专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07122602B2 Process of making polymeric hydrogels by reactive extrusion 有权
标题翻译：通过反应性挤出制备聚合物水凝胶的方法
公开(公告)号：US07122602B2
公开(公告)日：2006-10-17
申请号：US10801232
申请日：2004-03-16
申请人： Krystyna Plochocka , Timothy G. Bee
发明人： Krystyna Plochocka , Timothy G. Bee
IPC分类号： A61K47/30 , A61K47/38 , C08F8/28
CPC分类号： C08L73/02 , A61L15/585 , C08F8/14 , C08F261/04 , C08F261/06 , C08F265/02 , C08F283/00 , C08F2810/20 , C08L71/02 , C08L2205/05 , C08L35/00 , C08L2666/04 , C08F222/06
摘要： What is described is a reactive extrusion process of making a polymeric hydrogel of a polymeric anhydride or acid, e.g. maleic anhydride or maleic acid polymer, or copolymer thereof, crosslinked with a crosslinking agent containing at least 2 crosslinkable groups, particularly, —OH or —NH2, or both. The reaction product is a crosslinked polymeric ester or amide/imide, or both, suitably having a mole ratio of —OH, or —NH2, to —COOH, of 1:10 to 10:1, preferably 2:10 to 7:1. The hydrogel is particularly swellable in water, e.g. >100% in 1 hour in aqueous media; and forms a thin, tacky layer on a substrate, which property is useful in bioadhesive products.
摘要翻译：所描述的是制备聚合物酐或酸的聚合物水凝胶的反应挤出方法，例如。马来酸酐或马来酸聚合物或其共聚物与含有至少2个可交联基团，特别是-OH或-NH 2或两者的交联剂交联。反应产物是交联的聚合酯或酰胺/酰亚胺，或两者，适当地具有1:10至10:1的-OH或-NH 2，-COOH的摩尔比，优选为2:10至7:1。水凝胶在水中特别溶胀，例如在水介质中1小时内> 100％并且在基底上形成薄的粘性层，该性质在生物粘附产品中是有用的。

2. 发明授权

US06300442B1 Process for making a cosmetically or pharmaceutically-acceptable emulsion or gel composition 失效
标题翻译：制备美容或药学上可接受的乳液或凝胶组合物的方法
公开(公告)号：US06300442B1
公开(公告)日：2001-10-09
申请号：US09396000
申请日：1999-03-13
申请人： Krystyna Plochocka , Jui-Chang Chuang , Jenn S. Shih
发明人： Krystyna Plochocka , Jui-Chang Chuang , Jenn S. Shih
IPC分类号： C08F232
CPC分类号： A61K8/06 , A61K8/062 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61K2800/57 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/10 , C08F226/04 , C08F216/125
摘要： A process of making a cosmetically or pharmaceutically-acceptable emulsion or gel composition which comprises: (a) heating a reaction mixture comprising, by weight, about 5-70% of a vinyl monomer in about 30-95% of an oil as solvent, wherein said oil is selected from the group consisting of a silicone oil, a mineral oil and a water-insoluble organic ester and a free radical initiator, optionally in the presence of a crosslinking agent and/or an oil soluble surfactant, with agitation, under an inert gas, at about 40-150° C., wherein the oil is present in an amount sufficient to keep the resultant vinyl polymer in a stirrable state until the end of the polymerization, (b) adding a surfactant, if a suitable surfactant was not present during polymerization, and, (c) then adding water to form an oil-in-water, a water-in-oil or a water-in-oil-in-water emulsion or gel, in a volume ratio of oil-in-water of 30:70 to 10:90, or water-in-oil of 90:10 to 30:70.
摘要翻译：制备化妆品或药学上可接受的乳液或凝胶组合物的方法，其包括：（a）加热反应混合物，该反应混合物包含以约30-95％油为溶剂的约5-70％的乙烯基单体，其中所述油选自硅油，矿物油和水不溶性有机酯和自由基引发剂，任选地在交联剂和/或油溶性表面活性剂的存在下搅拌，在惰性气体，在约40-150℃下，其中油以足以保持所得乙烯基聚合物处于可搅拌状态直至聚合结束的量存在，（b）如果合适的表面活性剂在聚合期间不存在，然后（c）然后加入水以形成水包油，油包水或水包油包水乳液或凝胶，其体积比为油 - 水分为30:70至10:90，或油包水为90:10至30:70。

