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1. 发明专利

IL174464A Use of antisecretory factor in the preparation of a medicament 未知
公开(公告)号：IL174464A
公开(公告)日：2015-08-31
申请号：IL17446406
申请日：2006-03-21
申请人： FAKTOR AB AS , HANSSON HANS-ARNE , LANGE STEFAN , ERIKSSON PETER , JENNISCHE EVA , LONNROTH IVAR , PERSSON ANDERS
发明人： HANSSON HANS-ARNE , LANGE STEFAN , ERIKSSON PETER , JENNISCHE EVA , LONNROTH IVAR , PERSSON ANDERS
IPC分类号： A61K20060101 , A23L33/00 , A61K38/17 , A61P20060101 , C07K20060101
摘要： The present invention relates to the use of an antisecretory protein or homologues thereof having the same properties, or certain fragments thereof in the manufacture of a medicament or a medical food for inducing improved rescue of injured or diseased nervous tissue, proliferation, apoptosis, differentiation and/or migration of an embryonic stem cell, adult stem cell, progenitor cell and/or a cell derived from a stem cell or progenitor cell, for treating a condition characterized by or associated with loss and/or gain of cells. In a preferred embodiment, the condition is a neurotrauma or a condition or disease of the CNS and/or PNS and/or ANS, for example, Alzheimer's disease.

2. 发明专利

IL174464D0 NOVEL USE OF ANTISECRETORY FACTOR 未知
公开(公告)号：IL174464D0
公开(公告)日：2006-08-01
申请号：IL17446406
申请日：2006-03-21
申请人： FAKTOR AB AS , HANSSON HANS ARNE , LANGE STEFAN , ERIKSSON PETER , JENNISCHE EVA , LONNROTH IVAR , PERSSON ANDERS
IPC分类号： A23L33/00 , A61K20100101 , A61K38/17
摘要： The present invention relates to the use of an antisecretory protein or homologues thereof having the same properties, or certain fragments thereof in the manufacture of a medicament or a medical food for inducing improved rescue of injured or diseased nervous tissue, proliferation, apoptosis, differentiation and/or migration of an embryonic stem cell, adult stem cell, progenitor cell and/or a cell derived from a stem cell or progenitor cell, for treating a condition characterized by or associated with loss and/or gain of cells. In a preferred embodiment, the condition is a neurotrauma or a condition or disease of the CNS and/or PNS and/or ANS, for example, Alzheimer's disease.

3. 发明申请

WO2012049015A2 LICHTSYSTEM MIT ERHÖHTER EFFIZIENZ 审中-公开
标题翻译：以更高的效率灯光系统
公开(公告)号：WO2012049015A2
公开(公告)日：2012-04-19
申请号：PCT/EP2011/066724
申请日：2011-09-27
申请人： OSRAM AG , BERBEN, Dirk , FRISCHEISEN, Joerg , JERMANN, Frank , LANGE, Stefan
发明人： BERBEN, Dirk , FRISCHEISEN, Joerg , JERMANN, Frank , LANGE, Stefan
IPC分类号： F21K99/00
CPC分类号： F21V9/30 , F21K9/232 , F21K9/62 , F21K9/64 , F21Y2113/13 , F21Y2115/10 , H01L25/0753 , H01L33/50 , H01L2924/0002 , H01L2924/00
摘要： Ein Lichtsystem mit erhöhter Effizienz auf Basis einer beabstandeten konvertierenden Schicht weist mindestens zwei verschiedene Arten von Chips auf, wobei die Strahlung einer ersten Art von Chips von der Konversionsschicht zumindest teilweise konvertiert wird. Die Strahlung der zweiten Art von Chip ist längerwellig als die der ersten Chips, wobei die zweiten Chips so angeordnet sind, dass ihre Strahlung im wesentlichen nicht vom Leuchtstoff absorbiert wird.
摘要翻译：有间隔开的转换层的基础上改进的效率的光学系统包括至少两个不同类型的芯片，其中，所述第一类型的芯片的辐射由转换层至少部分地转化。所述第二类型的芯片的辐射比第一芯片的较长波长，第二芯片被布置为使得它们的辐射基本上不被所述磷光体吸收。

