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1. 发明申请

WO2012149003A3 APPARATUS AND METHOD FOR ESTIMATING FORMATION LITHOLOGY USING X-RAY FLOURESCENCE 审中-公开
标题翻译：使用X射线衍射估算地层岩石的装置和方法
公开(公告)号：WO2012149003A3
公开(公告)日：2013-03-14
申请号：PCT/US2012034969
申请日：2012-04-25
申请人： BAKER HUGHES INC , LI FUSHENG
发明人： LI FUSHENG
IPC分类号： G01V5/12 , E21B49/00 , G01N23/223
CPC分类号： E21B49/06 , E21B49/10 , G01N23/223 , G01N33/241 , G01N2223/076
摘要： An apparatus for estimating properties of an earth formation includes a carrier configured to be disposed in a borehole in the earth formation, and a sample retriever configured to remove a sample of the earth formation, the sample including solid components of the earth formation. The apparatus also includes an analysis assembly including a chamber disposed with the carrier and configured to hold the sample, an X-ray source configured to irradiate the sample with X-ray radiation while the sample is disposed in the chamber, and one or more X-ray detectors configured to detect radiation emitted from the sample in response to irradiation from the X-ray source.
摘要翻译：用于估计地层性质的装置包括构造成设置在地层中的钻孔中的载体和被构造成移除地层的样品的样品回收器，样品包括地层的固体组分。该装置还包括分析组件，其包括设置有载体并被配置为保持样品的腔室，X射线源被配置为在样品设置在腔室中时用X射线辐射照射样品，以及一个或多个X 射线检测器被配置为响应于来自X射线源的照射来检测从样品发射的辐射。

2. 发明申请

WO2006038908A2 ANCESTRAL AND COT VIRAL SEQUENCES, PROTEINS AND IMMUNOGENIC COMPOSITIONS 审中-公开
标题翻译：肠癌和COT病毒序列，蛋白质和免疫组化
公开(公告)号：WO2006038908A2
公开(公告)日：2006-04-13
申请号：PCT/US2005/005311
申请日：2005-02-17
申请人： UNIVERSITY OF WASHINGTON , MULLINS, James, I. , RODRIGO, Allen, G. , LEARN, Gerald, H. , LI, Fusheng , NICKLE, David, C. , JENSEN, Mark, A.
发明人： MULLINS, James, I. , RODRIGO, Allen, G. , LEARN, Gerald, H. , LI, Fusheng , NICKLE, David, C. , JENSEN, Mark, A.
IPC分类号： C12Q1/70 , C07H21/04 , C07K14/16 , C12N15/867 , C07K14/02
CPC分类号： C07K14/005 , C07H21/04 , C12N7/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , C12N2770/24222 , C12Q1/703
摘要： The present invention is directed to ancestral and COT nucleic acid and amino acid sequences, methods for producing such sequences and uses thereof, including prophylactic and diagnostic uses.
摘要翻译：本发明涉及祖代和COT核酸和氨基酸序列，用于产生此类序列及其用途的方法，包括预防和诊断用途。

3. 发明申请

WO2006038908A3 ANCESTRAL AND COT VIRAL SEQUENCES, PROTEINS AND IMMUNOGENIC COMPOSITIONS 审中-公开
标题翻译：肠癌和COT病毒序列，蛋白质和免疫组化
公开(公告)号：WO2006038908A3
公开(公告)日：2008-09-12
申请号：PCT/US2005005311
申请日：2005-02-17
申请人： UNIV WASHINGTON , MULLINS JAMES I , RODRIGO ALLEN G , LEARN GERALD H , LI FUSHENG , NICKLE DAVID C , JENSEN MARK A
发明人： MULLINS JAMES I , RODRIGO ALLEN G , LEARN GERALD H , LI FUSHENG , NICKLE DAVID C , JENSEN MARK A
IPC分类号： C07H21/02 , C07K14/16 , C07K14/18 , C12N5/00
CPC分类号： C07K14/005 , C07H21/04 , C12N7/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , C12N2770/24222 , C12Q1/703
摘要： The present invention is directed to ancestral and COT nucleic acid and amino acid sequences, methods for producing such sequences and uses thereof, including prophylactic and diagnostic uses.
摘要翻译：本发明涉及祖代和COT核酸和氨基酸序列，用于产生此类序列及其用途的方法，包括预防和诊断用途。

