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1. 发明申请

US20070218566A1 Method and Device for Improved Purification of a Substance Bound to Paramagnetic Microparticles 审中-公开
标题翻译：用于改善对顺磁性微粒的物质净化的方法和装置
公开(公告)号：US20070218566A1
公开(公告)日：2007-09-20
申请号：US10580066
申请日：2004-11-16
申请人： Roland Barten , Marion Kramer , Jurgen Krause , Sandra Strich , Anja Weiland
发明人： Roland Barten , Marion Kramer , Jurgen Krause , Sandra Strich , Anja Weiland
IPC分类号： G01N33/553
CPC分类号： G01N33/54326 , B03C1/01 , B03C1/0332 , B03C1/288 , B03C2201/18
摘要： The invention relates to a method for improved cleaning of a first substance which is bound to paramagnetic microparticles. Said microparticles are suspended in a first liquid. The inventive method comprises the following steps: a) microparticles are exposed to a first magnetic field in a first container so that they are securely maintained and are prevented from being washed away by a flow of the first liquid, and b) after step a), at least one part of the first liquid is guided through the line in a first direction of the first line and through another section, and in the second section, said part is exposed to a second or to the first magnetic field in order to hold onto the washed away microparticles. In the section, the surface of the cross section of the first line is enlarged. The second or first magnetic field inside the section has a larger cross-sectional field strength than the first magnetic field inside the first container.
摘要翻译：本发明涉及一种用于改进与顺磁性微粒结合的第一物质的清洁的方法。所述微粒悬浮在第一液体中。本发明的方法包括以下步骤：a）微粒暴露于第一容器中的第一磁场，使得它们被牢固地保持并被防止被第一液体的流动洗掉，以及b）在步骤a）之后，第一液体的至少一部分沿着第一线的第一方向被引导通过另一部分，并且在第二部分中，所述部分暴露于第二或第一磁场，以便保持到被洗掉的微粒上。在该部分中，第一行的横截面的表面被放大。该部分内的第二或第一磁场具有比第一容器内部的第一磁场更大的横截面场强。

2. 发明授权

US5233020A Paint binders 失效
标题翻译：涂料粘合剂
公开(公告)号：US5233020A
公开(公告)日：1993-08-03
申请号：US721514
申请日：1991-07-12
申请人： Brigitte Hase , Ulrich Eicken , Herbert Fischer , Horst-Jurgen Krause , Wolfgang Gress , Norbert Stork
发明人： Brigitte Hase , Ulrich Eicken , Herbert Fischer , Horst-Jurgen Krause , Wolfgang Gress , Norbert Stork
IPC分类号： C08G73/02 , C08G73/04 , C09D7/12 , C09D167/00 , C09D167/02 , C09D179/00 , C09D179/02
CPC分类号： C09D179/02 , C08G73/0233 , C09D7/125 , C08L79/02 , C08L79/08
摘要： Poly-N-acylalkyleneimines corresponding to the following formula ##STR1## are used as an oxidatively crosslinking constituent in paints. In formula (I), R--CO represents the acyl radical of a mono- or polyunsaturated, aliphatic C.sub.16-22 carboxylic acid or a mixture of such radicals, R'--CO represents the acyl radical of a C.sub.1-22 carboxylic acid or a mixture of such radicals and x and y represent the percentages by weight of the particular polymer units, x assuming values of 20 to 100% and preferably 20 to 95% and y assuming values of 80 to 0% and preferably 80 to 5%. The indices m and n independently of one another may assume the value 2 or 3.
摘要翻译： PCT No.PCT / EP90 / 00019 Sec。 371日期1991年7月12日 102（e）日期1991年7月12日PCT 1990年1月5日PCT PCT。出版物WO90 / 08175 日期：1990年7月26日。对应于下式的聚N-酰基亚烷基亚胺（I）用作涂料中的氧化交联成分。在式（I）中，R-CO表示单或多不饱和的脂族C 16-22羧酸或这些基团的混合物的酰基，R'-CO表示C1-22羧酸的酰基或这些基团的混合物和x和y表示特定聚合物单元的重量百分比，假设值为20至100％，优选为20至95％，y为假定值为80至0％，优选为80至5％。指数m和n彼此独立地可以取值2或3。

