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1. 发明申请

US20100003332A1 Process For Preparing Powder Comprising Nanoparticles of Sparingly Soluble Drug 审中-公开
标题翻译：用于制备包含可溶性药物纳米颗粒的粉末的方法
公开(公告)号：US20100003332A1
公开(公告)日：2010-01-07
申请号：US12375232
申请日：2007-07-26
申请人： Joon Ho Bae , Jong Hwi Lee , Hyeok Lee , Jung Ju Kim
发明人： Joon Ho Bae , Jong Hwi Lee , Hyeok Lee , Jung Ju Kim
IPC分类号： A61K9/14 , A61K31/19 , A61K31/4353 , A61K31/47 , A61K31/216 , A61K31/496 , A61P43/00
CPC分类号： A61K9/5123 , A61K9/0019 , A61K9/0095 , A61K9/145 , A61K9/146 , A61K9/5161 , A61K9/5192
摘要： A powder comprising nanoparticles of a sparingly water-soluble drug prepared in accordance with the present invention exhibits enhanced bioavailability without generating adverse side effects caused by impurities, while the nano-particle size of the drug remains unchanged when administered. Accordingly, the powder can be useful for the development of a formulation of a sparingly water-soluble drug for oral and parenteral administration.
摘要翻译：包含根据本发明制备的微水溶性药物的纳米颗粒的粉末表现出增强的生物利用度，而不产生由杂质引起的不良副作用，而药物的纳米粒度在施用时保持不变。因此，粉末可用于开发用于口服和肠胃外给药的微水溶性药物的制剂。

2. 发明申请

US20110212169A1 METHOD FOR PRODUCING POWDER CONTAINING NANOPARTICULATED SPARINGLY SOLUBLE DRUG, POWDER PRODUCED THEREBY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME (As Amended) 审中-公开
标题翻译：生产含有纳米颗粒可溶性药物的粉末的方法，生产的粉末和含有它的药物组合物（如修改）
公开(公告)号：US20110212169A1
公开(公告)日：2011-09-01
申请号：US13127957
申请日：2009-11-10
申请人： Joon-Ho Bae , Hyeok Lee , Deok-Ki Hong , Jong-Hwi Lee
发明人： Joon-Ho Bae , Hyeok Lee , Deok-Ki Hong , Jong-Hwi Lee
IPC分类号： A61K9/14 , A61K9/48 , A61K9/20 , A61K31/496 , A61K31/439 , A61K31/216 , A61K31/192 , A61P17/00 , A61P37/06 , A61P1/00 , A61P31/10 , A61P3/06 , B29B9/12
CPC分类号： A61K9/146 , A61K9/1694 , A61K9/19
摘要： Disclosed are a method for preparing a powder containing a nanoparticulated sparingly soluble drug, a powder prepared thereby, and a pharmaceutical composition containing the same. The disclosed method includes: providing a uniformly dispersed solution of a sparingly soluble drug which is formed into nanoparticles in the presence of a surface stabilizer; mixing the uniformly dispersed solution with a water-soluble dispersant solution; and drying the mixed solution to obtain the powder.When the powder containing the nanoparticulated sparingly soluble drug obtained by the disclosed method is redispersed in an aqueous solution, the sparingly soluble drugretains a particle size in the nano scale while the solubility and the dissolution rate of the drug are increased, thereby providing enhanced bioavailability. Consequently, the present disclosure can be useful in the development of preparations of a sparingly soluble drug for oral or parenteral administration.
摘要翻译：公开了一种制备含有纳米颗粒的微溶药物的粉末的方法，由此制备的粉末和含有该粉末的药物组合物。所公开的方法包括：提供均匀分散的在表面稳定剂存在下形成纳米颗粒的微溶药物的溶液; 将均匀分散的溶液与水溶性分散剂溶液混合; 并干燥混合溶液得到粉末。当将通过所公开的方法获得的含有纳米颗粒的微溶药物的粉末再分散在水溶液中时，微溶药物保持纳米尺度的粒度，同时药物的溶解度和溶解速率增加，从而提供增强的生物利用度。因此，本公开内容可用于开发用于口服或肠胃外给药的微溶药物的制剂。

