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1. 发明授权

US4874581A O.sub.2 /CO.sub.2 control in blood oxygenators 失效
标题翻译：氧气/二氧化碳在血液中的控制
公开(公告)号：US4874581A
公开(公告)日：1989-10-17
申请号：US216070
申请日：1988-07-07
申请人： Karl M. Sutherland , Matthew Jenusaitia
发明人： Karl M. Sutherland , Matthew Jenusaitia
IPC分类号： A61M1/32
CPC分类号： A61M1/32 , Y10S128/03
摘要： A blood oxygenator which independently controls the rate of oxygen and carbon dioxide exchange between an oxygen enriched gas and the blood. The oxygenator of the invention includes a gas inlet mechanism for diverting oxygen enriched gas between two different pathways. The first flow pathway feeds the oxygen bearing gas to a diffusion plate or sparger for the purpose of forming bubbles which diffuse into the blood to facilitate the exchange of oxygen and carbon dioxide between the gas and blood. The second flow pathway feeds oxygen down into the interior of the oxygenator as a substantially continuous stream which creates a substantially single gas bubble, or is simple a substantially continuous flow of gas with the oxygenator. This continuous flow of gas affects a gas exchange across the blood-gas interface, with carbon dioxide diffusing into the gas at substantially the same diffusion rate as occurs with the microbubbles diffusing into the blood, but with a lower diffusion rate for the oxygen.
摘要翻译：一种血液氧合器，其独立地控制富氧气体和血液之间的氧气和二氧化碳交换速率。本发明的氧合器包括用于在两个不同通路之间转移富氧气体的气体入口机构。第一流动通道将含氧气体供给到扩散板或分布器，目的是形成扩散到血液中的气泡，以促进气体和血液之间的氧气和二氧化碳的交换。第二流动路径将氧气作为基本上连续的流将氧气输送到充氧器的内部，其产生基本上单一的气泡，或者简单地与氧合器基本上连续地流动气体。这种连续的气流影响了血液 - 气体界面上的气体交换，其中二氧化碳以与扩散入血液的微泡发生的扩散速率基本相同，但以较低的氧气扩散速率扩散到气体中。

2. 发明授权

US4490254A Blood filter 失效
标题翻译：血液过滤器
公开(公告)号：US4490254A
公开(公告)日：1984-12-25
申请号：US124312
申请日：1980-02-25
申请人： Lucas S. Gordon , Karl M. Sutherland
发明人： Lucas S. Gordon , Karl M. Sutherland
IPC分类号： A61M1/36 , B01D27/00 , B01D29/21 , B01D36/00 , B01D35/00 , B01D19/02
CPC分类号： B01D36/001 , A61M1/3627 , B01D27/00 , B01D29/21
摘要： This invention relates to a blood filter assembly in which blood enters at the bottom end of the assembly, is directed in spirally upward path and then passes through a filter medium. After passing through the filter medium, the blood flows downwardly out of an outlet in the bottom end of the assembly. A gas vent is provided at the top end of the assembly. In its preferred embodiment, the outer shell of the assembly tapers from the bottom end to a narrower diameter top end, the filter medium is generally shaped in the form of a cylindrical tube and a core member is provided radially inwardly of said filter medium and spaced therefrom. This filter assembly is particularly useful for the removal of particulate matter, gas and other foreign materials from blood.
摘要翻译：血液过滤器组件本发明涉及一种血液过滤器组件，其中血液进入组件的底端，被引导成螺旋上升的路径，然后通过过滤介质。在通过过滤介质之后，血液向下流出组件底端的出口。在组件的顶端设有排气口。在其优选实施例中，组件的外壳从底端到较窄直径的顶端逐渐变细，过滤介质通常成形为圆柱形管的形式，并且芯构件设置在所述过滤介质的径向向内并且间隔开由此。该过滤器组件特别可用于从血液中除去颗粒物质，气体和其它异物。

3. 发明授权

US5061236A Venous reservoir with improved inlet configuration and integral screen for bubble removal 失效
标题翻译：具有改进的入口配置的静脉储存器和用于除气的整体屏幕
公开(公告)号：US5061236A
公开(公告)日：1991-10-29
申请号：US554759
申请日：1990-07-16
申请人： Karl M. Sutherland , William R. Patterson
发明人： Karl M. Sutherland , William R. Patterson
IPC分类号： A61J1/10 , A61M1/14 , A61M1/34 , A61M1/36 , A61M39/02
CPC分类号： A61M1/3627 , A61M2039/0202 , A61M2206/11
摘要： A blood reservoir device comprising a generally flexible blood collection chamber having an inlet portion and a main portion. The inlet portion is preferably sized and configured such that blood entering the inlet portion will avoid turbulence and will undergo generally laminar flow through the inlet portion, into the main portion of the chamber. A vent tube is provided for venting coalesced or collected gas bubbles from the top edge of the chamber. Additionally, one or more filter elements may be positioned within the chamber to further facilitate removal of air bubbles from blood passing through the chamber.
摘要翻译：一种血液储存装置，包括具有入口部分和主要部分的大体柔性的血液收集室。优选地，入口部分的尺寸和构造使得进入入口部分的血液将避免湍流并且通常通过入口部分层流流入腔室的主要部分。提供排气管用于从腔室的顶部边缘排出聚结或收集的气泡。此外，一个或多个过滤器元件可以被定位在腔室内以进一步便于从通过腔室的血液中去除气泡。

4. 发明授权

US4684508A Blood heat exchanger 失效
标题翻译：血液热交换器
公开(公告)号：US4684508A
公开(公告)日：1987-08-04
申请号：US860710
申请日：1986-05-05
申请人： Karl M. Sutherland
发明人： Karl M. Sutherland
IPC分类号： A61M5/44 , A61M1/14 , F28D3/02 , F28F1/14 , F28F1/36
CPC分类号： A61M5/44 , A61M2205/366 , Y10S128/03 , Y10S261/28
摘要： An improved structure for directing the flow of blood and blood foam onto a heat exchanger in a bubble blood oxygenator is disclosed. An extended skirt extends from the plate where venous blood and oxygen are mixed to the top of the heat exchanger of the blood oxygenator. Blood and blood foam flow downwardly uniformly over the mixing plate and evenly onto the heat exchanger. Full utilization of the heat exchanger may thereby be more easily achieved.
摘要翻译：公开了一种用于将血液和血液泡沫的流动引导到气泡血液充氧器中的热交换器上的改进的结构。延伸的裙部从静脉血和氧混合的板延伸到血液充氧器的热交换器的顶部。血液和血液泡沫在混合板上均匀地向下流动，并均匀地流到热交换器上。因此可以更容易地实现热交换器的充分利用。

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