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1. 发明授权

US06821111B2 Lattice gate for drop gate injection molding 失效
标题翻译：格栅门浇注浇注注塑
公开(公告)号：US06821111B2
公开(公告)日：2004-11-23
申请号：US10449551
申请日：2003-05-30
申请人： Robert Henry Vogliano , Mark Russell Miller , John Richard White
发明人： Robert Henry Vogliano , Mark Russell Miller , John Richard White
IPC分类号： B29C4520
CPC分类号： B29C45/2701 , B29C45/2708 , B29K2021/00
摘要： The present invention is directed towards the hybrid combination of a drop gate injection molding system and a lattice gate. The lattice gate is located prior to the orifice of the drop gate. The lattice gate is comprised of a series of cross-direction flow channels through which the rubber flows, with mixing of the rubbers at the intersections of the flow channels. This hybrid molding system permits shorter cure times, and improved process cycle time for curing rubbers.
摘要翻译：本发明涉及液滴栅注射成型系统和格栅的混合组合。格栅门位于滴浇口的孔口之前。格栅由一系列横向流动通道组成，橡胶流过该通道，橡胶在流动通道的交点处混合。该混合成型系统允许较短的固化时间，并且改善固化橡胶的工艺循环时间。

2. 发明授权

US06645989B2 Compounds 失效
标题翻译：化合物
公开(公告)号：US06645989B2
公开(公告)日：2003-11-11
申请号：US09818491
申请日：2001-03-27
申请人： Jerry Leroy Adams , Timothy Francis Gallagher , John C. Lee , John Richard White
发明人： Jerry Leroy Adams , Timothy Francis Gallagher , John C. Lee , John Richard White
IPC分类号： A61K314439
CPC分类号： C07D401/04 , C07D403/04 , C07D409/14 , C07D413/14 , C07D495/04 , C07F9/6506 , C07F9/65583
摘要： Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
摘要翻译：新型2,4,5-三芳基咪唑化合物和用于治疗的组合物。

3. 发明授权

US06387313B1 Gate for injection molding rubber compounds 失效
标题翻译：注塑门橡胶胶
公开(公告)号：US06387313B1
公开(公告)日：2002-05-14
申请号：US09461907
申请日：1999-12-15
申请人： Ching-Chian Chang , John Richard White
发明人： Ching-Chian Chang , John Richard White
IPC分类号： B29C4500
CPC分类号： B29C45/0005 , B29C45/2701 , B29C2045/0006 , B29K2021/00
摘要： A combination rubber injection gate system (24) and method of injection molding rubber to produce desired flow patterns in the rubber is disclosed. The combination gate (24) directs rubber through a first region (26) to flow at cross angles (38, 40) through the injection gate (24), relative to the direction of flow of the rubber (22) through the injection gate (24). The rubber (22) is then directed through an adjacent region (28) to flow through the injection gate (24) at a direction parallel to the direction of flow of the rubber (22) through the entire injection gate (24). The combination gate (24) yields a highly mixed and uniform flow of rubber (22) that is particularly useful when injection molding fiber-loaded rubber where it is desired to orient the fibers in a particular direction.
摘要翻译：公开了一种组合橡胶注射门系统（24）和注射橡胶的方法以在橡胶中产生所需的流动模式。组合门24引导橡胶穿过第一区域26相对于橡胶（22）通过喷射门（22）的流动方向通过喷射浇口（24）以交叉角（38,40）流动 24）。然后，橡胶（22）被引导通过相邻区域（28），以通过整个喷射门（24）沿与橡胶（22）的流动方向平行的方向流过喷射门（24）。组合门（24）产生高度混合且均匀的橡胶流动（22），当注射成型纤维负载的橡胶时，其需要在特定方向上定向纤维时特别有用。

