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1. 发明申请

US20110237927A1 DEDICATED BREAST RADIATION IMAGING/THERAPY SYSTEM 有权
标题翻译：专用乳腺放射成像/治疗系统
公开(公告)号：US20110237927A1
公开(公告)日：2011-09-29
申请号：US13109460
申请日：2011-05-17
申请人： Kenneth BROOKS , Jay A. Stein , Andrew P. Smith
发明人： Kenneth BROOKS , Jay A. Stein , Andrew P. Smith
IPC分类号： A61B6/00
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/0414 , A61B6/4258 , A61B6/502 , A61N5/10 , A61N5/1081 , A61N5/1082 , A61N2005/1058 , A61N2005/1061 , A61N2005/1087 , A61N2005/1097
摘要： System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.
摘要翻译：专门用于乳房和相关组织放射治疗的系统，设备和方法以及倾向患者的成像，但如果需要或需要，也可用于仰卧患者。诸如LINAC单元之类的特殊处理辐射源产生与乳房组织特别匹配的类型和能量范围的辐射。可以使用几种成像技术中的一种或多种来定位待照射的组织并产生用于治疗计划，调整和验证的信息。

2. 发明授权

US07957508B2 Dedicated breast radiation imaging/therapy system 有权
标题翻译：专用乳房放射成像/治疗系统
公开(公告)号：US07957508B2
公开(公告)日：2011-06-07
申请号：US11944196
申请日：2007-11-21
申请人： Kenneth Brooks , Jay A. Stein , Andrew P. Smith
发明人： Kenneth Brooks , Jay A. Stein , Andrew P. Smith
IPC分类号： A61N5/10 , A61B6/04
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/0414 , A61B6/4258 , A61B6/502 , A61N5/10 , A61N5/1081 , A61N5/1082 , A61N2005/1058 , A61N2005/1061 , A61N2005/1087 , A61N2005/1097
摘要： System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.
摘要翻译：专门用于乳房和相关组织放射治疗的系统，设备和方法以及倾向患者的成像，但如果需要或需要，也可用于仰卧患者。诸如LINAC单元之类的特殊处理辐射源产生与乳房组织特别匹配的类型和能量范围的辐射。可以使用几种成像技术中的一种或多种来定位待照射的组织并产生用于治疗计划，调整和验证的信息。

3. 发明申请

US20090080602A1 Dedicated breast radiation imaging/therapy system 审中-公开
标题翻译：专用乳房放射成像/治疗系统
公开(公告)号：US20090080602A1
公开(公告)日：2009-03-26
申请号：US11903859
申请日：2007-09-24
申请人： Kenneth Brooks , Jay A. Stein , Andrew P. Smith
发明人： Kenneth Brooks , Jay A. Stein , Andrew P. Smith
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/0414 , A61B6/4258 , A61B6/502 , A61N5/10 , A61N5/1081 , A61N5/1082 , A61N2005/1058 , A61N2005/1061 , A61N2005/1087 , A61N2005/1097
摘要： System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.
摘要翻译：专门用于乳房和相关组织放射治疗的系统，设备和方法以及倾向患者的成像，但如果需要或需要，也可用于仰卧患者。诸如LINAC单元之类的特殊处理辐射源产生与乳房组织特别匹配的类型和能量范围的辐射。可以使用几种成像技术中的一种或多种来定位待照射的组织并产生用于治疗计划，调整和验证的信息。

4. 发明申请

US20080307984A1 DEBRIS COMPACTION DEVICE AND METHOD 审中-公开
标题翻译： DEBRIS压缩装置和方法
公开(公告)号：US20080307984A1
公开(公告)日：2008-12-18
申请号：US11762335
申请日：2007-06-13
申请人： Kenneth Brooks
发明人： Kenneth Brooks
IPC分类号： B30B9/00
CPC分类号： B30B9/3053 , B30B15/0017 , B65F1/1405 , B65F2240/138
摘要： A debris compaction device for use with compressing leaves within a leaf disposal bag is disclosed. One or more handles are provided on the top side of the debris compaction device to facilitate the compaction process. Air vents facilitate the channeling of air during the compaction process.
摘要翻译：公开了一种用于在叶片处理袋内压缩叶片的碎片压实装置。一个或多个手柄设置在碎片压实装置的顶侧，以便于压实过程。空气通风口有助于在压实过程中引导空气。

5. 发明授权

US06475482B1 Genetically modified tumor-targeted bacteria with reduce virulence 失效
标题翻译：具有降低毒力的转基因肿瘤靶向细菌
公开(公告)号：US06475482B1
公开(公告)日：2002-11-05
申请号：US09337689
申请日：1999-06-22
申请人： David Bermudes , Kenneth Brooks Low
发明人： David Bermudes , Kenneth Brooks Low
IPC分类号： A61K39112
CPC分类号： C07K14/255 , A61K35/74 , A61K38/00 , A61K39/00 , A61K39/0275 , A61K48/00 , A61K2039/523 , Y02A50/482 , Y02A50/484 , Y10S435/879
摘要： The invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.
摘要翻译：本发明涉及突变沙门氏菌具有遗传修饰的msbB基因，其中突变沙门氏菌能够靶向实体瘤。本发明还涉及突变沙门氏菌在实体瘤体内的生长抑制和/或还原的治疗用途。

