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1. 发明公开

EP2906143A4 CARDIAC TREATMENT SYSTEM AND METHOD 无效
标题翻译： HERZBEHANDLUNGSSYSTEM UNDERVERHREN
公开(公告)号：EP2906143A4
公开(公告)日：2016-07-13
申请号：EP13844676
申请日：2013-10-14
申请人： MARDIL INC , HJELLE AARON , COHN WILLIAM E , SCHROEDER RICHARD F , BUCK JAMES F , LEINSING KARL R
发明人： HJELLE AARON , COHN WILLIAM E , SCHROEDER RICHARD F , BUCK JAMES F , LEINSING KARL R
IPC分类号： A61F2/24 , A61F2/02 , A61M39/22
CPC分类号： A61F2/2481 , A61B2090/3966 , A61F2002/2484 , A61F2002/9517 , A61F2250/0003 , A61F2250/0098 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/12 , A61M1/122 , A61M2205/32 , D04B21/12 , D10B2509/08

2. 发明申请

WO2014059433A3 CARDIAC TREATMENT SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2014059433A3
公开(公告)日：2014-04-17
申请号：PCT/US2013/064895
申请日：2013-10-14
申请人： MARDIL, INC. , HJELLE, Aaron , COHN, William, E. , SCHROEDER, Richard, F. , BUCK, James, F. , LEINSING, Karl, R.
发明人： HJELLE, Aaron , COHN, William, E. , SCHROEDER, Richard, F. , BUCK, James, F. , LEINSING, Karl, R.
IPC分类号： A61F2/02 , A61F2/00
摘要： Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

3. 发明申请

WO2012031135A1 MINIMALLY INVASIVE SURGICAL INSTRUMENT FOR DELIVERY OF CARDIAC DEVICES 审中-公开
标题翻译：用于输送心脏装置的微型外科手术仪器
公开(公告)号：WO2012031135A1
公开(公告)日：2012-03-08
申请号：PCT/US2011/050225
申请日：2011-09-01
申请人： MARDIL, INC. , LEINSING, Karl,R. , RAMAN, JaiShankar
发明人： LEINSING, Karl,R. , RAMAN, JaiShankar
IPC分类号： A61F2/00
CPC分类号： A61F2/2466 , A61F2/2481 , A61F2250/0003
摘要： A minimally invasive surgical instrument for delivering an external basal annuloplasty device to a heart includes a hollow shaft with a telescopically center tube extending from an end of the hollow shaft. The center tube includes a heart gripping member. A plurality of delivery prongs are slidably coupled to the hollow shaft, each having a distal portion with an expandable wire member for holding the external basal annuloplasty device. A sleeve is telescopically coupled to the expandable wire member. A wire slide is coupled to a proximal portion of the expandable wire member and a sleeve slide is coupled to a proximal portion of the sleeve. The external basal annuloplasty device is mountable on the plurality of delivery prongs by inserting each expandable wire member into a respective pocket on the external basal annuloplasty device.
摘要翻译：用于将外部基底瓣膜成形术装置递送到心脏的微创手术器械包括具有从中空轴的端部延伸的可伸缩中心管的空心轴。中心管包括心脏夹持构件。多个输送叉可滑动地联接到中空轴，每个具有远端部分，该远端部分具有用于保持外部基瓣瓣成形术装置的可扩张线构件。套筒可伸缩地联接到可膨胀线材上。电线滑块联接到可扩展电线构件的近端部分，并且套筒滑动件联接到套筒的近侧部分。通过将每个可膨胀线构件插入到外部基准瓣环成形术装置上的相应口袋中，外部基瓣瓣成形术装置可安装在多个输送叉上。

