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1. 发明专利

JP2013172975A Method and apparatus using infrared photothermal radiometry (ptr) and modulated laser luminescence (lum) for diagnostics of defects in teeth 有权
标题翻译：使用红外光电辐射测量（PTR）和调制激光发光（LUM）的方法和装置用于牙科诊断中的缺陷
公开(公告)号：JP2013172975A
公开(公告)日：2013-09-05
申请号：JP2013076844
申请日：2013-04-02
申请人： Andreas Mandelis , マンデリス,アンドレアス , Stephen Abrams , エイブラムズ,ステファン , Jin-Seok Jeon , ジョン,ジン−セオク , Kiran Kulkarni , クルカルニ,キラン , Anna Matvienko , マトヴィエンコ,アンナ
发明人： MANDELIS ANDREAS , ABRAMS STEPHEN , JEON JIN-SEOK , KULKARNI KIRAN , MATVIENKO ANNA
IPC分类号： A61B1/24 , A61B1/00 , A61B1/06 , G02B23/24 , G02B23/26
CPC分类号： A61B5/417 , A61B5/0088 , A61B5/0452 , A61B5/7228
摘要： PROBLEM TO BE SOLVED: To provide a high-spatial-resolution dynamic diagnostic instrument that can simultaneously measure laser-induced frequency-domain infrared photothermal radiometric and alternating current (ac) modulated luminescence signals from defects, demineralization, remineralization and caries in teeth intraorally.SOLUTION: An emphasis is on the abilities of a high-spatial-resolution dynamic diagnostic instrument to approach important problems such as the detection, diagnosis and ongoing monitoring of carious lesions and/or defects on the occlusal pits and fissures, smooth surfaces and interproximal areas between teeth which normally go undetected by x-ray radiographs or visual examination. The high-spatial-resolution dynamic diagnostic instrument is also able to detect early areas of demineralized tooth and/or areas of remineralized tooth as well as defects along the margins of restorations. This capability of inspecting a local spot can be extended to a modulated imaging of sub-surface of target tooth by using a multi-array infrared camera. Two configurations of the high-spatial-resolution dynamic diagnostic instrument are presented.
摘要翻译：要解决的问题：提供一种高空间分辨率动态诊断仪器，可以同时测量激光诱导的频域红外光热辐射和交流（ac）调制发光信号，从缺陷，软化，再矿化和牙齿中的龋齿。解决方案：重点是高空间分辨率动态诊断仪器处理重要问题的能力，如检测，诊断和持续监测咬合凹陷和裂缝，光滑表面和邻近区域的龋损和/或缺陷在通常未通过X射线照片或目视检查中检测到的牙齿之间。高空间分辨率动态诊断仪器还能够检测软化牙齿和/或再矿化区域的早期区域以及沿修复边缘的缺陷。通过使用多阵列红外摄像机，可以将局部斑点检测能力扩展到目标牙齿的子表面的调制成像。介绍了高空间分辨率动态诊断仪的两种配置。

2. 发明专利

IL188747D0 METHOD AND APPARATUS USING INFRARED PHOTOTHERMAL RADIOMETRY (PTR) AND MODULATED LASER LUMINESCENCE (LUM) FOR DIAGNOSTICS OF DEFECTS IN TEETH 未知
公开(公告)号：IL188747D0
公开(公告)日：2008-08-07
申请号：IL18874708
申请日：2008-01-13
申请人： ANDREAS MANDELIS , KIRAN KULKARNI , STEPHEN ABRAMS , ANNA MATIVENKO , JIN SEOK JEON
IPC分类号： A61B20100101
摘要： The present application relates to an apparatus for imaging dental tissue using modulated photothermal radiometry and luminescence for inspection of dental tissues (120) of a patient, comprising at least one modulated laser light source (90, 92) for irradiating a portion of a surface of a dental tissue with a beam of light of an effective wavelength wherein modulated photothermal radiometric signals and modulated luminescence signals are responsively emitted from said portion of the dental surface. Further, the apparatus comprises an imaging detection means positioned with respect to said dental tissue for detecting images of said emitted modulated photothermal signals and said modulated luminescence signals, said imaging detection means (170) including a combined near infrared camera for detecting images of emitted modulated luminescence signals and a mid infrared camera for detecting images of said emitted modulated photothermal signals. In addition, the apparatus has demodulating means (106) for demodulating said images of emitted modulated photothermal signals into images of photothermal phase and amplitude components and said images of modulated luminescence signals into images of luminescence phase and amplitude signals. Moreover, the apparatus comprises processing means for comparing said images of photothermal phase and amplitude signals to images of photothermal phase and amplitude signals of a reference sample and comparing said images of luminescence phase and amplitude signals to images of luminescence phase and amplitude signals of a reference sample to obtain differences, if any, between said portion of said dental tissue and said reference sample and correlating said differences with defects in said dental tissue. The apparatus has also an image display for displaying said images.