3. 发明授权

US06177068B1 Vinyl amide polymer delivery system for hair and skin treating compositions 有权
标题翻译：用于头发和皮肤处理组合物的乙烯基酰胺聚合物递送系统
公开(公告)号：US06177068B1
公开(公告)日：2001-01-23
申请号：US09203910
申请日：1998-12-02
申请人： Jenn S. Shih , Jui-Chang Chuang , Krystyna Plochocka
发明人： Jenn S. Shih , Jui-Chang Chuang , Krystyna Plochocka
IPC分类号： A61K706
CPC分类号： A61K8/06 , A61K8/062 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61K2800/57 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/10 , C08F226/04 , C08F216/125
摘要： A cosmetically active oil-in-water (o/w) or water-in-oil (w/o) emulsion, for topical applications comprising (a) the reaction product of a non-aqueous, heterogeneous polymerization of a liquid reaction mixture containing between about 5 and about 70%, preferably 10-40%, by weight, of N-vinylamide monomer in an oil solvent, a free radical initiator, between about 0.1 and about 2.5% by weight of a crosslinking agent and optionally a surfactant, (b) water sufficient to form said emulsion, (c) a cosmetically active hair and/or skin treating chemical or chemical composition and optionally (d) a surfactant.
摘要翻译：用于局部应用的美容活性的水包油（o / w）或油包水（w / o）乳液，其包含（a）液态反应混合物的非水非均相聚合反应产物，其含有在油溶剂，自由基引发剂中的约5-约70重量％，优选10-40重量％的N-乙烯基酰胺单体，约0.1-约2.5重量％的交联剂和任选的表面活性剂，（b）足以形成所述乳液的水，（c）处理化学或化学成分的美容活性毛发和/或皮肤，以及任选地（d）表面活性剂。

4. 发明授权

US6048522A Controlled-release, drug-delivery composition 失效
标题翻译：控制释放，药物输送组合物
公开(公告)号：US6048522A
公开(公告)日：2000-04-11
申请号：US121380
申请日：1998-07-23
申请人： Krystyna Plochocka , Jui-Chang Chuang , Jenn S. Shih , Anil Menon , Nadhamuni G. Nerella
发明人： Krystyna Plochocka , Jui-Chang Chuang , Jenn S. Shih , Anil Menon , Nadhamuni G. Nerella
IPC分类号： A61K8/06 , A61K8/81 , A61K9/00 , A61K9/113 , A61K31/74 , A61K47/14 , A61K47/32 , A61K47/44 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F2/12 , C08F2/14 , C08F2/24 , C08F2/32 , C08F26/10 , C08F226/10 , C08G77/04 , A61K31/695 , A61K31/79
CPC分类号： A61K8/062 , A61K47/14 , A61K47/32 , A61K47/44 , A61K8/06 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/10 , A61K2800/57 , Y10T428/2987
摘要： A controlled-release, drug-delivery, emulsion composition for topical application comprising (a) the reaction product of the non-aqueous, heterogeneous polymerization of a reaction mixture of about 5-70%, preferably 10-30%, by weight, of a vinyl monomer in an oil as solvent, and a free radical initiator, optionally in the presence of a crosslinking agent and/or a surfactant, wherein the oil solvent is present in an amount sufficient to keep the resultant polymer in a stirrable state throughout the polymerization, (b) water, (c) a surfactant and (d) a pharmaceutical medicament.
摘要翻译：一种用于局部施用的控释药物递送乳剂组合物，其包含（a）反应混合物的非水非均相聚合反应产物，其反应混合物的重量比为约5-70％，优选为10-30％任选在交联剂和/或表面活性剂存在下，油中的乙烯基单体和溶剂中的自由基引发剂，其中油溶剂的存在量足以使得到的聚合物在整个过程中保持在可搅拌状态聚合，（b）水，（c）表面活性剂和（d）药物。

