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1. 发明申请

WO2011008948A1 TYMPANIC MEMBRANE PRESSURE EQUALIZATION TUBE DELIVERY SYSTEM 审中-公开
标题翻译：典型膜压平衡管传送系统
公开(公告)号：WO2011008948A1
公开(公告)日：2011-01-20
申请号：PCT/US2010/042128
申请日：2010-07-15
申请人： ACCLARENT, INC. , LIU, Greg , GIROTRA, Rohit , MORRISS, John, H. , VRANY, Julie, D. , HA, Hung, V. , KNODEL, Bryon , WALKER, Jeffrey, A. , GROSS, Thomas, Daniel , CLOPP, Mathew, D. , ANDREAS, Bernard, H.
发明人： LIU, Greg , GIROTRA, Rohit , MORRISS, John, H. , VRANY, Julie, D. , HA, Hung, V. , KNODEL, Bryon , WALKER, Jeffrey, A. , GROSS, Thomas, Daniel , CLOPP, Mathew, D. , ANDREAS, Bernard, H.
IPC分类号： A61F11/00 , A61B17/34
CPC分类号： A61F11/002 , A61B17/3468
摘要： Systems and methods are provided for automatically forming an incision in a tympanic membrane of an ear and placing a tympanic membrane pressure equalization tube into the incision. The systems include a housing with a shaft extending therefrom. A mechanism is disposed within the housing. A distal end of the shaft is placed against a tympanic membrane, and the mechanism is triggered to causes the tympanic membrane to be automatically incised and dilated and a tympanic membrane pressure equalization tube to be placed in the dilated incision.
摘要翻译：提供了系统和方法，用于在耳朵的鼓膜中自动形成切口并将鼓膜压力平衡管放置在切口中。这些系统包括具有从其延伸的轴的壳体。机构设置在壳体内。将轴的远端放置在鼓膜上，并且触发该机构以使鼓膜自动切开和扩张，并将鼓膜压力平衡管放置在扩张切口中。

2. 发明申请

WO2019148048A1 SELF-ADJUSTING DEVICE 审中-公开
公开(公告)号：WO2019148048A1
公开(公告)日：2019-08-01
申请号：PCT/US2019/015302
申请日：2019-01-25
申请人： CHINE, LLC , MACMAHON, John , ANDERSON, Evan , LIU, Greg C.
发明人： MACMAHON, John , ANDERSON, Evan , LIU, Greg C.
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2481 , A61B17/064 , A61B17/068 , A61B17/10 , A61B17/2812 , A61B90/06 , A61B2017/00243 , A61B2017/00398 , A61B2017/00407 , A61B2017/00473 , A61B2017/00738 , A61B2017/00858 , A61B2017/0649 , A61B2090/061 , A61B2090/0801 , A61F2/2442 , A61F2/2451 , A61F2/246 , A61F2/2478 , A61F2002/2484 , A61F2210/0033 , A61F2210/0076 , A61F2220/0016 , A61F2220/0025 , A61F2220/0033 , A61F2230/0013 , A61F2230/0023 , A61F2250/0002 , A61F2250/0003 , A61F2250/0004 , A61F2250/001 , A61F2250/0029 , A61F2250/0036 , A61F2250/006 , A61F2250/0064
摘要： A self-adjusting device configured to be placed in contact with tissue/organ and apply mechanical force to the tissue/organ to achieve an improvement of functioning of the tissue/organ The self-adjusting capabilities can be carried out by three functional subsystems that can be packaged either in a single, integrated system or in separate modules. A sensing subsystem senses the tissue/organ and sends at least one type of sensing signal characteristic of functioning of the tissue/organ to a controlling subsystem The controlling subsystem processes the signal with an algorithm to determine if a configuration of the device needs to be changed or a force applied to the tissue/organ needs to be changed. An actuating subsystem can be controlled by the controlling subsystem to affect the configuration/force change when needed. A feedback loop is provided to keep the controlling subsystem up to date as to the state of the actuating subsystem.

