurality of network nodes to form a second series of optical links therebetween which in the aggregate reforms the lightpath ring. Accordingly, the lightpath ring may be reformed upon command by the network management system by altering the number of network nodes within the first plurality of network nodes to define a second plurality of network nodes which dynamically provides the channel with a different bandwidth allocation.
摘要翻译：用于波分复用（WDM）光环网络中动态带宽供应的方法和装置。网络内的多个节点被配置为以可变的波长传输光信号并接收预定波长的光信号。可以提供网络管理系统计算机以与网络节点进行通信，以指导每个节点发送和接收的波长。通过选择第一多个网络节点来提供网络中的一系列一个或多个光路环，以提供用于支持其间具有第一带宽分配的通信信号的光传输的信道。在网络管理系统的指令下指示多个网络节点内的每个网络节点以预定波长发送光信号，该预定波长将仅由第一多个网络节点内的另一个网络节点接收，以形成第一它们之间的一系列光学链路聚集形成光路环。第二多个网络节点内的每个网络节点由网络管理系统命令指示，以在仅由第二多个网络节点内的另一个网络节点接收的预定波长上发送光信号，以形成第二个在它们之间的一系列光学链路在总体上改变光路环。因此，可以通过网络管理系统的命令来改变光路环，通过改变第一多个网络节点内的网络节点的数量来定义第二个多个网络节点，该第二多个网络节点动态地向频道提供不同的带宽分配。

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