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1. 发明申请

WO1998012343A1 PROCESSES FOR PRODUCING SUGAR NUCLEOTIDES AND COMPLEX CARBOHYDRATES 审中-公开
标题翻译：生产蔗糖核糖体和复合碳水化合物的方法
公开(公告)号：WO1998012343A1
公开(公告)日：1998-03-26
申请号：PCT/JP1997003226
申请日：1997-09-12
申请人： KYOWA HAKKO KOGYO CO., LTD. , KOIZUMI, Satoshi , SASAKI, Katsutoshi , ENDO, Tetsuo , TABATA, Kazuhiko , OZAKI, Akio
发明人： KYOWA HAKKO KOGYO CO., LTD.
IPC分类号： C12P19/26
CPC分类号： C12P19/30
摘要： A process for producing sugar nucleotides with the use of, as enzyme sources, a) an optionally treated culture of a microorganism capable of producing NTP from a nucleotide precursor, and b) an optionally treated culture of a microorganism capable of producing a sugar nucleotide from a sugar and NTP; a process for producing complex carbohydrates with the use of, as enzymes sources, the above-mentioned cultures a) and b), and c) an optionally treated culture of a microorganism, animal cells or insect cells capable of producing a complex carbohydrate from a sugar nucleotide and a complex carbohydrate precursor; a process for producing complex carbohydrates with the use of, as an enzyme source, an optionally treated culture of a microorganism, animal cells or insect cells capable of producing a complex carbohydrate from a sugar nucleotide and a complex carbohydrate precursor; and a process for producing N-acetylglucosamine-1-phosphate with the use of, as an enzyme source, an optionally treated culture of a microorganism having a potent galactokinase activity.
摘要翻译：一种使用作为酶源的糖核苷酸的制备方法，a）任选处理的能够从核苷酸前体产生NTP的微生物培养物，以及b）任选处理的能够产生糖核苷酸的微生物培养物，糖和NTP; 使用作为酶来源的上述培养物a）和b）来生产复合碳水化合物的方法，以及c）任选处理的能够从其生产复合碳水化合物的微生物，动物细胞或昆虫细胞培养物糖核苷酸和复合碳水化合物前体; 使用能够从糖核苷酸和复合碳水化合物前体产生复合碳水化合物的微生物，动物细胞或昆虫细胞的任选处理的培养物作为酶源生产复合碳水化合物的方法; 以及使用具有强烈半乳糖激酶活性的微生物任选处理的培养物作为酶源生产N-乙酰葡糖胺-1-磷酸的方法。

2. 发明申请

WO03027297A9 PROCESS FOR PRODUCING alpha2,3/alpha2,8-SIALYLTRANSFERASE AND SIALIC ACID-CONTAINING COMPLEX SUGAR 审中-公开
标题翻译：生产α2,3/α2,8-异亮氨酸酶和含有酸的复合糖的方法
公开(公告)号：WO03027297A9
公开(公告)日：2003-09-04
申请号：PCT/JP0209907
申请日：2002-09-26
申请人： KYOWA HAKKO KOGYO KK , ENDO TETSUO , KOIZUMI SATOSHI
发明人： ENDO TETSUO , KOIZUMI SATOSHI
IPC分类号： C12N1/21 , C12N9/10 , C12N15/54 , C12P21/02
CPC分类号： C12N9/1081
摘要： A process for producing a protein having an alpha2,3/alpha2,8-sialyltransferase activity with the use of a transformant containing a DNA encoding a protein having an alpha2,3/alpha2,8-sialyltransferase activity originating in a microorganism belonging to the genus Pasteurella, and a sialic acid-containing complex sugar with the use of a transformant producing a protein having an alpha2,3/alpha2,8-sialyltransferase activity originating in a microorganism.
摘要翻译：使用含有编码具有源自属于该属的微生物的具有α2,3/α2,8-唾液酸转移酶活性的蛋白质的DNA的转化体来生产具有α2,3/α2,8-唾液酸转移酶活性的蛋白质的方法巴斯德氏菌素和含唾液酸的复合糖，其使用产生具有源于微生物的α2,3/α2,8-唾液酸转移酶活性的蛋白质的转化体。

