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1. 发明授权

US08187878B2 Methods for increasing definitive endoderm differentiation of pluripotent human embryonic stem cells with PI-3 kinase inhibitors 有权
标题翻译：用PI-3激酶抑制剂增加多能人胚胎干细胞的确定性内胚层分化的方法
公开(公告)号：US08187878B2
公开(公告)日：2012-05-29
申请号：US11573662
申请日：2005-08-15
申请人： Stephen Dalton , Allan Sheppard , Karen Jones , E. Edward Baetge , Kevin A. D'Amour , Alan D. Agulnick
发明人： Stephen Dalton , Allan Sheppard , Karen Jones , E. Edward Baetge , Kevin A. D'Amour , Alan D. Agulnick
IPC分类号： C12N5/00 , C12N5/075
CPC分类号： C12N5/0606 , C12N2500/34 , C12N2501/16 , C12N2501/405
摘要： The present invention provides compositions and methods for the production of differentiated mammalian cells. More particularly, the present invention provides cellular differentiation methods employing culturing the cells on a feeder layer or under feeder-free conditions in cell culture and further contacting the cells with an inhibitor of the PI3-kinase pathway and a member of the TGFb family for the generation of differentiated mammalian cells from pluripotent mammalian stem cells. Preferably, the differentiated cell is selected from the group consisting of a mesendodermal cell, a mesodermal cell, and an endodermal cell.
摘要翻译：本发明提供用于产生分化的哺乳动物细胞的组合物和方法。更具体地，本发明提供细胞分化方法，其使用在饲养层上培养细胞或在无饲养条件下在细胞培养中培养细胞，并进一步使细胞与PI3-激酶途径的抑制剂和TGFb家族的成员接触，用于从多能哺乳动物干细胞中产生分化的哺乳动物细胞。优选地，分化细胞选自中胚层细胞，中胚层细胞和内胚层细胞。

2. 发明申请

US20100089858A1 CONVERTIBLE BABY FEEDING BOTTLE FOR USE WITH OR WITHOUT A DISPOSABLE BAG 审中-公开
标题翻译：可转换婴儿喂食用或不使用袋子
公开(公告)号：US20100089858A1
公开(公告)日：2010-04-15
申请号：US12577013
申请日：2009-10-09
申请人： Tara Karen Jones-Francis
发明人： Tara Karen Jones-Francis
IPC分类号： A61J9/00
CPC分类号： A61J9/001 , A61J9/00
摘要： A baby feeding bottle which is capable of being used either with or without a disposable bag, has a hollow cylindrical elongated body that defines an inner chamber and a circular opening at each end. A first cap is provided which includes a nipple which is capable of covering one opening at an end of the cylindrical body by being twisted onto the elongated body. A second cap is provided which is capable of being twisted onto the other end of the elongated body for forming a leak resistant covering with the other opening.
摘要翻译：能够使用或不使用一次性袋的婴儿奶瓶具有中空的圆柱形细长体，其在每个端部限定内腔和圆形开口。提供了第一盖，其包括能够通过扭转到细长体上而覆盖在圆筒体的端部处的一个开口的接头。提供第二盖，其能够扭转到细长主体的另一端以与另一个开口形成防漏盖。

3. 发明申请

US20060189253A1 Body-shaping apparel 有权
标题翻译：身体成型服装
公开(公告)号：US20060189253A1
公开(公告)日：2006-08-24
申请号：US11337750
申请日：2006-01-23
申请人： Karen Jones
发明人： Karen Jones
IPC分类号： A41C3/00
CPC分类号： A41C1/003 , A41B9/001 , A41B11/125 , A41B11/14 , A41B2400/38
摘要： The present invention provides body-shaping apparel designed to lift and support the lower portion of a person's buttocks relative to the top of the person's thighs that include a pair of loop straps that are dimensioned to encircle and engage the top of a person's thigh at the juncture of the thigh and buttock and to lift and support a buttock upwardly relative to the top of the person's thigh
摘要翻译：本发明提供了身体成形服装，其被设计用于提升和支撑人的臀部相对于人的大腿的顶部的下部，包括一对环带，其尺寸被设计成环绕并接合人的大腿的顶部大腿和臀部的关节，并相对于人的大腿的顶部向上抬起和支撑臀部

