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    • 5. 发明申请
    • HETEROCYCLE-FUSED THIAZOLE DERIVATIVES
    • 杂交 - 热熔化的噻唑衍生物
    • WO1997003076A1
    • 1997-01-30
    • PCT/KR1996000082
    • 1996-06-01
    • YUNGJIN PHARMACEUTICAL CO., LTD.YOO, Han, YongCHUNG, Kae, JongCHAI, Jun, PyoCHANG, Man, SikKIM, Sung, GyuCHOI, Wahn, SooKIM, Young, HunCHUN, Jae, KwangCHUNG, Young, KukKIM, Young, HeuiPAEK, Jang, HoonSEO, Kwi, HyonKANG, Dae, Pil
    • YUNGJIN PHARMACEUTICAL CO., LTD.
    • C07D513/04
    • C07D513/04C07D513/14
    • A thiazole compound represented by general formula (I), wherein R is hydrogen atom, a hydroxy group, a straight or branched C1-C6 lower alkyl group, a C1-C4 lower alkoxy group, phenyl group, a phenyl group having one to three substituents selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, fluorine, chlorine, bromine and an amino group, a C1-C5 alkylphenyl group, a phenyl group having one to three substituents selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, fluorine, chlorine, bromine and an amino group, a substituted or unsubstituted guanidino group, or an amino group having a general formula: NR3R4 in which R3 and R4, identical to or different from each other, represent independently a hydrogen atom, a C1-C6 lower alkyl group, a C3-C6 cycloalkyl group, a substituted or unsubstituted pyridyl group, a phenyl group having one to three substituents selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, a halogen atom, an amino group, a cyano group and a nitro group, a piperidine group or C1-C4 alkylpiperidine group; R1 and R2, identical to or different from each other, are independently a hydrogen atom, a hydroxy group, a C1-C6 lower alkyl group, phenyl group, a phenyl group having one substituent selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, a halogen atom, a nitro and a cyano group, a C1-C5 alkylphenyl group, or a pyridine group; R5, R6, R7 and R8, identical to or different from each other, are independently a hydrogen atom, a hydroxy group, a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, phenyl group, or a phenyl group substituted with a C1-C4 alkyl group, a C1-C4 alkoxy group or a halogen atom, or a C1-C3 alkylphenyl group; Het is a 3-, 4- or 5-membered unsaturated monocyclic group, or 6- to 12-membered unsaturated fused cyclic group, said monocyclic and fused cyclic group being comprised of one or more hetero atoms selected from oxygen, oxidative nitrogen and oxidative sulfur atom are disclosed. These compounds show excellent anti-ulcer activity.
    • 由通式(I)表示的噻唑化合物,其中R是氢原子,羟基,直链或支链C 1 -C 6低级烷基,C 1 -C 4低级烷氧基,苯基,具有1至3个 选自C1-C4低级烷基,C1-C4低级烷氧基,氟,氯,溴和氨基的取代基,C1-C5烷基苯基,具有1〜3个选自 由C1-C4低级烷基,C1-C4低级烷氧基,氟,氯,溴和氨基组成的基团,取代或未取代的胍基,或具有通式NR 3 R 4的氨基,其中R 3 和R 4彼此相同或不同,分别独立地表示氢原子,C1-C6低级烷基,C3-C6环烷基,取代或未取代的吡啶基,具有1〜3个选自 由C1-C4低级烷基组成的组 C1-C4低级烷氧基,卤素原子,氨基,氰基和硝基,哌啶基或C1-C4烷基哌啶基; R1和R2彼此相同或不同,独立地为氢原子,羟基,C1-C6低级烷基,苯基,具有一个取代基的苯基,所述取代基选自C1-C4低级 烷基,C1-C4低级烷氧基,卤素原子,硝基和氰基,C1-C5烷基苯基或吡啶基; R5,R6,R7和R8彼此相同或不同,独立地为氢原子,羟基,C1-C4低级烷基,C1-C4低级烷氧基,苯基或苯基取代 C1-C4烷基,C1-C4烷氧基或卤原子,或C1-C3烷基苯基; Het是3-,4-或5-元不饱和单环基团,或6至12元不饱和稠合环基团,所述单环和稠环基团由一个或多个选自氧,氧化氮和氧化氮的杂原子组成 硫原子。 这些化合物显示出优异的抗溃疡活性。
    • 6. 发明申请
    • THIAZOLYL TRIAZOLOTHIAZOLE DERIVATIVES
    • 三唑并噻唑衍生物
    • WO1997003073A1
    • 1997-01-30
    • PCT/KR1996000079
    • 1996-06-01
    • YUNGJIN PHARMACEUTICAL CO., LTD.YOO, Han, YongCHUNG, Kae, JongCHAI, Jun, PyoCHANG, Man, SikKIM, Sung, GyuCHOI, Wahn, SooKANG, Dae, PilKIM, Young, HunKIM, Young, HeuiWOO, Tae, WookPAEK, Jang, HoonSEO, Kwi, Hyon
    • YUNGJIN PHARMACEUTICAL CO., LTD.
