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1. 发明专利

IL201309D0 NOVEL N - (8 - HETEROARYLTETRAHYDRONAPHTALENE - 2YL) OR N - (5 - HETEROARYLCHROMANE - 3 - YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN 未知
公开(公告)号：IL201309D0
公开(公告)日：2010-05-31
申请号：IL20130909
申请日：2009-10-01
申请人： ASTRAZENECA AB , YEVGENI BESIDSKI , INGER KERS , MARTIN NYLOF , LARS SANDBERG , KARIN SKOGHOLM
IPC分类号： C07D20100101
摘要： The present invention relates to new compounds of formula (I) and to pharmaceutical composition containing said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof.

2. 发明专利

SE9602323D0 未知
公开(公告)号：SE9602323D0
公开(公告)日：1996-06-12
申请号：SE9602323
申请日：1996-06-12
申请人： LARS SANDBERG , JAN OLOF STAALBERG
发明人： SANDBERG LARS , STAALBERG JAN OLOF
IPC分类号： H01R20060101 , H01R27/02 , H01R31/06 , H01R

3. 发明专利

SE9602323L 未知
公开(公告)号：SE9602323L
公开(公告)日：1997-12-13
申请号：SE9602323
申请日：1996-06-12
申请人： LARS SANDBERG , JAN OLOF STAALBERG
发明人： SANDBERG LARS , STAALBERG JAN OLOF
IPC分类号： H01R20060101 , H01R27/02 , H01R31/06

4. 发明申请

US20130345247A1 Cyclohexane-1,2'-Indene-1',2"-Imidazol Compounds and Their Use as Bace Inhibitors 有权
标题翻译：环己烷-1,2'-茚-1'，2“ - 咪唑化合物及其作为阻止剂的用途
公开(公告)号：US20130345247A1
公开(公告)日：2013-12-26
申请号：US13916701
申请日：2013-06-13
申请人： Sofia Karlstrom , Peter Soderman , Laszlo Rakos , Liselotte Ohberg , Karin Kolmodin , Lars Sandberg
发明人： Sofia Karlstrom , Peter Soderman , Laszlo Rakos , Liselotte Ohberg , Karin Kolmodin , Lars Sandberg
IPC分类号： C07D235/02 , A61K45/06 , A61K31/4439 , A61K31/4184 , C07D401/04
CPC分类号： C07D235/02 , A61K31/4184 , A61K31/4439 , A61K45/06 , C07D401/02 , C07D401/04
摘要： Cyclohexane-1,2′-indene-1′,2″-imidazole compounds, therapeutically acceptable salts thereof, processes for preparation thereof, therapeutic uses of such compounds for treating Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy, Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration, methods of therapy using such compounds, and pharmaceutical compositions containing such compounds.
摘要翻译：环己烷-1,2'-茚-1'，2“ - 咪唑化合物，其治疗上可接受的盐，其制备方法，这些化合物治疗Abeta相关病症如唐氏综合征，β-淀粉样血管病，阿尔茨海默病，记忆丧失，与阿尔茨海默病相关的注意力缺陷症状，与诸如阿尔茨海默病或痴呆的疾病相关的神经变性，包括混合血管和退行性起源的痴呆，老年痴呆，老年痴呆和与帕金森病相关的痴呆，进行性核上性麻痹或皮层基底变性，使用这些化合物的治疗方法，以及含有这些化合物的药物组合物。

5. 发明授权

US08584833B2 Oscillating conveyor 有权
标题翻译：摆动输送机
公开(公告)号：US08584833B2
公开(公告)日：2013-11-19
申请号：US13508161
申请日：2010-11-10
申请人： Lars Sandberg
发明人： Lars Sandberg
IPC分类号： B65G25/00
CPC分类号： B65G27/12 , B65G27/18 , B65G27/32
摘要： An oscillating conveyor includes a support, a conveying element arranged to carry objects to be moved and supported by the support in order to be displaced between a first extreme position and a second extreme position, and a driving device to displace the conveying element. The driving device includes a crank mechanism, which includes a pendulum pin, which in relation to a rotational axis of the crank mechanism is mounted such that, when the crank rotates, at the pendulum pin an angle between the axis of rotation and a first pivot pin varies within an angular range being either obtuse or acute, resulting in the desired displacement of the conveying element at different speeds, the position of the pendulum pin in relation to the rotational axis being adjustable to vary the displacement speed of the conveyor element.
摘要翻译：振荡输送机包括支撑件，输送元件，其被布置成承载要由所述支撑件移动和支撑的物体，以便在第一极限位置和第二极限位置之间移动;以及驱动装置，用于移动所述输送元件。该驱动装置包括一个曲柄机构，该曲柄机构包括一个摆动销，该摆杆相对于曲柄机构的旋转轴线被安装成使得当曲柄转动时，摆锤在旋转轴线与第一枢轴销在钝角或锐角的角度范围内变化，导致输送元件在不同速度下的期望位移，摆动销相对于旋转轴线的位置是可调节的，以改变输送元件的移动速度。