4. 发明授权

US09180825B1 Vehicle door protective cushion 有权
标题翻译：车门保护垫
公开(公告)号：US09180825B1
公开(公告)日：2015-11-10
申请号：US14121441
申请日：2014-09-05
申请人： Karen Jones
发明人： Karen Jones
IPC分类号： E05F7/00 , B60R13/04 , E06B7/28
CPC分类号： B60R13/043 , E05F5/06 , E05Y2800/40 , E05Y2900/531 , E06B7/28
摘要： A moldable protective cushion for a vehicle door, having a central portion, a first end and a second end, and a receiving groove or aperture having a first moldable wall and a second moldable wall. The receiving groove or aperture being positioned in the central portion of the protective cushion, and extends along a first arm and a second arm of the cushion. The first and second arms are joined at a corner forming a protective cushion. The protective cushion is positioned and secured to a vehicle door by molding the first moldable wall and the second moldable wall to conform to a corner of the vehicle door.
摘要翻译：一种用于车门的可模制保护垫，具有中心部分，第一端和第二端，以及具有第一可模制壁和第二可模制壁的接收槽或孔。接收槽或孔定位在保护垫的中心部分中，并沿衬垫的第一臂和第二臂延伸。第一和第二臂在形成保护垫的拐角处接合。保护垫通过模制第一可模制壁和第二可模制壁而与车门定位并固定，以符合车门的一角。

5. 发明申请

US20130212434A1 FIELD TESTER FOR TOPOLOGIES UTILIZING ARRAY CONNECTORS AND MULTI-WAVELENGTH FIELD TESTER FOR TOPOLOGIES UTILIZING ARRAY CONNECTORS 有权
标题翻译：使用阵列连接器和多波长场景测试仪的场地测试仪使用阵列连接器的拓扑学
公开(公告)号：US20130212434A1
公开(公告)日：2013-08-15
申请号：US13372374
申请日：2012-02-13
申请人： Sena E. R. Janky , Glenn Keltto , Steve O'Hara , J. David Schell , Elizabeth Bacon , Karen Jones
发明人： Sena E. R. Janky , Glenn Keltto , Steve O'Hara , J. David Schell , Elizabeth Bacon , Karen Jones
IPC分类号： G06F11/28
CPC分类号： H04L43/0817 , H04B10/071 , H04L41/22 , H04L43/50
摘要： A test instrument provides suggested next operational step function to provide a user with assistance during testing. A display is provided to show the amount of a project that has been completed, for example as a percentage completed value. Individual test results may be saved to a ‘fix later’ list, which may be later accessed to re-test items that may not have passed on initial testing.
摘要翻译：测试仪器提供建议的下一个操作步骤功能，以便在测试期间向用户提供帮助。提供显示以显示已完成的项目的数量，例如作为百分比完成值。单个测试结果可能会保存到“修复后续”列表中，稍后可能会被访问以重新测试初始测试时可能未通过的项目。

6. 植物专利

USPP11992P2 Apple tree ‘Joburn’ 失效
标题翻译：苹果树“Joburn”
公开(公告)号：USPP11992P2
公开(公告)日：2001-07-17
申请号：US08979898
申请日：1997-11-26
申请人： Graeme Jones , Karen Jones
发明人： Graeme Jones , Karen Jones
IPC分类号： A01H500
CPC分类号： A01H6/7418 , A01H5/08
摘要： A new and distinct variety of apple tree is a limb mutation of the ‘Braeburn’ variety (an unpatented New Zealand variety), with the fruit of the new variety characterized by a much more highly colored red striped and blushed appearance as compared to ‘Braeburn’. The new variety has been named ‘Joburn’.
摘要翻译：一种新的和独特的苹果树是“Braeburn”品种（一种非专利的新西兰品种）的肢体突变，新品种的果实特征是与“Braeburn”相比，颜色更加鲜艳红色条纹和脸红。 '。新品种被命名为“Joburn”。