3. 发明申请

WO1998011247A1 PROCESSES FOR PRODUCING SUGAR NUCLEOTIDES AND COMPLEX CARBOHYDRATES 审中-公开
标题翻译：生产蔗糖核糖体和复合碳水化合物的方法
公开(公告)号：WO1998011247A1
公开(公告)日：1998-03-19
申请号：PCT/JP1997003225
申请日：1997-09-12
申请人： KYOWA HAKKO KOGYO CO., LTD. , KOIZUMI, Satoshi , KAWANO, Hisaji , KINO, Kuniki , OZAKI, Akio
发明人： KYOWA HAKKO KOGYO CO., LTD.
IPC分类号： C12P19/00
CPC分类号： C12P19/305 , C12N9/1051 , C12P19/02 , C12P19/18 , C12P19/26 , C12P19/30
摘要： A process for producing a sugar nucleotide characterized by using as an enzyme source an optionally processed culture of a microorganism capable of producing the sugar nucleotide from a nucleotide precursor and a sugar, effecting an enzymatic reaction in an aqueous medium containing the enzyme source, the nucleotide precursor and the sugar to thereby accumulate the sugar nucleotide in the medium, and taking up the sugar nucleotide from the medium; and a process for producing a complex carbohydrate characterized by using as enzyme sources an optionally processed culture of a microorganism capable of producing a sugar nucleotide from a nucleotide precursor and a sugar, and an optionally processed culture of a microorganism or animal cells capable of producing the complex carbohydrate from the sugar nucleotide and a complex carbohydrate precursor, effecting enzymatic reactions in an aqueous medium containing these enzyme sources, the nucleotide precursor, the sugar and the complex carbohydrate precursor to thereby accumulate the complex carbohydrate in the medium, and taking up the complex carbohydrate from the medium.
摘要翻译：一种制备糖核苷酸的方法，其特征在于使用能够从含有酶源的水性介质中进行酶反应的核苷酸前体和糖产生糖核苷酸的微生物任选加工的培养物作为酶源，核苷酸前体和糖，从而在培养基中积聚糖核苷酸，并从培养基中摄取糖核苷酸; 其特征在于使用能够从核苷酸前体和糖产生糖核苷酸的微生物任选加工的培养物，以及能够生产所述微生物或动物细胞的任选加工的培养物作为酶源的复合碳水化合物的生产方法来自糖核苷酸的复合碳水化合物和复合碳水化合物前体，在含有这些酶源的水性介质，核苷酸前体，糖和复合碳水化合物前体中进行酶促反应，从而在培养基中积聚复合碳水化合物，并吸收复合物碳水化合物从培养基中。

4. 发明申请

WO9940205A8 GLYCOSYLTRANSFERASE AND DNA ENCODING THE SAME 审中-公开
标题翻译： GLYCOSYLTRANSFERASE和编码DNA的DNA
公开(公告)号：WO9940205A8
公开(公告)日：1999-11-04
申请号：PCT/JP9900321
申请日：1999-01-27
申请人： KYOWA HAKKO KOGYO KK , KOIZUMI SATOSHI , ENDO TETSUO , TABATA KAZUHIKO , OZAKI AKIO
发明人： KOIZUMI SATOSHI , ENDO TETSUO , TABATA KAZUHIKO , OZAKI AKIO
IPC分类号： C12N15/09 , C12N1/21 , C12N9/10 , C12N15/00 , C12N15/54 , C12P19/18 , C12R1/01 , C12R1/19 , C12Q1/68
CPC分类号： C12N9/1051 , C12N9/1048 , C12P19/18 , Y10S435/822
摘要： A protein having a beta 1,4-galactosyltransferase activity: a DNA encoding this protein; a recombinant DNA containing this DNA; a transformant carrying this recombinant DNA; a process for producing beta 1,4-galactosyltransferase by using this transformant; and a process for producing a galactose-containing saccharide by using the above transformant.
摘要翻译：具有β1,4-半乳糖基转移酶活性的蛋白质：编码该蛋白质的DNA; 含有该DNA的重组DNA; 携带该重组DNA的转化子; 通过使用该转化体生产β-1,4-半乳糖基转移酶的方法; 以及使用上述转化体制造含有半乳糖的糖类的方法。

