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1. 发明申请

WO2009076673A3 LIGAND CONJUGATED THERMOTHERAPY SUSCEPTORS AND METHODS FOR PREPARING SAME 审中-公开
公开(公告)号：WO2009076673A3
公开(公告)日：2009-06-18
申请号：PCT/US2008/086855
申请日：2008-12-15
申请人： ADURO BIOTECH , IVKOV, Robert , GRUTTNER, Cordula , MULLER, Knut , TELLER, Joachim , WESTPHAL, Fritz , FOREMAN, Allan , KANNE, David, B. , CHIN, Hsiao-Ling , CHINN, Paul, C.
发明人： IVKOV, Robert , GRUTTNER, Cordula , MULLER, Knut , TELLER, Joachim , WESTPHAL, Fritz , FOREMAN, Allan , KANNE, David, B. , CHIN, Hsiao-Ling , CHINN, Paul, C.
IPC分类号： G01N33/553
摘要： Magnetic nanoparticles exhibiting enhanced heating ability in thermotherapeutic applications are described, as are several strategies to conjugate such nanoparticles. Methods for using conjugated nanoparticles are also provided.

2. 发明申请

WO1996017829A3 3-BENZOYLPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES 审中-公开
公开(公告)号：WO1996017829A3
公开(公告)日：1996-06-13
申请号：PCT/US1995015840
申请日：1995-12-06
申请人： ZENECA LIMITED , KANNE, David, B.
发明人： ZENECA LIMITED
IPC分类号： C07D213/69

3. 发明申请

WO9617829A2 3-BENZOYLPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES 审中-公开
标题翻译： 3-苯甲酰吡啶衍生物，其制备及其作为除草剂的用途
公开(公告)号：WO9617829A2
公开(公告)日：1996-06-13
申请号：PCT/US9515840
申请日：1995-12-06
申请人： ZENECA LTD , KANNE DAVID B
发明人： KANNE DAVID B
IPC分类号： C07D213/68 , A01N25/08 , A01N43/40 , C07D213/61 , C07D213/64 , C07D213/69
CPC分类号： C07D213/64 , A01N43/40 , C07D213/61 , C07D213/69
摘要： Herbicidal compounds have formula (I) in which: R1 is hydrogen, halogen, C1-C4 alkyl; C1-C4 haloalkyl; C1-C4 alkoxy; C1-C4 haloalkoxy; C2-C8 alkoxyalkyl; nitro; cyano; thiocyano; or R7S(O)m- where m is 0, 1 or 2, and R7 is C1-C4 alkyl or C1-C4 haloalkyl; R2 and R3 are independently hydrogen; halogen; C1-C4 alkyl; C1-C4 alkoxy; C1-C4 haloalkyl; C1-C4 haloalkoxy; C2-C8 alkoxyalkyl; nitro; R8S(O)2O- or R8S(O)n- where n is 0, 1 or 2 and R8 is C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 cyanoalkyl, phenyl or benzyl; NR9R10 where R9 and R10 are independently hydrogen or C1-C4 alkyl; R11CO- where R11 is C1-C4 alkyl or C1-C4 alkoxy, SO2NR12R13 where R12 and R13 are independently hydrogen, C1-C4 alkyl or C1-C4 haloalkyl, or N(R14)COR15 where R14 and R15 are independently hydrogen or C1-C4 alkyl; R4 is hydrogen, halogen or hydroxy; R5 is hydrogen, methyl or trifluoromethyl; and R6 is hydrogen, halogen or hydroxy; provided that R4 and R6 are not both hydrogen; and agriculturally acceptable salts thereof.
摘要翻译：除草化合物具有式（I），其中：R 1是氢，卤素，C 1 -C 4烷基; C 1 -C 4卤代烷基; C1-C4烷氧基; C1-C4卤代烷氧基; C2-C8烷氧基烷基; 硝基; 氰基; 氰硫基; 或R 7 S（O）m - ，其中m为0,1或2，并且R 7为C 1 -C 4烷基或C 1 -C 4卤代烷基; R2和R3独立地是氢; 卤素; C 1 -C 4烷基; C1-C4烷氧基; C 1 -C 4卤代烷基; C1-C4卤代烷氧基; C2-C8烷氧基烷基; 硝基; 其中n为0,1或2，R8为C1-C4烷基，C1-C4卤代烷基，C1-C4氰基烷基，苯基或苄基; R8S（O）2O-或R8S（O） NR 9 R 10，其中R 9和R 10独立地是氢或C 1 -C 4烷基; R11CO-，其中R11是C1-C4烷基或C1-C4烷氧基，SO2NR12R13，其中R12和R13独立地是氢，C1-C4烷基或C1-C4卤代烷基，或N（R14）COR15，其中R14和R15独立地是氢或C1- C4烷基; R4是氢，卤素或羟基; R5是氢，甲基或三氟甲基; R6为氢，卤素或羟基; 条件是R4和R6不同时为氢; 及其农业上可接受的盐。

