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1. 发明授权

EP3192391B1 MASCARA FOR EYELASH MAKEUP 有权
公开(公告)号：EP3192391B1
公开(公告)日：2019-12-11
申请号：EP14901747.7
申请日：2014-10-14
申请人： Lee, Hye Won , Lee, Sang Dea
发明人： LEE, Hye Won
IPC分类号： A46B9/02 , A46D1/04

2. 发明公开

EP3192391A4 MASCARA FOR EYELASH MAKEUP 有权
公开(公告)号：EP3192391A4
公开(公告)日：2018-05-23
申请号：EP14901747
申请日：2014-10-14
申请人： LEE HYE WON , LEE SANG DEA
发明人： LEE HYE WON
IPC分类号： A45D34/04 , A46B13/00
CPC分类号： A46B3/00 , A45D34/04 , A45D40/262 , A46B9/021 , A46B9/026 , A46B13/006 , A46B2200/1053 , A46D1/04
摘要： The present invention relates to mascara for eyelash makeup and, more specifically, to mascara for eyelash makeup, which is produced by winding a brush band around a brush shaft in a spiral form and then coupling the brush band to the brush shaft.

3. 发明公开

EP3192391A1 MASCARA FOR EYELASH MAKEUP 有权
标题翻译： MASCARA为眼睫毛妆
公开(公告)号：EP3192391A1
公开(公告)日：2017-07-19
申请号：EP14901747.7
申请日：2014-10-14
申请人： Lee, Hye Won
发明人： Lee, Hye Won
IPC分类号： A45D34/04
摘要： The present invention relates to mascara for eyelash makeup and, more specifically, to mascara for eyelash makeup, which is produced by winding a brush band around a brush shaft in a spiral form and then coupling the brush band to the brush shaft.
摘要翻译：本发明涉及用于睫毛化妆的睫毛膏，并且更具体地涉及通过将刷带以螺旋形式缠绕在刷轴周围并且然后将刷带结合到刷轴上而制成的用于睫毛化妆的睫毛膏。

4. 发明申请

WO2012169745A2 METHOD AND DEVICE FOR CHANNEL MEASUREMENT IN A WIRELESS LAN SYSTEM 审中-公开
标题翻译：无线LAN系统中信道测量的方法和装置
公开(公告)号：WO2012169745A2
公开(公告)日：2012-12-13
申请号：PCT/KR2012004335
申请日：2012-06-01
申请人： LG ELECTRONICS INC , SNU R&DB FOUNDATION , SOHN ILL SOO , CHOI SUNG HYUN , YOO SEUNG MIN , LEE HYE WON , CHOI MUN HWAN , SEOK YONG HO , LEE OK HWAN
发明人： SOHN ILL SOO , CHOI SUNG HYUN , YOO SEUNG MIN , LEE HYE WON , CHOI MUN HWAN , SEOK YONG HO , LEE OK HWAN
IPC分类号： H04B7/26 , H04B7/02 , H04W84/12
CPC分类号： H04W24/08 , H04B7/0452 , H04B7/0617 , H04B7/0634 , H04B7/065
摘要： The present invention relates to a method and device for channel measurement in a wireless LAN system. A station (STA) receives a plurality of sounding frames from an access point (AP), estimates the plurality of sounding frames in order to generate long-term channel state information (LCSI), provides the generated LCSI to the AP as feedback, and receives from the AP a group identifier (ID) management frame comprising information on a group ID determined on the basis of the LCSI.
摘要翻译：本发明涉及无线LAN系统中的信道测量方法和装置。站点（STA）从接入点（AP）接收多个探测帧，估计多个探测帧以产生长期信道状态信息（LCSI），将生成的LCSI作为反馈提供给AP，以及从AP接收包括基于LCSI确定的组ID的信息的组标识符（ID）管理帧。

