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1. 发明公开

EP0772691A4 VECTORS AND TRANSFORMED HOST CELLS FOR RECOMBINANT PROTEIN PRODUCTION AT REDUCED TEMPERATURES 失效
标题翻译：载体和转化的宿主细胞用于重组蛋白生产在降低的温度
公开(公告)号：EP0772691A4
公开(公告)日：1998-05-06
申请号：EP95927215
申请日：1995-07-21
申请人： YISSUM RES DEV CO , LASTER MORRIS C
发明人： OPPENHEIM AMOS B , GILADI HILLA , GOLDENBERG DANIEL , KOBI SIMI , AZAR IDIT
IPC分类号： C12N15/09 , C12N1/21 , C12N15/67 , C12N15/70 , C12P21/00 , C12R1/19 , C12P21/06
CPC分类号： C12N15/67 , C12N15/70

2. 发明申请

WO2012077102A1 IMPLANT CAGE 审中-公开
标题翻译：植入笼
公开(公告)号：WO2012077102A1
公开(公告)日：2012-06-14
申请号：PCT/IL2011/000925
申请日：2011-12-06
申请人： CGM3 LTD. , LASTER, Morris , PHILLIP, Moshe , ELISHA, Yinnon , BYTTON, Rinat
发明人： LASTER, Morris , PHILLIP, Moshe , ELISHA, Yinnon , BYTTON, Rinat
IPC分类号： A61B5/145
CPC分类号： A61B5/686 , A61B5/14503 , A61B5/14532 , A61B5/1473
摘要： The present invention is directed to a rigid implant- protecting and stabilizing device comprising an elongate body perforated by a central bore, wherein said device is of a size and shape such that it is capable of completely or partially containing a sensor element within said central bore. The invention also encompasses methods of implanting sensor elements in a protected environment within bone tissue.
摘要翻译：本发明涉及一种刚性植入物保护和稳定装置，其包括由中心孔穿孔的细长体，其中所述装置具有尺寸和形状，使得其能够在所述中心孔内完全或部分地包含传感器元件。本发明还包括将传感器元件植入骨组织内的受保护环境中的方法。

3. 发明申请

WO2011107988A1 A NON-FOULING NANO-FILTER 审中-公开
标题翻译：一个NON-FOULING NANO-FILTER
公开(公告)号：WO2011107988A1
公开(公告)日：2011-09-09
申请号：PCT/IL2011/000207
申请日：2011-03-01
申请人： CLIL MEDICAL LTD. , ELIACHAR, Eliahu , LASTER, Morris , LILACH, Nir
发明人： ELIACHAR, Eliahu , LASTER, Morris , LILACH, Nir
IPC分类号： B01D63/06 , B01D69/02 , B01D69/04 , B01D69/06 , B01D63/08
CPC分类号： B01D69/02 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0021 , A61F2230/0058 , A61F2230/0069 , A61M2005/1652 , A61M2005/1655 , B01D63/068 , B01D63/087 , B01D69/04 , B01D69/06 , B01D2325/021
摘要： The present invention provides an inherently non-fouling nano-filter characterized by a shape chosen from the group comprising (a) substantially two-dimensional and (b) three-dimensional, said nano-filter comprising a shaped wall, said wall comprising at least one slot-like aperture having a minimal width d and a maximal length L, where d ranges from about 1 nm to 100 nm, L is at least N times larger than d, and N is equal to or greater than 2.
摘要翻译：本发明提供了一种固有的非结垢纳米过滤器，其特征在于选自包括（a）基本上二维和（b）三维所述纳米过滤器的形状，所述纳米过滤器包括成形壁，所述壁至少包括具有最小宽度d和最大长度L的一个狭缝状孔径，其中d的范围为约1nm至100nm，L至少比d大N倍，并且N等于或大于2。

