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    • 1. 发明申请
    • CELL-PERMEABLE RECOMBINANT PARKIN PROTEIN AND A PHARMACEUTICAL COMPOSITION FOR TREATING DEGENERATIVE BRAIN DISEASES CONTAINING THE SAME
    • 细胞可透性重组蛋白和蛋白质组合物,用于治疗含有其的变应性脑疾病
    • WO2012050402A3
    • 2012-07-26
    • PCT/KR2011007682
    • 2011-10-14
    • PROCELL THERAPEUTICS INCJO DAEWOONGKIM CHANKILIM JUNG-HEECHOI YOORIKIM HEE-HYUN
    • JO DAEWOONGKIM CHANKILIM JUNG-HEECHOI YOORIKIM HEE-HYUN
    • C07K19/00A61K38/17A61P25/28C12N15/62C12N15/63
    • C12N9/93C07K2319/10
    • The present invention relates to: a recombinant parkin protein having cell-permeable properties, wherein a macromolecule transduction domain (MTD) is fused to a degenerative-brain-disease therapeutic protein parkin; and a pharmaceutical composition or the like for treating degenerative brain diseases which contains the cell-permeable recombinant parkin protein as an active ingredient. For the recombinant parkin protein having cell-permeable properties of the present invention, a cell-permeable recombinant protein is produced in which a macromolecule transduction domain is fused to a parkin protein which is a dopamine neuron death suppression factor, and, because the same is endowed with the ability to be transmitted into cells, in use the protein is transmitted into dopamine neurons in in vitro or in vivo environments such that cell death is suppressed, or else there is a dopamine-secretion increasing effect whereby the protein can be used in studies which aim to treat Parkinson's disease, and the protein can be used to advantage as a therapeutic agent for human degenerative brain diseases.
    • 本发明涉及具有细胞渗透性质的重组帕金蛋白,其中高分子转导结构域(MTD)与退行性脑病治疗蛋白质parkin融合; 以及用于治疗退行性脑疾病的药物组合物等,其含有细胞可渗透重组帕金蛋白作为有效成分。 对于具有本发明的具有细胞渗透性质的重组帕金蛋白,产生细胞可渗透的重组蛋白,其中大分子转导结构域与作为多巴胺神经元死亡抑制因子的帕金蛋白融合,并且因为同样是 具有被传播到细胞中的能力,在使用中,蛋白质在体外或体内环境中被传播到多巴胺神经元中,使得细胞死亡被抑制,或者存在多巴胺分泌增加的作用,由此蛋白质可以用于 旨在治疗帕金森病的研究,该蛋白质可用作人退行性脑疾病的治疗剂。
    • 3. 发明公开
    • Apparatus for controlled water dripping by tensiometer
    • 控制水龙头的设备
    • KR20120072826A
    • 2012-07-04
    • KR20100134731
    • 2010-12-24
    • SHIN KUN CHULKIM HEE HYUNHAN JONG PIL
    • SHIN KUN CHULHAN JONG PILKIM HEE HYUN
    • A01G25/16A01G25/00
    • A01G25/167A01G1/00A01G27/003
    • PURPOSE: An irrigation control device using a soil moisture tension meter is provided to automatically irrigate crops by measuring the moisture tension of soil before setting the irrigation amount and interval. CONSTITUTION: An irrigation control device using a soil moisture tension meter comprises the following: a pump(20) supplying water; an electronic valve(30) combined to the pump, and opened and closed by a valve opening and closing signal outputted from a main controller(60); the soil moisture tension meter(70) measuring the moisture tension of soil; a tension sensor(80) detecting the measured moisture tension of the soil; the main controller including a memory unit, and outputting the valve opening and closing signal based on the moisture tension of the soil; the memory unit determining the irrigation time based on irrigation data including the irrigation amount and interval; and a controller reading the irrigation data from the memory unit, and adjusting the irrigation data.
    • 目的:提供使用土壤湿度张力计的灌溉控制装置,在设定灌溉量和间隔之前,通过测量土壤的水分张力来自动灌溉作物。 构成:使用土壤湿度张力计的灌溉控制装置包括:供水的泵(20); 组合到所述泵的电子阀(30),并且通过从主控制器(60)输出的开阀和关闭信号打开和​​关闭; 土壤湿度张力计(70)测量土壤的水分张力; 检测所测量的土壤湿度张力的张力传感器(80) 所述主控制器包括存储单元,并且基于所述土壤的水分张力输出所述阀开闭信号; 记录单元基于包括灌溉量和间隔在内的灌溉数据确定灌溉时间; 以及控制器,从存储器单元读取灌溉数据,以及调整灌溉数据。
    • 4. 发明申请
    • DUAL CAPACITY COMPRESSOR
    • 双能力压缩机
    • WO2005061895A1
    • 2005-07-07
    • PCT/KR2003/002821
    • 2003-12-23
    • LG ELECTRONICS INC.KIM, Jong BongKIM, Hee HyunBAE, Young JuROH, Chul Gi
    • KIM, Jong BongKIM, Hee HyunBAE, Young JuROH, Chul Gi
    • F04B49/12
    • F04B49/126F16C3/28F16H21/20
    • The present invention relates to a dual capacity compressor for preventing relative movement from taking place between components. For this, the present invention provides a dual capacity compressor including a power generating part (20) having a reversible motor (21, or 22) and a crank shaft (23) inserted in the motor (21, or 22), a compression part (30) having a cylinder (32), a piston (31), and a connecting rod (33), a crank pin (110) in an upper part of the crank shaft (23) eccentric from an axis of the crank shaft (23), an eccentric sleeve (120) rotatably fitted between the crank pin (110) and an end of the connecting rod (33), a key member (130, or 230) configured such that the key member is held at at least a part of the eccentric sleeve (120), and held at the eccentric sleeve (120) additionally during operation, for latching the eccentric sleeve (120) with the crank pin (110) positively in both direction rotation of the motor.
    • 本发明涉及一种用于防止组件之间发生相对运动的双容量压缩机。 为此,本发明提供了一种双容量压缩机,其包括具有可逆电动机(21或22)和插入电动机(21或22)中的曲轴(23)的发电部分(20),压缩部分 (30),具有圆筒(32),活塞(31)和连杆(33),曲柄销(110)在曲柄轴(23)的上部偏心于曲轴的轴线 可旋转地装配在曲柄销(110)和连接杆(33)的端部之间的偏心套筒(120),构造成使得键构件保持在至少一个 偏心套筒(120)的一部分,并且在操作期间另外保持在偏心套筒(120)处,用于在电动机的两个方向旋转时使偏心套筒(120)与曲柄销(110)正确地锁定。