3. 发明申请

WO2008131195A2 SYSTEM AND METHOD FOR THE SIMULTANEOUS BILATERAL TREATMENT OF TARGET TISSUES WITHIN THE EARS 审中-公开
标题翻译：耳蜗内靶向组织同时双重治疗的系统与方法
公开(公告)号：WO2008131195A2
公开(公告)日：2008-10-30
申请号：PCT/US2008060779
申请日：2008-04-18
申请人： ACCLARENT INC , CLIFFORD ANTON , LIU GREG , MORRISS JOHN , MAKOWER JOSHUA , FACTEAU WILLIAM , GOLDFARB ERIC , CHANG JOHN Y , SHAHOIAN ERIK JAMES
发明人： CLIFFORD ANTON , LIU GREG , MORRISS JOHN , MAKOWER JOSHUA , FACTEAU WILLIAM , GOLDFARB ERIC , CHANG JOHN Y , SHAHOIAN ERIK JAMES
IPC分类号： A61F11/00
CPC分类号： A61M31/00 , A61B5/0077 , A61B2017/00787 , A61F11/002 , A61M2210/0662 , A61N1/30 , A61N1/306
摘要： A) Systems and methods for bilateral treatment of a patient having a head with a first ear and a second ear function by aligning a first device with a target tissue of the first ear; aligning a second device with a target tissue of the second ear; and therapeutically remodeling, with synchronization, the target tissues of the first and second ear with the first and second aligned devices, respectively. B) Systems and methods for treating a patient having a head with a first ear and a second ear function by mounting a support system to the head of the patient so that the support system is aligned with a target tissue of the first ear; applying a therapeutic agent to the first ear by energizing an iontophoresis electrode supported by the support system; and actuating a device while the device is supported by the support system so that the device therapeutically remodels the target tissue of the first ear. C) Systems and methods for treating a patient having an ear canal and a target tissue function by positioning a fluid or gel in the ear canal, the fluid or gel comprising a therapeutic agent; retaining the fluid or gel with a support structure, the support structure supporting an electrode and a battery; and applying the agent from the fluid or gel to the target tissue by energizing the electrode with an iontophoresis potential from the battery. D) Systems and methods for treating a patient having a head with a first ear and a second ear, function by mounting a support structure to the head of the patient; aligning the support structure with a target tissue in an ear canal of the first ear; stabilizing the support structure relative to the target tissue by injecting a material into the canal and hardening the material; and actuating a device while the device is supported by the support system so that the device therapeutically remodels the target tissue of the first ear. E) Systems and methods for treating a patient having a head with a first ear and a second ear, function by aligning a first device with a tympanic membrane of the first ear; inputting a command to an input device operatively coupled to the first device to generate a signal; and actuating the first device in response to the signal so as to drive a penetrator of the device through the tympanic membrane.
摘要翻译： A）通过将第一装置与第一耳朵的目标组织对准来双侧治疗具有第一耳朵和第二耳朵功能的患者的系统和方法; 将第二装置与第二耳朵的目标组织对准; 以及分别与第一和第二对准的装置分别对第一和第二耳朵的目标组织进行同步化的治疗重塑。 B）通过将支撑系统安装到患者的头部来治疗具有第一耳朵和第二耳朵功能的头部的患者的系统和方法，使得支撑系统与第一耳朵的目标组织对准; 通过对由所述支撑系统支撑的离子电渗电极通电来将治疗剂施加到所述第一耳朵; 以及当所述装置由所述支撑系统支撑时启动装置，使得所述装置治疗性地改造所述第一耳朵的目标组织。 C）通过将流体或凝胶定位在耳道中来治疗患有耳道和靶组织功能的患者的系统和方法，所述流体或凝胶包含治疗剂; 用支撑结构保持流体或凝胶，支撑结构支撑电极和电池; 以及通过从所述电池离子电渗电位激发所述电极，将所述药剂从所述流体或凝胶施加到所述靶组织。 D）用于治疗患有具有第一耳朵和第二耳朵的头部的患者的系统和方法通过将支撑结构安装到患者的头部而起作用; 将支撑结构与第一耳的耳道中的目标组织对准; 通过将材料注入到管道中并使材料硬化来相对于目标组织稳定支撑结构; 以及当所述装置由所述支撑系统支撑时启动装置，使得所述装置治疗性地改造所述第一耳朵的目标组织。 E）用于治疗患有具有第一耳朵和第二耳朵的头部的患者的系统和方法，其功能是使第一装置与第一耳朵的鼓膜对准; 向可操作地耦合到所述第一设备的输入设备输入命令以产生信号; 以及响应于所述信号致动所述第一装置，以便通过所述鼓膜驱动所述装置的穿透器。

