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1. 发明专利

JP2013162991A Seating apparatus 有权
标题翻译：摄影装置
公开(公告)号：JP2013162991A
公开(公告)日：2013-08-22
申请号：JP2012028976
申请日：2012-02-13
申请人： Jun Murakami , 潤村上
发明人： MURAKAMI JUN
IPC分类号： A47C7/48 , A47C7/46
摘要： PROBLEM TO BE SOLVED: To provide a seating apparatus that is adaptable to both a physically-healthy person and a physically-disabled person, and can easily maintain the posture of the head of a human body for a long period of time such that the head exactly faces to the front side so that a user can look straight naturally.SOLUTION: A seating apparatus includes a sitting part 3 supported by a frame 2, and upper support poles 8 supported by the frame 2 on the back side of the sitting part 3. The upper support poles 8 are provided with right and left rotating shafts 10 with a horizontal direction as an axial direction, and a curved back rest 4 held between the right and left rotating shafts 10, and pivotally supported for free rotation and inclination. The curved back rest 4 is provided in the curved inner surface thereof with a contact surface 6 for supporting a human body. The central portion 14 of the curved inner surface of the contact surface 6 has the most proximate position point at a position within 2 cm in radius from a support point axis connecting the right and left rotating shafts 10. In addition, the height of the upper end of the central portion of the contact surface 6 is 4 to 8 cm higher than the height of the support point axis when the curved inner surface of the contact surface is at an upright position.
摘要翻译：要解决的问题：提供一种适用于身体健康的人和身体残障者的座位装置，并且可以容易地长时间地维持人体头部的姿势，使得头部准确地面向前侧，使得用户可以自然地直视。解决方案：座椅装置包括由框架2支撑的坐立部分3和由坐在部分3的后侧上的框架2支撑的上支撑杆8 上支撑杆8设置有作为轴向方向的水平方向的左右旋转轴10和保持在左右旋转轴10之间的弯曲后支架4，并且可枢转地支撑以自由旋转和倾斜。弯曲的靠背4在其弯曲的内表面中设置有用于支撑人体的接触表面6。接触表面6的弯曲内表面的中心部分14在连接右旋转轴10和右旋转轴10的支撑点轴线的半径为2cm以内的位置处具有最接近的位置点。此外，上部当接触表面的弯曲内表面处于直立位置时，接触表面6的中心部分的端部比支撑点轴线的高度高4至8厘米。

2. 发明授权

US07605158B2 Carbamoyl-type benzofuran derivatives 失效
标题翻译：氨基甲酰型苯并呋喃衍生物
公开(公告)号：US07605158B2
公开(公告)日：2009-10-20
申请号：US10571904
申请日：2004-09-24
申请人： Takayuki Kawaguchi , Hidenori Akatsuka , Masamichi Morimoto , Tatsuya Watanabe , Toru Iijima , Jun Murakami
发明人： Takayuki Kawaguchi , Hidenori Akatsuka , Masamichi Morimoto , Tatsuya Watanabe , Toru Iijima , Jun Murakami
IPC分类号： A61K31/5355 , A61K31/443 , C07D413/04 , C07D401/12 , C07D307/85
CPC分类号： C07D405/12 , C07D405/14
摘要： The present invention provides a carbamoyl-type benzofuran derivative of the formula [1]: wherein Ring Z is a group of the formula: etc.; A is a single bond, and the like; Y is a cycloalkanediyl group, etc.; R4 and R5 are the same or different and each is an optionally substituted lower alkyl group, etc.; R1 is a halogen atom, etc.; Ring B of the formula: is an optionally substituted benzene ring; and R3 is a hydrogen atom. etc., or a pharmaceutically acceptable salt thereof, which is useful as an FXa inhibitor.
摘要翻译：本发明提供式[1]的氨基甲酰基型苯并呋喃衍生物：其中环Z是下式的基团：等等; A是单键等; Y是环烷二基等; R4和R5相同或不同，各自为任选取代的低级烷基等; R1是卤素原子等; 下式的环B是任选取代的苯环; R3为氢原子。等等，或其药学上可接受的盐，其可用作FXa抑制剂。