4. 发明申请

WO2014145812A1 PORTABLE POSITIVE AIRWAY PRESSURE APPARATUS AND METHOD FOR ATTENUATING THE NOISE EMITTED THEREFROM 审中-公开
标题翻译：便携式气动压力装置及其发射噪声的方法
公开(公告)号：WO2014145812A1
公开(公告)日：2014-09-18
申请号：PCT/US2014030640
申请日：2014-03-17
申请人： HUMAN DESIGN MEDICAL LLC , LIBRETT KEVIN SCOTT , LEINSING KARL R
发明人： LIBRETT KEVIN SCOTT , LEINSING KARL R
IPC分类号： A61M16/00 , A61M16/06 , A61M16/08 , G10K11/04 , G10K11/16
CPC分类号： A61M16/0066 , A61M16/0051 , A61M16/0063 , A61M16/0069 , A61M16/022 , A61M16/06 , A61M16/0816 , A61M16/0858 , A61M16/0875 , A61M16/107 , A61M2016/0027 , A61M2205/3355 , A61M2205/42 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/75 , A61M2205/8206 , A61M2207/00 , F04D29/4213 , F04D29/4226 , F04D29/663 , F04D29/664 , F04D29/665 , F05D2250/51 , F05D2260/96 , G10K11/04 , G10K11/161 , Y10T29/49826
摘要： The systems, apparatus and methods described herein provide a quiet, light-weight, and portable system and apparatus for providing positive air pressure to a patient. The application discloses a CPAP apparatus (100, 300, 400, 500, 600, 700, 900) comprising: a housing (180, 380, 381, 780, 784, 980) defining a first acoustic chamber (402, 502, 602, 930) with a first inlet port (412, 512, 612, 613, 910), and a second acoustic chamber (414, 514, 614, 934) with a blower unit (140, 416, 516, 616, 740, 940) and a second inlet port (422, 507, 622, 917) extending from the first to the second chamber. The CPAP apparatus can be portable. A system can comprise the apparatus comprising an adapter (160, 360, 760, 960) in communication with the blower unit and extending outward from the apparatus, and a detachable patient interface system (165, 365, 965). The apparatus can include alternatively a single acoustic chamber (130, 230, 730) with an inlet port (110, 710) most of whose length is within the acoustic chamber, and an outlet port (139, 739). The blower unit can be vibrationally isolated. The dimensions of inlet ports and acoustic chambers may be proportionally related, in particular defining an acoustic low-pass filter. The application discloses a method for reducing noise in a portable CPAP device with first and second acoustic chambers, including routing the flow of air through the device, wherein the first inlet is sealed from and passes through the second chamber into the first acoustic chamber, and the flow of air is routed through an outlet port sealed from and passing through the first chamber.
摘要翻译：本文所述的系统，装置和方法提供了一种安静，轻便和便携的系统和装置，用于向患者提供正气压。该应用公开了一种CPAP设备（100,300,400,500,600,700,900），包括：壳体（180,380,381,780,784,980），其限定第一声学室（402,502,602，具有第一入口端口（412,512,612,613,910）和具有鼓风机单元（140,416,516,616,740,940）的第二声室（414,514,614,934）以及从第一室延伸到第二室的第二入口端口（422,507,622,917）。 CPAP装置可以是便携式的。系统可以包括与鼓风机单元连通并从设备向外延伸的适配器（160,360,760,960）以及可拆卸的患者接口系统（165,365,965）的设备。该装置可以包括具有其大部分长度在声室内的入口端口（110,710）的单个声学室（130,230,730）和出口（139,739）。鼓风机单元可以振动隔离。入口端口和声学室的尺寸可以成比例地相关，特别是限定声学低通滤波器。本申请公开了一种用于降低具有第一和第二声室的便携式CPAP装置中的噪声的方法，包括使空气流穿过装置，其中第一入口被密封并穿过第二室进入第一声室，以及空气流通过密封并通过第一室的出口。

5. 发明申请

WO2014059433A2 CARDIAC TREATMENT SYSTEM AND METHOD 审中-公开
标题翻译： CARDIAC治疗系统和方法
公开(公告)号：WO2014059433A2
公开(公告)日：2014-04-17
申请号：PCT/US2013064895
申请日：2013-10-14
申请人： MARDIL INC , HJELLE AARON , COHN WILLIAM E , SCHROEDER RICHARD F , BUCK JAMES F , LEINSING KARL R
发明人： HJELLE AARON , COHN WILLIAM E , SCHROEDER RICHARD F , BUCK JAMES F , LEINSING KARL R
IPC分类号： A61F2/02 , A61F2/00
CPC分类号： A61F2/2481 , A61B2090/3966 , A61F2002/2484 , A61F2002/9517 , A61F2250/0003 , A61F2250/0098 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/12 , A61M1/122 , A61M2205/32 , D04B21/12 , D10B2509/08
摘要： Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.
摘要翻译：用于向患者心脏的区域提供局部压力以改善心脏功能的装置和方法，包括：（a）由柔性生物相容性材料制成的护套，所述护套具有容纳在心脏周围的敞开的顶端和底部这是收到心脏的顶端周围; （b）至少一个设置在护套内表面上的可充气囊状物，可膨胀囊状物具有邻近护套定位的非弹性外表面和弹性内表面，使得囊状物的膨胀使得囊状物基本上向内变形成对心脏区域施加局部压力。