4. 发明申请

WO2007126365A3 FURTHER MEDICAL USES OF ANTISECRETORY PROTEIN 审中-公开
标题翻译：抗体蛋白的进一步医学用途
公开(公告)号：WO2007126365A3
公开(公告)日：2008-03-13
申请号：PCT/SE2007000415
申请日：2007-04-27
申请人： LANTMAENNEN AS FAKTOR , HANSSON HANS-ARNE , LANGE STEFAN
发明人： HANSSON HANS-ARNE
IPC分类号： A61K38/17 , A61P3/10 , A61P7/00 , A61P9/00 , A61P17/00 , A61P35/00
CPC分类号： A61K38/1709 , A61K38/08
摘要： The present invention relates to the use of an antisecretory protein, derivative, homologue, and/or fragment thereof, having equivalent activity, and/or a pharmaceutically active salt thereof, for the manufacture of a pharmaceutical composition and/or a medical food for the treatment and/or prevention of dysfunction, e.g. abnormal function, hypo-orhyper-function of lipid rafts, receptors and/or caveolae. A dysfunction of lipid rafts, receptors and/or caveolae may be caused by or be a cause of a variety of other conditions, which are also encompassed by the present invention, such as vascular, and lung dysfunctions, and/or endocrine disorders, e.g. diabetes and related disorders. Furthermore, the invention relates to a method for the treatment and/or prevention of dysfunction of lipid rafts and/or caveolae in a mammal in need thereof.
摘要翻译：本发明涉及具有相同活性的抗分泌蛋白，其衍生物，同系物和/或其片段，和/或其药学活性盐在制备药物组合物和/或用于治疗和/或预防功能障碍，例如异常功能，脂筏，受体和/或穴状病毒的低或高功能。脂质筏，受体和/或穴状窝蛋白的功能障碍可能是由本发明也包括在内的多种其它病症的原因引起的，例如血管和肺功能障碍，和/或内分泌紊乱，例如内分泌障碍。糖尿病和相关疾病。此外，本发明涉及在有需要的哺乳动物中治疗和/或预防脂筏和/或小窝病的功能障碍的方法。

5. 发明申请

WO2007126364A3 USE OF ANTISECRETORY FACTORS FOR TREATING INTRAOCULAR HYPERTENSION 审中-公开
标题翻译：使用抗心律失常因子治疗高血压
公开(公告)号：WO2007126364A3
公开(公告)日：2008-03-06
申请号：PCT/SE2007000414
申请日：2007-04-27
申请人： LANTMAENNEN AS FAKTOR , HANSSON HANS-ARNE , LANGE STEFAN , JENNISCHE EVA
发明人： HANSSON HANS-ARNE , LANGE STEFAN , JENNISCHE EVA
IPC分类号： A61K38/17 , A61P27/02
CPC分类号： A61K38/1709
摘要： The present invention relates to the use of antisecretory factors, such as antisecretory proteins, homologues, derivatives and/or fragments thereof having antisecretory activity, for the manufacture of a pharmaceutical composition for use in the treatment and/or prevention of intraocular hypertension. The invention thus relates to the use of pharmaceutical compositions comprising antisecretory factors in the treatment and/or prevention of intraocular hypertension, which is preferably characterized by hampered outflow of body fluid resulting in elevated pressure in the eye. The invention provides for a novel approach for treating and/or preventing such a condition turning the intraocular pressure to an acceptable level, optionally 21 mm Hg, or less.
摘要翻译：本发明涉及具有抗分泌活性的抗分泌蛋白，同系物，衍生物和/或片段等抗分泌因子在制备用于治疗和/或预防眼内高血压的药物组合物中的应用。因此，本发明涉及包含抗分泌因子的药物组合物在治疗和/或预防眼内高血压中的用途，其优选特征在于体液流出受阻，导致眼压升高。本发明提供了一种用于治疗和/或预防这种将眼内压转换成可接受水平（任选地21mm Hg或更小）的病症的新方法。