6. 发明授权

US08415483B2 Compounds and their use as BACE inhibitors 有权
标题翻译：化合物及其作为BACE抑制剂的用途
公开(公告)号：US08415483B2
公开(公告)日：2013-04-09
申请号：US13331284
申请日：2011-12-20
申请人： Gabor Csjernyik , Sofia Karlström , Annika Kers , Karin Kolmodin , Martin Nylöf , Liselotte Öhberg , Laszlo Rakos , Lars Sandberg , Fernando Sehgelmeble , Peter Söderman , Britt-Marie Swahn , Stefan Von Berg
发明人： Gabor Csjernyik , Sofia Karlström , Annika Kers , Karin Kolmodin , Martin Nylöf , Liselotte Öhberg , Laszlo Rakos , Lars Sandberg , Fernando Sehgelmeble , Peter Söderman , Britt-Marie Swahn , Stefan Von Berg
IPC分类号： A61K31/4184 , C07D235/02 , A61K31/4439
CPC分类号： A61K31/497 , A61K31/4184 , A61K31/4188 , A61K31/437 , A61K31/4439 , A61K31/506 , A61K45/06 , A61K2300/00 , C07D235/02 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D471/04 , C07D491/107 , C07D491/20
摘要： The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.
摘要翻译：本发明涉及式（I）化合物及其药物组合物。此外，本发明涉及用于治疗和/或预防与疾病相关的病症如唐氏综合征和淀粉样血管病变的治疗方法，例如但不限于脑淀粉样血管病或遗传性脑出血，与认知障碍，例如但不限于MCI（轻度认知障碍），阿尔茨海默病，记忆丧失，与阿尔茨海默病相关的注意力缺陷症状，与诸如阿尔茨海默氏病或痴呆的疾病相关的神经变性，包括混合血管和退行性来源的痴呆，老年性痴呆，老年性痴呆和与帕金森病相关的痴呆，进行性核上性麻痹或皮质基底变性。

7. 发明申请

US20120234654A1 OSCILLATING CONVEYOR 有权
标题翻译：振荡输送机
公开(公告)号：US20120234654A1
公开(公告)日：2012-09-20
申请号：US13508161
申请日：2010-11-10
申请人： Lars Sandberg
发明人： Lars Sandberg
IPC分类号： B65G25/04
CPC分类号： B65G27/12 , B65G27/18 , B65G27/32
摘要： An oscillating conveyor includes a support, a conveying element arranged to carry objects to be moved and supported by the support in order to be displaced between a first extreme position and a second extreme position, and a driving device to displace the conveying element. The driving device includes a crank mechanism, which includes a pendulum pin, which in relation to a rotational axis of the crank mechanism is mounted such that, when the crank rotates, at the pendulum pin an angle between the axis of rotation and a first pivot pin varies within an angular range being either obtuse or acute, resulting in the desired displacement of the conveying element at different speeds, the position of the pendulum pin in relation to the rotational axis being adjustable to vary the displacement speed of the conveyor element.
摘要翻译：振荡输送机包括支撑件，输送元件，其被布置成承载要由所述支撑件移动和支撑的物体，以便在第一极限位置和第二极限位置之间移动;以及驱动装置，用于移动所述输送元件。该驱动装置包括一个曲柄机构，该曲柄机构包括一个摆动销，该摆杆相对于曲柄机构的旋转轴线被安装成使得当曲柄转动时，摆锤在旋转轴线与第一枢轴销在钝角或锐角的角度范围内变化，导致输送元件在不同速度下的期望位移，摆动销相对于旋转轴线的位置是可调节的，以改变输送元件的移动速度。

