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1. 发明申请

WO0172873A3 PROCESS FOR PRODUCING HIGH MELT FLOW POLYMERS 审中-公开
标题翻译：生产高熔体流动聚合物的方法
公开(公告)号：WO0172873A3
公开(公告)日：2002-02-28
申请号：PCT/US0109838
申请日：2001-03-28
申请人： UNION CARBIDE CHEM PLASTIC , AVGOUSTI MARIOS , KHARAZI ALEX
发明人： AVGOUSTI MARIOS , KHARAZI ALEX
IPC分类号： C08F8/50 , C08F110/06 , C08J3/12 , C08J3/20 , C08K5/14 , C08L23/00 , C08L23/02
CPC分类号： C08J3/203 , C08F8/50 , C08F110/06 , C08F2810/10 , C08J2323/02 , C08F2500/12
摘要： Disclosed is a process for making polyolefin pellet products that contain at least one unreacted free radical generator which, when heated, undergo chemical degradation producing a low viscosity polymer. The process includes contacting the polyolefin pellet with the at least one free radical generator to coat the pellet, and contacting the coated pellets and at least one unreacted free radical generator at an elevated temperature and for a period of time sufficient for the free radical initiator to soak into the interior of the pellets. The process of the invention enables the production of polyolefin pellets having any desired amount of free radical generator and therefore, production of a desired viscosity, and improves the processability of the polyolefin pellet at customer fabrication facilities to thereby provide superior quality final articles.
摘要翻译：公开了一种制备含有至少一种未反应的自由基发生剂的聚烯烃颗粒产品的方法，当加热时，其经历化学降解，产生低粘度聚合物。该方法包括使聚烯烃颗粒与至少一种自由基发生剂接触以包覆颗粒，并使涂覆的颗粒和至少一种未反应的自由基发生剂在升高的温度下接触并持续一段时间足以使自由基引发剂浸泡在颗粒的内部。本发明的方法能够生产具有任何所需量的自由基发生剂的聚烯烃颗粒，因此产生所需的粘度，并提高客户制造设备处的聚烯烃颗粒的加工性能，从而提供优质的最终制品。

2. 发明申请

WO2005123908A3 NOVEL CANCER CELL LINES AND USES THEREOF 审中-公开
公开(公告)号：WO2005123908A3
公开(公告)日：2005-12-29
申请号：PCT/US2005/020137
申请日：2005-06-08
申请人： DAUGHTERS OF CHARITY HEALTH SYSTEM EXTRAORDINARY , WISEMAN, Charles , KHARAZI, Alex
发明人： WISEMAN, Charles , KHARAZI, Alex
IPC分类号： C12N5/06 , A61K39/00
摘要： The invention provides, in part, novel SV-BR cancer cell lines. The invention provides a novel cell line SV-BR-1 deposited under ATCC ___, and SV-BR-1-GM cells deposited under ATCC ___. The invention further relates to therapeutic and non-therapeutic uses of the novel cell lines, and to use of the cell lines in the manufacture of medicaments for inducing immune responses and/or for treating tumors and cancers. Therapeutic uses include the use of SV-BR cell lines as cancer vaccines, and in particular, or the treatment of cancer.

3. 发明申请

WO2007040788A1 A METHOD TO INCREASE PRODUCTION RATE OF A CONTINUOUS MIXER OR EXTRUDER 审中-公开
标题翻译：一种提高连续混合器或挤出机生产率的方法
公开(公告)号：WO2007040788A1
公开(公告)日：2007-04-12
申请号：PCT/US2006/030122
申请日：2006-08-02
申请人： UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION , DOW GLOBAL TECHNOLOGIES INC. , ESSEGHIR, Mohamed , NEUBAUER, Anthony, C. , KHARAZI, Alex , QUARANTA, Albert, A.
发明人： ESSEGHIR, Mohamed , NEUBAUER, Anthony, C. , KHARAZI, Alex , QUARANTA, Albert, A.
IPC分类号： B29C47/10
CPC分类号： B29C47/10 , B29C47/0009 , B29C47/1027 , B29C47/1081 , B29C47/585
摘要： Compounding or extrusion rates can be increased by splitting the polymer solid feed. Melting of additional solid polymer is significantly assisted by excess enthalpy from incoming melt from a primary mixing stage. Depending on resin rheology and melting characteristics, rate increases were achieved of from up to about 55 to about 100% rate increase over the use of a single feed at the same rotor speed. The net result is a decrease in the overall SEI (specific energy input to the polymer) and thus melt temperatures.
摘要翻译：可以通过分离聚合物固体进料来增加复合或挤出速率。额外的固体聚合物的熔融显着地由来自主混合阶段的熔融物的过量焓辅助。根据树脂流变性和熔融特性，在相同转子速度下使用单一进料，实现了高达约55至约100％速率增加的速率增加。最终的结果是总体SEI（对聚合物的比能量输入）降低，从而降低熔融温度。

