专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2003042724A1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES 审中-公开
标题翻译：用于修饰生物医学文章表面的方法
公开(公告)号：WO2003042724A1
公开(公告)日：2003-05-22
申请号：PCT/EP2002/012658
申请日：2002-11-12
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , CHABRECEK, Peter , LEUKEL, Jörg , BIEDERMANN, Hynek , LOHMANN, Dieter
发明人： CHABRECEK, Peter , LEUKEL, Jörg , BIEDERMANN, Hynek , LOHMANN, Dieter
IPC分类号： G02B1/04
CPC分类号： A61L27/50 , A61L27/34 , A61L2400/18 , G02B1/043
摘要： The invention relates to a process for coating a material surface, comrising the steps of: a) providing an inorganic or organic bulk material; b) providing one or more polyionic materials at least one of them comprising covalently bound initiator moieties for radical polymerization; c) applying the polyionic material of step (b) to the bulk material of step (a), thereby forming a hydrophilic layer on the bulk material surface; and d) graft polymerizing a hydrophilic monomer or macromonomer onto said polyionic material. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译：本发明涉及一种用于涂覆材料表面的方法，其包括以下步骤：a）提供无机或有机散装材料; b）提供一种或多种聚离子材料，其中至少一种包括共价键合的引发剂部分用于自由基聚合; c）将步骤（b）的聚离子材料施加到步骤（a）的本体材料中，从而在散装材料表面上形成亲水层; 和d）将亲水单体或大分子单体接枝聚合到所述聚离子材料上。通过本发明的方法可获得的涂覆制品具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的所需特性，因此可用于制造生物医学制品如眼科装置。

2. 发明申请

WO2002094331A1 BOTTLE-BRUSH TYPE COATINGS WITH ENTANGLED HYDROPHILIC POLYMER 审中-公开
标题翻译：瓶盖类型涂料，带有环氧聚合物
公开(公告)号：WO2002094331A1
公开(公告)日：2002-11-28
申请号：PCT/EP2002/005495
申请日：2002-05-17
申请人： NOVARTIS AG , NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H. , CHABRECEK, Peter , LEUKEL, Jörg , LOHMANN, Dieter
发明人： CHABRECEK, Peter , LEUKEL, Jörg , LOHMANN, Dieter
IPC分类号： A61L27/34
CPC分类号： A61L27/34
摘要： The invention relates to a process for coating a material surface comprising the steps of: (a) providing an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; (b) graft polymerizing a hydrophilic ethylenically unsaturated macromonomer from the bulk material surface in the presence of a biocompatible hydrophilic polymer being devoid of polymerizable ethylenically unsaturated groups and thereby entrapping said hydrophilic polymer within the polymer matrix formed by the polymerization of the macromonomer. Composite materials obtainable according to the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译：本发明涉及一种用于涂覆材料表面的方法，包括以下步骤：（a）提供与其表面引发剂部分共价结合的无机或有机本体材料用于自由基聚合; （b）在生物相容性亲水性聚合物存在下，在不存在可聚合的烯属不饱和基团的情况下，从本体材料表面接枝聚合亲水性烯属不饱和大单体，从而将所述亲水性聚合物截留在通过大分子单体聚合形成的聚合物基质中。根据本发明的方法可获得的复合材料具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的期望特性，因此可用于制造生物医学制品如眼科装置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式