5. 发明申请

WO1998037578A1 PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE 审中-公开
标题翻译：生产半导体器件的工艺
公开(公告)号：WO1998037578A1
公开(公告)日：1998-08-27
申请号：PCT/JP1997000495
申请日：1997-02-21
申请人： ASM JAPAN K.K. , OKI ELECTRIC INDUSTRY, CO., LTD. , KOIZUMI, Satoshi , YOSHIMARU, Masaki , MORI, Yukihiro , FUKUDA, Hideaki , MATSUKI, Nobuo
发明人： ASM JAPAN K.K. , OKI ELECTRIC INDUSTRY, CO., LTD.
IPC分类号： H01L21/316
CPC分类号： H01L21/02274 , H01L21/02131 , H01L21/31625
摘要： A fluorine silicon oxide film which has a lowered hygroscopicity and an increased compression stress and a process for producing the film are disclosed. A silicon oxide film is formed on a semiconductor wafer with a plasma CVD system by using a mixed gas of a silicon source gas, a fluorine source gas, an oxidizing agent, and an inert gas. The flow rate of the inert gas is at least three times as high as that of the silicon source gas. Tetraethyl orthosilicate (TEOS) is used as the silicon source gas, and hexafluorocarbon (C2F6) is used as the fluorine source gas. Oxygen (O2) is used as the oxidizing agent, and helium (He) is used as the inert gas.
摘要翻译：公开了具有降低的吸湿性和增加的压缩应力的氟氧化硅膜和制造该膜的方法。通过使用硅源气体，氟源气体，氧化剂和惰性气体的混合气体，在等离子体CVD系统的半导体晶片上形成氧化硅膜。惰性气体的流量为硅源气体的流量的至少三倍。使用原硅酸四乙酯（TEOS）作为硅源气体，使用六氟碳（C 2 F 6）作为氟源气体。使用氧（O 2）作为氧化剂，氦（氦）用作惰性气体。

6. 发明申请

WO1997007537A1 METHOD OF PRODUCING SEMICONDUCTOR DEVICE 审中-公开
标题翻译：生产半导体器件的方法
公开(公告)号：WO1997007537A1
公开(公告)日：1997-02-27
申请号：PCT/JP1996002335
申请日：1996-08-21
申请人： ASM JAPAN K.K. , OKI ELECTRIC INDUSTRY CO., LTD. , KOIZUMI, Satoshi , YOSHIMARU, Masaki , MORI, Yukihiro , FUKUDA, Hideaki
发明人： ASM JAPAN K.K. , OKI ELECTRIC INDUSTRY CO., LTD.
IPC分类号： H01L21/316
CPC分类号： H01L21/02131 , C23C16/401 , H01L21/02274 , H01L21/31625 , H01L21/31629
摘要： A method of obtaining a highly reliable semiconductor device by decreasing hygroscopic property of an insulating film of SiOF. In manufacturing a semiconductor device using a fluorine-containing silicon oxide film as an interlayer insultating film, fluorine-containing silicon oxide film is formed in an atmosphere containing an inert gas (14) in addition to source gases (11 to 13).
摘要翻译：通过降低SiOF绝缘膜的吸湿性而获得高度可靠的半导体器件的方法。在制造使用含氟氧化硅膜作为夹层绝缘膜的半导体器件中，除了源气体（11〜13）之外，在含有惰性气体（14）的气氛中也形成含氟氧化硅膜。

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