4. 发明申请

WO2010075502A3 SILENT EFFUSION REMOVAL 审中-公开
标题翻译：静电消除
公开(公告)号：WO2010075502A3
公开(公告)日：2010-08-05
申请号：PCT/US2009069388
申请日：2009-12-23
申请人： ACCLARENT INC , MORRISS JOHN H , LIU GREG , GIROTRA ROHIT , VO TOM THANH , NEWHAUSER RICHARD ROY , JENKINS THOMAS , MAKOWER JOSHUA
发明人： MORRISS JOHN H , LIU GREG , GIROTRA ROHIT , VO TOM THANH , NEWHAUSER RICHARD ROY , JENKINS THOMAS , MAKOWER JOSHUA
IPC分类号： A61F11/00 , A61M3/02 , A61M11/00
CPC分类号： A61F11/002 , A61F11/006 , A61M1/0031 , A61M1/008 , A61M3/0262 , A61M3/0279 , A61M2210/0675
摘要： A method is disclosed for clearing effusion from an ear. The method may include applying liquid to an ear canal, which is proximal to a perforated tympanic membrane, which is proximal to a middle ear containing effusion, applying an ear device to seal and pressurize the liquid inside the ear canal, the ear device regulating the amount of pressure inside the ear canal, and inducing a Eustachian tube, which is distal to the middle ear, to open, which causes the fluid to displace the effusion into the Eustachian tube.
摘要翻译：公开了一种从耳朵清除渗出物的方法。该方法可以包括将液体施加到耳道，所述耳道接近穿孔鼓膜，所述鼓膜接近含有渗出液的中耳，施加耳朵装置以密封和加压耳道内的液体，耳朵装置调节耳道内的压力量，以及诱导位于中耳远端的咽鼓管打开，导致流体将渗出液置于咽鼓管内。

5. 发明申请

WO2010075502A9 SILENT EFFUSION REMOVAL 审中-公开
公开(公告)号：WO2010075502A9
公开(公告)日：2010-07-01
申请号：PCT/US2009/069388
申请日：2009-12-23
申请人： ACCLARENT, INC. , MORRISS, John, H. , LIU, Greg , GIROTRA, Rohit , VO, Tom, Thanh , NEWHAUSER, Richard, Roy , JENKINS, Thomas , MAKOWER, Joshua
发明人： MORRISS, John, H. , LIU, Greg , GIROTRA, Rohit , VO, Tom, Thanh , NEWHAUSER, Richard, Roy , JENKINS, Thomas , MAKOWER, Joshua
IPC分类号： A61F11/00 , A61M11/00 , A61M3/02
摘要： A method is disclosed for clearing effusion from an ear. The method may include applying liquid to an ear canal, which is proximal to a perforated tympanic membrane, which is proximal to a middle ear containing effusion, applying an ear device to seal and pressurize the liquid inside the ear canal, the ear device regulating the amount of pressure inside the ear canal, and inducing a Eustachian tube, which is distal to the middle ear, to open, which causes the fluid to displace the effusion into the Eustachian tube.

