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1. 发明申请

WO03074103A2 PREFILLED SYRINGE 审中-公开
标题翻译：预先注射
公开(公告)号：WO03074103A2
公开(公告)日：2003-09-12
申请号：PCT/JP0213690
申请日：2002-12-26
申请人： TERUMO CORP , KASAI MASAAKI , TACHIKAWA KOUICHI , KOYAMA SHINGO
发明人： KASAI MASAAKI , TACHIKAWA KOUICHI , KOYAMA SHINGO
IPC分类号： F16J15/10 , A61M20060101 , A61M5/28 , A61M5/31 , A61M5/315 , A61M
CPC分类号： A61M5/31596 , A61M5/2459 , A61M5/31513 , A61M2005/2462 , A61M2005/31598
摘要： A two-chamber type prefilled syringe (1A), wherein chemical (100) is stored in a first space (27) surrounded by an outer tube (2) and a first gasket (3) and liquid (200) is stored in a second space (46) surrounded by an inner tube (4) and a second gasket (5), and when an opening/closing mechanism part (7A) capable of switching the state of communication between the first space (27) and the second space (46) is opened and the inner tube (4) is moved in the base end direction thereof relative to the outer tube (2), the liquid (200) flows into the first space (27), and the second gasket (5) in the inner tube (4) slidably moves in the tip direction of the inner tube, whereby, since a large worn portion formed of the broken part (56) of a coated layer (55) is provided on the second gasket (5) moved near the tip of the inner tube (4), the second gasket (5) can be prevented from returning in the base end direction of the inner tube.
摘要翻译：二室式预充式注射器（1A），其中化学品（100）储存在由外管（2）和第一垫圈（3）和液体（200）围绕的第一空间（27）中，第二由内管（4）和第二垫片（5）包围的空间（46），以及当能够切换第一空间（27）和第二空间（27）之间的连通状态的开闭机构部（7A） 46）打开，内管（4）相对于外管（2）在其基端方向移动，液体（200）流入第一空间（27），第二垫圈（5）内管（4）在内管的顶端方向上可滑动地移动，由此，由第二垫圈（5）上的被涂层（55）的断裂部分（56）形成的大的磨损部分设置在靠近可以防止内管（4）的前端，第二垫圈（5）在内管的基端方向返回。

2. 发明申请

WO1989003375A1 ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME 审中-公开
标题翻译：异噻吩衍生物和含有其的药物制剂
公开(公告)号：WO1989003375A1
公开(公告)日：1989-04-20
申请号：PCT/JP1988001046
申请日：1988-10-14
申请人： TERUMO KABUSHIKI KAISHA , ONISHI, Hiroyuki , KOYAMA, Shingo , NANBA, Ryoichi , MIYAOKA, Syozo , MASUDA, Akira , SHIKATA, Yoshiyuki , USHIJIMA, Hideto , MUROTA, Seiitsu
发明人： TERUMO KABUSHIKI KAISHA
IPC分类号： C07C49/248
CPC分类号： C07C235/34 , C07C45/66 , C07C45/673 , C07C45/72 , C07C49/248 , C07C49/255
摘要： Isoprenoid derivatives represented by general formula (I), wherein R represents a hydrogen atom or a lower alkyl group, X represents -CH2-, -O- or -NH-, n represents 1 or 2, the number of double bonds of trans configuration, and m represents an integer of 0 to 3. The compounds have the activity of inhibiting the action of 5-lipoxygenase and are useful as drugs for treating allergy, nephritis, hepatitis, rheumatism, gastric ulcer, etc.

3. 发明申请

WO1989006648A1 CYSTEAMINE DERIVATIVES AND ANTI-RHEUMATIC AGENT CONTAINING SAME 审中-公开
标题翻译： CYSTEAMINE衍生物和含有相同抗菌药物
公开(公告)号：WO1989006648A1
公开(公告)日：1989-07-27
申请号：PCT/JP1989000044
申请日：1989-01-19
申请人： TERUMO KABUSHIKI KAISHA , SHIMIZU, Masaki , KOYAMA, Shingo , KOHAMA, Hiromasa , NANBA, Ryoichi , INOUE, Kazuhito
发明人： TERUMO KABUSHIKI KAISHA
IPC分类号： C07C149/24
CPC分类号： C07D295/192 , C07C323/41 , C07C323/42 , C07D277/04 , C07D277/18 , C07D333/20
摘要： Cysteamine derivatives represented by general formula (I) (wherein R1 represents a straight-chain or branched alkyl group containing 1 to 6 carbon atoms, R2 represents a hydrogen atom or an n-propyl group, and X represents a group containing a cysteamine moiety (N$(1,3)$S) and represented by general formulae (II), (III), (IV), (V) or (VI) wherein R2 represents a hydrogen atom or a straight-chain or branched alkyle group containing 1 to 10 carbon atoms) are disclosed. These cysteamine derivatives are effective as antirtheumatic agents.

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