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1. 发明申请

US20130296790A1 MICRONEEDLE 有权
公开(公告)号：US20130296790A1
公开(公告)日：2013-11-07
申请号：US13881322
申请日：2011-10-24
申请人： Koichi Masaoka , Keizo Ikari , Takashi Oda , Katsunori Kobayashi , Hidetoshi Hamamoto , Masaki Ishibashi , Kiyotsuna Toyohara
发明人： Koichi Masaoka , Keizo Ikari , Takashi Oda , Katsunori Kobayashi , Hidetoshi Hamamoto , Masaki Ishibashi , Kiyotsuna Toyohara
IPC分类号： A61M37/00
CPC分类号： A61M37/0015 , A61M2037/0023 , A61M2037/0053 , A61M2037/0061
摘要： Provided are a microneedle and a microneedle array which have both aspects of safety and easiness to use and can administer a predetermined dose of a medical agent without causing a pain by smoothly running into the skin surface layer of a patient, the microneedle comprising a frustum and a forward end portion thereon, having a forward end apex angle in the range of 15 to 60° and a forward end diameter in the range of 1 to 20 μm and satisfying the following expression (1), H/D≧5 (1) (H: Height of the whole, D: Diameter of bottom surface of the frustum).
摘要翻译：提供了一种微针和微针阵列，其具有安全性和易于使用的两个方面，并且可以通过平滑地进入患者的皮肤表面层而施加预定剂量的药剂而不引起疼痛，所述微针包括截头锥体和其前端部具有15-60°的前端顶角和1〜20μm的前端直径，满足下式（1）：H / D> = 5（1 ）（H：整体高度，D：截头锥体底面的直径）。

2. 发明授权

US07473723B2 Spectacles lens and production method thereof 失效
标题翻译：眼镜镜片及其制作方法
公开(公告)号：US07473723B2
公开(公告)日：2009-01-06
申请号：US10586641
申请日：2005-01-19
申请人： Keizo Ikari , Jiro Ariki
发明人： Keizo Ikari , Jiro Ariki
IPC分类号： C08K5/3417 , C08K5/1535
CPC分类号： G02B1/041 , C08K5/1535 , C08K5/3435 , C08L69/00
摘要： A spectacles lens and an optical transparent molded article are provided that are formed from a polycarbonate resin composition comprising: (1) 100 parts by weight of polycarbonate resin (A), (2) 0.05 to 0.5 parts by weight of at least one ultraviolet absorber (B) selected from the group consisting of 2-(2′-hydroxy-5′-methylphenyl)benzotriazole (B-1) and 2-(2′-hydroxy-5′-tert-octylphenyl)benzotriazole (B-2), (3) 0.01 to 0.3 parts by weight of at least one ultraviolet absorber (C) selected from the group consisting of 2-(3-tert-butyl-5-methyl-2-hydroxyphenyl)-5-chlorobenzotriazole (C-1), 2,2′-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazole) -2-ylphenol] (C-2) and 2-[2-hydroxy-3,5-bis(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole (C-3), and (4) 0.0005 to 0.1 parts by weight of lactone compound having a specific structure.
摘要翻译：提供由聚碳酸酯树脂组合物形成的眼镜片和光学透明模制品，其包含：（1）100重量份的聚碳酸酯树脂（A），（2）0.05至0.5重量份的至少一种紫外线吸收剂（B-2），2-（2'-羟基-5'-甲基苯基）苯并三唑（B-1）和2-（2'-羟基-5'-叔辛基苯基）苯并三唑（B-2），（3）0.01〜0.3重量份的选自2-（3-叔丁基-5-甲基-2-羟基苯基）-5-氯苯并三唑（C-1）的至少一种紫外线吸收剂（C）），2,2'-亚甲基双[4-（1,1,3,3-四甲基丁基）-6-（2H-苯并三唑）-2-基苯酚]（C-2）和2- [2-羟基-3，（α，α-二甲基苄基）苯基] -2H-苯并三唑（C-3）和（4）0.0005〜0.1重量份具有特定结构的内酯化合物。

