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1. 发明专利

CA1086801A VEHICLE PROTECTION DEVICE 未知
公开(公告)号：CA1086801A
公开(公告)日：1980-09-30
申请号：CA294767
申请日：1978-01-11
申请人： KOCH KEVIN E
发明人： KOCH KEVIN E
IPC分类号： B60R19/08
摘要： A light-weight resilient vehicle protection device comprising resilient bumper bars clamped to a vehicle chassis which extend across the width of the vehicle at its front end (in some cases also at its rear end), the bumper bars being formed from transparent polycarbonate tubing, mounted in rubber.

2. 发明专利

IL173935A [6-(4-bromo-2-chlorophenylamino)-7-fluoro-3h-benzoimidazole-5-carbonyl]-aminooxy compounds 未知
公开(公告)号：IL173935A
公开(公告)日：2015-08-31
申请号：IL17393506
申请日：2006-02-26
申请人： ARRAY BIOPHARMA INC , LYSSIKATOS JOSEPH P , HURLEY BRIAN T , MARLOW ALLISON L , WALLACE ELI M , KOCH KEVIN
发明人： LYSSIKATOS JOSEPH P , HURLEY BRIAN T , MARLOW ALLISON L , WALLACE ELI M , KOCH KEVIN
IPC分类号： A61K20060101 , C07D20060101 , C07D235/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D413/04 , C07D413/06 , C07D417/06 , C07D417/12 , C07F9/6506 , C07F9/6558
摘要： Disclosed are amino acid prodrugs of compounds of the formula I and pharmaceutically acceptable salts thereof, wherein W, R1, R2, R7, R8, R9 and R10 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative disease in mammals, and pharmaceutical compositions containing such compounds.

3. 发明专利

GB2116126A Trailer 未知
公开(公告)号：GB2116126A
公开(公告)日：1983-09-21
申请号：GB8206956
申请日：1982-03-10
申请人： KOCH KEVIN ERROL
发明人： KOCH KEVIN ERROL
IPC分类号： B62D63/06 , B62D29/04
摘要： A trailer has a rectangular frame (12) formed by some of its chassis members (13) and a body (18) which comprises a moulding assembly having a base portion (19) and an upper portion (20). The base portion has a peripheral register which engages the rectangular frame and the upper portion has a peripheral zone which engages the periphery of the base portion.

4. 发明专利

FR2416140B1 未知
公开(公告)号：FR2416140B1
公开(公告)日：1981-02-27
申请号：FR7802776
申请日：1978-02-01
申请人： KOCH KEVIN
IPC分类号： B60R19/52 , B60R19/08

5. 发明专利

DE2803209C2 未知
公开(公告)号：DE2803209C2
公开(公告)日：1985-02-28
申请号：DE2803209
申请日：1978-01-25
申请人： KOCH, KEVIN ERROL, NORTH PLYMPTON, AU
发明人： KOCH, KEVIN ERROL, NORTH PLYMPTON, AU
IPC分类号： B60R19/52 , B60R19/08

6. 发明专利

SE8201502L Trailer with chassis defining rectangular frame - engaging peripheral register of base portion having flange engaged by peripheral zone of moulding assembly upper portion 未知
公开(公告)号：SE8201502L
公开(公告)日：1983-09-11
申请号：SE8201502
申请日：1982-03-10
申请人： KOCH KEVIN ERROL
发明人： KOCH KEVIN ERROL
IPC分类号： B62D63/06
摘要： The trailer includes a wheel-mounted chassis having members defining a rectangular frame. A moulding assembly mounted on the chassis includes a base portion and an upper portion. The base portion has a floor surrounded by horizontal walls and vertical walls defining a register engaged by the rectangular frame. The base portion has both upwardly extending portions and outwardly extending portions to provide strength in vertical and horizontal planes, which terminate in a peripheral flange. The upper portion has an outer peripheral zone which engages the peripheral flange of the base portion.