4. 发明申请

WO2006044975A3 COMPOSITIONS AND THEIR USE AS ANTI-TUMOR AGENTS 审中-公开
标题翻译：组合物及其作为抗肿瘤药物的用途
公开(公告)号：WO2006044975A3
公开(公告)日：2006-09-28
申请号：PCT/US2005037618
申请日：2005-10-18
申请人： COMPASS PHARMACEUTICALS LLC , KANNE DAVID , WARD JOHN , LOOK GARY , WANG X MICHAEL , CHAN DIVA , LEE TINA , JAMES DONALD , GLESS RICHARD , SCHULLEK JOHN , VACIN CHARLES
发明人： KANNE DAVID , WARD JOHN , LOOK GARY , WANG X MICHAEL , CHAN DIVA , LEE TINA , JAMES DONALD , GLESS RICHARD , SCHULLEK JOHN , VACIN CHARLES
IPC分类号： C07D401/12 , A61K31/34 , A61K31/42 , A61K31/44 , A61K31/444 , C07D207/09 , C07D209/20 , C07D213/74 , C07D239/42 , C07D241/20 , C07D253/06 , C07D261/14 , C07D277/06 , C07D307/14 , C07D307/52
CPC分类号： C07D213/75 , C07C233/65 , C07C233/81 , C07D213/74 , C07D239/42 , C07D253/07
摘要： The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreating carcinomas) and mesotheliomas.
摘要翻译：本发明提供了新化合物及其药物组合物，以及使用该化合物和药物组合物治疗肿瘤的方法。化合物可用于治疗的特定肿瘤类型的实例包括但不限于肉瘤，黑素瘤，神经母细胞瘤，癌（包括但不限于肺癌，肾细胞癌，卵巢癌，肝癌，膀胱癌和胰腺癌）和间皮瘤。

5. 发明申请

WO2006044975A2 COMPOSITIONS AND THEIR USE AS ANTI-TUMOR AGENTS 审中-公开
标题翻译：组合物及其作为抗肿瘤剂的用途
公开(公告)号：WO2006044975A2
公开(公告)日：2006-04-27
申请号：PCT/US2005/037618
申请日：2005-10-18
申请人： COMPASS PHARMACEUTICALS LLC , KANNE, David , WARD, John , LOOK, Gary , WANG, X., Michael , CHAN, Diva , LEE, Tina , JAMES, Donald , GLESS, Richard , SCHULLEK, John , VACIN, Charles
发明人： KANNE, David , WARD, John , LOOK, Gary , WANG, X., Michael , CHAN, Diva , LEE, Tina , JAMES, Donald , GLESS, Richard , SCHULLEK, John , VACIN, Charles
CPC分类号： C07D213/75 , C07C233/65 , C07C233/81 , C07D213/74 , C07D239/42 , C07D253/07
摘要： The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreating carcinomas) and mesotheliomas.
摘要翻译：本发明提供新的化合物及其药物组合物，以及使用该化合物和药物组合物治疗肿瘤的方法。化合物可用于治疗的特定肿瘤类型的实例包括但不限于肉瘤，黑素瘤，成神经细胞瘤，癌（包括但不限于肺，肾细胞，卵巢，肝，膀胱和胰腺癌）和间皮瘤。

6. 发明申请

WO2011146837A8 SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME 审中-公开
标题翻译：平衡和异构体组合物及其制备方法
公开(公告)号：WO2011146837A8
公开(公告)日：2012-11-08
申请号：PCT/US2011037341
申请日：2011-05-20
申请人： AMYRIS INC , FISHER KARL , SCHOFER SUSAN JESSICA , KANNE DAVID B
发明人： FISHER KARL , SCHOFER SUSAN JESSICA , KANNE DAVID B
IPC分类号： C07C2/04 , C07C9/22 , C07C11/21 , C10M127/02
CPC分类号： C10M105/04 , C07C2/04 , C07C9/22 , C07C2531/28 , C07C2531/30 , C07C2531/38 , C10M2203/0206 , C10M2205/028 , C10M2207/282 , C10M2209/084 , C10N2230/02 , C10N2240/04 , C10N2240/08 , C10N2240/10 , C10N2240/14 , C10N2240/30 , C10N2240/40 , C07C11/21
摘要： Provided herein are methods comprising catalytic dimerization of ß-farnesene to obtain squalane and/or isosqualane. Compositions comprising squalane and/or isosqualane are provided. In certain embodiments, squalane and isosqualane prepared by the methods provided herein can be useful for applications in cosmetic industry and/or in the lubricants industry.
摘要翻译：本文提供了包含β-法呢烯的催化二聚作用以获得角鲨烷和/或异山梨醇的方法。提供了包含角鲨烷和/或异冠醚的组合物。在某些实施方案中，通过本文提供的方法制备的角鲨烷和异屈五氮烷可用于化妆品工业和/或润滑剂工业中的应用。

7. 发明申请

WO2011146837A1 SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME 审中-公开
标题翻译：平衡和异构体组合物及其制备方法
公开(公告)号：WO2011146837A1
公开(公告)日：2011-11-24
申请号：PCT/US2011/037341
申请日：2011-05-20
申请人： AMYRIS, INC. , FISHER, Kerl , SCHOFER, Susan, Jessica , KANNE, David, B.
发明人： FISHER, Kerl , SCHOFER, Susan, Jessica , KANNE, David, B.
IPC分类号： C07C2/04 , C07C9/22 , C07C11/21 , C10M127/02
CPC分类号： C10M105/04 , C07C2/04 , C07C9/22 , C07C2531/28 , C07C2531/30 , C07C2531/38 , C10M2203/0206 , C10M2205/028 , C10M2207/282 , C10M2209/084 , C10N2230/02 , C10N2240/04 , C10N2240/08 , C10N2240/10 , C10N2240/14 , C10N2240/30 , C10N2240/40 , C07C11/21
摘要： Provided herein are methods comprising catalytic dimerization of β-farnesene to obtain squalane and/or isosqualane. Compositions comprising squalane and/or isosqualane are provided. In certain embodiments, squalane and isosqualane prepared by the methods provided herein can be useful for applications in cosmetic industry and/or in the lubricants industry.
摘要翻译：本文提供了包含β-法呢烯的催化二聚作用以获得角鲨烷和/或异山梨醇的方法。提供了包含角鲨烷和/或异冠醚的组合物。在某些实施方案中，通过本文提供的方法制备的角鲨烷和异屈五氮烷可用于化妆品工业和/或润滑剂工业中的应用。

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