4. 发明申请

WO2008129532A3 DEVICE SYSTEM AND METHOD FOR MONITORING AND CONTROLLING BLOOD ANALYTE LEVELS 审中-公开
标题翻译：用于监测和控制血液分析水平的装置系统和方法
公开(公告)号：WO2008129532A3
公开(公告)日：2010-02-25
申请号：PCT/IL2008000488
申请日：2008-04-09
申请人： C G M 3 LTD , LASTER MORRIS , PHILLIP MOSHE
发明人： LASTER MORRIS , PHILLIP MOSHE
IPC分类号： A61M1/00
CPC分类号： A61B5/6864 , A61B5/0031 , A61B5/14532 , A61B5/1459 , A61B5/1486 , A61B5/14865 , A61B5/417 , A61B5/4504
摘要： A device and system for monitoring an analyte in a subject and for controlling blood analyte levels are provided. The device and system include a sensor element which is designed and configured for detecting the analyte in blood flowing through the bone of the subject.
摘要翻译：提供了用于监测受试者中的分析物并用于控制血液分析物水平的装置和系统。该装置和系统包括传感器元件，其被设计和配置用于检测流过受试者的骨骼的血液中的分析物。

5. 发明申请

WO2003002129A1 USE OF SULODEXIDE FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE 审中-公开
标题翻译：舒必利在治疗炎性肠病中的应用
公开(公告)号：WO2003002129A1
公开(公告)日：2003-01-09
申请号：PCT/IL2002/000384
申请日：2002-05-19
申请人： KERYX BIOPHARMACEUTICALS INC. , SPERO, Michael , SHELACH, Noa , LASTER, Morris
发明人： SPERO, Michael , SHELACH, Noa , LASTER, Morris
IPC分类号： A61K31/715
CPC分类号： A61K31/715 , A61K31/726 , A61K45/06 , A61K2300/00
摘要： The present invention is directed to methods for preventing or treating inflammatory bowel disease by administering a composition comprising a therapeutically or prophylactically effective amount of a composition comprising between about 60% to 90% iduronylglycosaminoglycan sulfate and between about 10% to 40% dermatan sulfate, or a pharmaceutically acceptable salt, solvate, hydrate, or clathrate thereof. In a particular embodiment, a therapeutically or prophylactically effective amount of a composition comprising sulodexide, or a pharmaceutically acceptable salt, solvate, hydrate, or clathrate thereof is administered. The composition to be administered may also comprise one or more additional active ingredients selected from the group consisting of steroids, aminosalicylates, short-chain fatty acids, thioguanine derivatives, antibiotics, biological agents, antidepressants, and pain-relievers.
摘要翻译：本发明涉及预防或治疗炎性肠病的方法，其通过施用包含治疗或预防有效量的组合物的组合物，所述组合物包含约60％至90％的艾杜糖酰基葡糖胺聚糖硫酸盐和约10 ％至40％的硫酸皮肤素，或其药学上可接受的盐，溶剂化物，水合物或包合物。在一个具体的实施方案中，施用治疗或预防有效量的包含舒洛地昔或其药学上可接受的盐，溶剂化物，水合物或包合物的组合物。待施用的组合物还可以包含一种或多种选自类固醇，氨基水杨酸盐，短链脂肪酸，硫鸟嘌呤衍生物，抗生素，生物制剂，抗抑郁药和止痛药的另外的活性成分。

6. 发明申请

WO2002100417A3 USE OF GLYCOSAMINOGLYCANS FOR THE TREATMENT OF HIV-ASSOCIATED NEPHROPATHY 审中-公开
公开(公告)号：WO2002100417A3
公开(公告)日：2002-12-19
申请号：PCT/IL2002/000453
申请日：2002-06-12
申请人： KERYX BIOPHARMACEUTICALS INC. , LASTER, Morris , SHELACH, Noa
发明人： LASTER, Morris , SHELACH, Noa
IPC分类号： A61K31/726
摘要： The present invention concerns a method for the treatment of HIV-associated nephropathy by administration of glycosaminoglycans and in particular by the administration of sulodexide.