7. 发明专利

FR2416140A1 Motor vehicle bumper - made of parallel transparent polycarbonate tubes held by rubber blocks 未知
公开(公告)号：FR2416140A1
公开(公告)日：1979-08-31
申请号：FR7802776
申请日：1978-02-01
申请人： KOCH KEVIN
IPC分类号： B60R19/52 , B60R19/08
摘要： The front and rear bumpers of a motor vehicle consists of pairs of horizontal tubes, made of a transparent polycarbonate material and closed at the ends by caps. They are held between rubber blocks and a third rubber block fixes them on two upright tubes with a lower horizontal part. The latter is fixed by U-clamps to the car chassis. Such a bumper assembly is lightweight and does not obstruct the light from headlamps and traffic indicators. It prevents damage to the vehicle itself and to other cars when parking in confined spaces.

8. 发明申请

WO2013120603A3 STATORANORDNUNG UND ELEKTRISCHE MASCHINE 审中-公开
公开(公告)号：WO2013120603A3
公开(公告)日：2013-08-22
申请号：PCT/EP2013/000414
申请日：2013-02-13
申请人： BROSE FAHRZEUGTEILE GMBH & CO. KOMMANDITGESELLSCHAFT WÜRZBURG , KOCH, Kevin , BELZNER, Veronique , MARTIN, Christian
发明人： KOCH, Kevin , BELZNER, Veronique , MARTIN, Christian
IPC分类号： H02K3/52
摘要： Die vorliegende Erfindung betrifft eine Statoranordnung 1 für eine elektrische Maschine, mit einem Statorblechpaket 2, mit einer Vielzahl von Statorwicklungen 9, mit einer Kontaktiereinrichtung 4, welche zumindest einen Kontakt'eiter 5 aufweist, welcher dazu ausgebildet ist, zumindest zwei Statorwicklungen 9 elektrisch miteinander zu verbinden, wobei ein jeweiliger Kontaktleiter 5 zumindest eine Anschlussfahne 6 zum elektrischen Ankoppeln einer externen Anschlusseinheit an die Kontaktiereinrichtung 4 sowie zumindest einen Haken 7 zum Aufnehmen eines Wicklungsdrahtendes 14 einer jeweils mit dem Kontaktleiter 5 elektrisch verbundenen Statorwicklung 9 aufweist. Die vorliegende Erfindung betrifft eine elektrische Maschine mit einer solchen Statoranordnung.

9. 发明申请

WO2007146824A3 QUINOLINE COMPOUNDS AND METHODS OF USE 审中-公开
标题翻译：喹啉化合物和使用方法
公开(公告)号：WO2007146824A3
公开(公告)日：2008-04-10
申请号：PCT/US2007070787
申请日：2007-06-08
申请人： ARRAY BIOPHARMA INC , GENENTECH INC , GAUDINO JOHN , BOYD STEVEN ARMEN , MARLOW ALLISON L , KAPLAN TOMAS , FONG KIN CHIU , SEO JEONGBEOB , TIAN HONGQI , BLAKE JAMES , KOCH KEVIN
发明人： GAUDINO JOHN , BOYD STEVEN ARMEN , MARLOW ALLISON L , KAPLAN TOMAS , FONG KIN CHIU , SEO JEONGBEOB , TIAN HONGQI , BLAKE JAMES , KOCH KEVIN
IPC分类号： C07D215/22
CPC分类号： C07D401/14 , C07D215/22 , C07D401/12
摘要： Compounds of Formula (I), and stereoisomers, geometric isomers, tautomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof, are useful for inhibiting receptor tyrosine kinases and for treating hyperproliferative disorders mediated thereby. Methods of using compounds of Formula (I), and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
摘要翻译：式（I）化合物和立体异构体，几何异构体，互变异构体，溶剂合物，代谢物，盐和药学上可接受的前药可用于抑制受体酪氨酸激酶和治疗由此介导的过度增殖性疾病。使用式（I）化合物及其立体异构体，几何异构体，互变异构体，溶剂化物及其药学上可接受的盐在哺乳动物细胞体外，原位和体内诊断，预防或治疗这些病症或相关病理学条件被披露。