5. 发明授权

US5147941A Denture adhesive 失效
标题翻译：假牙胶
公开(公告)号：US5147941A
公开(公告)日：1992-09-15
申请号：US786638
申请日：1991-11-01
申请人： Mohammed Tazi , Robert B. Login , Krystyna Plochocka , Rama K. Haldar , Balgopal Gangadharan , William E. Prosise
发明人： Mohammed Tazi , Robert B. Login , Krystyna Plochocka , Rama K. Haldar , Balgopal Gangadharan , William E. Prosise
IPC分类号： A61K6/00 , C08F220/06
CPC分类号： A61K6/0026 , C08F220/06
摘要： According to this invention, there is provided a denture adhesive which is a mixed partial salt of a copolymer of maleic anhydride and acrylic acid (or methacrylic acid), optionally including a C.sub.1 -C.sub.4 alkyl vinyl ether, having a weight average molecular weight of about 30,000 to 400,000, preferably about 50,000 to 350,000. The copolymer comprises about 10 to 70 mole percent, preferably 20 to 60 mole percent, of maleic anhydride, about 30 to 90 mole percent, preferably 40 to 80 percent, of acrylic acid (or methacrylic acid), and 0 to 25 mole percent of a C.sub.1 -C.sub.4 alkyl vinyl ether.
摘要翻译：根据本发明，提供了一种义齿粘合剂，其是马来酸酐和丙烯酸（或甲基丙烯酸）的共聚物的混合的部分盐，其任选地包括C 1 -C 4烷基乙烯基醚，其重均分子量为约 30,000至400,000，优选约50,000至350,000。共聚物包含约10至70摩尔％，优选20至60摩尔％的马来酸酐，约30至90摩尔％，优选40至80重量％的丙烯酸（或甲基丙烯酸）和0至25摩尔％ C1-C4烷基乙烯基醚。

6. 发明申请

US20070036743A1 Antimicrobial polymers 审中-公开
标题翻译：抗微生物聚合物
公开(公告)号：US20070036743A1
公开(公告)日：2007-02-15
申请号：US11201223
申请日：2005-08-10
申请人： Krystyna Plochocka , Karen Winkowski , Jeffrey Lynn
发明人： Krystyna Plochocka , Karen Winkowski , Jeffrey Lynn
IPC分类号： A61K31/787 , C08L35/00
CPC分类号： C09D135/00 , A01N31/08 , A61K31/787 , C08F8/48 , C08F289/00 , C08F290/00 , C08F291/00 , C08F2800/10 , C08F2810/50 , C08G73/10 , A01N25/10 , A01N2300/00 , C08F8/32 , C08F8/14 , C08F210/10
摘要： An antimicrobial polymer which is stable to aqueous hydrolysis contains a phenolic antimicrobial agent covalently bounded to one or more polymerized ethylenically unsaturated monomer units preferably through an imide and/or amide group.
摘要翻译：对水解水解稳定的抗微生物聚合物含有共价结合一个或多个聚合烯属不饱和单体单元优选通过酰亚胺和/或酰胺基团的酚类抗微生物剂。

7. 发明申请

US20050075454A1 Process of making polymeric hydrogels by reactive extrusion 有权
标题翻译：通过反应性挤出制备聚合物水凝胶的方法
公开(公告)号：US20050075454A1
公开(公告)日：2005-04-07
申请号：US10801232
申请日：2004-03-16
申请人： Krystyna Plochocka , Timothy Bee
发明人： Krystyna Plochocka , Timothy Bee
IPC分类号： A61L15/58 , C08F8/00 , C08F261/04 , C08F261/06 , C08F265/02 , C08F283/00 , C08L71/02 , C08L73/02 , C08G63/48 , C08G63/91
CPC分类号： C08L73/02 , A61L15/585 , C08F8/14 , C08F261/04 , C08F261/06 , C08F265/02 , C08F283/00 , C08F2810/20 , C08L71/02 , C08L2205/05 , C08L35/00 , C08L2666/04 , C08F222/06
摘要： What is described is a reactive extrusion process of making a polymeric hydrogel of a polymeric anhydride or acid, e.g. maleic anhydride or maleic acid polymer, or copolymer thereof, crosslinked with a crosslinking agent containing at least 2 crosslinkable groups, particularly, —OH or —NH2, or both. The reaction product is a crosslinked polymeric ester or amide/imide, or both, suitably having a mole ratio of —OH, or —NH2, to —COOH, of 1:10 to 10:1, preferably 2:10 to 7:1. The hydrogel is particularly swellable in water, e.g. >100% in 1 hour in aqueous media; and forms a thin, tacky layer on a substrate, which property is useful in bioadhesive products.
摘要翻译：所描述的是制备聚合物酐或酸的聚合物水凝胶的反应挤出方法，例如。马来酸酐或马来酸聚合物或其共聚物与含有至少2个可交联基团，特别是-OH或-NH 2或两者的交联剂交联。反应产物是交联的聚合酯或酰胺/酰亚胺或两者，适当地具有1:10至10:1，优选2:10至7:1的-OH或-NH 2与-COOH的摩尔比。水凝胶在水中特别溶胀，例如在水介质中1小时内> 100％并且在基底上形成薄的粘性层，该性质在生物粘附产品中是有用的。