5. 发明申请

WO2012148046A1 ANTICANCER AND CANCER-SENSITIZING COMPOSITION COMPRISING RRP12 INHIBITOR 审中-公开
标题翻译：包含RRP12抑制剂的抗感染药和敏感剂组合物
公开(公告)号：WO2012148046A1
公开(公告)日：2012-11-01
申请号：PCT/KR2011/006715
申请日：2011-09-09
申请人： SAMSUNG LIFE PUBLIC WELFARE FOUNDATION , SEO, Sung Wook , LEE, Hye Won
发明人： SEO, Sung Wook , LEE, Hye Won
IPC分类号： A61K39/395 , A61K38/17 , A61K48/00 , A61P35/00
CPC分类号： C07K16/18 , A61K31/704 , A61K31/7088 , A61K31/713 , C12N15/113 , C12N2310/14 , G01N33/5023 , G01N2333/4703 , A61K2300/00
摘要： Disclosed are an anticancer and cancer-sensitizing composition, comprising as an active ingredient an inhibitor against the expression of an RRP12 (ribosomal RNA processing 12 homolog) gene or an inhibitor against the activity of RRP12, a method for screening an anticancer agent or a cancer sensitizer, and a method for treating cancer and inhibiting anticancer drug resistance, comprising administering the inhibitor to a subject. Showing anticancer and cancer sensitization effects, the composition can be used to treat RRP12-mediated cancer. In addition, the composition inhibits the chemoresistance of cancerous cells to enhance the activity of anticancer agents. Thus, the composition may be applied to the development of effective anticancer agents and anticancer drug aids.
摘要翻译：公开了抗癌和致敏组合物，其包含作为活性成分的抗RRP12（核糖体RNA加工12同系物）基因的表达抑制剂或抗RRP12的活性的抑制剂，抗癌剂或癌症的筛选方法敏化剂，以及治疗癌症和抑制抗癌药物耐药性的方法，包括对受试者施用抑制剂。显示抗癌和致敏作用，该组合物可用于治疗RRP12介导的癌症。此外，该组合物抑制癌细胞的化学抗性以增强抗癌剂的活性。因此，该组合物可以用于开发有效的抗癌剂和抗癌药物辅助剂。

6. 发明申请

WO2010079919A3 METHOD FOR SCREENING MATRIX METALLOPROTEINASE 审中-公开
标题翻译：筛选基质金属蛋白酶的方法
公开(公告)号：WO2010079919A3
公开(公告)日：2010-10-21
申请号：PCT/KR2009007913
申请日：2009-12-29
申请人： KOREA RES INST OF BIOSCIENCE , SONG JAE JUN , CHOI JONG HYUN , KIM BO HYE , CHOI NACK SHICK , HAN YUN JON , LEE HYE WON , LEE SEUNG GOO , KIM JOONG SU
发明人： SONG JAE JUN , CHOI JONG HYUN , KIM BO HYE , CHOI NACK SHICK , HAN YUN JON , LEE HYE WON , LEE SEUNG GOO , KIM JOONG SU
IPC分类号： C12Q1/34 , G01N33/561
CPC分类号： C12Q1/34 , G01N33/561
摘要： The present invention relates to a method of screening and activity detection for at least two different matrix metalloproteinases and more specifically to a method wherein a sample containing enzymes is subjected to gel electrophoresis, and then the sample is subjected to electrical migration in a multi-layered substrate gel having different substrates to analyze the multi-layered substrate gel, so that at least two substrate breakdown enzymes may be simultaneously screened and their activities detected. The method for screening and enzyme activity detection of matrix metalloproteinases according to the invention has the advantage that a sample is loaded on one gel, unlike the existing method, so that at least two matrix metalloproteinases can be screened. In addition, it is also useful as it has the advantage that direct screening of an unknown enzyme from a microorganism or an environmental source is accelerated.
摘要翻译：本发明涉及对至少两种不同的基质金属蛋白酶进行筛选和活性检测的方法，更具体地涉及一种方法，其中将含有酶的样品进行凝胶电泳，然后将样品进行多层电迁移底物凝胶具有不同的底物以分析多层底物凝胶，从而可以同时筛选至少两种底物分解酶并检测它们的活性。根据本发明的用于基质金属蛋白酶筛选和酶活性检测的方法具有以下优点：与现有方法不同，将样品加载在一个凝胶上，从而可以筛选至少两种基质金属蛋白酶。此外，它也有用，因为它具有加速从微生物或环境来源直接筛选未知酶的优点。