3. 发明专利

IL188747A Method and apparatus using infrared photothermal radiometry (ptr) and modulated laser luminescence (lum) for diagnostics of defects in teeth 未知
公开(公告)号：IL188747A
公开(公告)日：2014-03-31
申请号：IL18874708
申请日：2008-01-13
申请人： ANDREAS MANDELIS , KIRAN KULKARNI , STEPHEN ABRAMS , ANNA MATIVENKO , JIN SEOK JEON
摘要： The present application relates to an apparatus for imaging dental tissue using modulated photothermal radiometry and luminescence for inspection of dental tissues (120) of a patient, comprising at least one modulated laser light source (90, 92) for irradiating a portion of a surface of a dental tissue with a beam of light of an effective wavelength wherein modulated photothermal radiometric signals and modulated luminescence signals are responsively emitted from said portion of the dental surface. Further, the apparatus comprises an imaging detection means positioned with respect to said dental tissue for detecting images of said emitted modulated photothermal signals and said modulated luminescence signals, said imaging detection means (170) including a combined near infrared camera for detecting images of emitted modulated luminescence signals and a mid infrared camera for detecting images of said emitted modulated photothermal signals. In addition, the apparatus has demodulating means (106) for demodulating said images of emitted modulated photothermal signals into images of photothermal phase and amplitude components and said images of modulated luminescence signals into images of luminescence phase and amplitude signals. Moreover, the apparatus comprises processing means for comparing said images of photothermal phase and amplitude signals to images of photothermal phase and amplitude signals of a reference sample and comparing said images of luminescence phase and amplitude signals to images of luminescence phase and amplitude signals of a reference sample to obtain differences, if any, between said portion of said dental tissue and said reference sample and correlating said differences with defects in said dental tissue. The apparatus has also an image display for displaying said images.

4. 发明专利

NZ565509A Method and apparatus using infrared photothermal radiometry (PTR) and modulated laser luminescence (LUM) for diagnostics of defects in teeth 未知
公开(公告)号：NZ565509A
公开(公告)日：2011-08-26
申请号：NZ56550906
申请日：2006-07-18
申请人： ANDREAS MANDELIS , STEPHEN ABRAMS , JIN SEOK JEON , ANNA MATVIENKO , KIRAN KULKARNI
发明人： MANDELIS ANDREAS , ABRAMS STEPHEN , JEON JIN-SEOK , KULKARNI KIRAN , MATVIENKO ANNA
IPC分类号： A61B6/14 , H01L31/0256 , H01L31/101
摘要： Disclosed is an apparatus, comprising: at least one laser light source adapted to irradiate a portion of a surface of a dental tissue with a modulated laser beam of effective wavelength of at least about 659 nm such that modulated photothermal radiometric signals and modulated luminescence signals are responsively emitted from said portion of a dental surface; a first detection means for detecting said emitted modulated luminescence signals, and a second detection means for detecting said emitted modulated photothermal radiometric signals; a hand held probe head, and a flexible optical fiber bundle having a distal end connected to said hand held probe head, said optical fiber bundle including one optical fiber having a proximal end in optical communication with said light source and a distal end terminated at said hand held probe head, said optical fiber bundle including a plurality of multi-mode optical fibers having distal ends terminated at said hand held probe head, a first pre-selected number of said multi-mode optical fibers being near-infrared transmitting optical fibers and having proximal ends optically coupled to said first detection means for transmitting said modulated luminescence signals to said first detection means, and a second pre-selected number of said multi-mode optical fibers being mid-infrared-transmitting optical fibers and having proximal ends optically coupled to said second detection means; software based lock-in amplifier programmed for demodulating said emitted modulated photothermal signals into photothermal phase and amplitude signals and said modulated luminescence signals into luminescence phase and amplitude signals; and processing means programmed for comparing said photothermal phase and amplitude signals to photothermal phase and amplitude signals of a reference sample and comparing said luminescence phase and amplitude signals to luminescence phase and amplitude signals of a reference sample to obtain differences, if any, between said portion of said dental tissue and said reference sample and correlating said differences with defects in said dental tissue. Also disclosed is a method for detection of defects in dental tissue including erosive lesions, pit and fissure lesions, interproximal lesions, smooth surface lesions and root carious lesions in dental tissue, comprising the steps of: a) illuminating a portion of a surface of said dental tissue with said apparatus b) detecting emitted modulated luminescence signals from said apparatus c) demodulating signals from said apparatus into photothermal phase and amplitude components and demodulating modulated luminescence signals from said apparatus into luminescence phase and amplitude signals; and d) comparing said photothermal phase and amplitude signals to photothermal phase and amplitude signals of a reference sample and comparing said luminescence phase and amplitude signals to luminescence phase and amplitude signals of a reference sample to obtain differences, if any, between said portion of said dental tissue and said reference sample and correlating said differences with defects in said dental tissue.

