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1. 外观设计

USD873449S1 Headlight cover 有权
公开(公告)号：USD873449S1
公开(公告)日：2020-01-21
申请号：US29565701
申请日：2016-05-24
申请人： Jonathan Mill
设计人： Jonathan Mill
摘要： FIG. 1 is a perspective view showing the front and left side of a headlight cover showing my new design residing on a vehicle which is shown in broken lines and forms no part of the claimed design.
FIG. 2 is a perspective view showing the front and left side of the headlight cover showing a first embodiment of my new design.
FIG. 3 is a perspective view showing the rear and left side of the headlight cover showing the first embodiment of my new design.
FIG. 4 is a front view showing the first embodiment of my new design.
FIG. 5 is a side view showing the first embodiment of my new design.
FIG. 6 is a rear view showing the first embodiment of my new design.
FIG. 7 is a top view showing the first embodiment of my new design.
FIG. 8 is a bottom view showing the first embodiment of my new design.
FIG. 9 is a perspective view showing the front and left side of the headlight cover showing a second embodiment of my new design.
FIG. 10 is a perspective view showing the rear and left side of the headlight cover showing the second embodiment of my new design.
FIG. 11 is a front view showing the second embodiment of my new design.
FIG. 12 is a side view showing the second embodiment of my new design.
FIG. 13 is a rear view showing the second embodiment of my new design.
FIG. 14 is a top view showing the second embodiment of my new design; and,
FIG. 15 is a bottom view showing the second embodiment of my new design.

2. 发明申请

US20120220475A1 DNA Methylation Changes Associated with Major Psychosis 审中-公开
标题翻译： DNA甲基化变化与主要精神病相关
公开(公告)号：US20120220475A1
公开(公告)日：2012-08-30
申请号：US13337394
申请日：2011-12-27
申请人： Arturas PETRONIS , Jonathan MILL , James FLANAGAN , Sun-Chong WANG
发明人： Arturas PETRONIS , Jonathan MILL , James FLANAGAN , Sun-Chong WANG
IPC分类号： C40B30/04 , C40B40/06
CPC分类号： C12Q1/6883 , C12Q2600/154 , C40B30/00 , C40B40/06
摘要： The present invention provides a method of identifying one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia, the method comprising a) obtaining a first group of samples comprising genomic DNA from a plurality of bipolar or schizophrenic subjects and a second group of samples comprising genomic DNA from a plurality of control subjects; b) performing DNA methylation analysis to determine methylation differences in one or more DNA regions between the first group and second group of samples, wherein a methylation difference in a DNA region is indicative of an epigenetic marker associated with bipolar disease or schizophrenia. The invention also provides one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia.
摘要翻译：本发明提供了鉴定与精神病相关疾病如双相性精神障碍或精神分裂症相关的一种或多种表观遗传标记的方法，所述方法包括：a）获得包含来自多个双相或精神分裂症受试者的基因组DNA的第一组样品，第二组样本，其包含来自多个对照受试者的基因组DNA; b）进行DNA甲基化分析以确定第一组和第二组样品之间的一个或多个DNA区域的甲基化差异，其中DNA区域中的甲基化差异指示与双相性精神障碍或精神分裂症相关的表观遗传学标记。本发明还提供与精神病相关疾病如双相性精神障碍或精神分裂症相关的一种或多种表观遗传标记。

3. 发明申请

US20100234242A1 DNA Methylation Changes Associated with Major Psychosis 审中-公开
标题翻译： DNA甲基化变化与主要精神病相关
公开(公告)号：US20100234242A1
公开(公告)日：2010-09-16
申请号：US12524114
申请日：2008-01-23
申请人： Arturas Petronis , Jonathan Mill , James Flanagan , Sun-Chong Wang
发明人： Arturas Petronis , Jonathan Mill , James Flanagan , Sun-Chong Wang
IPC分类号： C40B30/06 , C12Q1/68 , C40B40/06 , C07D239/47 , C07H21/00
CPC分类号： C12Q1/6883 , C12Q2600/154 , C40B30/00 , C40B40/06
摘要： The present invention provides a method of identifying one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia, the method comprising a) obtaining a first group of samples comprising genomic DNA from a plurality of bipolar or schizophrenic subjects and a second group of samples comprising genomic DNA from a plurality of control subjects; b) performing DNA methylation analysis to determine methylation differences in one or more DNA regions between the first group and second group of samples, wherein a methylation difference in a DNA region is indicative of an epigenetic marker associated with bipolar disease or schizophrenia. The invention also provides one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia.
摘要翻译：本发明提供了鉴定与精神病相关疾病如双相性精神障碍或精神分裂症相关的一种或多种表观遗传标记的方法，所述方法包括：a）获得包含来自多个双相或精神分裂症受试者的基因组DNA的第一组样品，第二组样本，其包含来自多个对照受试者的基因组DNA; b）进行DNA甲基化分析以确定第一组和第二组样品之间的一个或多个DNA区域的甲基化差异，其中DNA区域中的甲基化差异指示与双相性精神障碍或精神分裂症相关的表观遗传学标记。本发明还提供与精神病相关疾病如双相性精神障碍或精神分裂症相关的一种或多种表观遗传标记。

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