3. 发明申请

US20080302662A1 Method And Apparatus Of Concentration And Purification Of Nucleic Acid 审中-公开
标题翻译：核酸浓缩和纯化的方法和装置
公开(公告)号：US20080302662A1
公开(公告)日：2008-12-11
申请号：US12182001
申请日：2008-07-29
申请人： Mitsuharu HIRAI , Jun MURAKAMI , Satoshi HASHIGUCHI , Ken INOSE
发明人： Mitsuharu HIRAI , Jun MURAKAMI , Satoshi HASHIGUCHI , Ken INOSE
IPC分类号： C07K1/26
CPC分类号： C12N15/1017 , B01D61/425 , B01D61/46 , C07H21/00 , C12N15/101 , G01N27/44747
摘要： In a method for concentration and purification method of nucleic acids using electrophoresis, cationic surfactant is added to a sample containing nucleic acids so as to adjust electric charge of impurities in the sample, and then the sample is placed in an electric field for electrophoresis so as to concentrate and purify the nucleic acids. The cationic surfactant (4) adsorbs substance other than the nucleic acids so as to adjust the electric charge of the substance, and the adsorption of the cationic surfactant (4) is adjusted by the added amount of nonionic surfactant (3). Alternatively, nucleic acids are contacted with a separation medium (108), and then recovered by a filter (104) whose cross sectional area is decreased in the direction of migration.
摘要翻译：在使用电泳的核酸的浓缩和纯化方法的方法中，将阳离子表面活性剂加入到含有核酸的样品中，以调节样品中杂质的电荷，然后将样品置于电场中进行电泳，以便浓缩和纯化核酸。阳离子表面活性剂（4）吸附核酸以外的物质，以调节物质的电荷，并通过非离子表面活性剂（3）的添加量调节阳离子表面活性剂（4）的吸附。或者，核酸与分离介质（108）接触，然后通过其横截面积沿迁移方向减小的过滤器（104）回收。

4. 发明申请

US20060094724A1 Fused furan compound 失效
标题翻译：稠化呋喃化合物
公开(公告)号：US20060094724A1
公开(公告)日：2006-05-04
申请号：US10540878
申请日：2004-01-08
申请人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Tatsuya Watanabe , Jun Murakami , Takashi Mitsui
发明人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Tatsuya Watanabe , Jun Murakami , Takashi Mitsui
IPC分类号： A61K31/498 , A61K31/4741 , C07D491/02
CPC分类号： C07D491/04 , C07D213/75
摘要： The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.
摘要翻译：本发明提供式（I）的缩合呋喃化合物：其中环X为苯，吡啶等; Y是任选取代的氨基，任选取代的环烷基，任选取代的芳基，任选取代的饱和杂环基，任选取代的不饱和杂环基; A是单键，低级亚烷基，低级亚烯基，低级亚烯基或氧原子; R 3是氢等; 和R 4是氢等，或其药学上可接受的盐，其可用作药物，特别是作为活化凝血因子X抑制剂。

5. 发明申请

US20150069488A1 NONVOLATILE SEMICONDUCTOR MEMORY DEVICE 审中-公开
标题翻译：非易失性半导体存储器件
公开(公告)号：US20150069488A1
公开(公告)日：2015-03-12
申请号：US14187786
申请日：2014-02-24
申请人： Hisakazu MATSUMORI , Jun MURAKAMI
发明人： Hisakazu MATSUMORI , Jun MURAKAMI
IPC分类号： H01L21/28 , H01L29/788 , H01L29/66 , H01L29/40 , H01L27/115
CPC分类号： H01L29/66825 , H01L27/11529
摘要： According to one embodiment, a memory cell transistor is obtained by forming a first gate insulating film, a first conductive film of a first conductivity type, a first inter-electrode insulating film, and a second conductive film of the first conductivity type, in this order, and a peripheral transistor which is obtained by forming a second gate insulating film, a third conductive film of the second conductivity type opposite to the first conductivity type, the inter-electrode insulating film, a fourth conductive film in which the first conductivity type dopant is doped, a barrier film, and a fifth conductive film in which the second conductivity type dopant is doped, in which in the peripheral transistor, an opening is formed on the barrier film, the fourth conductive film, and the inter-electrode insulating film, and the fifth conductive film is formed so as to come in contact with the third conductive film through the opening.
摘要翻译：根据一个实施例，通过形成第一导电类型的第一栅极绝缘膜，第一导电类型的第一导电膜，第一电极间绝缘膜和第二导电类型的第二导电膜来获得存储单元晶体管，在该通过形成第二栅极绝缘膜，与第一导电类型相反的第二导电类型的第三导电膜，电极间绝缘膜和第四导电类型的第四导电膜获得的外围晶体管，掺杂掺杂物，阻挡膜和第五导电膜，其中掺杂有第二导电类型掺杂剂，其中在外围晶体管中，在阻挡膜，第四导电膜和电极间绝缘体上形成开口并且第五导电膜形成为通过开口与第三导电膜接触。