4. 发明授权

US06231026B1 Tire curing bladder containing lecithin and use thereof 失效
标题翻译：含有卵磷脂的轮胎硫化膀胱及其用途
公开(公告)号：US06231026B1
公开(公告)日：2001-05-15
申请号：US09379040
申请日：1999-08-23
申请人： George Philemon Patitsas , Paul Harry Sandstrom , John Richard White , Bharat Kanchanlal Kansupada
发明人： George Philemon Patitsas , Paul Harry Sandstrom , John Richard White , Bharat Kanchanlal Kansupada
IPC分类号： B29C3500
CPC分类号： B29D30/0654 , B29C33/50 , B29D2030/0655 , C08K5/103 , C08K5/521 , C08L23/22 , C08L91/00 , C08L2205/06 , C08L2666/02
摘要： The invention relates to expandable butyl rubber bladders for use in curing presses for hydrocarbon rubbers such as pneumatic tires. The bladders are a crosslinked elastomer comprising isobutylene repeat units and the bladder composition contains lecithin, particularly a modified lecithin, preferably in liquid form, dispersed within the bladder composition. The bladder composition may also contain castor oil, corn oil and/or soya-bean oil. The bladder composition may also contain at least one of graphite and polytetrafluoroethylene powder. The invention also relates to a method of curing tires by utilizing such butyl rubber bladder.
摘要翻译：本发明涉及用于固化碳氢化合物橡胶如充气轮胎的压力机的可膨胀的丁基橡胶囊。气囊是包含异丁烯重复单元的交联弹性体，并且膀胱组合物含有分散在膀胱组合物内的卵磷脂，特别是改性卵磷脂，优选液体形式。膀胱组合物还可以含有蓖麻油，玉米油和/或大豆油。膀胱组合物还可以含有石墨和聚四氟乙烯粉末中的至少一种。本发明还涉及通过利用这种丁基胶囊来固化轮胎的方法。

5. 发明授权

US06379603B1 Lattice gate for injection molding of rubber compounds 失效
标题翻译：用于橡胶化合物注塑的格栅
公开(公告)号：US06379603B1
公开(公告)日：2002-04-30
申请号：US09445522
申请日：1999-12-07
申请人： John Richard White , Robert Henry Vogliano
发明人： John Richard White , Robert Henry Vogliano
IPC分类号： B29C4500
CPC分类号： B29C45/2701 , B29K2021/00
摘要： The present invention relates to a lattice gate for directing streams of rubber into an injection molding device through a plurality of intersecting channels (78, 80) which thermally mix the streams of rubber within the gate (76) as they pass through the intersections of the flow channels permitting the injection time of the rubber into the mold cavity to be decreased while simultaneously reducing the time for curing the rubber within the mold.
摘要翻译：本发明涉及一种用于通过多个相交通道（78,80）将橡胶流引导到注射成型装置中的格栅门，当通过门（76）的交叉点允许橡胶进入模腔的注射时间的流动通道减少，同时减少在模具内固化橡胶的时间。

6. 发明授权

US06290948B1 Method of treating sepsis and ARDS using chamohine beta-10 失效
标题翻译：使用洋甘菊β-10治疗败血症和ARDS的方法
公开(公告)号：US06290948B1
公开(公告)日：2001-09-18
申请号：US08852212
申请日：1997-05-06
申请人： John Richard White , Louis Martin Pelus
发明人： John Richard White , Louis Martin Pelus
IPC分类号： A61K4505
CPC分类号： A61K38/195 , A61K31/175 , A61K31/546 , A61K31/7036 , Y10S514/885 , Y10S514/921 , A61K2300/00
摘要： The invention relates to the method of preventing and treating sepsis and ARDS using chemokine or biologically active fragment thereof, alone or in conjunction with an anti-infective agent.
摘要翻译：本发明涉及使用趋化因子或其生物活性片段单独或与抗感染剂联合预防和治疗败血症和ARDS的方法。