3. 发明授权

US5188940A Method of determining the total fibrinolytic activity in the plasma 失效
标题翻译：确定等离子体中的总纤维素活性的方法
公开(公告)号：US5188940A
公开(公告)日：1993-02-23
申请号：US463177
申请日：1990-01-10
申请人： Jurgen Krause , Walter Haarmann
发明人： Jurgen Krause , Walter Haarmann
IPC分类号： C12Q1/37 , C12Q1/56 , G01N33/86
CPC分类号： G01N33/86 , C12Q1/56 , G01N2333/75 , G01N2333/968 , G01N2333/9726
摘要： A method of determining the total fibrinolytic activity in plasma, is characterized in thata) a quantity of fibrin sufficient to produce turbidity is added to a dilute platelet poor plasma sample or is produced in situ and the time dependent change in turbidity or the time-dependent formation of fibrin cleavage products is measured; orb) a chromogenic plasmin substrate and a quantity of fibrin, fibrinogen cleavage products or an enzyme which produces fibrin in situ, insufficient to produce turbidity, is added to a dilute platelet poor plasma sample and the time dependent color formation is measured.
摘要翻译：确定血浆中总的纤维蛋白溶解活性的方法的特征在于：a）足以产生浊度的纤维蛋白量被加入稀释的血小板贫血血浆样品中，或者原位产生，并且浊度或时间依赖性时间依赖性变化，测量纤维蛋白裂解产物的依赖性形成; 或b）色素性纤溶酶底物和一定量的纤维蛋白，纤维蛋白原裂解产物或原位产生纤维蛋白的酶，不足以产生浊度，加入稀释的血小板不良血浆样品中，并测量时间依赖性色素形成。

4. 发明授权

US4897557A Electronic control system, in particular for a printer 失效
标题翻译：电子控制系统，特别是打印机
公开(公告)号：US4897557A
公开(公告)日：1990-01-30
申请号：US163764
申请日：1988-03-07
申请人： Jurgen Krause
发明人： Jurgen Krause
IPC分类号： H02H3/10 , B41J2/30 , H02H3/00 , H02H3/087 , H02H7/20 , H03K17/08 , H03K17/082
CPC分类号： H03K17/0826 , H02H3/087 , Y10T307/911 , Y10T307/918
摘要： Such electronic control systems contain safety circuits for device components endangered by excessive currents or excessive voltages, which are constructed only for a pulse operation and not for higher relative switch-on times.In order to shield the effectors (users) already in the pre-stage against undesirable high currents or, respectively, voltages, such that a punch through of these destroying voltages or, respectively, currents can be excluded for practical purposes, it is disclosed that an effector (1) is controllable in operating condition and simultaneously a reference voltage (R1/R2) can be switched on within the permissible tolerance region where, upon the exceeding of the tolerance region, the effector (1) can be switched off.
摘要翻译： PCT No.PCT / DE87 / 00274 Sec。 371日期：1988年3月7日 102（e）1988年3月7日PCT申请1987年6月12日PCT公开号公开号WO87 / 07987 日期为1987年12月30日。这种电子控制系统包含由过电流或过电压濒危的器件组件的安全电路，其仅用于脉冲操作而不是用于较高的相对接通时间。为了屏蔽已经处于前期阶段的效应器（用户），防止不希望的高电流或分别使电压使得这些破坏电压的冲击或分别用于实际目的的电流被排除在外效应器（1）在操作条件下是可控的，并且同时可以在容许公差区域内接通参考电压（R1 / R2），其中超过公差区域时，效应器（1）可以被关闭。

5. 发明授权

US5788004A Power control system for motor vehicles with a plurality of power-converting components 失效
标题翻译：具有多个电力转换部件的机动车辆的动力控制系统
公开(公告)号：US5788004A
公开(公告)日：1998-08-04
申请号：US598853
申请日：1996-02-09
申请人： Siegfried Friedmann , Karl Brinz , Michael Preis , Georg Goetz , Jurgen Krause
发明人： Siegfried Friedmann , Karl Brinz , Michael Preis , Georg Goetz , Jurgen Krause
IPC分类号： B60K6/48 , B60L15/20 , B60W10/06 , B60W10/08 , B60W10/26 , B60W20/00 , F02D41/14 , F02D41/30 , H02J7/14 , B60K1/00
CPC分类号： B60W20/10 , B60K6/48 , B60L15/2045 , B60W10/06 , B60W10/08 , B60W10/26 , B60W20/00 , F02D41/1406 , F02D41/3005 , H02J7/1446 , B60W2510/244 , F02D2250/18 , Y02T10/56 , Y02T10/6221 , Y02T10/6286 , Y02T10/645 , Y02T10/7005 , Y02T10/7022 , Y02T10/7283
摘要： In a power control system for motor vehicles with a plurality of power-converting elements as well as sensors for determining the efficiency of the individual elements, a processor determines the overall system efficiency from the efficiencies of the individual components, and calculates and adjusts a value for a parameter that influences the efficiency of at least one component to achieve an optimum total efficiency. Surplus power is used to charge an energy storage device. Preferably the parameters that influence the efficiency, whose values are adjusted to achieve an optimum total efficiency, are the power, or a parameter that is proportional to the power, that is to be delivered by a power-generating component, and/or the rpm or a parameter that is proportional to the rpm of a component.
摘要翻译：在具有多个功率转换元件的机动车辆的功率控制系统以及用于确定各个元件的效率的传感器中，处理器根据各个部件的效率确定整个系统效率，并且计算和调整值用于影响至少一个组件的效率以达到最佳总效率的参数。剩余电力用于对能量存储装置充电。优选地，影响效率的参数（其值被调整以达到最佳总效率）是功率或与功率成比例的参数，其将由发电部件传递，和/或转速或与组件的rpm成比例的参数。