6. 发明授权

US07514449B2 Fused furan compound 失效
标题翻译：稠化呋喃化合物
公开(公告)号：US07514449B2
公开(公告)日：2009-04-07
申请号：US10540878
申请日：2004-01-08
申请人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Tatsuya Watanabe , Jun Murakami , Takashi Mitsui
发明人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Tatsuya Watanabe , Jun Murakami , Takashi Mitsui
IPC分类号： A61K31/444 , C07D491/048
CPC分类号： C07D491/04 , C07D213/75
摘要： The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.
摘要翻译：本发明提供式（I）的缩合呋喃化合物：其中环X为苯，吡啶等; Y是任选取代的氨基，任选取代的环烷基，任选取代的芳基，任选取代的饱和杂环基，任选取代的不饱和杂环基; A是单键，低级亚烷基，低级亚烯基，低级亚烯基或氧原子; R3是氢等; 和R4为氢等，或其药学上可接受的盐，其可用作药物，特别是活性凝血因子X抑制剂。

7. 发明申请

US20050282808A1 Benzofuran derivative 失效
标题翻译：苯并呋喃衍生物
公开(公告)号：US20050282808A1
公开(公告)日：2005-12-22
申请号：US10508512
申请日：2003-03-27
申请人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Yasunori Tsuboi , Takashi Mitsui , Jun Murakami
发明人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Yasunori Tsuboi , Takashi Mitsui , Jun Murakami
IPC分类号： A61P7/02 , C07D307/85 , C07D405/04 , C07D405/12 , C07D405/14 , A61K31/551 , A61K31/343 , A61K31/443 , A61K31/4545 , A61K31/496 , A61K31/506 , A61K31/5377
CPC分类号： C07D413/14 , C07D307/85 , C07D405/12 , C07D405/14 , C07D417/14
摘要： The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: —N═ or —CH═; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.
摘要翻译：本发明提供式[1]的苯并呋喃衍生物：其中x是下式的基团：-N-或-CH-; Y是任选取代的氨基，任选取代的环烷基或任选取代的饱和杂环基; A是单键，在链的末端或其末端具有双键的碳链或氧原子; R 1是氢原子或卤素原子; 环B是任选取代的苯环; R 3是氢原子或其药学上可接受的盐，其可用作药物，特别是作为活化凝血因子X抑制剂。