7. 发明申请

WO2005019162A1 HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF 审中-公开
标题翻译：羟基酸衍生物及其制备方法
公开(公告)号：WO2005019162A1
公开(公告)日：2005-03-03
申请号：PCT/KR2004/002143
申请日：2004-08-26
申请人： AMOREPACIFIC CORPORATION , RHO, Ho, Sik , BAEK, Heung, Soo , KIM, Su, Jong , KIM, Su, Nam , CHAE, Byung, Geun , LEE, Byoung, Seok , KIM, Bae, Hwan , CHOI, Gyu, Ho , SON, Eui, Dong , LEE, Hae, Kwang , LEE, Hye, Won , CHO, Jun-Cheol , KIM, Duck, Hee , CHANG, Ih, Seop , LEE, Ok, Sub
发明人： RHO, Ho, Sik , BAEK, Heung, Soo , KIM, Su, Jong , KIM, Su, Nam , CHAE, Byung, Geun , LEE, Byoung, Seok , KIM, Bae, Hwan , CHOI, Gyu, Ho , SON, Eui, Dong , LEE, Hae, Kwang , LEE, Hye, Won , CHO, Jun-Cheol , KIM, Duck, Hee , CHANG, Ih, Seop , LEE, Ok, Sub
IPC分类号： C07C259/06
CPC分类号： A61K8/40 , A61Q19/08 , C07C259/06 , C07C259/10 , C07C2603/74
摘要： The present invention provides hydroxamic acid derivatives represented by the following formula (I), having anti-aging efficacy and a method for preparation thereof: wherein, R 1 is or, herein, R 5 and R 6 each independently represents a hydrogen atom, a C 1 -C 10 alkyl group or a C 3 -C 6 cyclic alkyl group; R 2 is CONH, NHCO, CONR 7 or NR 7 CO, herein, R 7 represents a C 1 -C 10 alkyl group; R 3 is (CH) n -, herein, n=0 or 1; and R 4 is a hydrogen atom or a C 1 -C 10 alkyl group. Further, the present invention provides skin-care external compositions for preventing skin aging, containing said hydroxamic acid derivatives represented by the formula (I) as an active ingredient.
摘要翻译：本发明提供具有抗衰老功效的下式（I）表示的异羟肟酸衍生物及其制备方法：其中，R 1为或（R 5和R 6）各自独立地表示氢原子，C 1 -C 10 烷基或C 3 -C 6环烷基; R2是CONH，NHCO，CONR7或NR7CO，这里，R7代表C1-C10烷基; R3是（CH）n-，这里n = 0或1; 且R 4为氢原子或C 1 -C 10烷基。此外，本发明提供了含有式（I）所示的异羟肟酸衍生物作为有效成分的防止皮肤老化的护肤外用组合物。

8. 发明申请

WO2012111939A2 METHOD OF COMMUNICATION BASED ON CONTROLLING RECEIVE CHAIN IN WIRELESS LOCAL AREA NETWORK AND APPARATUS FOR THE SAME 审中-公开
标题翻译：基于无线局域网中控制接收链的通信方法及其装置
公开(公告)号：WO2012111939A2
公开(公告)日：2012-08-23
申请号：PCT/KR2012000949
申请日：2012-02-09
申请人： LG ELECTRONICS INC , SNU R&DB FOUNDATION , SOHN ILL SOO , CHOI SUNG HYUN , YOO SEUNG MIN , LEE HYE WON , CHOI MUN HWAN , SEOK YONG HO , LEE OK HWAN
发明人： SOHN ILL SOO , CHOI SUNG HYUN , YOO SEUNG MIN , LEE HYE WON , CHOI MUN HWAN , SEOK YONG HO , LEE OK HWAN
IPC分类号： H04B7/04 , H04W52/02 , H04W84/12
CPC分类号： H04W72/1263 , H04B7/0452 , H04B7/0877 , H04L1/06 , H04W84/12
摘要： A method of communication based on a receive chain control, performed by a receiver, in a wireless local area network is provided. The method includes: receiving a frame from a transmitter, the frame indicating a multi receive chain operation, activating at least one receive chain, each receive chain processing a received signal transmitted through each spatial stream, and receiving at least one data field from the transmitter through the at least one activated receive chain.
摘要翻译：提供了一种在无线局域网中基于由接收机执行的接收链控制的通信方法。该方法包括：从发射机接收帧，该帧指示多接收链操作;激活至少一个接收链;每个接收链处理通过每个空间流发送的接收信号;以及从发射机接收至少一个数据字段通过至少一个激活的接收链。