7. 发明申请

US20070281355A1 Compositions And Methods For Self-Renewal And Differentiation In Human Embryonic Stem Cells 有权
标题翻译：人胚胎干细胞自我更新和分化的组成和方法
公开(公告)号：US20070281355A1
公开(公告)日：2007-12-06
申请号：US11573662
申请日：2005-08-15
申请人： Stephen Dalton , Allan Sheppard , Karen Jones , E. Baetge , Kevin D'Amour , Alan Agulnick
发明人： Stephen Dalton , Allan Sheppard , Karen Jones , E. Baetge , Kevin D'Amour , Alan Agulnick
IPC分类号： C12N5/08
CPC分类号： C12N5/0606 , C12N2500/34 , C12N2501/16 , C12N2501/405
摘要： The present invention provides compositions and methods for the production of differentiated mammalian cells. More particularly, the present invention provides cellular differentiation methods employing culturing the cells on a feeder layer or under feeder-free conditions in cell culture and further contacting the cells with an inhibitor of the PI3-kinase pathway for the generation of differentiated mammalian cells from pluripotent mammalian stem cells. Preferably, the differentiated cell is selected from the group consisting of a mesendodermal cell, a mesodermal cell, and an endodermal cell.
摘要翻译：本发明提供用于产生分化的哺乳动物细胞的组合物和方法。更具体地，本发明提供细胞分化方法，其使用在饲养层上培养细胞或在细胞培养物中的无饲养条件下培养细胞，并进一步使细胞与PI3-激酶途径的抑制剂接触，用于从多能性产生分化的哺乳动物细胞哺乳动物干细胞。优选地，分化细胞选自中胚层细胞，中胚层细胞和内胚层细胞。

8. 发明申请

US20050033018A1 Receptors and membrane-associated proteins 审中-公开
标题翻译：受体和膜相关蛋白
公开(公告)号：US20050033018A1
公开(公告)日：2005-02-10
申请号：US10477714
申请日：2002-05-16
申请人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
发明人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
IPC分类号： G01N33/50 , A61K45/00 , A61K49/00 , A61P1/00 , A61P3/00 , A61P25/00 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/06 , C07K14/47 , C07K14/705 , C07K16/28 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译：本发明提供鉴定和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。本发明还提供用于诊断，治疗或预防与REMAP的异常表达相关的紊乱的方法。

9. 发明授权

US09077646B2 Method and apparatus for testing and displaying test results 有权
标题翻译：测试和显示测试结果的方法和设备
公开(公告)号：US09077646B2
公开(公告)日：2015-07-07
申请号：US13372374
申请日：2012-02-13
申请人： Sena E. R. Janky , Glenn Keltto , Steve O'Hara , J David Schell , Elizabeth Bacon , Karen Jones
发明人： Sena E. R. Janky , Glenn Keltto , Steve O'Hara , J David Schell , Elizabeth Bacon , Karen Jones
IPC分类号： G06F3/048 , H04L12/24 , H04L12/26 , H04B10/071 , G06F3/01
CPC分类号： H04L43/0817 , H04B10/071 , H04L41/22 , H04L43/50
摘要： A test instrument provides suggested next operational step function to provide a user with assistance during testing. A display is provided to show the amount of a project that has been completed, for example as a percentage completed value. Individual test results may be saved to a ‘fix later’ list, which may be later accessed to re-test items that may not have passed on initial testing.
摘要翻译：测试仪器提供建议的下一个操作步骤功能，以便在测试期间向用户提供帮助。提供显示以显示已完成的项目的数量，例如作为百分比完成值。单个测试结果可能会保存到“修复后续”列表中，稍后可能会被访问以重新测试初始测试时可能未通过的项目。

10. 发明申请

US20060216706A1 Proteins associated with cell growth, differentiation, and death 审中-公开
标题翻译：与细胞生长，分化和死亡相关的蛋白质
公开(公告)号：US20060216706A1
公开(公告)日：2006-09-28
申请号：US10484603
申请日：2002-07-16
申请人： Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
发明人： Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/47 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , G01N33/574 , G01N2510/00
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译：本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。

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