6. 发明申请

WO2007126365A8 FURTHER MEDICAL USES OF ANTISECRETORY PROTEIN 审中-公开
公开(公告)号：WO2007126365A8
公开(公告)日：2007-11-08
申请号：PCT/SE2007/000415
申请日：2007-04-27
申请人： LANTMÄNNEN AS-FAKTOR AB , HANSSON, Hans-Arne , LANGE, Stefan
发明人： HANSSON, Hans-Arne , LANGE, Stefan
IPC分类号： A61K38/17 , A61P3/10 , A61P7/00 , A61P9/00 , A61P17/00 , A61P35/00
摘要： The present invention relates to the use of an antisecretory protein, derivative, homologue, and/or fragment thereof, having equivalent activity, and/or a pharmaceutically active salt thereof, for the manufacture of a pharmaceutical composition and/or a medical food for the treatment and/or prevention of dysfunction, e.g. abnormal function, hypo-orhyper-function of lipid rafts, receptors and/or caveolae. A dysfunction of lipid rafts, receptors and/or caveolae may be caused by or be a cause of a variety of other conditions, which are also encompassed by the present invention, such as vascular, and lung dysfunctions, and/or endocrine disorders, e.g. diabetes and related disorders. Furthermore, the invention relates to a method for the treatment and/or prevention of dysfunction of lipid rafts and/or caveolae in a mammal in need thereof.

7. 发明申请

WO2007126363A3 ANTISECRETORY PROTEIN FOR USE IN THE TREATMENT OF COMPARTMENT SYNDROME 审中-公开
公开(公告)号：WO2007126363A3
公开(公告)日：2007-11-08
申请号：PCT/SE2007/000413
申请日：2007-04-27
申请人： LANTMÅNNEN AS-FAKTOR , HANSSON, Hans-Arne , LANGE, Stefan , JENNISCHE, Eva , BERGSTRÖM, Tomas
发明人： HANSSON, Hans-Arne , LANGE, Stefan , JENNISCHE, Eva , BERGSTRÖM, Tomas
IPC分类号： A61K38/17 , A61P43/00 , A61P19/00
摘要： The present invention relates to the use of an antisecretory protein or a derivative, homologue, and/or fragment thereof, having antisecretory activity, and/or a pharmaceutically active salt thereof, for the manufacture of a pharmaceutical composition and/or a medical food for the treatment and/or prevention of compartment syndrome. A compartment syndrome may be caused by or a cause of a variety of other conditions which are also encompassed by the present invention, such as viral and bacterial infections. Furthermore, the invention relates to a method for the treatment and/or prevention of compartment syndrome in a mammal in need thereof.

8. 发明申请

WO0248322A3 RECOMBINANT PORCINE LIVER ESTERASES, THEIR USE AND A METHOD FOR THE PRODUCTION THEREOF 审中-公开
标题翻译：重组猪肉表面，它们的用途及其生产方法
公开(公告)号：WO0248322A3
公开(公告)日：2002-12-12
申请号：PCT/EP0114338
申请日：2001-12-06
申请人： DEGUSSA , BORNSCHEUER UWE , MUSIDLOWSKA ANNA , SCHMIDT-DANNERT CLAUDIA , LANGE STEFAN
发明人： BORNSCHEUER UWE , MUSIDLOWSKA ANNA , SCHMIDT-DANNERT CLAUDIA , LANGE STEFAN
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/18 , C12N9/20 , C12N15/55 , C12P41/00 , C12N15/62 , C12P7/02 , C12P7/42
CPC分类号： C12N9/18
摘要： The invention relates to biotechnologically expressible, enzymatically active recombinant porcine liver esterases, to a biotechnological method for the production thereof, and to their use in organic synthesis. The monomeric subunits of the recombinant porcine liver esterase are shortened at the C-terminal end compared to the subunits of naturally occurring porcine liver esterase. In addition, it has been proven advantageous to shorten the N-terminal end as well.
摘要翻译：本发明涉及生物技术可表达的酶促活性重组猪肝酯酶，其制备的生物技术方法及其在有机合成中的用途。与天然存在的猪肝酯酶亚基相比，重组猪肝酯酶的单体亚基在C-末端被截短。此外，证明还有利于缩短N-末端。