9. 发明申请

WO2006075808A1 PHARMACEUTICAL COMPOSITION COMPRISING A P25/CDK5 INHIBITOR FOR PREVENTING OR TREATING A NEURODEGENERATIVE DISEASE 审中-公开
标题翻译：包含P25 / CDK5抑制剂的药物组合物，用于预防或治疗神经病变疾病
公开(公告)号：WO2006075808A1
公开(公告)日：2006-07-20
申请号：PCT/KR2005/000098
申请日：2005-01-12
申请人： INJE UNIVERSITY , CHUNG, Sul-Hee , HA, Ilho , SON, Mi-Young , LEE, Hye-Won
发明人： CHUNG, Sul-Hee , HA, Ilho , SON, Mi-Young , LEE, Hye-Won
IPC分类号： A61K31/381 , A61P25/28
CPC分类号： A61K31/381
摘要： A pharmaceutical composition for preventing or treating a neurodegenerative disease comprises a compound inhibiting a P25/CDK (cycline-dependent kinase 5) complex as an active ingredient. Also disclosed is a method for screening a compound capable of preventing or treating a neurodegenerative disease, which comprises the steps of a) reacting a candidate compound with a P25/CDK5 complex and beta-site APP (amyloid precursor protein)-cleaving enzyme 1 (BACEl) or treating a mammalian cell expressing P25 with the candidate compound, and measuring BACE l phosphorylation; and b) comparing the measured BACEl phosphorylation with that of a control group employing no candidate compound, and identifying a compound reducing BACEl phosphorylation compared to the control group. The compound inhibiting the P25/CDK5 complex may be useful for preventing or treating a neurodegenerative disease including Alzheimer's disease because it inhibits BACEl phosphorylation and reduces the secretion of β-amyloid and the hyperphosphorylation of Tau.
摘要翻译：用于预防或治疗神经变性疾病的药物组合物包括抑制P25 / CDK（cycline-dependent kinase 5）复合物作为活性成分的化合物。还公开了一种筛选能够预防或治疗神经变性疾病的化合物的方法，其包括以下步骤：a）使候选化合物与P25 / CDK5复合体和β-位点APP（淀粉样蛋白前体蛋白）切割酶1（ BACE1）或用候选化合物处理表达P25的哺乳动物细胞，并测量BACE1磷酸化; 和b）比较测定的BACE1磷酸化与不使用候选化合物的对照组的BACE1磷酸化，并且与对照组相比，鉴定减少BACE1磷酸化的化合物。抑制P25 / CDK5复合物的化合物可用于预防或治疗包括阿尔茨海默病在内的神经变性疾病，因为它抑制BACE1磷酸化并降低β-淀粉样蛋白的分泌和Tau的过度磷酸化。

10. 发明申请

WO2004078954A1 BIODEGRADABLE DUAL POROUS SCAFFOLD WRAPPED WITH SEMI-PERMEABLE MEMBRANE AND TISSUE CELL CULTURE USING THEREOF 审中-公开
标题翻译：使用其可渗透的双重多孔膜和可渗透的膜和组织细胞培养物
公开(公告)号：WO2004078954A1
公开(公告)日：2004-09-16
申请号：PCT/KR2004/000054
申请日：2004-01-14
申请人： YONSEI UNIVERSITY , KIM, Jung-Hyun , LEE, Hye-Won , CHOI, Sung-Wook
发明人： KIM, Jung-Hyun , LEE, Hye-Won , CHOI, Sung-Wook
IPC分类号： C12N5/00
CPC分类号： A61L27/56 , A61F2002/30762 , A61F2002/30766 , A61L27/20 , C12N5/0068 , C12N2533/40 , C12N2533/74 , C08L5/04
摘要： Disclosed is a scaffold including a semi-permeable membrane on an outer surface thereof. The present invention also discloses a method of preparing a scaffold covered with a semi- permeable membrane, including loading one or more scaffolds into a mold with a predetermined form and size; and adding a semi-permeable agent and a cross-linking agent to the mold and cross-linking the semi-permeable agent to form the semi-permeable membrane on the outer surface of each of the scaffolds. The scaffold covered with the semi-permeable membrane selectively introduces nutrients into the scaffold by allowing penetration of only external nutrients into the scaffold and excreting metabolic wastes generated by tissue cells to the outside of the scaffold. In addition, the scaffold has the morphology of a biological tissue of interest by cross-linking the small-sized scaffolds, thereby allowing uniform proliferation of tissue cells throughout the whole scaffold.
摘要翻译：披露了在其外表面上包括半透膜的支架。本发明还公开了一种制备覆盖有半透膜的支架的方法，包括将一个或多个支架装载到具有预定形状和尺寸的模具中; 并向模具中加入半渗透剂和交联剂，并交联半渗透剂以在每个支架的外表面上形成半透膜。用半透膜覆盖的支架通过允许将外部营养物渗透到支架中并将组织细胞产生的代谢废物排出到支架的外部，将营养物质选择性地引入支架中。此外，通过交联小尺寸支架，支架具有生物组织的形态，从而允许组织细胞在整个支架中的均匀增殖。

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