3. 发明申请

US20090137684A1 SUSTAINED-RELEASE PREPARATIONS AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：可持续发行的制备方法及其生产方法
公开(公告)号：US20090137684A1
公开(公告)日：2009-05-28
申请号：US12358426
申请日：2009-01-23
申请人： Jin Woo PARK , Joon Ho Bae , Jung Ju Kim
发明人： Jin Woo PARK , Joon Ho Bae , Jung Ju Kim
IPC分类号： A61K31/135
CPC分类号： A61K9/2077 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K31/00 , A61K31/485
摘要： The present invention relates to sustained-release preparations prepared by double granulation and methods for producing the same. The sustained-release preparations according to the present invention enables maintenance of effective blood concentration of drug for many hours via sustained release of the drug over 12 hours or more, and further its production is easy owing to convenience of process.
摘要翻译：本发明涉及通过双重造粒制备的缓释制剂及其制备方法。根据本发明的持续释放制剂能够通过药物持续释放12小时或更长时间维持药物的有效血药浓度许多小时，并且由于方法的便利，其进一步的生产容易。

4. 发明申请

US20070208080A1 A COMPOSITION CONTAINING A THIOUREA DERIVATIVE FOR PREVENTING OR TREATING PRURITIC OR IRRITANT SKIN DISEASES 审中-公开
标题翻译：含有THIURURA衍生物的组合物，用于预防或治疗原始或刺激性皮肤疾病
公开(公告)号：US20070208080A1
公开(公告)日：2007-09-06
申请号：US11573740
申请日：2005-08-19
申请人： Hyun Ju Koh , Jin Kyu Choi , Yeon Su Jeong , Kyung Min Lim , Joo-Hyun Moh , Joon Ho Bae , Dae Kwon Kim , Kwang Mi Kim , Chang Hoon Lee , Yung Hyup Joo , Song Seok Shin , Young-Ho Park , Young Chul Sim
发明人： Hyun Ju Koh , Jin Kyu Choi , Yeon Su Jeong , Kyung Min Lim , Joo-Hyun Moh , Joon Ho Bae , Dae Kwon Kim , Kwang Mi Kim , Chang Hoon Lee , Yung Hyup Joo , Song Seok Shin , Young-Ho Park , Young Chul Sim
IPC分类号： A61K31/265 , A61K31/17
CPC分类号： A61K31/64
摘要： Disclosed herein is a composition for preventing or treating pruritic or irritant skin diseases which comprises, as a vanilloid receptor antagonist, a thiourea derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, together with a pharmaceutically acceptable carrier.
摘要翻译：本文公开了一种用于预防或治疗瘙痒或刺激性皮肤病的组合物，其包含作为香草素受体拮抗剂的硫脲衍生物，其药学上可接受的盐，其水合物或其溶剂合物，以及药学上可接受的载体。

5. 发明申请

US20110235241A1 Flexible supercapacitor, method of manufacturing the same, and device including the flexible supercapacitor 有权
标题翻译：柔性超级电容器及其制造方法，以及包括柔性超级电容器的装置
公开(公告)号：US20110235241A1
公开(公告)日：2011-09-29
申请号：US13064425
申请日：2011-03-24
申请人： Young-jun Park , Jong-min Kim , Zhong-Iin Wang , Joon-ho Bae
发明人： Young-jun Park , Jong-min Kim , Zhong-Iin Wang , Joon-ho Bae
IPC分类号： H01G9/004 , H01G9/00
CPC分类号： H01G9/02 , H01G11/26 , H01G11/30 , H01G11/36 , H01G11/86 , Y02E60/13 , Y10T29/417
摘要： A flexible supercapacitor, a method of manufacturing the same, and a device including the same are provided, the flexible supercapacitor includes a first flexible electrode assembly, a second flexible electrode assembly corresponding to the first flexible electrode assembly, a separator for preventing contact between the first flexible electrode assembly and the second flexible electrode assembly, and an electrolyte between the first flexible electrode assembly and the second flexible electrode assembly. The flexible supercapacitor may include a tube including the first flexible electrode assembly, the second flexible electrode assembly, the separator, and the electrolyte.
摘要翻译：提供了柔性超级电容器及其制造方法以及包括该柔性超级电容器的装置，柔性超级电容器包括第一柔性电极组件，对应于第一柔性电极组件的第二柔性电极组件，用于防止第一柔性电极组件和第二柔性电极组件，以及在第一柔性电极组件和第二柔性电极组件之间的电解质。柔性超级电容器可以包括包括第一柔性电极组件，第二柔性电极组件，分离器和电解质的管。