6. 发明申请

WO2007005394A1 TISSUE ANCHOR AND METHODS OF USING THE SAME 审中-公开
标题翻译：组织锚固器及其使用方法
公开(公告)号：WO2007005394A1
公开(公告)日：2007-01-11
申请号：PCT/US2006/024897
申请日：2006-06-27
申请人： MITRALIGN, INC. , SUGIMOTO, Hiroatsu , CALL, Aaron, M. , LEINSING, Karl, R.
发明人： SUGIMOTO, Hiroatsu , CALL, Aaron, M. , LEINSING, Karl, R.
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0469 , A61B17/0487 , A61B2017/00243 , A61B2017/00783 , A61B2017/0406 , A61B2017/0417 , A61B2017/0419 , A61B2017/0458 , A61B2017/0464 , A61B2017/048 , A61B2017/0496
摘要： A tissue anchor (10) includes an anchor member (14) formed from a generally flexible material. An activation member, which may be a tensioning member (12), causes proximal and distal end portions (14a, 14b) of the anchor member (14) to move toward each other into a shortened configuration suitable for anchoring against the tissue (20). The tissue anchor (10) can optionally be deployed and activated using a catheter device (50).
摘要翻译：组织锚固件（10）包括由大体柔性材料形成的锚定构件（14）。可以是张紧构件（12）的致动构件使得锚固构件（14）的近端部分（14a，14b）朝向彼此移动成适于锚定在组织（20）上的缩短构型，。可以使用导管装置（50）任选地展开和激活组织锚（10）。

7. 发明申请

WO2014145812A9 PORTABLE POSITIVE AIRWAY PRESSURE APPARATUS AND METHOD FOR ATTENUATING THE NOISE EMITTED THEREFROM 审中-公开
公开(公告)号：WO2014145812A9
公开(公告)日：2014-09-18
申请号：PCT/US2014/030640
申请日：2014-03-17
申请人： HUMAN DESIGN MEDICAL, LLC , LIBRETT, Kevin, Scott , LEINSING, Karl, R.
发明人： LIBRETT, Kevin, Scott , LEINSING, Karl, R.
IPC分类号： A61M16/00 , A61M16/08 , A61M16/06 , G10K11/04 , G10K11/16
摘要： The systems, apparatus and methods described herein provide a quiet, light-weight, and portable system and apparatus for providing positive air pressure to a patient. The application discloses a CPAP apparatus (100, 300, 400, 500, 600, 700, 900) comprising: a housing (180, 380, 381, 780, 784, 980) defining a first acoustic chamber (402, 502, 602, 930) with a first inlet port (412, 512, 612, 613, 910), and a second acoustic chamber (414, 514, 614, 934) with a blower unit (140, 416, 516, 616, 740, 940) and a second inlet port (422, 507, 622, 917) extending from the first to the second chamber. The CPAP apparatus can be portable. A system can comprise the apparatus comprising an adapter (160, 360, 760, 960) in communication with the blower unit and extending outward from the apparatus, and a detachable patient interface system (165, 365, 965). The apparatus can include alternatively a single acoustic chamber (130, 230, 730) with an inlet port (110, 710) most of whose length is within the acoustic chamber, and an outlet port (139, 739). The blower unit can be vibrationally isolated. The dimensions of inlet ports and acoustic chambers may be proportionally related, in particular defining an acoustic low-pass filter. The application discloses a method for reducing noise in a portable CPAP device with first and second acoustic chambers, including routing the flow of air through the device, wherein the first inlet is sealed from and passes through the second chamber into the first acoustic chamber, and the flow of air is routed through an outlet port sealed from and passing through the first chamber.