7. 发明授权

US3956382A Process for the production of ether polycarboxylic acids 失效
标题翻译：生产醚多元羧酸的方法
公开(公告)号：US3956382A
公开(公告)日：1976-05-11
申请号：US516209
申请日：1974-10-21
申请人： Horst-Jurgen Krause
发明人： Horst-Jurgen Krause
IPC分类号： C07C59/305 , B01J23/00 , C07B61/00 , C07C51/00 , C07C51/15 , C07C67/00 , C07C59/22
CPC分类号： C07C51/15 , Y02P20/582
摘要： A process for the production of ether polycarboxylic acids comprising reacting alkali metal salts of ether carboxylic acids with carbon dioxide in the presence of (1) an alkaline compound selected from the group of alkali metal carbonates, bicarbonates and hydroxides and (2) optionally, heavy metal catalysts and inert diluents at temperatures of 200.degree.C to 350.degree.C under pressure, acidify the resulting alkali metal salt of an ether polycarboxylic acid and recovering said ether polycarboxylic acid.
摘要翻译：一种制备醚多元羧酸的方法，包括在（1）选自碱金属碳酸盐，碳酸氢盐和氢氧化物的碱性化合物的存在下，使醚羧酸的碱金属盐与二氧化碳反应，和（2）任选的重质金属催化剂和惰性稀释剂在200-350℃的压力下酸化所得到的醚多元羧酸的碱金属盐，并回收所述的醚多元羧酸。

8. 发明申请

US20070125918A1 Benchtop product securing device 审中-公开
标题翻译：台式产品固定装置
公开(公告)号：US20070125918A1
公开(公告)日：2007-06-07
申请号：US11295076
申请日：2005-12-06
申请人： Jurgen Krause , Robert Schultz , Winston Webb
发明人： Jurgen Krause , Robert Schultz , Winston Webb
IPC分类号： F16M11/20
CPC分类号： F16M13/02 , B01L9/50 , B25H1/10 , F16M11/22
摘要： A benchtop securing device for securing objects to a table is provided. The benchtop securing device comprises a mounting plate having a table engaging surface adapted to abut a surface of a table, the mounting plate further having an object attaching surface adapted to mount an object thereon, and a sloped member having a sloping surface, the sloped member further being coupled to the mounting plate such that the table can be received between the mounting plate and the sloping surface of the sloped member. The benchtop securing device further comprises a sliding block having a sliding surface that has a slope that substantially matches the slope of the sloping surface of the sloped member, wherein when the sliding surface of the sliding block engages the sloping surface of the sloped member the benchtop securing device becomes securely attached to the table.
摘要翻译：提供了一种用于将物体固定到工作台上的台面固定装置。所述台式固定装置包括安装板，所述安装板具有适于邻接工作台表面的工作台接合表面，所述安装板还具有适于安装物体的物体安装表面和具有倾斜表面的倾斜部件，所述倾斜部件进一步联接到安装板，使得工作台可以容纳在安装板和倾斜构件的倾斜表面之间。台式固定装置还包括具有滑动表面的滑动块，滑动表面具有与倾斜构件的倾斜表面的斜率基本一致的斜面，其中当滑动块的滑动表面接合倾斜构件的倾斜表面时，台面固定装置牢固地固定在工作台上。