5. 发明专利

ZA200801139B Method and apparatus using infrared photothermal radiometry (PTR) and modulates laser luminescence (LUM) for diagnostics of defects in teeth 未知
公开(公告)号：ZA200801139B
公开(公告)日：2008-12-31
申请号：ZA200801139
申请日：2008-02-04
申请人： ANDREAS MANDELIS , STEPHEN ABRAMS , JIN-SEOK JEON , KIRAN KULKARNI , ANNA MATVIENKO
发明人： ANDREAS MANDELIS , STEPHEN ABRAMS , JIN-SEOK JEON , KIRAN KULKARNI , ANNA MATVIENKO
IPC分类号： A61B20090101 , H01L20090101
摘要： The present application relates to an apparatus for imaging dental tissue using modulated photothermal radiometry and luminescence for inspection of dental tissues (120) of a patient, comprising at least one modulated laser light source (90, 92) for irradiating a portion of a surface of a dental tissue with a beam of light of an effective wavelength wherein modulated photothermal radiometric signals and modulated luminescence signals are responsively emitted from said portion of the dental surface. Further, the apparatus comprises an imaging detection means positioned with respect to said dental tissue for detecting images of said emitted modulated photothermal signals and said modulated luminescence signals, said imaging detection means (170) including a combined near infrared camera for detecting images of emitted modulated luminescence signals and a mid infrared camera for detecting images of said emitted modulated photothermal signals. In addition, the apparatus has demodulating means (106) for demodulating said images of emitted modulated photothermal signals into images of photothermal phase and amplitude components and said images of modulated luminescence signals into images of luminescence phase and amplitude signals. Moreover, the apparatus comprises processing means for comparing said images of photothermal phase and amplitude signals to images of photothermal phase and amplitude signals of a reference sample and comparing said images of luminescence phase and amplitude signals to images of luminescence phase and amplitude signals of a reference sample to obtain differences, if any, between said portion of said dental tissue and said reference sample and correlating said differences with defects in said dental tissue. The apparatus has also an image display for displaying said images.

6. 发明申请

US20050021645A1 Universal presence indicator and instant messaging system 审中-公开
标题翻译：通用存在指示器和即时通讯系统
公开(公告)号：US20050021645A1
公开(公告)日：2005-01-27
申请号：US10857708
申请日：2004-05-27
申请人： Kiran Kulkarni , Mahesh Murthy , Vinod Panicker
发明人： Kiran Kulkarni , Mahesh Murthy , Vinod Panicker
IPC分类号： G06F15/16 , G06Q10/10 , H04L20060101
CPC分类号： G06Q10/107
摘要： A universal presence indication and messaging system enables integrating the presence of a user into all platforms enables the user of this technology on a wired or wireless network to configure, manage and broadcast his presence to a defined or undefined set of other users on a wired or wireless network. The recipients of a presence file or image can then interact with the user through text, voice or other medium without the need for any additional software aside from standard web browser or e-mail software. The system is also independent of the operating environment of the user and the receiver of the presence indication, and independent of the need for any proprietary messaging system. This Universal Presence Indication is also fully manageable by the user.
摘要翻译：通用存在指示和消息系统使得能够将用户的存在集成到所有平台中，使得有线或无线网络上的该技术的用户能够在有线或无线网络上配置，管理和广播他的存在到定义的或未定义的其他用户集合无线网络。然后，存在文件或图像的收件人可以通过文本，语音或其他介质与用户进行交互，而不需要除标准Web浏览器或电子邮件软件之外的任何其他软件。该系统还独立于用户和接收者的存在指示的操作环境，并且独立于对任何专有消息系统的需要。该通用存在指示也是用户完全可管理的。

