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    • 5. 发明授权
    • Method of agitating solution
    • 搅拌方法
    • US08298832B2
    • 2012-10-30
    • US10593680
    • 2005-03-17
    • Yuki TakiiKunihisa NaginoFumio NakamuraHitoshi Nobumasa
    • Yuki TakiiKunihisa NaginoFumio NakamuraHitoshi Nobumasa
    • G01N1/00C12Q1/00C12Q1/68B01F11/00
    • B01F13/0059B01F13/0052B01F13/0054B01F13/02G01N2035/00158G01N2035/00544Y10T436/25
    • The method of stirring a solution according to the present invention is a method of stirring a solution comprising contacting a selective binding substance immobilized on the surface of a carrier with a solution containing an analyte substance reactive with the selective binding substance, and mixing the fine particles or air bubbles into the solution containing an analyte substance, and moving the fine particles or air bubbles without allowing contact thereof with the selective binding substance-immobilized surface.The present invention provides a stirring method that accelerates the reaction of a carrier-immobilized selective binding substance with an analyte substance and detects a trace amount of analyte at high signal intensity and high S/N ratio.The present invention enables diagnosis and examination in the clinical setting by using a selective binding substance-immobilized carrier such as DNA chip.
    • 根据本发明的搅拌溶液的方法是一种搅拌溶液的方法,其包括将固定在载体表面上的选择性结合物质与含有与选择性结合物质反应的分析物质的溶液接触,并将微粒子 或气泡进入含有分析物质的溶液中,并且移动细颗粒或气泡,而不允许其与选择性结合物质固定的表面接触。 本发明提供了一种加速载体固定的选择性结合物质与分析物质的反应并在高信号强度和高S / N比下检测微量分析物的搅拌方法。 本发明通过使用选择性结合物质固定载体如DNA芯片,能够在临床环境中进行诊断和检查。
    • 7. 发明申请
    • Method of agitating solution
    • 搅拌方法
    • US20070178603A1
    • 2007-08-02
    • US10593680
    • 2005-03-17
    • Yuki TakiiKunihisa NaginoFumio NakamuraHitoshi Nobumasa
    • Yuki TakiiKunihisa NaginoFumio NakamuraHitoshi Nobumasa
    • G01N1/00
    • B01F13/0059B01F13/0052B01F13/0054B01F13/02G01N2035/00158G01N2035/00544Y10T436/25
    • The method of stirring a solution according to the present invention is a method of stirring a solution comprising contacting a selective binding substance immobilized on the surface of a carrier with a solution containing an analyte substance reactive with the selective binding substance, and mixing the fine particles or air bubbles into the solution containing an analyte substance, and moving the fine particles or air bubbles without allowing contact thereof with the selective binding substance-immobilized surface. The present invention provides a stirring method that accelerates the reaction of a carrier-immobilized selective binding substance with an analyte substance and detects a trace amount of analyte at high signal intensity and high S/N ratio. The present invention enables diagnosis and examination in the clinical setting by using a selective binding substance-immobilized carrier such as DNA chip.
    • 根据本发明的搅拌溶液的方法是一种搅拌溶液的方法,其包括将固定在载体表面上的选择性结合物质与含有与选择性结合物质反应的分析物质的溶液接触,并将微粒子 或气泡进入含有分析物质的溶液中,并且移动细颗粒或气泡,而不允许其与选择性结合物质固定的表面接触。 本发明提供了一种加速载体固定的选择性结合物质与分析物质的反应并在高信号强度和高S / N比下检测微量分析物的搅拌方法。 本发明通过使用选择性结合物质固定载体如DNA芯片,能够在临床环境中进行诊断和检查。