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1. 发明授权

EP1485376B1 COMPOSITIONS USEFUL AS INHIBITORS OF PROTEIN KINASES 有权
标题翻译：作为激酶蛋白抑制剂的组合物
公开(公告)号：EP1485376B1
公开(公告)日：2007-06-27
申请号：EP03716598.2
申请日：2003-03-14
申请人： VERTEX PHARMACEUTICALS INCORPORATED , Binch, Hayley , Charrier, Jean-Damien , Everitt, Simon , Golec, Julian, M. C. , Kay, David , Knegtel, Ronald , Miller, Andrew , Pierard, Françoise , Pierce, Albert C.
发明人： BEBBINGTON, David
IPC分类号： C07D403/12 , C07D417/12 , C07D413/12 , C07D471/04 , C07D487/04 , A61K31/517 , A61P35/00
CPC分类号： C07D403/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

2. 发明公开

EP1485376A1 COMPOSITIONS USEFUL AS INHIBITORS OF PROTEIN KINASES 有权
标题翻译：作为激酶蛋白抑制剂的组合物
公开(公告)号：EP1485376A1
公开(公告)日：2004-12-15
申请号：EP03716598.2
申请日：2003-03-14
申请人： Vertex Pharmaceuticals Incorporated , Binch, Hayley , Charrier, Jean-Damien , Everitt, Simon , Golec, Julian, M. C. , Kay, David , Knegtel, Ronald , Miller, Andrew , Pierard, Françoise , Pierce, Albert C.
发明人： BEBBINGTON, David
IPC分类号： C07D403/12 , C07D417/12 , C07D413/12 , C07D471/04 , C07D487/04 , A61K31/517 , A61P35/00
CPC分类号： C07D403/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

3. 发明公开

EP3320324A1 DROP WEIGHT TOWER FOR CRACK INITIATION IN FRACTURE MECHANICS SAMPLES 审中-公开
标题翻译：用于裂纹力学样本中裂纹初始化的重量塔
公开(公告)号：EP3320324A1
公开(公告)日：2018-05-16
申请号：EP16748382.5
申请日：2016-07-08
申请人： SABIC Global Technologies B.V. , Kay, David
发明人： KAY, David , BAJAJ, Devendra
IPC分类号： G01N3/303
CPC分类号： G01N3/303 , G01N2203/0033 , G01N2203/006 , G01N2203/0064
摘要： Drop-weight tower (110) for reproducibly initiating a crack in a material sample for fracture mechanics testing comprising a base (120) with a top surface upon which a sample holder (124) is mounted to grip a material sample, an attachment column (140) having a linear rail (142), a carriage (162) attached to the linear rail (142) and a stage (164) is attached to the carriage. The stage (164) includes a vertical rod (184) and a razor-blade holder (178). A weight is slidably mounted to the vertical rod (184). The carriage is used to adjust the height of the stage (164) relative to the material sample. A hammer (180) slides up and down the vertical rod (184) to apply consistent and reproducible force on the razor (178) that then initiates the crack in the material sample.

4. 发明公开

EP0168248A3 A programmed learning text 失效
标题翻译：编程学习文本
公开(公告)号：EP0168248A3
公开(公告)日：1988-09-21
申请号：EP85304936
申请日：1985-07-10
申请人： Kay, Andrew F. , Kay, David A.
发明人： Kay, Andrew F.
IPC分类号： G09B03/06
CPC分类号： G09B3/085 , G09B21/003
摘要： A programmed learning text including self-test questions for providing immediate feedback to the student on what he has learned. Each question is followed by a plurality of possible answers. Adjacent to each such possible answer is a mottled design printed on the paper. Indentations in the paper, which indentations are concealed by the mottled design, distinguish the correct answer from the wrong answers. After selecting one of the choices, the student touches the mottled design to find out whether his choice is the correct one.
摘要翻译：一个编程的学习文本，包括自我测试的问题，以便立即向学生反馈他所学到的知识。每个问题后面都有多个可能的答案。与每个这样可能的答案相邻是印在纸上的斑驳设计。本文中的缩进，凹痕由斑驳的设计隐藏，区分正确的答案与错误的答案。选择其中一个选择后，学生会触摸斑驳的设计，以了解他的选择是否正确。

5. 发明授权

EP3320324B1 DROP WEIGHT TOWER FOR CRACK INITIATION IN FRACTURE MECHANICS SAMPLES 有权
公开(公告)号：EP3320324B1
公开(公告)日：2019-05-01
申请号：EP16748382.5
申请日：2016-07-08
申请人： SABIC Global Technologies B.V. , Kay, David
发明人： KAY, David , BAJAJ, Devendra
IPC分类号： G01N3/303

6. 发明公开

EP0168248A2 A programmed learning text 失效
标题翻译：程序员Lerntext。
公开(公告)号：EP0168248A2
公开(公告)日：1986-01-15
申请号：EP85304936.9
申请日：1985-07-10
申请人： Kay, Andrew F. , Kay, David A.
发明人： Kay, Andrew F. , Kay, David A.
IPC分类号： G09B3/06
CPC分类号： G09B3/085 , G09B21/003
摘要： A programmed learning text including self-test questions for providing immediate feedback to the student on what he has learned. Each question is followed by a plurality of possible answers. Adjacent to each such possible answer is a mottled design printed on the paper. Indentations in the paper, which indentations are concealed by the mottled design, distinguish the correct answer from the wrong answers. After selecting one of the choices, the student touches the mottled design to find out whether his choice is the correct one.
摘要翻译：一个编程的学习文本，包括自我测试的问题，以便立即向学生反馈他所学到的知识。每个问题后面都有多个可能的答案。与每个这样可能的答案相邻是印在纸上的斑驳设计。本文中的缩进，凹痕由斑驳的设计隐藏，区分正确的答案与错误的答案。选择其中一个选择后，学生会触摸斑驳的设计，以了解他的选择是否正确。

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