7. 发明申请

US20080065732A1 Referral instant messaging 审中-公开
标题翻译：推荐即时通讯
公开(公告)号：US20080065732A1
公开(公告)日：2008-03-13
申请号：US11801285
申请日：2007-05-09
申请人： Kiran Kulkarni , Vinay V
发明人： Kiran Kulkarni , Vinay V
IPC分类号： G06F15/16
CPC分类号： G06Q10/107 , G06Q30/02
摘要： A referral instant messenger link is provided on the webpage of the host website. By clicking the link, a user interface opens up that requests for authentication. Multiple instant messenger accounts of a plurality of instant messenger vendors are displayed within the user interface. The reader can choose a contact and send the universal resource locator address of the website that is currently viewed by a single click provided within the user interface. This facility eliminates the need of the reader leaving the host website in order to pursue instant messaging to send the link to his contacts. This also enables the webmaster of the host website to insert advertising material as appropriate. The web page reader does not have to download and install any new software on his or her computer for accessing the referral instant messenger (RIM).
摘要翻译：在主机网站的网页上提供推荐即时通讯链接。通过单击链接，用户界面打开请求进行身份验证。在用户界面内显示多个即时通讯商的多个即时通讯账户。读者可以选择联系人并发送当前通过用户界面中提供的单击点击查看的网站的通用资源定位器地址。该设施消除了读者离开主机网站的需要，以追求即时消息传送链接到他的联系人。这也使得主机网站的站长能够适当地插入广告材料。网页阅读器不必在他或她的计算机上下载并安装任何新软件来访问推荐即时通讯（RIM）。

8. 发明申请

US20080040436A1 Instant messaging integrated in a browser 审中-公开
标题翻译：即时通讯集成在浏览器中
公开(公告)号：US20080040436A1
公开(公告)日：2008-02-14
申请号：US11801286
申请日：2007-05-09
申请人： Bharani Vasudev Setlur , Kiran Kulkarni , Vinay Vishwanathan
发明人： Bharani Vasudev Setlur , Kiran Kulkarni , Vinay Vishwanathan
IPC分类号： G06F15/16
CPC分类号： G06Q10/107
摘要： Disclosed herein is a method and system of providing an instant messenger on a toolbar over an internet web browser. The system allows the user to access a list of instant messenger contacts in a buddy list bar upon successful authentication. The system displays multiple instant messenger accounts of a plurality of instant messenger vendors. The system provides a facility within the user interface to choose a contact, and initiate instant messaging by inputting text messages in a text box provided within the browser toolbar itself, thereby eliminating the need for a user to shift through applications, or tabs, or windows. The system also allows for the viewing the conversation between selected contacts using a conversation box integrated within the toolbar.
摘要翻译：本文公开了一种通过互联网网络浏览器在工具栏上提供即时通讯器的方法和系统。该系统允许用户在成功认证时访问好友列表栏中的即时消息联系人列表。该系统显示多个即时消息者供应商的多个即时通讯账户。该系统在用户界面内提供一个选择联系人的设施，并通过在浏览器工具栏本身提供的文本框中输入文本消息来启动即时消息，从而消除了用户通过应用程序或标签或窗口转移的需要。该系统还允许使用集成在工具栏内的会话框来查看所选联系人之间的会话。