4. 发明申请

WO2004045369A3 NUCLEAR RECEPTOR-BASED DIAGNOSTIC, THERAPEUTIC, AND SCREENING METHODS 审中-公开
标题翻译：基于核受体的诊断，治疗和筛选方法
公开(公告)号：WO2004045369A3
公开(公告)日：2007-03-01
申请号：PCT/US0336229
申请日：2003-11-12
申请人： NURA INC , GAITANARIS GEORGE A , BERGMANN JOHN E , GRACEROV ALEXANDER , HOHMANN JOHN , LI FUSHENG , MADISEN LINDA , MCILWAIN KELLIE L , PAVLOVA MARIA N , VASSILATIS DEMETRI , ZENG HONGKUI
发明人： GAITANARIS GEORGE A , BERGMANN JOHN E , GRACEROV ALEXANDER , HOHMANN JOHN , LI FUSHENG , MADISEN LINDA , MCILWAIN KELLIE L , PAVLOVA MARIA N , VASSILATIS DEMETRI , ZENG HONGKUI
IPC分类号： C12Q1/68 , A61B20060101 , C07K14/72 , C12P19/34 , G01N33/68
CPC分类号： G01N33/6875 , C07K14/723 , G01N2500/04 , G01N2500/10 , G01N2800/00
摘要： The present invention features nuclear receptor polypeptides, polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the nuclear receptor polypeptides and polynucleotides of the invention, and for treating conditions associated with nuclear receptor dysfunction with the nuclear receptor polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate nuclear receptor activity or levels.
摘要翻译：本发明的特征在于核受体多肽，多核苷酸，重组材料和转基因小鼠，以及它们的生产方法。多肽和多核苷酸可用于例如诊断和治疗疾病和病症的方法。本发明还提供了使用本发明的核受体多肽和多核苷酸鉴定化合物（例如激动剂或拮抗剂）以及用核受体多肽，多核苷酸或鉴定的化合物治疗与核受体功能障碍相关的病症的方法。本发明还提供用于检测与不适当核受体活性或水平相关的疾病或病症的诊断测定。

5. 发明申请

WO2004045369A2 NUCLEAR RECEPTOR-BASED DIAGNOSTIC, THERAPEUTIC, AND SCREENING METHODS 审中-公开
标题翻译：基于核受体的诊断，治疗和筛选方法
公开(公告)号：WO2004045369A2
公开(公告)日：2004-06-03
申请号：PCT/US2003/036229
申请日：2003-11-12
申请人： NURA, INC. , GAITANARIS, George, A. , BERGMANN, John, E. , GRACEROV, Alexander , HOHMANN, John , LI, Fusheng , MADISEN, Linda , MCILWAIN, Kellie, L. , PAVLOVA, Maria, N. , VASSILATIS, Demetri , ZENG, Hongkui
发明人： GAITANARIS, George, A. , BERGMANN, John, E. , GRACEROV, Alexander , HOHMANN, John , LI, Fusheng , MADISEN, Linda , MCILWAIN, Kellie, L. , PAVLOVA, Maria, N. , VASSILATIS, Demetri , ZENG, Hongkui
IPC分类号： A61B
CPC分类号： G01N33/6875 , C07K14/723 , G01N2500/04 , G01N2500/10 , G01N2800/00 , Y02A50/52
摘要： The present invention features nuclear receptor polypeptides, polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the nuclear receptor polypeptides and polynucleotides of the invention, and for treating conditions associated with nuclear receptor dysfunction with the nuclear receptor polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate nuclear receptor activity or levels.
摘要翻译：本发明的特征在于核受体多肽，多核苷酸，重组材料和转基因小鼠，以及其生产方法。多肽和多核苷酸可用于例如诊断和治疗疾病和病症的方法。本发明还提供了使用本发明的核受体多肽和多核苷酸鉴定化合物（例如激动剂或拮抗剂）以及用核受体多肽，多核苷酸或鉴定的化合物治疗与核受体功能障碍相关的病症的方法。本发明还提供用于检测与不适当核受体活性或水平相关的疾病或病症的诊断测定。

