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1. 发明申请

US20080273709A1 SYSTEMS AND METHODS FOR TUNING, ANALYSIS AND DISPLAY OF HEART SOUNDS 审中-公开
标题翻译：用于振动，分析和显示心音的系统和方法
公开(公告)号：US20080273709A1
公开(公告)日：2008-11-06
申请号：US12109346
申请日：2008-04-25
申请人： Arvind Thiagarajan , Damon J. Coffman , Jay Jethwa , Kamil Unver
发明人： Arvind Thiagarajan , Damon J. Coffman , Jay Jethwa , Kamil Unver
IPC分类号： A61B7/04
CPC分类号： A61B7/04 , A61B5/0006 , A61B7/005 , G16H40/63
摘要： A tunable auscultation system includes a heart sound acquirer for sensing heart sounds from at least one chest location of the patient. An initial conditioner then conditions the heart sounds through pre-amplification and anti-aliasing. The heart sounds are transduced into electrical signals by a signal processor. The electric heart signals are then tuned by an analysis tool. The analysis tool includes an interaction tuner, a processing tuner and an output tuner. The interaction tuner includes a preset tuning selector and a dynamic range tuning selector. The processing tuner includes a band pass filter and an algorithmic extraction engine which applies extraction algorithms to the electric heart signals, segments them and extracts signals of interest. Signals of interest may be correlated to specific pathologies. The output tuner includes a signal strength indicator, a diagnosis indicator, an overlapping cardiac cycle display and a display configuration engine. A display module provides output.
摘要翻译：可调谐听诊系统包括用于感测来自患者的至少一个胸部位置的心脏声音的心脏声音获取器。然后，初始调节器通过预放大和抗锯齿来调节心音。心音由信号处理器转换成电信号。然后通过分析工具调整电心脏信号。分析工具包括交互调谐器，处理调谐器和输出调谐器。交互调谐器包括预置调谐选择器和动态范围调谐选择器。处理调谐器包括带通滤波器和算法提取引擎，其将提取算法应用于电心脏信号，对它们进行分段并提取感兴趣的信号。感兴趣的信号可能与特定病理学相关。输出调谐器包括信号强度指示器，诊断指示器，重叠的心律周期显示和显示配置引擎。显示模块提供输出。

2. 发明申请

US20100256485A1 MICROWAVE CARDIOPULMONARY SENSING METHOD AND APPARATUS 审中-公开
标题翻译：微波心脏感测方法和装置
公开(公告)号：US20100256485A1
公开(公告)日：2010-10-07
申请号：US12296857
申请日：2007-04-12
申请人： Jon Gordan Ables , Suzan Pollicino , Cong Nhin Huynh , Robert Douglas Shaw , Kamil Unver
发明人： Jon Gordan Ables , Suzan Pollicino , Cong Nhin Huynh , Robert Douglas Shaw , Kamil Unver
IPC分类号： A61B6/00
CPC分类号： A61B5/05 , A61B5/0205 , A61B5/0507
摘要： A method and system of monitoring changes in a body, the method comprising the steps of: (a) emitting microwave radiation from a set of spaced apart transmitters placed adjacent the body; (b) separately receiving a radiation pattern from the transmitters via at least one receiver; (c) analysing the differences between the separately received radiation patterns to determine changes in the body.
摘要翻译：一种监测身体变化的方法和系统，所述方法包括以下步骤：（a）从邻近所述身体放置的一组间隔开的发射器发射微波辐射; （b）经由至少一个接收器分别从发射机接收辐射图; （c）分析单独接收的辐射图之间的差异，以确定身体的变化。

3. 发明申请

US20080167566A1 SYSTEMS AND METHODS FOR DETERMINING SYSTOLIC TIME INTERVALS 审中-公开
标题翻译：用于确定综合时间间隔的系统和方法
公开(公告)号：US20080167566A1
公开(公告)日：2008-07-10
申请号：US11969750
申请日：2008-01-04
申请人： Kamil Unver , Damon J. Coffman , Tat-Jin Teo , Arvind Thiagarajan
发明人： Kamil Unver , Damon J. Coffman , Tat-Jin Teo , Arvind Thiagarajan
IPC分类号： A61B5/0255
CPC分类号： A61B5/0215 , A61B5/0006 , A61B5/02028 , A61B5/0408 , A61B7/00 , A61B8/4472 , A61B8/488 , A61B2562/0204
摘要： A method and system for determining systolic time intervals, by analysis of radio frequency (RF) scatter patterns in conjunction with Electrocardiogram (ECG) data, is provided. An RF emitter is placed on the cardiac patient. The emitter includes two or more transmitting antennas which emit RF radiation into the cardiac patient, resulting in an RF scatter pattern. An RF sensor receives the scattered RF signals. The RF emitted from the antennas will differ spatially with regard to the RF sensor, causing the RF scatter patterns to differ from one another. A signal processor analyzes these differences to identify inhomogeneous structures, and to identify aortic valve motion, including aortic valve opening and closure. An electrocardiogram identifies the onset of the cardiac cycle. Systolic intervals are determined using the onset of the cardiac cycle and the aortic valve motion. Cardiac contractility also is determined by correlation to systolic intervals. An acoustic sensor is used to verify the aortic valve closure.
摘要翻译：提供了一种通过分析射频（RF）散射图与心电图（ECG）数据来确定收缩时间间隔的方法和系统。 RF发射器放置在心脏病人身上。发射器包括将RF辐射发射到心脏病人中的两个或更多个发射天线，产生RF散射图。 RF传感器接收散射的RF信号。相对于RF传感器，从天线发射的RF在空间上将不同，导致RF散射图彼此不同。信号处理器分析这些差异以识别不均匀的结构，并且识别主动脉瓣运动，包括主动脉瓣开放和闭合。心电图识别心脏周期的发作。使用心动周期和主动脉瓣运动的发作来确定收缩间期。心脏收缩也由与收缩期间隔的相关性决定。使用声学传感器来验证主动脉瓣闭合。