9. 发明授权

US08306608B2 Method and apparatus using infrared photothermal radiometry (PTR) and modulated laser luminescence (LUM) for diagnostics of defects in teeth 有权
标题翻译：使用红外光热辐射测量（PTR）和调制激光发光（LUM）进行牙齿缺陷诊断的方法和设备
公开(公告)号：US08306608B2
公开(公告)日：2012-11-06
申请号：US11488194
申请日：2006-07-18
申请人： Andreas Mandelis , Stephen Abrams , Jin-Seok Jeon , Kiran Kulkarni , Anna Matvienko
发明人： Andreas Mandelis , Stephen Abrams , Jin-Seok Jeon , Kiran Kulkarni , Anna Matvienko
IPC分类号： A61B6/00 , G01N21/00 , A61C1/00
CPC分类号： A61B5/417 , A61B5/0088 , A61B5/0452 , A61B5/7228
摘要： There is provided a high-spatial-resolution dynamic diagnostic instrument which can provide simultaneous measurements of laser-induced frequency-domain infrared photothermal radiometric and alternating-current (ac) modulated luminescence signals from defects, demineralization, remineralization and caries in teeth intraorally. The emphasis is on the abilities of this instrument to approach important problems such as the detection, diagnosis and ongoing monitoring of carious lesions and or defects on the occlusal pits and fissures, smooth surfaces and interproximal areas between teeth which normally go undetected by x-ray radiographs or visual examination. The instrument is also able to detect early areas of demineralized tooth and or areas of remineralized tooth as well as defects along the margins of restorations. This capability of inspecting a local spot can be extended to a modulated imaging of sub-surface of target tooth by using a multi-array infrared camera. Two configurations of the instrument are presented.
摘要翻译：提供了一种高空间分辨率动态诊断仪器，可以同时测量激光诱导的频域红外光热辐射和交流（ac）调制的发光信号，从缺陷，软化，再矿化和齿内牙龋。重点在于该仪器能够处理重要问题，例如龋齿病变的检测，诊断和持续监测，以及咬合凹陷和裂缝，牙齿之间的平滑表面和间隙之间的缺陷，这些区域通常未被x射线检测放射照片或视觉检查。该仪器还能够检测到软化牙齿的早期区域或再矿化区域，以及沿修复边缘的缺陷。通过使用多阵列红外摄像机，可以将局部斑点检测能力扩展到目标牙齿的子表面的调制成像。介绍了仪器的两种配置。

10. 发明申请

US20070021670A1 Method and apparatus using infrared photothermal radiometry (PTR) and modulated laser luminescence (LUM) for diagnostics of defects in teeth 有权
标题翻译：使用红外光热辐射测量（PTR）和调制激光发光（LUM）进行牙齿缺陷诊断的方法和设备
公开(公告)号：US20070021670A1
公开(公告)日：2007-01-25
申请号：US11488194
申请日：2006-07-18
申请人： Andreas Mandelis , Stephen Abrams , Jin-Seok Jeon , Kiran Kulkarni , Anna Mativenko
发明人： Andreas Mandelis , Stephen Abrams , Jin-Seok Jeon , Kiran Kulkarni , Anna Mativenko
IPC分类号： A61B6/00
CPC分类号： A61B5/417 , A61B5/0088 , A61B5/0452 , A61B5/7228
摘要： There is provided a high-spatial-resolution dynamic diagnostic instrument which can provide simultaneous measurements of laser-induced frequency-domain infrared photothermal radiometric and alternating-current (ac) modulated luminescence signals from defects, demineralization, remineralization and caries in teeth intraorally. The emphasis is on the abilities of this instrument to approach important problems such as the detection, diagnosis and ongoing monitoring of carious lesions and or defects on the occlusal pits and fissures, smooth surfaces and interproximal areas between teeth which normally go undetected by x-ray radiographs or visual examination. The instrument is also able to detect early areas of demineralized tooth and or areas of remineralized tooth as well as defects along the margins of restorations. This capability of inspecting a local spot can be extended to a modulated imaging of sub-surface of target tooth by using a multi-array infrared camera. Two configurations of the instrument are presented.
摘要翻译：提供了一种高空间分辨率动态诊断仪器，可以同时测量激光诱导的频域红外光热辐射和交流（ac）调制的发光信号，从缺陷，软化，再矿化和齿内牙龋。重点在于该仪器能够处理重要问题，例如龋齿病变的检测，诊断和持续监测，以及咬合凹陷和裂缝，牙齿之间的平滑表面和间隙之间的缺陷，这些区域通常未被x射线检测放射照片或视觉检查。该仪器还能够检测到软化牙齿的早期区域或再矿化区域，以及沿修复边缘的缺陷。通过使用多阵列红外摄像机，可以将局部斑点检测能力扩展到目标牙齿的子表面的调制成像。介绍了仪器的两种配置。

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