6. 发明申请

WO0160838A3 AIDS ANCESTRAL VIRUSES AND VACCINES 审中-公开
标题翻译：艾滋病毒病毒和疫苗
公开(公告)号：WO0160838A3
公开(公告)日：2002-01-24
申请号：PCT/US0105288
申请日：2001-02-16
申请人： UNIV WASHINGTON , MULLINS JAMES I , RODRIGO ALLEN G , LEARN GERALD H , LI FUSHENG
发明人： MULLINS JAMES I , RODRIGO ALLEN G , LEARN GERALD H , LI FUSHENG
IPC分类号： C12N15/09 , A61K39/00 , A61K39/21 , A61P31/14 , A61P31/18 , C07K14/155 , C07K14/16 , C07K14/18 , C07K16/08 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/85 , C12P21/08 , A01N37/18 , A61K38/00 , A61K39/38 , A61K39/42 , C07H21/02 , C07H21/04 , C07K14/00 , C07K16/00 , C12N5/00 , C12N5/02 , C12N5/06 , C12N5/16 , C12N15/63 , C12P21/06 , C12Q1/70 , G01N33/53
CPC分类号： C07K14/005 , A61K39/00 , C12N15/85 , C12N2740/15022 , C12N2740/16122 , C12N2770/24222 , C12Q1/703
摘要： The present invention is directed to ancestral HIV nucleic acid and amino acid sequences, methods for producing such sequences and uses thereof, including prophylactic and diagnostic uses.
摘要翻译：本发明涉及祖代HIV核酸和氨基酸序列，用于产生此类序列的方法及其用途，包括预防和诊断用途。

7. 发明申请

WO2013032606A1 METHODS FOR SOURCELESS DENSITY DOWNHOLE MEASUREMENT USING PULSED NEUTRON GENERATOR 审中-公开
标题翻译：使用脉冲中子发生器进行无源密度测井的方法
公开(公告)号：WO2013032606A1
公开(公告)日：2013-03-07
申请号：PCT/US2012/048242
申请日：2012-07-26
申请人： BAKER HUGHES INCORPORATED , LI, Fusheng , HAN, Xiaogang
发明人： LI, Fusheng , HAN, Xiaogang
IPC分类号： G01V5/14 , G21G4/02 , G01T3/00
CPC分类号： G01V5/101
摘要： Disclosed is a method for estimating a density of an earth formation penetrated by a borehole. The method includes: emitting a pulse of fast neutrons into the formation during a neutron-pulse time interval; detecting gamma-rays due to inelastic scattering and thermal capture of the emitted neutrons in the formation to provide a gamma-ray energy spectrum due to the inelastic scattering and the thermal capture during a first time interval within the neutron-pulse time interval and to provide a time spectrum of counts or count rates due to thermal capture during a second time interval occurring after the neutron-pulse time interval; determining a macroscopic capture cross section of the formation from a decay in the time spectrum of counts or count rates; determining an elemental weight fraction from the gammaray energy spectrum; and estimating the density of the formation using the macroscopic capture cross section and the elemental weight fraction.
摘要翻译：公开了一种用于估计钻孔渗透的地层的密度的方法。该方法包括：在中子脉冲时间间隔内将快中子脉冲发射到地层中; 由于在中子脉冲时间间隔期间的第一时间间隔期间由于非弹性散射和热捕获而在地层中发射的中子的非弹性散射和热捕获来检测γ射线以提供伽马射线能谱，并提供在中子脉冲时间间隔后发生的第二时间间隔期间由于热捕获引起的计数或计数率的时间谱; 从计数或计数率的时间谱中的衰减确定地层的宏观捕获截面; 从伽马能谱中确定元素重量分数; 并使用宏观捕获截面和元素重量分数来估计地层的密度。

