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    • 7. 发明申请
    • Intraocular Lens Injector with Hydrophilic Coating
    • 具有亲水性涂层的眼内透镜注射器
    • US20100256651A1
    • 2010-10-07
    • US12754122
    • 2010-04-05
    • Dharmendra JaniKaustubh S. Chitre
    • Dharmendra JaniKaustubh S. Chitre
    • A61F9/007G02B1/12
    • B29C59/16A61F2/1664B05D3/063B05D5/04B05D5/08B29C59/165B29C2035/0827B29K2995/0092
    • An IOL injector that includes one or more polymeric portions that include a hydrophilic coating component that is effective to facilitate the passage of the IOL through the injector, particularly an injector tip. The IOL injector is prepared by a process that includes irradiating at least a portion of a polymeric, IOL injector with UV light in an environment comprising oxygen to provide a positive percent change in the atomic oxygen content of the polymer material at the surface as determined by X-ray Photoelectron Spectroscopy (XPS). A portion or the entire irradiated portion is then contacted with a solution comprising a hydrophilic coating component. The hydrophilic coating component is selected from a hydrophilic polymer, a hydrophilic copolymer or any one mixture thereof to provide a solution coated portion. The solution coated portion is then heated at a temperature to provide portions of the IOL injector with a shelf-stable, lubricious hydrophilic coating to facilitate delivery of an IOL from the injector.
    • IOL注射器,其包括一个或多个聚合物部分,其包括亲水涂层组分,其有效地促进IOL通过注射器,特别是注射器尖端。 IOL注射器通过一种方法制备,该方法包括在包含氧的环境中用UV光照射聚合物IOL注射器的至少一部分,以提供在表面处的聚合物材料的原子氧含量的正百分比变化,如由 X射线光电子能谱(XPS)。 然后将一部分或全部照射部分与包含亲水涂层组分的溶液接触。 亲水性涂料组分选自亲水性聚合物,亲水性共聚物或其任何混合物,以提供溶液涂布部分。 然后将溶液涂覆的部分在一定温度下加热,以使部分IOL注射器具有稳定的,润滑的亲水性涂层,以便于从注射器输送IOL。