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2. 发明申请

WO2006135696A3 METHOD FOR HANDLING ADHESIVE LAMINATE SECTIONS 审中-公开
标题翻译：用于处理粘合层压板部分的方法
公开(公告)号：WO2006135696A3
公开(公告)日：2007-06-07
申请号：PCT/US2006022340
申请日：2006-06-08
申请人： 3M INNOVATIVE PROPERTIES CO , KNUTSON GORDON P , SEVER JOHN M
发明人： KNUTSON GORDON P , SEVER JOHN M
IPC分类号： A61K9/70 , A61F13/02 , C09J7/02
CPC分类号： B32B37/025 , A61F2013/0296 , A61K9/703 , A61K9/7038 , B29C65/4825 , B29C2793/0036 , Y10T156/1064 , Y10T156/1077 , Y10T156/108 , Y10T156/1082 , Y10T156/1084 , Y10T156/1097
摘要： A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method.
摘要翻译：一种处理粘合剂层压体的方法，其中粘合剂层压体被可释放地粘附到第一纤维网上，包括多个切割或冲压部分，并且其中粘合层压板的相邻部分沿着幅材的纵向方向彼此连接一个或多个连接点。提供了与第一支撑结构相邻的第一支撑结构和第二支撑结构。第一个网络被引导到第一个支撑结构。提供第二纤维网并将其引导到第二支撑结构上，其中第二纤维网被定向成使得第二纤维网的释放表面面向第一支撑结构。来自第一纤维网的粘合剂层压体的第一部分的引导部分附接到第二纤维网的释放表面，并且第二纤维网前进，使得粘合剂层压体的第一部分从粘合剂层压体的第二部分分离，并且粘合剂层压体的第二部分的前缘以与粘合层压体的第一部分的后缘隔开的构造粘附到第二腹板。通过这种方法制备的透皮药物递送装置。

3. 发明申请

WO2021222215A1 ADHESIVE ARTICLE AND METHOD OF MAKING SAME 审中-公开
公开(公告)号：WO2021222215A1
公开(公告)日：2021-11-04
申请号：PCT/US2021/029354
申请日：2021-04-27
申请人： KINDEVA DRUG DELIVERY L.P. , CANTOR, Adam S. , CARLSON, Daniel H. , FENTON, James R. , FENTON, John R. , JERRY, Glen A. , KNUTSON, Gordon P. , O'HARE, Jonathan J. , PEKUROVSKY, Mikhail L. , PETERSON, Timothy A. , STENSVAD, Karl K.
发明人： CANTOR, Adam S. , CARLSON, Daniel H. , FENTON, James R. , FENTON, John R. , JERRY, Glen A. , KNUTSON, Gordon P. , O'HARE, Jonathan J. , PEKUROVSKY, Mikhail L. , PETERSON, Timothy A. , STENSVAD, Karl K.
IPC分类号： A61F13/00 , A61F13/02 , A61K9/70
摘要： Various embodiments of an adhesive article and a method of forming such article are disclosed. The adhesive article includes an active pharmaceutical ingredient; a substrate having a first surface and a second surface including a first area and a second area; and a first adhesive layer disposed on the first area of the second surface of the substrate. The active pharmaceutical ingredient is present in the first adhesive layer at a first concentration. The adhesive article also includes a second adhesive layer having a first portion that is in contact with the first adhesive layer and a second portion that is disposed in the second area of the substrate. The active pharmaceutical ingredient is present in the second adhesive layer at a second concentration. The second concentration is less than the first concentration.