3. 发明授权

US09636490B2 Microneedle 有权
公开(公告)号：US09636490B2
公开(公告)日：2017-05-02
申请号：US13881322
申请日：2011-10-24
申请人： Koichi Masaoka , Keizo Ikari , Takashi Oda , Katsunori Kobayashi , Hidetoshi Hamamoto , Masaki Ishibashi , Kiyotsuna Toyohara
发明人： Koichi Masaoka , Keizo Ikari , Takashi Oda , Katsunori Kobayashi , Hidetoshi Hamamoto , Masaki Ishibashi , Kiyotsuna Toyohara
IPC分类号： A61M5/00 , A61M37/00
CPC分类号： A61M37/0015 , A61M2037/0023 , A61M2037/0053 , A61M2037/0061
摘要： A microneedle and a microneedle array, which have both aspects of safety and easiness to use and can administer a predetermined dose of a medical agent without causing a pain by smoothly running into the skin surface layer of a patient, includes a frustum and a forward end portion thereon, the forward end portion having a forward end apex angle in the range of 15 to 60° and a forward end diameter in the range of 1 to 20 μm and satisfying the expression H/D≧5, where H is a total height of the microneedle, and D is a diameter of a bottom surface of the frustum).

4. 发明申请

US20070228587A1 Spectacle lens 审中-公开
标题翻译：眼镜镜片
公开(公告)号：US20070228587A1
公开(公告)日：2007-10-04
申请号：US11597404
申请日：2005-05-24
申请人： Keizo Ikari
发明人： Keizo Ikari
IPC分类号： B29D11/00
CPC分类号： C08K5/3475 , C08K5/103 , C08K5/49 , G02B1/041 , C08L69/00
摘要： There is provided a spectacle lens formed from a polycarbonate resin composition comprising, based on (1) 100 parts by weight of polycarbonate resin (component a), (2) 0.1 to 0.5 parts by weight of at least one ultraviolet absorber (component b) selected from the group consisting of 2,2′-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2 H-benzotriazole-2-yl)phenol] and 2-[2-hydroxy-3,5-bis(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole, (3) 0.005 to 2 parts by weight of mold releasing agent (component c) which substantially comprises a full ester of an aliphatic tetrahydric to octahydric alcohol having 5 to 30 carbon atoms and an aliphatic carboxylic acid having 10 to 22 carbon atoms and which has an acid value of 4 to 20, and (4) 0.001 to 0.2 parts by weight of phosphorus-based stabilizer (component d). According to the present invention, there is provided a spectacle lens formed from a polycarbonate resin composition which has molding heat resistance in molding of the spectacle lens by injection molding or extrusion compression molding, especially, molding heat resistance which allows the composition to endure long-term high-temperature retention, shows a little change in hue even if a heat history is added and has good mold releasability. Further, according to the present invention, there is provided a spectacle lens which substantially does not allow ultraviolet radiation of 385 nm to penetrate therethrough and has high total light transmittance and excellent transparency.
摘要翻译：提供一种由聚碳酸酯树脂组合物形成的眼镜片，其包含：（1）100重量份的聚碳酸酯树脂（a成分），（2）0.1至0.5重量份的至少一种紫外线吸收剂（组分b）选自2,2'-亚甲基双[4-（1,1,3,3-四甲基丁基）-6-（2H-苯并三唑-2-基）苯酚]和2- [2-羟基-3 ，5-双（α，α-二甲基苄基）苯基] -2H-苯并三唑，（3）0.005〜2重量份脱模剂（组分c），其基本上包含具有5个脂肪族四元醇与八元醇的全酯至30个碳原子和具有10至22个碳原子并且酸值为4至20的脂族羧酸，和（4）0.001至0.2重量份的磷基稳定剂（组分d）。根据本发明，提供一种由聚碳酸酯树脂组合物形成的眼镜片，该聚碳酸酯树脂组合物通过注射成型或挤出压缩成型而具有成型耐热性，特别是成型耐热性，其允许组合物耐久长寿，即使添加了热历史并且具有良好的脱模性，色调也会稍微改变。此外，根据本发明，提供了一种基本上不允许385nm的紫外线照射穿透其并具有高总透光率和优异透明度的眼镜镜片。