8. 发明授权

US06255421B1 Non-aqueous, heterogeneous polymerization process and reaction product obtained thereby 失效
标题翻译：由此获得非水，非均相聚合方法和反应产物
公开(公告)号：US06255421B1
公开(公告)日：2001-07-03
申请号：US08988121
申请日：1997-12-10
申请人： Krystyna Plochocka , Jui-Chang Chuang , Jenn S. Shih
发明人： Krystyna Plochocka , Jui-Chang Chuang , Jenn S. Shih
IPC分类号： C08F212
CPC分类号： C08F226/10 , A61K8/06 , A61K8/062 , A61K8/064 , A61K8/8141 , A61K9/0014 , A61K2800/57 , A61Q17/04 , A61Q19/00 , C08F2/06 , C08F226/04 , C08F216/125
摘要： A non-aqueous, heterogeneous polymerization process comprises heating a reaction mixture of about 5-70%, preferably 10-30%, by weight, of a vinyl monomer in an oil as solvent, and a free radical initiator, optionally in the presence of a crosslinking agent and/or a surfactant, wherein the oil solvent is present in an amount sufficient to keep the resultant polymer in a stirrable state throughout the polymerization. The polymer reaction product is capable of forming a uniform emulsion or gel upon addition of water thereto.
摘要翻译：非水非均相聚合方法包括加热约5-70％，优选10-30％（重量）的作为溶剂的油中的乙烯基单体和一种自由基引发剂的反应混合物，任选地在交联剂和/或表面活性剂，其中油溶剂的存在量足以使得所得聚合物在整个聚合过程中处于可搅拌状态。聚合物反应产物能够在加入水后形成均匀的乳液或凝胶。

9. 发明授权

US06214956B1 Solvent-free copolymers of maleic anhydride and alkyl vinyl ethers having a specific viscosity of 0.5 to 5 and method of making 有权
标题翻译：具有比例粘度为0.5-5的马来酸酐和烷基乙烯基醚的无溶剂共聚物和制备方法
公开(公告)号：US06214956B1
公开(公告)日：2001-04-10
申请号：US09268834
申请日：1999-03-16
申请人： Krystyna Plochocka
发明人： Krystyna Plochocka
IPC分类号： C08F22404
CPC分类号： A61K8/347 , A61K8/8164 , A61Q11/00 , C08F222/06 , C08K5/0008 , C08L35/08
摘要： Solvent-free, free-flowing, fine white powders of a copolymer of maleic anhydride and a C1-C4 alkyl vinyl ether having a specific viscosity of about 0.5 to about 5 (1% wt/v in methyl ethyl ketone, 25° C.) and substantially without residue, odor or taste. A solvent-free process of polymerizing the monomers in the presence of 0.01 to 1.9% acetaldehyde also is described.
摘要翻译：比例粘度为约0.5至约5（1％wt / v的甲基乙基酮，25℃）的马来酸酐和C1-C4烷基乙烯基醚的共聚物的无溶剂，自由流动的细白色粉末），基本上没有残留物，气味或味道。还描述了在0.01至1.9％乙醛存在下使单体聚合的无溶剂方法。

10. 发明授权

US6117416A Mouthwash composition including a solvent-free high molecular weight uncrosslinked terpolymer of maleic anhydride C.sub.1 -C.sub.4 alkyl vinyl ether and isobutylene 有权
标题翻译：漱口剂组合物包括马来酸酐C1-C4烷基乙烯基醚和异丁烯的无溶剂高分子量未交联三元共聚物
公开(公告)号：US6117416A
公开(公告)日：2000-09-12
申请号：US396026
申请日：1999-09-15
申请人： William E. Prosise , James F. Curry , Krystyna Plochocka
发明人： William E. Prosise , James F. Curry , Krystyna Plochocka
IPC分类号： A61K6/00 , A61K8/34 , A61K8/81 , A61Q11/00 , C08F222/06 , C08K5/00 , C08K5/13 , A61K7/16
CPC分类号： A61K8/347 , A61K8/8164 , A61Q11/00 , C08F222/06 , C08K5/0008 , C08K5/13
摘要： This invention relates to a mouthwash composition including a solvent-free, high molecular weight (>1,500,000) uncrosslinked terpolymer of maleic anhydride, a C.sub.1 -C.sub.4 alkyl vinyl ether and isobutylene.
摘要翻译：本发明涉及包含不含马来酸酐，C1-C4烷基乙烯基醚和异丁烯的无溶剂高分子量（> 1,500,000）未交联三元共聚物的漱口剂组合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式