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    • 7. 发明授权
    • Method for producing bis [.beta.(N,N-dimethylamino)ethyl]ether
    • 双[(N,N-二甲基氨基)乙基]醚的制备方法
    • US4625064A
    • 1986-11-25
    • US597312
    • 1984-04-06
    • Sadakatsu KumoiKeiji MitaraiYukihiro Tsutsumi
    • Sadakatsu KumoiKeiji MitaraiYukihiro Tsutsumi
    • C07C217/08C07C67/00C07C213/00C07C93/04
    • C07C209/12C07C213/00C07C217/00C07C217/08
    • An improved process for preparing a bis [.beta.-(N,N-dimethylamino)ethyl]ether by reacting a bismethohalide of bis [.beta.-(N,N-dimethylamino)ethyl]ether represented by the following general formula: ##STR1## (wherein X denotes a halogen atom), with an aliphatic amine having a boiling point of not lower than 220.degree. C. at atmospheric pressure and having a primary amino group in the molecule thereof. The process comprises the following two steps (a) and (b): (a) a step of distilling out water at a temperature of not more than 130.degree. C. under reduced pressure from a mixture of said bismethohalide aqueous solution and said aliphatic amine to provide a concentration of said bismethohalide to water of not less than 85% by weight, and (b) a step of reacting said bismethohalide and amine in a solid-liquid phase at a temperature of not lower than 140.degree. C.
    • 通过使由以下通式表示的双[β-(N,N-二甲基氨基)乙基]醚的双氯代双酚反应制备双[β-(N,N-二甲基氨基)乙基]醚的改进方法: 其中X表示卤素原子),其中在大气压下沸点不低于220℃并在其分子中具有伯氨基的脂族胺。 该方法包括以下两个步骤(a)和(b):(a)在减压下从所述二氯二苯醚水溶液和所述脂族胺的混合物中蒸出不超过130℃的温度的步骤 以提供不低于85重量%的所述二氯酮对水的浓度,和(b)在固液相中在不低于140℃的温度下使所述双氯苯胺和胺反应的步骤。