4. 发明申请

WO2006135454A1 NOVEL CANCER CELL LINES AND USES THEREOF 审中-公开
标题翻译：新型癌细胞系及其用途
公开(公告)号：WO2006135454A1
公开(公告)日：2006-12-21
申请号：PCT/US2005/045840
申请日：2005-12-14
申请人： DAUGHTERS OF CHARITY HEALTH SYSTEM EXTRAORDINARY , WISEMAN, Charles , KHARAZI, Alex
发明人： WISEMAN, Charles , KHARAZI, Alex
IPC分类号： C12N5/06 , A61K39/00
CPC分类号： A61K39/0011 , A61K2039/5152 , C12N5/0693
摘要： The invention provides, in part, novel SV-BR cancer cell lines. The invention provides a novel cell line SV-BR-1 deposited under ATCC, and SV-BR-1-GM cells deposited under ATCC. The invention further relates to therapeutic and non-therapeutic uses of the novel cell lines, and to use of the cell lines in the manufacture of medicaments for inducing immune responses and/or for treating tumors and cancers. Therapeutic uses include the use of SV-BR cell lines as cancer vaccines, and in particular, or the treatment of cancer.
摘要翻译：本发明部分地提供新型SV-BR癌细胞系。本发明提供了保藏在ATCC下的新型细胞系SV-BR-1和保藏在ATCC下的SV-BR-1-GM细胞。本发明还涉及新型细胞系的治疗和非治疗用途，以及细胞系在制备用于诱导免疫应答和/或治疗肿瘤和癌症的药物中的用途。治疗用途包括使用SV-BR细胞系作为癌症疫苗，特别是或治疗癌症。

5. 发明申请

WO2005123908A2 NOVEL CANCER CELL LINES AND USES THEREOF 审中-公开
标题翻译：新型癌细胞系及其用途
公开(公告)号：WO2005123908A2
公开(公告)日：2005-12-29
申请号：PCT/US2005020137
申请日：2005-06-08
申请人： DAUGHTERS OF CHARITY HEALTH SY , WISEMAN CHARLES , KHARAZI ALEX
发明人： WISEMAN CHARLES , KHARAZI ALEX
IPC分类号： A61K39/00 , A61P35/00 , C12N5/08
CPC分类号： A61K39/0011 , A61K2039/5152 , A61K2039/5156 , A61K2039/55522
摘要： The invention provides, in part, novel SV-BR cancer cell lines. The invention provides a novel cell line SV-BR-1 deposited under ATCC ___, and SV-BR-1-GM cells deposited under ATCC ___. The invention further relates to therapeutic and non-therapeutic uses of the novel cell lines, and to use of the cell lines in the manufacture of medicaments for inducing immune responses and/or for treating tumors and cancers. Therapeutic uses include the use of SV-BR cell lines as cancer vaccines, and in particular, or the treatment of cancer.
摘要翻译：本发明部分地提供新型SV-BR癌细胞系。本发明提供了保藏在ATCC ___下的新型细胞系SV-BR-1，以及保藏在ATCC ___下的SV-BR-1-GM细胞。本发明还涉及新型细胞系的治疗和非治疗用途，以及细胞系在制备用于诱导免疫应答和/或治疗肿瘤和癌症的药物中的用途。治疗用途包括使用SV-BR细胞系作为癌症疫苗，特别是或治疗癌症。

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