9. 发明申请

WO2013053601A3 OPTOELEKTRONISCHES BAUELEMENT UND LEUCHTSTOFFE 审中-公开
公开(公告)号：WO2013053601A3
公开(公告)日：2013-04-18
申请号：PCT/EP2012/069003
申请日：2012-09-26
申请人： OSRAM OPTO SEMICONDUCTORS GMBH , BAUMGARTNER, Alexander , JERMANN, Frank , LANGE, Stefan , FIEDLER, Tim
发明人： BAUMGARTNER, Alexander , JERMANN, Frank , LANGE, Stefan , FIEDLER, Tim
IPC分类号： C09K11/77 , H05B33/14
摘要： Ein optoelektronisches Bauelement umfasst eine Schichtenfolge (1) mit einem aktiven Bereich, der elektromagnetische Primärstrahlung emittiert und ein Konversionsmaterial, das im Strahlengang der elektromagnetischen Primärstrahlung angeordnet ist und zumindest teilweise die elektromagnetische Primärstrahlung in eine elektromagnetische Sekundärstrahlung konvertiert. Das Konversionsmaterial umfasst einen ersten Leuchtstoff (6- 1) mit der allgemeinen Zusammensetzung A 3 B 5 O 12 , wobei A aus einer Gruppe ausgewählt ist, die Y, Lu, Gd und Ce und Kombinationen daraus umfasst, und wobei B eine Kombination aus Al und Ga umfasst; und einen zweiten Leuchtstoff (6-2), der aus einer Gruppe ausgewählt ist, die M 1 AlSiN 3 •Si 2 N 2 O, M 3 AlSiN 3 , M 4 -Al-Si-N System, M 5 -Al-Si-N System und M 2 Si 5 N 8 umfasst, wobei M eine Kombination aus Ca, Sr, Ba und Eu umfasst, M 1 aus einer Gruppe ausgewählt ist, die Sr, Ca, Mg, Li, Eu und Kombinationen daraus umfasst, M 3 aus eine Gruppe ausgewählt ist, die Sr, Ca, Mg, Li, Eu und Kombinationen daraus umfasst, M 4 zumindest Ca und M 5 zumindest Ca oder Ba oder Sr umfasst.

10. 发明申请

WO2013053601A2 OPTOELECTRONIC COMPONENT AND LUMINESCENT SUBSTANCES 审中-公开
标题翻译：光电子器件和光面料
公开(公告)号：WO2013053601A2
公开(公告)日：2013-04-18
申请号：PCT/EP2012069003
申请日：2012-09-26
申请人： OSRAM OPTO SEMICONDUCTORS GMBH , BAUMGARTNER ALEXANDER , JERMANN FRANK , LANGE STEFAN , FIEDLER TIM
发明人： BAUMGARTNER ALEXANDER , JERMANN FRANK , LANGE STEFAN , FIEDLER TIM
IPC分类号： C09K11/77 , H05B33/14
CPC分类号： C09K11/7728 , C09K11/7734 , C09K11/7774 , H01L33/504 , H01L2224/32245 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2924/12044 , H01L2924/00014 , H01L2924/00
摘要： The invention relates to an optoelectronic component comprising a layer sequence (1), which has an active region that emits electromagnetic primary radiation, and a conversion material, which is arranged in the beam path of the electromagnetic primary radiation and at least partially converts the electromagnetic primary radiation into an electromagnetic secondary radiation. The conversion material comprises a first luminescent substance (6-1) having the general composition A3B5O12, wherein A is selected from a group comprising Y, Lu, Gd, and CE and combinations thereof, and wherein B comprises a combination of Al and Ga; and a second luminescent substance (6-2), which is selected from a group comprising M1AlSiN3.Si2N2O, M3AlSiN3, M4-Al-Si-N system, M5-Al-Si-N system, and M2Si5N8, wherein M comprises a combination of Ca, Sr, Ba, and Eu, M1 is selected from a group comprising Sr, Ca, Mg, Li, Eu, and combinations thereof, M3 is selected from a group comprising Sr, Ca, Mg, Li, Eu, and combinations thereof, and M4 comprises at least Ca, and M5 comprises at least Ca or Ba or Sr.
摘要翻译：的光电元件，其包括具有发射电磁初级辐射的有源区的层序列（1），和一个转换材料，其被布置在所述电磁初级辐射的光束路径和至少部分地转换电磁初级辐射为电磁次级辐射。所述转换材料包括第一磷光体（6- 1）一般组成A3B5O12，其中A选自包括Y，路，Gd和Ce和它们的组合，并且其中B包含Al和Ga的组合的组中选择; 和第二荧光体（6-2），它是从一组M1AlSiN3.Si2N2O，M3AlSiN3，M4-Al-Si系-N系统，M5-Al-Si系-N系统和M2Si5N8，其中M是一个组合中选择包括钙，锶，钡及Eu，M1是从由Sr中的基团，钙，镁，锂，Eu和它们的组合，M3是从一组锶，钙，镁，锂，Eu和组合组成的组包括从中，M4包括至少Ca和M5至少Ca或Ba或高级

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