6. 发明授权

US06447784B1 Genetically modified tumor-targeted bacteria with reduced virulence 有权
标题翻译：具有降低毒力的转基因肿瘤靶向细菌
公开(公告)号：US06447784B1
公开(公告)日：2002-09-10
申请号：US09149832
申请日：1998-09-08
申请人： David Bermudes , Kenneth Brooks Low
发明人： David Bermudes , Kenneth Brooks Low
IPC分类号： A61K39112
CPC分类号： C07K14/255 , A61K35/74 , A61K38/00 , A61K39/00 , A61K39/0275 , A61K48/00 , A61K2039/523 , Y02A50/482 , Y02A50/484 , Y10S435/879
摘要： The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also directed to Salmonella sp. containing a genetically modified msbB gene as well as an genetic modification in a biosynthetic pathway gene such as the purI gene. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.
摘要翻译：本发明涉及突变体沙门氏菌具有遗传修饰的msbB基因，其中突变沙门氏菌能够靶向实体瘤。本发明还涉及沙门氏菌属含有遗传修饰的msbB基因以及生物合成途径基因如purI基因中的遗传修饰。本发明还涉及突变沙门氏菌在实体瘤体内的生长抑制和/或减少的治疗用途。

7. 发明授权

US6080849A Genetically modified tumor-targeted bacteria with reduced virulence 失效
公开(公告)号：US6080849A
公开(公告)日：2000-06-27
申请号：US926636
申请日：1997-09-10
申请人： David Bermudes , Kenneth Brooks Low
发明人： David Bermudes , Kenneth Brooks Low
IPC分类号： A61K35/74 , A61K38/00 , A61K39/00 , A61K39/02 , A61K39/112 , A61K48/00 , C07K14/255 , C12N1/21 , C07H21/04 , C07H21/02 , A01N43/04
CPC分类号： C07K14/255 , A61K35/74 , A61K39/0275 , A61K2039/523 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/879
摘要： The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.

8. 发明授权

US4649972A Furniture round tenon crimper 失效
标题翻译：家具圆榫卷边机
公开(公告)号：US4649972A
公开(公告)日：1987-03-17
申请号：US796059
申请日：1985-11-07
申请人： Kenneth Brooks
发明人： Kenneth Brooks
IPC分类号： B27M3/28 , B27M1/02
CPC分类号： B27M3/28
摘要： Method and apparatus for crimping a round tenon for furniture manufacture, utilizing a crimping roll cluster consisting of a knurled drive roll and two idler compressing rolls. The apparatus includes means for feeding a wooden workpiece into and out of axial alignment with the crimping roll cluster; means for pressing the wooden workpiece into engagement with the knurled portion of the drive roll; means for rotating the workpiece from one to two revolutions, thus forming flutes into the tenon; and means for discharging the workpiece from the apparatus.Also disclosed is a method and apparatus for fluting a workpiece having tenons on both ends.
摘要翻译：用于压制圆形榫头用于家具制造的方法和装置，利用由滚花驱动辊和两个惰轮压缩辊组成的卷曲辊组。该装置包括用于将木制工件进给到压接辊簇的轴向对准的装置; 用于将木制工件压紧到驱动辊的滚花部分上的装置; 用于将工件从一转至两转的装置，从而将槽纹形成榫头; 以及用于从工具排出工件的装置。还公开了一种在两端上具有榫头的工件的凹槽的方法和装置。

9. 发明授权

US08964936B2 Dedicated breast radiation imaging/therapy system 有权
公开(公告)号：US08964936B2
公开(公告)日：2015-02-24
申请号：US13558146
申请日：2012-07-25
申请人： Kenneth Brooks , Jay A. Stein , Andrew P. Smith
发明人： Kenneth Brooks , Jay A. Stein , Andrew P. Smith
IPC分类号： A61B6/03 , A61B6/04 , A61N5/10 , A61B6/00
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/0414 , A61B6/4258 , A61B6/502 , A61N5/10 , A61N5/1081 , A61N5/1082 , A61N2005/1058 , A61N2005/1061 , A61N2005/1087 , A61N2005/1097
摘要： System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.

10. 发明申请

US20120288057A1 DEDICATED BREAST RADIATION IMAGING/THERAPY SYSTEM 有权
标题翻译：专用乳腺放射成像/治疗系统
公开(公告)号：US20120288057A1
公开(公告)日：2012-11-15
申请号：US13558146
申请日：2012-07-25
申请人： Kenneth BROOKS , Jay A. Stein , Andrew P. Smith
发明人： Kenneth BROOKS , Jay A. Stein , Andrew P. Smith
IPC分类号： A61B6/04
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/0414 , A61B6/4258 , A61B6/502 , A61N5/10 , A61N5/1081 , A61N5/1082 , A61N2005/1058 , A61N2005/1061 , A61N2005/1087 , A61N2005/1097
摘要： System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.
摘要翻译：专门用于乳房和相关组织放射治疗的系统，设备和方法以及倾向患者的成像，但如果需要或需要，也可用于仰卧患者。诸如LINAC单元之类的特殊处理辐射源产生与乳房组织特别匹配的类型和能量范围的辐射。可以使用几种成像技术中的一种或多种来定位待照射的组织并产生用于治疗计划，调整和验证的信息。

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