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1. 发明授权

US10513685B2 Method for differentiating pluripotent mammalian stem cells into a population of hepatic cells in a microchamber 有权
公开(公告)号：US10513685B2
公开(公告)日：2019-12-24
申请号：US13636855
申请日：2011-03-23
申请人： Yoko Itchoda , Go Tazaki , Masaya Hosoda , Motohiro Fukuda , Hideki Taniguchi , Yun-Wen Zheng , Keisuke Sekine
发明人： Yoko Itchoda , Go Tazaki , Masaya Hosoda , Motohiro Fukuda , Hideki Taniguchi , Yun-Wen Zheng , Keisuke Sekine
IPC分类号： C12N5/071 , C12N5/0735 , C12M1/32
摘要： Provided is a method that achieves control of embryoid body size and can induce differentiation in a state where the embryoid body size is controlled, by using a cell culture chamber having a plurality of microchambers formed therein. A culture method for causing differentiation of pluripotent mammalian cells uses a cell culture chamber (10) having a plurality of microchambers (11) formed on a culture surface. The cell culture chamber (10) has a culture surface formed of spaces in which the microchambers (11) have a space structure with a height of 10 μm to 500 μm and a bottom area of 100 μm2 to 1 mm2. The culture method for causing differentiation of pluripotent mammalian cells includes culturing pluripotent mammalian cells to obtain a cell population at least partially differentiated into endoderm lineage cells, by using the cell culture chambers (10).

2. 发明申请

US20160297212A1 IMAGE FORMING APPARATUS 有权
标题翻译：图像形成装置
公开(公告)号：US20160297212A1
公开(公告)日：2016-10-13
申请号：US15096423
申请日：2016-04-12
申请人： Soichi SAIGA , Keisuke SEKINE , Tomonori NAITO , Shinichiro NARUSE
发明人： Soichi SAIGA , Keisuke SEKINE , Tomonori NAITO , Shinichiro NARUSE
IPC分类号： B41J11/66 , B26D1/04 , B26D5/00
CPC分类号： B41J11/663 , B26D1/045 , B26D5/005 , B41J11/706
摘要： An image forming apparatus includes a sheet feeder, a carriage, a cutter, a cutter unit, and a controller. A first standby position and a second standby position are disposed on both ends of a range of movement of the carriage. The carriage does not contact the cutter unit at each of the first standby position and the second standby position. The controller is configured to control the carriage and the cutter unit to overlappingly move. In an image recording condition in which images are consecutively recorded in a plurality of pages on a sheet, the controller is configured to change a direction of movement of the carriage at a leading end of a page so that the direction of movement of the carriage is the same as a direction of movement of the cutter unit at a sheet cutting position at which the cutter cuts the sheet.
摘要翻译：图像形成装置包括片材进给器，托架，切割器，切割器单元和控制器。第一待机位置和第二待机位置设置在滑架的运动范围的两端。滑架在第一待机位置和第二待机位置中的每一个处不接触切割器单元。控制器被配置为控制托架和切割器单元重叠移动。在将图像连续记录在纸张上的多页中的图像记录条件下，控制器被配置为改变在页面的前端处的滑架的移动方向，使得滑架的移动方向为与切割器单元在切割刀片切割片材的切割位置处的移动方向相同。

3. 发明申请

US20130071932A1 CULTURE METHOD FOR CAUSING DIFFERENTIATION OF PLURIPOTENT MAMMALIAN CELLS 审中-公开
标题翻译：培养方法，用于引起巨噬细胞的分化
公开(公告)号：US20130071932A1
公开(公告)日：2013-03-21
申请号：US13636855
申请日：2011-03-23
申请人： Yoko Itchoda , Go Tazaki , Masaya Hosoda , Motohiro Fukuda , Hideki Taniguchi , Yun-Wen Zheng , Keisuke Sekine
发明人： Yoko Itchoda , Go Tazaki , Masaya Hosoda , Motohiro Fukuda , Hideki Taniguchi , Yun-Wen Zheng , Keisuke Sekine
IPC分类号： C12N5/071 , C12N5/095 , C12N5/076 , C12N5/0735
CPC分类号： C12N5/0606 , C12M23/12 , C12N2502/28 , C12N2506/02 , C12N2535/10
摘要： Provided is a method that achieves control of embryoid body size and can induce differentiation in a state where the embryoid body size is controlled, by using a cell culture chamber having a plurality of microchambers formed therein. A culture method for causing differentiation of pluripotent mammalian cells uses a cell culture chamber (10) having a plurality of microchambers (11) formed on a culture surface. The cell culture chamber (10) has a culture surface formed of spaces in which the microchambers (11) have a space structure with a height of 10 μm to 500 μm and a bottom area of 100 μm2 to 1 mm2. The culture method for causing differentiation of pluripotent mammalian cells includes culturing pluripotent mammalian cells to obtain a cell population at least partially differentiated into endoderm lineage cells, by using the cell culture chambers (10).
摘要翻译：提供了通过使用其中形成有多个微室的细胞培养室，实现胚状体大小的控制并且可以在控制胚状体大小的状态下诱导分化的方法。用于引起多能哺乳动物细胞分化的培养方法使用在培养表面上形成有多个微室（11）的细胞培养室（10）。细胞培养室（10）具有由空间形成的培养面，其中微室（11）具有高度为10μm〜500μm，底面积为100μm2〜1mm2的空间结构。引起多能哺乳动物细胞分化的培养方法包括通过使用细胞培养室（10）培养多能哺乳动物细胞以获得至少部分分化为内胚层谱系细胞的细胞群。

4. 发明授权

US09789709B2 Image forming apparatus 有权
公开(公告)号：US09789709B2
公开(公告)日：2017-10-17
申请号：US15096423
申请日：2016-04-12
申请人： Soichi Saiga , Keisuke Sekine , Tomonori Naito , Shinichiro Naruse
发明人： Soichi Saiga , Keisuke Sekine , Tomonori Naito , Shinichiro Naruse
IPC分类号： B41J11/70 , B41J11/66 , B26D5/00 , B26D1/04
CPC分类号： B41J11/663 , B26D1/045 , B26D5/005 , B41J11/706
摘要： An image forming apparatus includes a sheet feeder, a carriage, a cutter, a cutter unit, and a controller. A first standby position and a second standby position are disposed on both ends of a range of movement of the carriage. The carriage does not contact the cutter unit at each of the first standby position and the second standby position. The controller is configured to control the carriage and the cutter unit to overlappingly move. In an image recording condition in which images are consecutively recorded in a plurality of pages on a sheet, the controller is configured to change a direction of movement of the carriage at a leading end of a page so that the direction of movement of the carriage is the same as a direction of movement of the cutter unit at a sheet cutting position at which the cutter cuts the sheet.

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