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1. 发明申请

US20090294360A1 Dialysis preparation 审中-公开
标题翻译：透析准备
公开(公告)号：US20090294360A1
公开(公告)日：2009-12-03
申请号：US11794824
申请日：2006-01-06
申请人： Hirotoshi Iwashina , Kiyonobu Kamiya
发明人： Hirotoshi Iwashina , Kiyonobu Kamiya
IPC分类号： B01D61/32 , A61K47/02
CPC分类号： A61M1/1654 , A61K9/08 , A61K47/02 , A61K47/12 , A61K47/26
摘要： The present invention provides a pharmaceutical composition for dialysis wherein the decline of ionized calcium concentration in an acetate-free bicarbonate dialysate comprising no acetic acid and/or sodium acetate is controlled. The present invention further provides a dialysis agent A that comprises electrolytes, citric acid and/or citrate as pH adjuster, and/or glucose, for preparation of bicarbonate dialysates; the agent A characterized by being adjusted by citric acid and/or citrate so as to keep the electrolyte ionized calcium concentration not less than 1 mmol/L in a prepared bicarbonate dialysate. In a specific aspect of the present invention, sodium citrate is used as citrate, and the present invention provides a dialysate obtained from above.
摘要翻译：本发明提供一种用于透析的药物组合物，其中控制不含乙酸和/或乙酸钠的不含乙酸酯的碳酸氢盐透析液中电离钙浓度的下降。本发明还提供一种透析剂A，其包含用于制备碳酸氢盐透析液的电解质，柠檬酸和/或柠檬酸盐作为pH调节剂和/或葡萄糖; 该试剂A的特征在于用柠檬酸和/或柠檬酸盐调节，以使电解质在制备的碳酸氢盐透析液中电离钙离子浓度不小于1mmol / L。在本发明的具体方面，柠檬酸钠用作柠檬酸盐，本发明提供由上述获得的透析液。

2. 发明申请

US20070037886A1 Bone marrow erythroid progenitor cell(s) differentiation inducer 审中-公开
标题翻译：骨髓红细胞祖细胞分化诱导物
公开(公告)号：US20070037886A1
公开(公告)日：2007-02-15
申请号：US11411024
申请日：2006-04-26
申请人： Sen Takeshita , Yuzuru Eto , Yoshiyuki Takahara , Kiyonobu Kamiya , Kazumi Tashiro , Maki Sugiyama , Hiroshi Yamamoto
发明人： Sen Takeshita , Yuzuru Eto , Yoshiyuki Takahara , Kiyonobu Kamiya , Kazumi Tashiro , Maki Sugiyama , Hiroshi Yamamoto
IPC分类号： A61K31/198
CPC分类号： A61K31/198 , A61K38/1816 , A61K2300/00
摘要： Bone marrow erythroid progenitor cell(s) differentiation may be induced and anemia may be treated by administering arginine. Arginine is an excellent differentiation inducer, because it has high safety, can be orally administered, and is widely used.
摘要翻译：可能诱导骨髓红细胞祖细胞分化，并可通过施用精氨酸治疗贫血。精氨酸是一种优良的分化诱导因子，因为它具有高度的安全性，可以口服给药，被广泛使用。

3. 发明申请

US20060257935A1 Hematopoietic factor production promoter 审中-公开
标题翻译：造血因子生产促进剂
公开(公告)号：US20060257935A1
公开(公告)日：2006-11-16
申请号：US11410948
申请日：2006-04-26
申请人： Sen Takeshita , Yuzuru Eto , Yoshiyuki Takahara , Kiyonobu Kamiya , Kazumi Tashiro , Maki Sugiyama , Hiroshi Yamamoto
发明人： Sen Takeshita , Yuzuru Eto , Yoshiyuki Takahara , Kiyonobu Kamiya , Kazumi Tashiro , Maki Sugiyama , Hiroshi Yamamoto
IPC分类号： G01N33/53
CPC分类号： G01N33/5023 , G01N33/5073 , G01N2333/505 , G01N2333/65
摘要： The present invention provides methods of screening for enhancers and/or inhibitors of a hematopoietic factor production promoter comprising arginine as an active ingredient. Arginine is an excellent hematopoietic factor production promoter, because it has high safety, can be orally administered, and is widely used.
摘要翻译：本发明提供了筛选包含精氨酸作为活性成分的造血因子产生促进剂的增强子和/或抑制剂的方法。精氨酸是一种优良的造血因子生产促进剂，因为它具有高度的安全性，可以口服给药，并被广泛应用。

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