10. 发明申请

WO1996011920A1 BENZOPYRAN AND BENZO-FUSED COMPOUNDS, THEIR PREPARATION AND THEIR USE AS LEUKOTRIENE B4 (LTB4) ANTAGONISTS 审中-公开
标题翻译：苯并噻唑和苯并呋喃化合物，其制备及其作为白蛋白B4（LTB4）拮抗剂使用
公开(公告)号：WO1996011920A1
公开(公告)日：1996-04-25
申请号：PCT/IB1995000401
申请日：1995-05-26
申请人： PFIZER INC. , DOMBROSKI, Mark, A. , KOCH, Kevin , PISCOPIO, Anthony, Daniel
发明人： PFIZER INC.
IPC分类号： C07D311/56
CPC分类号： C07D311/22 , C07D311/58
摘要： This invention relates to novel benzopyran and other benzo-fused leukotriene B4 (LTB4) antagonists of formula (I), and the pharmaceutically acceptable salts thereof, wherein A is O, CH2, S, NH or N(C1-C6)alkyl; R is hydrogen or hydroxy; A is (a), (b) or (c); R is selected from the group consisting of tetrazolyl, carboxy, cis or trans -(CH2)m-CX =CX -CO2H, -(CH2)mCX X X , -CO-NG G , (d), and a substituted five or six membered aromatic ring optionally having one or two heteroatoms where the heteroatoms are optionally independently selected from the group consisting of O, S and N; R is hydrogen, fluoro, chloro, (C1-C6)alkyl, (C1-C6)alkoxy, (C1-C4)perfluoroalkyl, (C1-C4)perfluoroalkoxy, (C1-C6)alkylthio, (C1-C6)alkylsulfinyl, phenylsulfinyl, (C1-C6)alkylsulfonyl or phenylsulfonyl; to pharmaceutical compositions containing such compounds or a pharmaceutically acceptable salt thereof, and to methods of using such compounds as LTB4 antagonists. The compounds and the pharmaceutically acceptable salts of this invention inhibit the action of LTB4 and are therefore useful in the treatment of LTB4 induced illnesses such as inflammatory disorders including rheumatoid arthritis, osteoarthritis, inflammatory bowel disease, psoriasis and other skin disorders such as eczema, erythema, pruritus and acne, stroke and other forms of reperfusion injury, graft rejection, autoimmune diseases, asthma, and other conditions where marked neutrophil infiltration occurs.
摘要翻译：本发明涉及式（I）的新型苯并吡喃和其它苯并稠合白三烯B4（LTB4）拮抗剂及其药学上可接受的盐，其中A 1是O，CH 2，S，NH或N（C 1 -C 6）烷基; R 3是氢或羟基; A <2>是（a），（b）或（c）; R 1选自四唑基，羧基，顺式或反式 - （CH 2）m -C CX 1 = CX 2 -CO 2 H， - （CH 2）m C X 3 X 4 X 5，-CO-NG 1，G 2，（d）和任选具有一个或两个杂原子的取代的五元或六元芳族环，其中杂原子任选地独立地选自O，S和 N; R 2是氢，氟，氯，（C 1 -C 6）烷基，（C 1 -C 6）烷氧基，（C 1 -C 4）全氟烷基，（C 1 -C 4）全氟烷氧基，（C 1 -C 6）烷硫基，（C 1 -C 6 ）烷基亚磺酰基，苯基亚磺酰基，（C 1 -C 6）烷基磺酰基或苯基磺酰基; 涉及含有这些化合物或其药学上可接受的盐的药物组合物，以及使用这些化合物如LTB4拮抗剂的方法。本发明的化合物和药学上可接受的盐抑制LTB4的作用，因此可用于治疗LTB4诱导的疾病，例如炎症性疾病，包括类风湿性关节炎，骨关节炎，炎性肠病，牛皮癣和其它皮肤疾病如湿疹，红斑，瘙痒和痤疮，中风和其他形式的再灌注损伤，移植排斥反应，自身免疫性疾病，哮喘和其他出现明显中性粒细胞浸润的病症。

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