8. 发明申请

WO2009032307A1 HEART BAND WITH FILLABLE CHAMBERS TO MODIFY HEART VALVE FUNCTION 审中-公开
标题翻译：心脏带带有可更换的阀门来修改心脏瓣膜功能
公开(公告)号：WO2009032307A1
公开(公告)日：2009-03-12
申请号：PCT/US2008/010421
申请日：2008-09-04
申请人： MARDIL, INC. , LEINSING, Karl R. , RAMAN, Jaishankar
发明人： LEINSING, Karl R. , RAMAN, Jaishankar
IPC分类号： A61M1/10
CPC分类号： A61F2/2481
摘要： The present invention relates to an external heart device, having a layered band dimensioned to be received around a patient's heart, which also includes at least one fillable chamber between the layers in the band that functions to apply localized pressure to the outside of the heart when filled. More particularly, the fillable chambers are positioned such that they exert an inward radial force on a heart valve. Areas between the fillable chambers may also be sized and positioned to form a bridge of little to no pressure over the vascular structures of the heart.
摘要翻译：本发明涉及一种外部心脏装置，其具有尺寸适于围绕患者心脏接收的分层带，其还包括在带中的层之间的至少一个可填充室，其用于将局部压力施加到心脏的外部，填充。更具体地，可填充室被定位成使得它们在心脏瓣膜上施加向内的径向力。可填充腔室之间的区域也可以被定尺寸和定位成在心脏血管结构上形成几乎没有压力的桥梁。

9. 发明申请

WO2007140309A2 LOCKERS FOR SURGICAL TENSIONING MEMBERS AND METHODS OF USING THE SAME TO SECURE SURGICAL TENSIONING MEMBERS 审中-公开
标题翻译：外科紧张会员的使用者及其使用方法安全手术张力会员
公开(公告)号：WO2007140309A2
公开(公告)日：2007-12-06
申请号：PCT/US2007/069761
申请日：2007-05-25
申请人： MITRALIGN, INC. , CALL, Aaron, M. , LEINSING, Karl, R. , MODOONO, Paul, T. , SUGIMOTO, Hiroatsu , MCNAMARA, Edward, I. , LANE, Joseph, P. , MURPHY, Matthew, J. , SANSOUCY, Michael, R. , CAHALANE, Steven, D. , LEE, Christopher, C. , ROBINSON, Jason, H.
发明人： CALL, Aaron, M. , LEINSING, Karl, R. , MODOONO, Paul, T. , SUGIMOTO, Hiroatsu , MCNAMARA, Edward, I. , LANE, Joseph, P. , MURPHY, Matthew, J. , SANSOUCY, Michael, R. , CAHALANE, Steven, D. , LEE, Christopher, C. , ROBINSON, Jason, H.
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0456 , A61B2017/0458 , A61B2017/0488
摘要： A locker {100) for securing one or more tensioning members (12) includes a locker body (102) having a first aperture (112), a second aperture (114), and a passageway (110) extending therebetween. A pin (106) is coupled to the locker body (102) so as to traverse the passageway (110) and is movable between a latent condition wherein the tensioning members (12) are movable with respect to the locker body (102), and an activated condition wherein the tensioning members (12) are prevented from moving relative to the locker body (102). A method of using a suture locker (100) includes delivering the suture locker (100) to a surgical site via a catheter assembly (159) and actuating the pin (106) so as to move the locker (100) from the latent condition to the activated condition.
摘要翻译：用于固定一个或多个张紧构件（12）的储物柜（100）包括具有第一孔（112），第二孔（114）和在其间延伸的通道（110）的储物柜本体（102）。销（106）联接到储物柜主体（102），以便穿过通道（110）并且可以在张紧构件（12）相对于储物柜主体（102）可移动的潜在状态之间移动;以及激活状态，其中防止张紧构件（12）相对于储物柜主体（102）移动。使用缝合线器（100）的方法包括经由导管组件（159）将缝合线锁（100）输送到外科手术部位并且致动销（106），以将储物柜（100）从潜伏状态移动到激活状态。

10. 发明公开

EP2906151A4 CARDIAC TREATMENT SYSTEM AND METHOD 有权转让
标题翻译：心脏治疗系统和方法
公开(公告)号：EP2906151A4
公开(公告)日：2016-07-13
申请号：EP13845313
申请日：2013-10-14
申请人： MARDIL INC , HJELLE AARON , COHN WILLIAM E , SCHROEDER RICHARD F , BUCK JAMES F , LEINSING KARL R
发明人： HJELLE AARON , COHN WILLIAM E , SCHROEDER RICHARD F , BUCK JAMES F , LEINSING KARL R
IPC分类号： A61F2/24 , A61F2/02 , A61M39/22
CPC分类号： A61F2/2481 , A61B2090/3966 , A61F2002/2484 , A61F2002/9517 , A61F2250/0003 , A61F2250/0098 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/12 , A61M1/122 , A61M2205/32 , D04B21/12 , D10B2509/08

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