6. 发明申请

US20080234383A1 Novel Compounds, Isomer Thereof, or Pharmaceutically Acceptable Salts Thereof as Vanilloid Receptor Antagonist; and Pharmaceutical Compositions Containing the Same 有权
标题翻译：新型化合物，异构体或其药学上可接受的盐作为香草素受体拮抗剂; 和含有它的药物组合物
公开(公告)号：US20080234383A1
公开(公告)日：2008-09-25
申请号：US11909144
申请日：2006-03-17
申请人： Young-Ger Suh , Hee-Doo Kim , Hyeung-Geun Park , Uh Taek Oh , Yong-Sil Lee , Seol Rin Park , Chong Hyon Ryu , Young-Ho Park , Song Seok Shin , Sun-Young Kim , Jin Kwan Kim , Yeon Su Jeong , Ki-Wha Lee , Jin Kyu Choi , Kyung Min Lim , Hyun Ju Koh , Joo Hyun Moh , Sung-II Kim , Joon Ho Bae
发明人： Young-Ger Suh , Hee-Doo Kim , Hyeung-Geun Park , Uh Taek Oh , Yong-Sil Lee , Seol Rin Park , Chong Hyon Ryu , Young-Ho Park , Song Seok Shin , Sun-Young Kim , Jin Kwan Kim , Yeon Su Jeong , Ki-Wha Lee , Jin Kyu Choi , Kyung Min Lim , Hyun Ju Koh , Joo Hyun Moh , Sung-II Kim , Joon Ho Bae
IPC分类号： A61K31/17 , C07C311/13 , C07C275/24 , A61P25/02 , A61K31/18
CPC分类号： C07C275/24 , C07C311/08 , C07C311/11 , C07C323/62 , C07D211/46 , C07D295/088 , C07D295/155 , C07D309/12 , C07F7/081
摘要： This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.
摘要翻译：本发明涉及新化合物，其异构体或其药学上可接受的盐作为香草素受体（Vanilloid Receotor 1; VR1; TRPV1）拮抗剂; 和含有该组合物的药物组合物。本发明提供了用于预防或治疗疼痛，偏头痛，关节痛，神经痛，神经病，神经损伤，皮肤病，尿膀胱过敏症，肠易激综合征，粪便紧急性，呼吸障碍，皮肤刺激，眼睛或粘膜，胃十二指肠溃疡，炎症性疾病，耳疾病和心脏病。

7. 发明申请

US20130162192A1 APPARATUS FOR GENERATING AND STORING ELECTRIC ENERGY 有权
标题翻译：用于生产和存储电能的装置
公开(公告)号：US20130162192A1
公开(公告)日：2013-06-27
申请号：US13537924
申请日：2012-06-29
申请人： Young-jun PARK , Jong-min KIM , Joon-ho BAE , Zhong-lin WANG
发明人： Young-jun PARK , Jong-min KIM , Joon-ho BAE , Zhong-lin WANG
IPC分类号： H02J7/00 , B82Y99/00
CPC分类号： H02J7/32 , B82Y30/00 , H01S3/06716 , H02J7/345 , H02J7/35
摘要： An apparatus for generating and storing electric energy, the apparatus including a fiber, an electric energy generation unit disposed on the fiber, and an electric energy storage unit disposed on the fiber.
摘要翻译：一种用于产生和存储电能的装置，所述装置包括光纤，设置在光纤上的电能产生单元和设置在光纤上的电能存储单元。