4. 发明申请

WO2013096027A1 ADHESIVE PATCH ASSEMBLY WITH OVERLAY LINER AND SYSTEM AND METHOD FOR MAKING SAME 审中-公开
标题翻译：带有覆盖层的粘合配合组件及其制造方法
公开(公告)号：WO2013096027A1
公开(公告)日：2013-06-27
申请号：PCT/US2012/069037
申请日：2012-12-12
申请人： 3M INNOVATIVE PROPERTIES COMPANY , KNUTSON, Gordon P.
发明人： KNUTSON, Gordon P.
IPC分类号： C09J7/02 , A61F13/02 , A61F13/00 , A61K9/70
CPC分类号： A61K9/7076 , A61F13/0008 , A61F13/0259 , A61F2013/00646 , A61F2013/008 , A61K9/703 , A61K9/7084 , A61K31/167 , A61K31/196 , A61K31/34 , A61K31/4168 , A61K31/439 , A61K31/4439 , A61K31/4458 , A61K31/485 , A61K31/565 , A61K31/567 , B32B37/26 , B32B2037/268 , C09J7/403 , Y10T156/1049 , Y10T428/1476
摘要： An adhesive patch assembly and method for making same. The assembly can include an adhesive patch and a release liner. The patch can include a backing and a skin-contact adhesive. The release liner can further include a first portion and a second portion separated by a hinge. The first portion can be positioned to overlay the backing of the patch when the release liner is folded upon the hinge, and the second portion can be positioned to underlie the skin-contact adhesive of the patch. The method can include positioning the patch on the release liner, such that patch is located on one of the first portion and the second portion of the release liner; and folding the release liner about to locate the patch between the first portion and the second portion of the release liner.
摘要翻译：粘合贴片组件及其制造方法。该组件可以包括粘合贴片和剥离衬垫。贴剂可以包括背衬和皮肤接触粘合剂。释放衬垫还可以包括由铰链分开的第一部分和第二部分。当释放衬垫折叠在铰链上时，第一部分可以定位成覆盖贴片的背衬，并且第二部分可以被定位成在贴片的皮肤接触粘合剂下面。该方法可以包括将贴片定位在剥离衬垫上，使得贴片位于剥离衬垫的第一部分和第二部分之一上; 并且将释放衬垫折叠以将贴片定位在剥离衬垫的第一部分和第二部分之间。

5. 发明申请

WO2006055844A3 METHOD OF CONTACT COATING A MICRONEEDLE ARRAY 审中-公开
标题翻译：接触涂层麦克风阵列的方法
公开(公告)号：WO2006055844A3
公开(公告)日：2006-09-21
申请号：PCT/US2005041993
申请日：2005-11-18
申请人： 3M INNOVATIVE PROPERTIES CO , CHOI HYE-OK , KNUTSON GORDON P , DAVID MOSES M
发明人： CHOI HYE-OK , KNUTSON GORDON P , DAVID MOSES M
IPC分类号： B05D1/00 , A61M37/00
CPC分类号： B05D1/28 , A61B17/205 , A61K9/0021 , A61M37/0015 , A61M2037/0053
摘要： A method of coating a microneedle array by applying a coating fluid using a flexible film (200) in a brush-like manner. A method of coating a microneedle array (250) comprising: providing a microneedle array having a substrate and a plurality of microneedles (230); providing a flexible film; providing a coating solution (210) comprising a carrier fluid and a coating material; applying the coating solution onto a first major surface of the flexible film; performing a transfer step of bringing the first major surface of the flexible film into contact with the microneedles and removing the flexible film from contact with the microneedles; and allowing the carrier fluid to evaporate. Also, a method of coating a microneedle array by applying a coating solution onto a first major surface of a coating substrate to form a layer of applied coating solution having a thickness equal to or less than the height of at least one of the microneedles and performing a transfer step of bringing the first major surface of the coating substrate into contact with the microneedles and removing the coating substrate from contact with the microneedles, thereby transferring at least a portion of the coating solution to the microneedle array.
摘要翻译：一种通过使用柔性膜（200）以刷状方式施加涂布液来涂覆微针阵列的方法。一种涂覆微针阵列（250）的方法，包括：提供具有基底和多个微针（230）的微针阵列; 提供柔性膜; 提供包含载体流体和涂层材料的涂层溶液（210）; 将涂布溶液施加到柔性膜的第一主表面上; 执行将柔性膜的第一主表面与微针接触并移除柔性膜以与微针接触的转印步骤; 并允许载体液体蒸发。另外，通过将涂布溶液涂布到涂布基材的第一主表面上以形成厚度等于或小于至少一个微针的高度的施加的涂布溶液层，并进行涂布，从而涂布微针阵列的方法将涂布基板的第一主表面与微针接触并且移除涂布基板与微针接触的转印步骤，从而将至少一部分涂布溶液转印到微针阵列。