7. 发明申请

WO2008129532A2 DEVICE SYSTEM AND METHOD FOR MONITORING AND CONTROLLING BLOOD ANALYTE LEVELS 审中-公开
标题翻译：用于监测和控制血液分析水平的装置系统和方法
公开(公告)号：WO2008129532A2
公开(公告)日：2008-10-30
申请号：PCT/IL2008/000488
申请日：2008-04-09
申请人： MOR RESEARCH APPLICATIONS LTD. , LASTER, Morris , PHILLIP, Moshe
发明人： LASTER, Morris , PHILLIP, Moshe
IPC分类号： A61B5/05
CPC分类号： A61B5/6864 , A61B5/0031 , A61B5/14532 , A61B5/1459 , A61B5/1486 , A61B5/14865 , A61B5/417 , A61B5/4504
摘要： A device and system for monitoring an analyte in a subject and for controlling blood analyte levels are provided. The device and system include a sensor element which is designed and configured for detecting the analyte in blood flowing through the bone of the subject.
摘要翻译：提供了用于监测受试者中的分析物并用于控制血液分析物水平的装置和系统。该装置和系统包括传感器元件，其被设计和配置用于检测流过受试者的骨骼的血液中的分析物。

8. 发明申请

WO1996003521A1 VECTORS AND TRANSFORMED HOST CELLS FOR RECOMBINANT PROTEIN PRODUCTION AT REDUCED TEMPERATURES 审中-公开
标题翻译：降解温度下重组蛋白生产的载体和转化的宿主细胞
公开(公告)号：WO1996003521A1
公开(公告)日：1996-02-08
申请号：PCT/US1995008971
申请日：1995-07-21
申请人： YISSUM RESEARCH AND DEVELOPMENT CO. , LASTER, Morris, C.
发明人： YISSUM RESEARCH AND DEVELOPMENT CO. , LASTER, Morris, C. , OPPENHEIM, Amos, B. , GILADI, Hilla , GOLDENBERG, Daniel , KOBI, Simi , AZAR, Idit
IPC分类号： C12P21/06
CPC分类号： C12N15/67 , C12N15/70
摘要： The invention relates to an expression vector, the nucleic acid sequence of which comprises a promoter that is capable of controlling, when the vector is in a bacterial host and the temperature is lowered to below about 20 DEG C, the production of recombinant peptide or protein encoded by a gene contained within the vector. The invention also relates to host cells containing the vectors and to a method of producing a recombinant protein.
摘要翻译：本发明涉及一种表达载体，其核酸序列包含能够控制当载体在细菌宿主中并且温度降至低于约20℃时的重组肽或蛋白质的产生的启动子由载体内包含的基因编码。本发明还涉及含有载体的宿主细胞和生产重组蛋白的方法。

9. 发明公开

EP0772691A1 VECTORS AND TRANSFORMED HOST CELLS FOR RECOMBINANT PROTEIN PRODUCTION AT REDUCED TEMPERATURES 失效
标题翻译：载体和转化的宿主细胞用于重组蛋白生产在降低的温度
公开(公告)号：EP0772691A1
公开(公告)日：1997-05-14
申请号：EP95927215.0
申请日：1995-07-21
申请人： YISSUM RESEARCH AND DEVELOPMENT CO. , Laster, Morris C.
发明人： OPPENHEIM, Amos B. , GILADI, Hilla , GOLDENBERG, Daniel , KOBI, Simi , AZAR, Idit
IPC分类号： C12N15 , C12N1 , C12P21 , C12R1
CPC分类号： C12N15/67 , C12N15/70
摘要： The invention relates to an expression vector, the nucleic acid sequence of which comprises a promoter that is capable of controlling, when the vector is in a bacterial host and the temperature is lowered to below about 20 °C, the production of recombinant peptide or protein encoded by a gene contained within the vector. The invention also relates to host cells containing the vectors and to a method of producing a recombinant protein.

10. 发明公开

EP0969775A1 BONE MARROW AS A SITE FOR TRANSPLANTATION 失效
标题翻译：骨髓移植物网站
公开(公告)号：EP0969775A1
公开(公告)日：2000-01-12
申请号：EP98914301.1
申请日：1998-03-25
申请人： Laster, Morris , Rosenwald, Lindsay
发明人： Laster, Morris , Rosenwald, Lindsay
IPC分类号： A61B19/00
CPC分类号： A61K9/0085 , A61B90/00 , A61B2010/0258 , A61B2017/00969
摘要： The invention relates to a process for culturing cells by introducing the cells into the bone or bone marrow of a mammal. The invention also relates to a method for delivering a biologically active substance, including a nucleic acid, vector, protein or pharmaceutical composition to a mammal by introducing the substance into the bone or bone marrow.

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