5. 发明申请

US20070155867A1 Spectacles lens and production method thereof 失效
标题翻译：眼镜镜片及其制作方法
公开(公告)号：US20070155867A1
公开(公告)日：2007-07-05
申请号：US10586641
申请日：2005-01-19
申请人： Keizo Ikari , Jiro Ariki
发明人： Keizo Ikari , Jiro Ariki
IPC分类号： C08K5/00 , C08K5/15
CPC分类号： G02B1/041 , C08K5/1535 , C08K5/3435 , C08L69/00
摘要： A spectacles lens and an optical transparent molded article are provided that are formed from a polycarbonate resin composition comprising: (1) 100 parts by weight of polycarbonate resin (A), (2) 0.05 to 0.5 parts by weight of at least one ultraviolet absorber (B) selected from the group consisting of 2-(2′-hydroxy-5′-methylphenyl)benzotriazole (B-1) and 2-(2′-hydroxy-5′-tert-octylphenyl)benzotriazole (B-2), (3) 0.01 to 0.3 parts by weight of at least one ultraviolet absorber (C) selected from the group consisting of 2-(3-tert-butyl-5-methyl-2-hydroxyphenyl)-5-chlorobenzotriazole (C-1), 2,2′-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazole)-2-ylphenol] (C-2) and 2-[2-hydroxy-3,5-bis(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole (C-3), and (4) 0.0005 to 0.1 parts by weight of lactone compound having a specific structure.
摘要翻译：提供由聚碳酸酯树脂组合物形成的眼镜片和光学透明模制品，其包含：（1）100重量份的聚碳酸酯树脂（A），（2）0.05至0.5重量份的至少一种紫外线吸收剂（B-2），2-（2'-羟基-5'-甲基苯基）苯并三唑（B-1）和2-（2'-羟基-5'-叔辛基苯基）苯并三唑（B-2），（3）0.01〜0.3重量份的选自2-（3-叔丁基-5-甲基-2-羟基苯基）-5-氯苯并三唑（C-1）的至少一种紫外线吸收剂（C）），2,2'-亚甲基双[4-（1,1,3,3-四甲基丁基）-6-（2H-苯并三唑）-2-基苯酚]（C-2）和2- [2-羟基-3，（α，α-二甲基苄基）苯基] -2H-苯并三唑（C-3）和（4）0.0005〜0.1重量份具有特定结构的内酯化合物。

6. 发明授权

US4929316A Method of manufacturing organic semi-conductor solid electrolytic capacitor 失效
标题翻译：有机半导体固体电解电容器的制造方法
公开(公告)号：US4929316A
公开(公告)日：1990-05-29
申请号：US400906
申请日：1989-08-30
申请人： Yoshihiro Harakawa , Seiya Takahashi , Koji Izawa , Hidemitsu Takeuchi , Keizo Ikari
发明人： Yoshihiro Harakawa , Seiya Takahashi , Koji Izawa , Hidemitsu Takeuchi , Keizo Ikari
IPC分类号： H01G9/028 , C25D9/02 , H01G9/02 , H01G9/025
CPC分类号： H01G9/025 , C25D9/02
摘要： A method of manufacturing an organic semi-conductor solid electrolytic capacitor wherein a conductive polymer thin film layer of a heterocyclic compound, i.e., pyrrole, thiophene or furan, is formed as a solid electrolyte on the surface of a metal substrate having a dielectric oxide film formed thereon by electrolytic oxidation polymerization carried out in an electrolytic solution which contains pyrrole, thiophene or furan as a heterocyclic compound and an aliphatic or aromatic sulfonic acid or a salt thereof as a supporting electrolyte in an organic solvent, for example, acetonitrile, acetone or propylene carbonate.
摘要翻译：一种制造有机半导体固体电解电容器的方法，其中在具有电介质氧化物膜的金属基板的表面上形成杂环化合物的导电聚合物薄膜层，即吡咯，噻吩或呋喃作为固体电解质通过在含有作为杂环化合物的吡咯，噻吩或呋喃的电解液中进行的电解氧化聚合，在有机溶剂例如乙腈，丙酮或丙酮中作为支持电解质的脂肪族或芳香族磺酸或其盐碳酸丙烯酯。

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