6. 发明申请

WO2006135696A2 METHOD FOR HANDLING ADHESIVE LAMINATE SECTIONS 审中-公开
标题翻译：用于处理粘合层压板部分的方法
公开(公告)号：WO2006135696A2
公开(公告)日：2006-12-21
申请号：PCT/US2006/022340
申请日：2006-06-08
申请人： 3M INNOVATIVE PROPERTIES COMPANY , KNUTSON, Gordon P. , SEVER, John M.
发明人： KNUTSON, Gordon P. , SEVER, John M.
IPC分类号： A61K9/70
CPC分类号： B32B37/025 , A61F2013/0296 , A61K9/703 , A61K9/7038 , B29C65/4825 , B29C2793/0036 , Y10T156/1064 , Y10T156/1077 , Y10T156/108 , Y10T156/1082 , Y10T156/1084 , Y10T156/1097
摘要： A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method.
摘要翻译：一种处理粘合剂层压体的方法，其中粘合剂层压体被可释放地粘附到第一纤维网上，包括多个切割或冲压部分，并且其中粘合层压板的相邻部分沿着幅材的纵向方向彼此连接一个或多个连接点。提供了与第一支撑结构相邻的第一支撑结构和第二支撑结构。第一个网络被引导到第一个支撑结构。提供第二纤维网并将其引导到第二支撑结构上，其中第二纤维网被定向成使得第二纤维网的释放表面面向第一支撑结构。来自第一纤维网的粘合剂层压体的第一部分的引导部分附接到第二纤维网的释放表面，并且第二纤维网前进，使得粘合剂层压体的第一部分从粘合剂层压体的第二部分分离，并且粘合剂层压体的第二部分的前缘以与粘合层压体的第一部分的后缘隔开的构造粘附到第二腹板。通过这种方法制备的透皮给药装置。

7. 发明申请

WO2006055844A2 METHOD OF CONTACT COATING A MICRONEEDLE ARRAY 审中-公开
标题翻译：接触涂层麦克风阵列的方法
公开(公告)号：WO2006055844A2
公开(公告)日：2006-05-26
申请号：PCT/US2005/041993
申请日：2005-11-18
申请人： 3M INNOVATIVE PROPERTIES COMPANY , CHOI, Hye-ok , KNUTSON, Gordon P., , DAVID, Moses M.,
发明人： CHOI, Hye-ok , KNUTSON, Gordon P., , DAVID, Moses M.,
IPC分类号： B05D1/00 , A61M37/00
CPC分类号： B05D1/28 , A61B17/205 , A61K9/0021 , A61M37/0015 , A61M2037/0053
摘要： A method of coating a microneedle array by applying a coating fluid using a flexible film in a brush-like manner. A method of coating a microneedle array comprising: providing a microneedle array having a substrate and a plurality of microneedles; providing a flexible film; providing a coating solution comprising a carrier fluid and a coating material; applying the coating solution onto a first major surface of the flexible film; performing a transfer step of bringing the first major surface of the flexible film into contact with the microneedles and removing the flexible film from contact with the microneedles; and allowing the carrier fluid to evaporate. Also, a method of coating a microneedle array by applying a coating solution onto a first major surface of a coating substrate to form a layer of applied coating solution having a thickness equal to or less than the height of at least one of the microneedles and performing a transfer step of bringing the first major surface of the coating substrate into contact with the microneedles and removing the coating substrate from contact with the microneedles, thereby transferring at least a portion of the coating solution to the microneedle array.
摘要翻译：通过以类似刷子的方式使用柔性膜施加涂布液来涂布微针阵列的方法。一种涂覆微针阵列的方法，包括：提供具有基底和多个微针的微针阵列; 提供柔性膜; 提供包含载体流体和涂层材料的涂层溶液; 将涂布溶液施加到柔性膜的第一主表面上; 执行将柔性膜的第一主表面与微针接触并移除柔性膜以与微针接触的转印步骤; 并允许载体液体蒸发。此外，通过将涂布溶液涂覆在涂布基材的第一主表面上以形成具有等于或小于至少一个微针的高度的涂覆涂层溶液的层并涂覆微针阵列的方法，并执行将涂布基板的第一主表面与微针接触并移除涂布基板与微针接触的转印步骤，从而将至少一部分涂布溶液转印到微针阵列上。

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