8. 发明授权

US08264335B2 Device attached to a blister 有权
标题翻译：设备连接到水泡
公开(公告)号：US08264335B2
公开(公告)日：2012-09-11
申请号：US12520393
申请日：2007-12-19
申请人： Marcus Dehlin , Lars Sandberg , Ingrid Rokahr
发明人： Marcus Dehlin , Lars Sandberg , Ingrid Rokahr
IPC分类号： G08B1/00 , G08B23/00 , G07F11/00
CPC分类号： A61J7/0481 , A61J1/035 , A61J7/0418 , A61J7/0436 , A61J2200/30 , A61J2200/70 , A61J2205/20 , A61J2205/70
摘要： A device adapted to be releasable attached to a blister including at least one piece of medicament. The device includes apparatus for releasable attachment to the blister, a sensor arrangement including at least one first sensor arranged to register the sound of the dispense of a piece of medicament, a time system arranged to register the time and/or date of the dispensing of said piece of medicament and a memory for storing data, such as time and/or date data, related to the dispense of the piece of medicament.
摘要翻译：适于可释放地附接到包括至少一片药物的泡罩的装置。该装置包括用于可释放地附接到泡罩的装置，传感器装置，其包括至少一个第一传感器，其布置成对一片药物的分配声音进行记录;布置成记录分配的时间和/或日期的时间系统所述药物片和用于存储数据的存储器，例如时间和/或日期数据，与药物分配有关。

9. 发明申请

US20120165347A1 Compounds and their use as BACE Inhibitors 有权
标题翻译：化合物及其作为BACE抑制剂的用途
公开(公告)号：US20120165347A1
公开(公告)日：2012-06-28
申请号：US13331284
申请日：2011-12-20
申请人： Gabor Csjernyik , Sofia Karlström , Annika Kers , Karin Kolmodin , Martin Nylöf , Liselotte Öhberg , Laszlo Rakos , Lars Sandberg , Fernando Sehgelmeble , Peter Söderman , Britt-Marie Swahn , Stefan Von Berg
发明人： Gabor Csjernyik , Sofia Karlström , Annika Kers , Karin Kolmodin , Martin Nylöf , Liselotte Öhberg , Laszlo Rakos , Lars Sandberg , Fernando Sehgelmeble , Peter Söderman , Britt-Marie Swahn , Stefan Von Berg
IPC分类号： A61K31/506 , A61K31/437 , A61K31/4164 , A61K31/4188 , C07D403/12 , C07D401/10 , C07D471/04 , C07D235/02 , C07D491/107 , C07D409/14 , A61P25/28 , A61P25/16 , A61P25/00 , C07D405/14 , A61K31/4439
CPC分类号： A61K31/497 , A61K31/4184 , A61K31/4188 , A61K31/437 , A61K31/4439 , A61K31/506 , A61K45/06 , A61K2300/00 , C07D235/02 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D471/04 , C07D491/107 , C07D491/20
摘要： The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.
摘要翻译：本发明涉及式（I）化合物及其药物组合物。此外，本发明涉及用于治疗和/或预防与疾病相关的病症如唐氏综合征和淀粉样血管病变的治疗方法，例如但不限于脑淀粉样血管病或遗传性脑出血，与认知障碍，例如但不限于MCI（“轻度认知障碍”），阿尔茨海默病，记忆丧失，与阿尔茨海默病相关的注意力缺陷症状，与诸如阿尔茨海默氏病或痴呆症的疾病相关的神经变性，包括混合血管和退行性来源的痴呆，老年性痴呆，老年性痴呆和与帕金森病相关的痴呆，进行性核上性麻痹或皮质基底变性。

10. 发明申请

US20100094455A1 DEVICE ATTACHED TO A BLISTER 有权
标题翻译：设备连接到发泡器
公开(公告)号：US20100094455A1
公开(公告)日：2010-04-15
申请号：US12520393
申请日：2007-12-19
申请人： Marcus Dehlin , Lars Sandberg , Ingrid Rokahr
发明人： Marcus Dehlin , Lars Sandberg , Ingrid Rokahr
IPC分类号： G06F17/00 , G08B21/00
CPC分类号： A61J7/0481 , A61J1/035 , A61J7/0418 , A61J7/0436 , A61J2200/30 , A61J2200/70 , A61J2205/20 , A61J2205/70
摘要： The present invention concerns a device (14) adapted to be releasable attached to a blister (10) including at least one piece of medicament (13). The device (14) comprises means for releasable attachment to said blister (10) a sensor arrangement including at least one first sensor arranged to register the sound of the dispense of a piece of medicament (13), a time system arranged to register the time and/or date of the dispensing of said piece of medicament (13) and a memory for storing data, such as time and/or date data, related to the dispense of said piece of medicament.
摘要翻译：本发明涉及适于可释放地附接到包括至少一片药物（13）的泡罩（10）的装置（14）。装置（14）包括用于可释放地附接到所述泡罩（10）的装置，传感器装置包括至少一个第一传感器，所述至少一个第一传感器被布置成记录一片药物（13）的分配声音，布置成记录时间和/或分配所述药片（13）的日期和用于存储与分配所述药片相关的数据的存储器，例如时间和/或日期数据。

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