9. 发明申请

US20060222569A1 Device and method for the preparation of analyte comprising liquids 审中-公开
标题翻译：用于制备包含液体的分析物的装置和方法
公开(公告)号：US20060222569A1
公开(公告)日：2006-10-05
申请号：US10553999
申请日：2004-04-19
申请人： Roland Barten , Jurgen Krause , Hans Kosak
发明人： Roland Barten , Jurgen Krause , Hans Kosak
IPC分类号： B01L3/00
CPC分类号： B01L3/502 , B01L2200/026 , B01L2200/0668 , B01L2200/10 , B01L2200/16 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2400/0478 , B01L2400/0655 , G01N1/28
摘要： The present invention relates to a device, a kit and a method for the contamination-free preparation of analyte, in particular biopolymer comprising liquids. The device comprises wo chambers (2, 3) having a reversibly changeable volume.
摘要翻译：本发明涉及用于无污染制备分析物的装置，试剂盒和方法，特别是包含液体的生物聚合物。该装置包括具有可逆变化体积的窝室（2,3）。

10. 发明授权

US5807875A Amino acid derivatives, pharmaceutical compositions containing these compounds and processes for preparing them 失效
标题翻译：氨基酸衍生物，含有这些化合物的药物组合物及其制备方法
公开(公告)号：US5807875A
公开(公告)日：1998-09-15
申请号：US763504
申请日：1996-12-11
申请人： Klaus Rudolf , Wolfgang Eberlein , Wolfhard Engel , Gerhard Mihm , Henri Doods , Heike Andrea Wieland , Klaus-Dieter Willim , Jurgen Krause , Horst Dollinger , Franz Esser , Gerd Schnorrenberg , Michael Entzeroth , Wolfgang Wienen
发明人： Klaus Rudolf , Wolfgang Eberlein , Wolfhard Engel , Gerhard Mihm , Henri Doods , Heike Andrea Wieland , Klaus-Dieter Willim , Jurgen Krause , Horst Dollinger , Franz Esser , Gerd Schnorrenberg , Michael Entzeroth , Wolfgang Wienen
IPC分类号： A61K31/155 , A61K31/165 , A61K31/195 , A61K31/198 , A61K31/38 , A61K31/381 , A61K31/40 , A61K31/403 , A61K31/404 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/4245 , A61K31/44 , A61K31/4409 , A61K31/4418 , A61K31/4427 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/454 , A61K31/47 , A61K38/00 , A61P9/12 , A61P43/00 , C07C237/22 , C07C237/42 , C07C255/60 , C07C257/12 , C07C257/14 , C07C257/18 , C07C259/10 , C07C259/18 , C07C261/04 , C07C275/40 , C07C279/10 , C07C279/12 , C07C279/14 , C07C279/18 , C07C279/36 , C07C307/02 , C07C307/10 , C07C311/08 , C07C311/15 , C07C311/19 , C07C311/39 , C07C311/42 , C07D209/14 , C07D209/16 , C07D209/42 , C07D209/44 , C07D211/28 , C07D213/38 , C07D213/55 , C07D215/12 , C07D215/38 , C07D223/20 , C07D233/24 , C07D233/48 , C07D233/54 , C07D233/64 , C07D233/66 , C07D233/72 , C07D233/88 , C07D235/06 , C07D235/08 , C07D249/08 , C07D249/10 , C07D249/12 , C07D249/14 , C07D271/06 , C07D271/07 , C07D295/15 , C07D333/20 , C07D333/36 , C07D401/12 , C07D471/04 , C07K5/072 , C07C273/00 , C07C275/00
CPC分类号： C07D233/64 , C07C237/22 , C07C237/42 , C07C255/60 , C07C257/12 , C07C257/14 , C07C257/18 , C07C259/10 , C07C259/18 , C07C261/04 , C07C275/40 , C07C279/14 , C07C279/18 , C07C279/36 , C07C307/02 , C07C307/10 , C07C311/08 , C07C311/19 , C07C311/39 , C07C311/42 , C07D209/16 , C07D209/42 , C07D209/44 , C07D213/38 , C07D215/38 , C07D223/20 , C07D233/24 , C07D233/48 , C07D233/72 , C07D233/88 , C07D235/06 , C07D249/12 , C07D249/14 , C07D271/07 , C07D295/15 , C07D333/20 , C07D471/04 , C07K5/06095 , A61K38/00 , C07C2101/08 , C07C2101/14 , C07C2103/18 , C07C2103/74
摘要： Amino acid derivatives, suitable for the treatment of obesity. The following compound is exemplary of the class: (R,S)-N.sup.2 -(diphenylacetyl)-N-�(4-hydroxyphenyl)methyl!-N.sup.5 -(1H-imidazol-2-yl)-ornithinamide.
摘要翻译：氨基酸衍生物，适用于治疗肥胖症。以下化合物是以下类别的示例：（R，S）-N 2 - （二苯基乙酰基）-N - [（4-羟基苯基）甲基] -N 5 - （1H-咪唑-2-基） - 甲硅烷基酰胺。

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