7. 发明授权

US06268370B1 Compounds 失效
标题翻译：化合物
公开(公告)号：US06268370B1
公开(公告)日：2001-07-31
申请号：US09270866
申请日：1999-03-16
申请人： Jerry Leroy Adams , Timothy Francis Gallagher , John C. Lee , John Richard White
发明人： Jerry Leroy Adams , Timothy Francis Gallagher , John C. Lee , John Richard White
IPC分类号： A61K31505
CPC分类号： C07D401/04 , C07D403/04 , C07D409/14 , C07D413/14 , C07D495/04 , C07F9/6506 , C07F9/65583
摘要： Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
摘要翻译：新型2,4,5-三芳基咪唑化合物和用于治疗的组合物

8. 发明申请

US20120095193A1 POLYPEPTIDES AND METHOD OF TREATMENT 审中-公开
标题翻译：多肽和治疗方法
公开(公告)号：US20120095193A1
公开(公告)日：2012-04-19
申请号：US13379748
申请日：2010-07-01
申请人： Michael Neil Burden , Paul Andrew Hamblin , Jonathan David Larkin , John Richard White
发明人： Michael Neil Burden , Paul Andrew Hamblin , Jonathan David Larkin , John Richard White
IPC分类号： C07K16/40 , C12N1/15 , C12N1/21 , C12N1/19 , C12N15/13 , C12N5/10
CPC分类号： C07K16/40 , A61K2039/505 , C07K2317/24 , C07K2317/71 , C07K2317/732 , C07K2317/76 , C07K2317/92
摘要： Provided herein are isolated antigen binding protein comprising at least one first immunoglobulin variable domain capable of binding to human ADAMTS5. Also provided are antigen binding proteins of the present invention that are monoclonal antibodies, pharmaceutical compositions comprising said antigen binding proteins and methods of treatment.
摘要翻译：本文提供了分离的抗原结合蛋白，其包含能够结合人ADAMTS5的至少一个第一免疫球蛋白可变结构域。还提供了作为单克隆抗体的本发明的抗原结合蛋白，包含所述抗原结合蛋白的药物组合物和治疗方法。

9. 发明授权

US06796786B2 Runner for injection molding 失效
公开(公告)号：US06796786B2
公开(公告)日：2004-09-28
申请号：US10638912
申请日：2003-08-11
申请人： John Richard White , Robert Henry Vogliano
发明人： John Richard White , Robert Henry Vogliano
IPC分类号： B29C4518
CPC分类号： B29C45/2701 , B01F5/0645 , B01F2215/0049 , B29K2021/00 , B29K2075/00
摘要： The present invention is directed to the structure of an inline runner for injection molding which uniformly increases the temperature of the injected compound as the compound flows from the injection port to single or multiple drop gates at the entrance to single or multiple injection mold cavities. The inline runner has two opposing series of parallel channels formed into the runner for the purpose of mixing the compound as it flows through the runner.

10. 发明授权

US06607688B1 Lattice gate for drop gate injection molding 失效
标题翻译：格栅门浇注浇注注塑
公开(公告)号：US06607688B1
公开(公告)日：2003-08-19
申请号：US09658087
申请日：2000-09-08
申请人： Robert Henry Vogliano , Mark Russell Miller , John Richard White
发明人： Robert Henry Vogliano , Mark Russell Miller , John Richard White
IPC分类号： B29C4500
CPC分类号： B29C45/2701 , B29C45/2708 , B29K2021/00
摘要： The present invention is directed towards the hybrid combination of a drop gate injection molding system and a lattice gate. The lattice gate is located prior to the orifice of the drop gate. The lattice gate is comprised of a series of cross-direction flow channels through which the rubber flows, with mixing of the rubbers at the intersections of the flow channels. This hybrid molding system permits shorter cure times, and improved process cycle time for curing rubbers.
摘要翻译：本发明涉及液滴栅注射成型系统和格栅的混合组合。格栅门位于滴浇口的孔口之前。格栅由一系列横向流动通道组成，橡胶流过该通道，橡胶在流动通道的交点处混合。该混合成型系统允许较短的固化时间，并且改善固化橡胶的工艺循环时间。

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