8. 发明申请

US20110217371A1 CONTROLLED-RELEASE MICROPARTICLES AND METHOD OF PREPARING SAME 审中-公开
标题翻译：控制释放微生物及其制备方法
公开(公告)号：US20110217371A1
公开(公告)日：2011-09-08
申请号：US13127965
申请日：2009-11-10
申请人： Kwang-Hyun Shin , Jaekwan Kim , Jai-ll Jun , Deok-Ki Hong , Joon-Ho Bae
发明人： Kwang-Hyun Shin , Jaekwan Kim , Jai-ll Jun , Deok-Ki Hong , Joon-Ho Bae
IPC分类号： A61K9/00 , A61K9/24 , A61K9/52 , A61K31/18 , A61P3/10 , A61P11/08 , A61P11/14 , A61P9/06 , A61P23/02 , A61P25/08 , A61P1/04 , A61P25/00 , A61P3/06 , A61P11/06 , A61P13/08 , A61P25/24 , A61P17/02 , A61P9/12 , A61P9/04
CPC分类号： A61K9/5047 , A61K9/5026 , A61K9/5042
摘要： Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a controlled-release stratum on the matrix. The disclosed controlled-release microparticle not only allows effective dual release control of a drug but can also exhibit outstanding dissolution characteristics even when a small amount of coating substance is used.
摘要翻译：公开了一种控释微粒：包括含有药理活性成分的基质; 以及包含在基质上形成控释层的物质的控释层。所公开的控释微粒不仅允许药物的有效双重释放控制，而且即使使用少量的包衣物质也可以表现出突出的溶解特性。

9. 发明授权

US07804468B2 Data driver system and method, for use with a display device, having improved performance characteristics 有权
标题翻译：数据驱动器系统和方法，用于显示设备，具有改进的性能特征
公开(公告)号：US07804468B2
公开(公告)日：2010-09-28
申请号：US11491270
申请日：2006-07-21
申请人： Yong Sung Park , Oh Kyong Kwon , Han Jin Bae , Joon Ho Bae , Byong Deok Choi
发明人： Yong Sung Park , Oh Kyong Kwon , Han Jin Bae , Joon Ho Bae , Byong Deok Choi
IPC分类号： G09G3/30
CPC分类号： G09G3/3283 , G09G2310/027
摘要： A data driver and a method of driving the same. The data driver includes a shift register for generating sampling signals; sampling latches for sampling digital data applied to output channels, respectively, in accordance with the sampling signals; holding latch units for receiving the sampled digital data of the channels from the sampling latches to hold the digital data for a first period; first digital-to-analog converters for receiving the held digital data of the channels from the holding latch units to generate currents corresponding to the digital data; a second digital-to-analog converter commonly connected to the channels and the first digital-to-analog converters to receive the digital data provided from the holding latch units for a second period and to generate correction currents for the data currents; and output stages for sampling, correcting, and driving final currents using the data currents and the correction currents.
摘要翻译：数据驱动器及其驱动方法。数据驱动器包括用于产生采样信号的移位寄存器; 采样锁存器，分别根据采样信号对应用于输出通道的数字数据采样; 保持锁存单元，用于从采样锁存器接收采样的信道数字数据，以保持数字数据第一周期; 第一数模转换器，用于从保持锁存单元接收保持的信道数字数据，以产生对应于数字数据的电流; 通常连接到通道的第二数模转换器和第一数模转换器，用于接收从保持锁存单元提供的第二周期的数字数据并产生数据电流的校正电流; 以及使用数据电流和校正电流对最终电流进行采样，校正和驱动的输出级。

10. 发明授权

US09607771B2 Flexible supercapacitor, method of manufacturing the same, and device including the flexible supercapacitor 有权
公开(公告)号：US09607771B2
公开(公告)日：2017-03-28
申请号：US13064425
申请日：2011-03-24
申请人： Young-jun Park , Jong-min Kim , Zhong-lin Wang , Joon-ho Bae
发明人： Young-jun Park , Jong-min Kim , Zhong-lin Wang , Joon-ho Bae
IPC分类号： H01G9/00 , H01L41/00 , H02N2/00 , H01G9/15 , H01G9/02 , H01G11/36 , H01G11/86 , H01G11/26 , H01G11/30
CPC分类号： H01G9/02 , H01G11/26 , H01G11/30 , H01G11/36 , H01G11/86 , Y02E60/13 , Y10T29/417
摘要： A flexible supercapacitor, a method of manufacturing the same, and a device including the same are provided, the flexible supercapacitor includes a first flexible electrode assembly, a second flexible electrode assembly corresponding to the first flexible electrode assembly, a separator for preventing contact between the first flexible electrode assembly and the second flexible electrode assembly, and an electrolyte between the first flexible electrode assembly and the second flexible electrode assembly. The flexible supercapacitor may include a tube including the first flexible electrode assembly, the second flexible electrode assembly, the separator, and the electrolyte.

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