4. 发明申请

US20080154144A1 SYSTEMS AND METHODS FOR CARDIAC CONTRACTILITY ANALYSIS 审中-公开
标题翻译：心脏收缩分析的系统与方法
公开(公告)号：US20080154144A1
公开(公告)日：2008-06-26
申请号：US11955267
申请日：2007-12-12
申请人： Kamil Unver , Damon J. Coffman , Tat-Jin Teo , Arvind Thiagarajan
发明人： Kamil Unver , Damon J. Coffman , Tat-Jin Teo , Arvind Thiagarajan
IPC分类号： A61B5/02
CPC分类号： A61B5/0408 , A61B5/02028 , A61B7/00 , A61B7/04 , A61B8/06 , A61B8/488 , A61B2562/02 , A61B2562/0204 , A61B2562/046
摘要： A method and system of cardiac contractility analysis is provided. Cardiac contractility may include indices such as ejection fraction (EF) and rate of change in pressure (dP/dt) in a heart. Heart sounds may be measured and calibrated by attenuation. Likewise, a first acoustic peak in the first heart sound (S1), and a second acoustic peak of the second heart sound (S2) may be identified. The first heart sound (S1) may be calibrated by the second heart sound (S2). Amplitudes of calibrated heart sounds may be correlated to cardiac contractility. Electrical activity and acoustics of the heart are measured. The pre-ejection period of the cardiac cycle may be calculated. The left ventricular ejection time of the cardiac cycle may likewise be calculated. Then a ratio of pre-ejection period over left ventricular ejection time may be calculated and correlated to cardiac contractility. Pressure on the acoustic sensor may be used to calibrate acoustic data.
摘要翻译：提供心肌收缩分析的方法和系统。心脏收缩力可能包括心脏中的射血分数（EF）和压力变化率（dP / dt）等指标。可以通过衰减来测量和校准心音。类似地，可以识别第一心音（S1）中的第一声峰值和第二心音（S2）的第二声峰。第一心音（S1）可以通过第二心音（S2）进行校准。校准心音的幅度可能与心脏收缩相关。测量心脏的电活动和声学。可以计算心动周期的预喷射周期。心脏周期的左心室射血时间同样可以计算。然后，可以计算预喷射周期与左心室射血时间的比例，并与心脏收缩力相关。声学传感器上的压力可用于校准声学数据。

5. 发明申请

US20080039733A1 SYSTEMS AND METHODS FOR CALIBRATION OF HEART SOUNDS 审中-公开
标题翻译：用于校准心脏声音的系统和方法
公开(公告)号：US20080039733A1
公开(公告)日：2008-02-14
申请号：US11762930
申请日：2007-06-14
申请人： Kamil Unver , Damon J. Coffman , Tat-Jin Teo , Arvind Thiagarajan
发明人： Kamil Unver , Damon J. Coffman , Tat-Jin Teo , Arvind Thiagarajan
IPC分类号： A61B5/02
CPC分类号： A61B7/04 , A61B5/02028 , A61B5/0408 , A61B7/00 , A61B8/06 , A61B8/488 , A61B2562/02 , A61B2562/0204 , A61B2562/046
摘要： An auscultation system includes a transducer for generating an acoustic signal at a transducing location of the subject, and a sensor for receiving an attenuated acoustic signal at a sensing location of the subject. The attenuated signal received at the sensing location is digitized, and may be analyzed in the frequency and/or time domain. The comparison of the digitized attenuated signal against the initial transduced signal allows for the computation of the degree of acoustic attenuation between the transducing and sensing locations. Acoustic attenuation may be utilized to generate an intensity ratio. The ejection fraction of the heart subject may then be computed by correlation to the intensity ratio. Pulse echo methods are also disclosed. The echo transducer is oriented on the subject and generates a series of signal pulses. The return echo on the pulse is then received and a brightness encoded image is produced. The return echo provides location data on the internal structures of the subject including location, motion and speed.
摘要翻译：听诊系统包括用于在受试者的转导位置处产生声学信号的换能器，以及用于在对象的感测位置接收衰减的声学信号的传感器。在感测位置处接收的衰减信号被数字化，并且可以在频域和/或时域中进行分析。数字化衰减信号与初始转换信号的比较允许计算传感和感测位置之间的声衰减程度。可以使用声衰减来产生强度比。然后可以通过与强度比的相关性来计算心脏受试者的射血分数。还公开了脉冲回波方法。回波传感器定向在被摄体上并产生一系列信号脉冲。然后接收脉冲上的返回回波并产生亮度编码图像。返回回波提供主体内部结构的位置数据，包括位置，运动和速度。

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