6. 发明申请

WO2010075502A2 SILENT EFFUSION REMOVAL 审中-公开
标题翻译：静音排出
公开(公告)号：WO2010075502A2
公开(公告)日：2010-07-01
申请号：PCT/US2009069388
申请日：2009-12-23
申请人： ACCLARENT INC , MORRISS JOHN H , LIU GREG , GIROTRA ROHIT , VO TOM THANH , NEWHAUSER RICHARD ROY , JENKINS THOMAS , MAKOWER JOSHUA
发明人： MORRISS JOHN H , LIU GREG , GIROTRA ROHIT , VO TOM THANH , NEWHAUSER RICHARD ROY , JENKINS THOMAS , MAKOWER JOSHUA
IPC分类号： A61F11/00 , A61M3/02 , A61M11/00
CPC分类号： A61F11/002 , A61F11/006 , A61M1/0031 , A61M1/008 , A61M3/0262 , A61M3/0279 , A61M2210/0675
摘要： A method is disclosed for clearing effusion from an ear. The method may include applying liquid to an ear canal, which is proximal to a perforated tympanic membrane, which is proximal to a middle ear containing effusion, applying an ear device to seal and pressurize the liquid inside the ear canal, the ear device regulating the amount of pressure inside the ear canal, and inducing a Eustachian tube, which is distal to the middle ear, to open, which causes the fluid to displace the effusion into the Eustachian tube.
摘要翻译：公开了一种用于清除耳朵积液的方法。该方法可以包括将液体施加到邻近穿孔鼓膜的耳道，该耳道在含有渗液的中耳的近侧，应用耳朵装置以密封和加压耳道内的液体，耳朵装置调节耳道内的压力量以及诱导中耳远端的咽鼓管打开，这导致流体将渗出物排出到咽鼓管中。

7. 发明申请

WO2010014894A1 SYSTEMS AND METHODS FOR ANESTHETIZING EAR TISSUE 审中-公开
标题翻译：用于麻醉组织的系统和方法
公开(公告)号：WO2010014894A1
公开(公告)日：2010-02-04
申请号：PCT/US2009/052395
申请日：2009-07-31
申请人： ACCLARENT, INC. , MORRISS, John, H. , LIU, Greg , GIROTRA, Rohit , ANDREAS, Bernard, H. , BARON, Scott, J. , HAYTER, Paul, G. , JENKINS, Thomas , NEWHAUSER, Richard, R. , WALKER, Jeffrey, A.
发明人： MORRISS, John, H. , LIU, Greg , GIROTRA, Rohit , ANDREAS, Bernard, H. , BARON, Scott, J. , HAYTER, Paul, G. , JENKINS, Thomas , NEWHAUSER, Richard, R. , WALKER, Jeffrey, A.
IPC分类号： A61N1/30 , A61F11/08 , A61M1/00
CPC分类号： A61N1/306 , A61F11/00 , A61M1/0088 , A61M19/00 , A61M2205/3341 , A61M2210/0662 , A61N1/044 , A61N1/303 , A61N1/36021
摘要： A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The method involves using the system on a human or animal subject.
摘要翻译：公开了一种用于鼓膜离子电渗麻醉的系统和方法。该系统通常包括耳塞和电极装置。耳塞包括用于将耳塞密封在耳道中的至少一个密封构件。该方法涉及将该系统用于人或动物受试者。

8. 发明申请

WO2008131195A3 SYSTEM AND METHOD FOR THE SIMULTANEOUS BILATERAL TREATMENT OF TARGET TISSUES WITHIN THE EARS 审中-公开
公开(公告)号：WO2008131195A3
公开(公告)日：2008-10-30
申请号：PCT/US2008/060779
申请日：2008-04-18
申请人： ACCLARENT, INC. , CLIFFORD, Anton , LIU, Greg , MORRISS, John , MAKOWER, Joshua , FACTEAU, William , GOLDFARB, Eric , CHANG, John Y. , SHAHOIAN, Erik James
发明人： CLIFFORD, Anton , LIU, Greg , MORRISS, John , MAKOWER, Joshua , FACTEAU, William , GOLDFARB, Eric , CHANG, John Y. , SHAHOIAN, Erik James
IPC分类号： A61F11/00
摘要： Systems and methods for bilateral treatment of a patient having a head with a first ear and a second ear function by aligning a first device with a target tissue of the first ear, aligning a second device with a target tissue of the second ear, and therapeutically remodeling, with synchronization, the target tissues of the first and second ear with the first and second aligned devices, respectively Systems and methods for treating a patient having a head with a first ear and a second ear function by mounting a support system to the head of the patient so that the support system is aligned with a target tissue of the first ear, applying a therapeutic agent to the first ear by energizing an iontophoresis electrode supported by the support system, and actuating a device while the device is supported by the support system.

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