    • C07D417/04
    • C07D513/04
    • Novel thiazolyl triazolothiazole derivatives represented by general formula (I); wherein, R is hydrogen atom, a hydroxy group, a straight or branched C1 - C6 lower alkyl group, a C1 - C6 lower alkoxy group, a substituted or unsubstituted phenyl or pyridyl group, a substituted or unsubstituted guanidino group, or an amino group having a general formula : NR4R5 in which R4 and R5, identical to or different from each other, represent independently hydrogen atom, a C1 - C6 lower alkyl group, a C3 - C6 cycloalkyl group, a substituted or unsubstituted phenyl or pyridyl group, a C1 - C4 lower alkyl group, a C1 - C6 lower alkoxy group, or a C1 - C4 lower alkylphenyl group; R2 and R3, identical to or different from each other, are independently hydrogen atom, a C1 - C4 lower alkyl group, or a phenyl group which may be substituted; and X and Y, different from each other, are independently nitrogen atom or a group of a formula: CR6 in which R6 is hydrogen atom, a C1 - C6 lower alkyl group, or a phenyl group which may be substituted, and pharmaceutically acceptable salts thereof are disclosed. These compounds show excellent anti-ulcer activity.
    • 由通式(I)表示的新型噻唑基三唑并噻唑衍生物; 其中,R为氢原子,羟基,直链或支链C1-C6低级烷基,C1-C6低级烷氧基,取代或未取代的苯基或吡啶基,取代或未取代的胍基或氨基 具有通式:其中R4和R5彼此相同或不同的NR4R5独立地表示氢原子,C1-C6低级烷基,C3-C6环烷基,取代或未取代的苯基或吡啶基, C1-C4低级烷基,C1-C6低级烷氧基或C1-C4低级烷基苯基; R2和R3彼此相同或不同,独立地为氢原子,C1-C4低级烷基或可被取代的苯基; 并且X和Y彼此不同,独立地为氮原子或式为CR 6的基团,其中R 6为氢原子,C 1 -C 6低级烷基或可被取代的苯基,以及药学上可接受的盐 公开。 这些化合物显示出优异的抗溃疡活性。
    • 10. 发明申请
    • VISOR CAP HAVING VARIABLE VISORS
    • VISOR CAP具有可变视力
    • WO2011010847A3
    • 2011-06-16
    • PCT/KR2010004706
    • 2010-07-19
    • KIM SUNG GYU
    • KIM SUNG GYU
    • A42B1/20A42B1/18A42B1/22
    • A42B1/065A42B1/062
    • The present invention relates to a visor cap. It is an aim of the present invention to provide a visor cap which can widen a sun blocking area through variable visors and which enables a wearer to adjust the sun-blocking area while improving wearing comfort. To accomplish the aim, provided is a visor cap including a main body, a fixed visor, and a pair of variable visors hinged to both sides of an upper surface or a lower surface of the fixed visor, so as to vary the sun-blocking area, wherein each of the pair of variable visors includes: a first variable visor portion which is made of a textile material and one side of which is fixed at an edge of the fixed visor; and a second variable visor portion which is made of a synthetic resin material and which is coupled to the other side of the first variable visor portion. The visor cap of the present invention is advantageous in that it enables a wearer to adjust the sun-blocking area if needed, and is prevented from contacting the skin of the wearer, thus improving wearing comfort while expanding the sun-blocking area.
    • 本发明涉及遮阳帽。 本发明的目的是提供一种可通过可变遮阳板加宽遮阳面积的面罩,并且能够使佩戴者在改善穿着舒适度的同时调节防晒面积。 为了达到目的,提供了一种遮阳帽,其包括主体,固定遮阳板和铰接到固定遮阳板的上表面或下表面的两侧的一对可变遮阳板,以便改变遮阳 所述一对可变面罩中的每一个包括:第一可变面罩部分,其由纺织材料制成,并且其一侧固定在所述固定遮阳板的边缘; 以及第二可变面罩部分,其由合成树脂材料制成并且联接到第一可变面罩部分的另一侧。 本发明的遮阳帽的优点在于,如果需要,其能够使穿着者调节防晒面积,并且防止与穿着者的皮肤接触,从而在扩大防晒区域的同时提高穿着舒适性。