8. 发明申请

WO2012149003A2 APPARATUS AND METHOD FOR ESTIMATING FORMATION LITHOLOGY USING X-RAY FLOURESCENCE 审中-公开
标题翻译：使用X射线衍射估算地层岩石的装置和方法
公开(公告)号：WO2012149003A2
公开(公告)日：2012-11-01
申请号：PCT/US2012/034969
申请日：2012-04-25
申请人： BAKER HUGHES INCORPORATED , LI, Fusheng
发明人： LI, Fusheng
IPC分类号： G01V5/12 , E21B49/00 , G01N23/223
CPC分类号： E21B49/06 , E21B49/10 , G01N23/223 , G01N33/241 , G01N2223/076
摘要： An apparatus for estimating properties of an earth formation includes a carrier configured to be disposed in a borehole in the earth formation, and a sample retriever configured to remove a sample of the earth formation, the sample including solid components of the earth formation. The apparatus also includes an analysis assembly including a chamber disposed with the carrier and configured to hold the sample, an X-ray source configured to irradiate the sample with X-ray radiation while the sample is disposed in the chamber, and one or more X-ray detectors configured to detect radiation emitted from the sample in response to irradiation from the X-ray source.
摘要翻译：用于估计地层的性质的装置包括构造成设置在地层中的钻孔中的载体和被构造成移除地层的样品的样本捕获器，样品包括地层的固体组分。该装置还包括分析组件，其包括设置有载体并被配置为保持样品的腔室; X射线源，被配置为在样品设置在腔室中时用X射线辐射照射样品，以及一个或多个X 射线检测器被配置为响应于来自X射线源的照射来检测从样品发射的辐射。

9. 发明申请

WO2004040000A9 G PROTEIN COUPLED RECEPTORS AND USES THEREOF 审中-公开
标题翻译： G蛋白偶联受体及其用途
公开(公告)号：WO2004040000A9
公开(公告)日：2009-08-27
申请号：PCT/US0328226
申请日：2003-09-09
申请人： NURA INC , GAITANARIS GEORGE A , BERGMANN JOHN E , GRAGEROV ALEXANDER , HOHMANN JOHN , LI FUSHENG , MADISEN LINDA , MCILWAIN KELLIE L , PAVLOVA MARIA N , VASSILATIS DEMETRI , ZENG HONGKUI
发明人： GAITANARIS GEORGE A , BERGMANN JOHN E , GRAGEROV ALEXANDER , HOHMANN JOHN , LI FUSHENG , MADISEN LINDA , MCILWAIN KELLIE L , PAVLOVA MARIA N , VASSILATIS DEMETRI , ZENG HONGKUI
IPC分类号： C07K14/705 , A61K38/00 , C07K14/72 , C12N15/12 , C12Q1/68
CPC分类号： G01N33/74 , A61K38/00 , C07K14/705 , C07K14/723 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N2333/726 , G01N2500/04 , G01N2500/10
摘要： The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.

10. 发明申请

WO2004040000A2 G PROTEIN COUPLED RECEPTORS AND USES THEREOF 审中-公开
标题翻译： G蛋白偶联受体及其用途
公开(公告)号：WO2004040000A2
公开(公告)日：2004-05-13
申请号：PCT/US2003/028226
申请日：2003-09-09
申请人： PRIMAL, INC. , GAITANARIS, George, A. , BERGMANN, John, E. , GRAGEROV, Alexander , HOHMANN, John , LI, Fusheng , MADISEN, Linda , MCILWAIN, Kellie, L. , PAVLOVA, Maria, N. , VASSILATIS, Demetri , ZENG, Hongkui
发明人： GAITANARIS, George, A. , BERGMANN, John, E. , GRAGEROV, Alexander , HOHMANN, John , LI, Fusheng , MADISEN, Linda , MCILWAIN, Kellie, L. , PAVLOVA, Maria, N. , VASSILATIS, Demetri , ZENG, Hongkui
IPC分类号： C12Q
CPC分类号： G01N33/74 , A61K38/00 , C07K14/705 , C07K14/723 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N2333/726 , G01N2500/04 , G01N2500/10 , Y02A50/463 , Y02A50/469 , Y02A50/475 , Y02A50/48 , Y02A50/491 , Y02A50/492
摘要： The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要翻译：本发明提供GPCR多肽和多核苷酸，重组材料和转基因小鼠，以及其生产方法。多肽和多核苷酸可用于例如诊断和治疗疾病和病症的方法。本发明还提供了使用本发明的GPCR多肽和多核苷酸鉴定化合物（例如激动剂或拮抗剂）以及用GPCR多肽，多核苷酸或鉴定的化合物治疗与GPCR功能障碍相关的病症的方法。本发明还提供用于检测与不适当GPCR活性或水平相关的疾病或病症的诊断测定。

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