8. 发明授权

US06248743B1 Butadiene derivatives and process for preparing thereof 失效
标题翻译：丁二烯衍生物及其制备方法
公开(公告)号：US06248743B1
公开(公告)日：2001-06-19
申请号：US09143358
申请日：1998-08-28
申请人： Hiroshi Ohmizu , Akio Ohtani , Tsuyoshi Ohgiku , Hiroshi Sai , Jun Murakami
发明人： Hiroshi Ohmizu , Akio Ohtani , Tsuyoshi Ohgiku , Hiroshi Sai , Jun Murakami
IPC分类号： A61K31495
CPC分类号： C07D207/02 , C07C69/734 , C07C235/34 , C07C2601/08 , C07D211/58 , C07D213/40 , C07D213/55 , C07D213/56 , C07D213/75 , C07D213/89 , C07D231/12 , C07D231/38 , C07D231/40 , C07D233/56 , C07D239/42 , C07D249/08 , C07D261/14 , C07D317/60 , C07D401/06 , C07D405/12
摘要： A novel butadiene derivative of the formula: wherein Ring A is heterocycle, or benzene being optionally substituted by lower alkyl, alkoxy, nitro, hydroxy, substituted or unsubstituted amino or halogen, Ring B is heterocycle, or benzene being optionally substituted by lower alkoxy, lower alkylenedioxy or di-lower alkylamino, R1 and R2 are each H or lower alkyl, one of —COR32 and —COR42 is carboxyl, and the other is carboxyl being optionally esterified, or the corresponding amide or pyrrolidine derivatives, or a pharmaceutically acceptable salt thereof. Said compounds show excellent PAI-1 inhibitory activity and are useful in the prophylaxis or treatment of various thromboses such as myocardial infarction, intra-atrial thrombus in atrial fibrillation, cerebral infarction, angina pectoris, stroke, pulmonary infarction, deep venous thrombus (DVT), disseminated intravascular coagulation syndrome (DIC), diabetic complications, restenosis after percutaneous transluminal coronary angioplasty (PTCA), etc.
摘要翻译：一种下式的新型丁二烯衍生物：其中环A是杂环，或任选被低级烷基，烷氧基，硝基，羟基，取代或未取代的氨基或卤素取代的苯，环B是杂环，或任选被低级烷氧基取代的苯，低级亚烷基二氧基或二低级烷基氨基，R 1和R 2各自为H或低级烷基，-COR 32和-COR 42中的一个为羧基，另一个为任选被酯化的羧基，或相应的酰胺或吡咯烷衍生物或其药学上可接受的盐其中。所述化合物显示优异的PAI-1抑制活性，可用于预防或治疗心肌梗死，心房颤动，脑梗死，心绞痛，中风，肺梗死，深静脉血栓（DVT）等心血管栓塞，，弥漫性血管内凝血综合征（DIC），糖尿病并发症，经皮腔内冠状动脉成形术（PTCA）后再狭窄等。

9. 发明申请

US20090156803A1 Condensed furan compounds 失效
标题翻译：稠化呋喃化合物
公开(公告)号：US20090156803A1
公开(公告)日：2009-06-18
申请号：US12320583
申请日：2009-01-29
申请人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Tatsuya Watanabe , Jun Murakami , Takashi Mitsui
发明人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Tatsuya Watanabe , Jun Murakami , Takashi Mitsui
IPC分类号： C07D491/048
CPC分类号： C07D491/04 , C07D213/75
摘要： The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.
摘要翻译：本发明提供式（I）的缩合呋喃化合物：其中环X为苯，吡啶等; Y是任选取代的氨基，任选取代的环烷基，任选取代的芳基，任选取代的饱和杂环基，任选取代的不饱和杂环基; A是单键，低级亚烷基，低级亚烯基，低级亚烯基或氧原子; R3是氢等; 和R4为氢等，或其药学上可接受的盐，其可用作药物，特别是活性凝血因子X抑制剂。

10. 发明授权

US07531537B2 Benzofuran derivative 失效
标题翻译：苯并呋喃衍生物
公开(公告)号：US07531537B2
公开(公告)日：2009-05-12
申请号：US10508512
申请日：2003-03-27
申请人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Yasunori Tsuboi , Takashi Mitsui , Jun Murakami
发明人： Takayuki Kawaguchi , Hidenori Akatsuka , Toru Iijima , Yasunori Tsuboi , Takashi Mitsui , Jun Murakami
IPC分类号： A61K31/5377 , A61K31/443 , C07D413/14 , C07D405/12
CPC分类号： C07D413/14 , C07D307/85 , C07D405/12 , C07D405/14 , C07D417/14
摘要： The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: —N═ or —CH═; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.
摘要翻译：本发明提供式[1]的苯并呋喃衍生物：其中x是下式的基团：-N-或-CH-; Y是任选取代的氨基，任选取代的环烷基或任选取代的饱和杂环基; A是单键，在链的末端或其末端具有双键的碳链或氧原子; R1是氢原子或卤素原子; 环B是任选取代的苯环; 并且R3是氢原子或其药学上可接受的盐，其可用作药物，特别是作为活化凝血因子X抑制剂。

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