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1. 发明授权

US06808739B2 Drying method for selectively removing volatile components from wet coatings 失效
标题翻译：用于从湿涂层选择性去除挥发性组分的干燥方法
公开(公告)号：US06808739B2
公开(公告)日：2004-10-26
申请号：US09960132
申请日：2001-09-21
申请人： Richard G. Sitz , Peter T. Benson , Kathleen M. Cooklock , Gary L. Huelsman , Nirmal K. Jain , William Blake Kolb , John M. Sever
发明人： Richard G. Sitz , Peter T. Benson , Kathleen M. Cooklock , Gary L. Huelsman , Nirmal K. Jain , William Blake Kolb , John M. Sever
IPC分类号： B05D134
CPC分类号： A61K9/7061 , B01D5/0066 , F26B3/20 , F26B13/105 , F26B25/006
摘要： Method of selectively removing volatile components from a composition, comprising coating the composition onto a first substrate surface of a substrate, wherein the composition comprises a nonresident volatile component and a resident volatile component. The method further includes positioning at least a portion of the coated substrate between a condensing surface having a condensing surface temperature and a heating surface having a heating surface temperature that is greater than the condensing surface temperature, wherein the condensing surface is in a spaced apart, confronting relationship to the coated surface of the substrate and wherein the heated surface is in thermal contact with a second substrate surface opposite the first substrate surface. In the method, the heated surface temperature and the condensing surface temperature are such that the positioning step causes the nonresident volatile component to be selectively removed from the portion of the coated substrate. The method is suitable for forming transdermal drug delivery compositions.
摘要翻译：从组合物中选择性地除去挥发性组分的方法，包括将组合物涂覆在基材的第一基材表面上，其中所述组合物包含非驻留的挥发性组分和驻留的挥发性组分。该方法还包括将涂覆的基底的至少一部分定位在具有冷凝表面温度的冷凝表面和具有大于冷凝表面温度的加热表面温度的加热表面之间，其中冷凝表面间隔开，与衬底的涂覆表面面对的关系，并且其中加热的表面与与第一衬底表面相对的第二衬底表面热接触。在该方法中，加热的表面温度和冷凝表面温度使得定位步骤使非常规的挥发性组分从涂覆的基底的部分选择性地去除。该方法适用于形成透皮药物递送组合物。

2. 发明授权

US08608889B2 Method for handling adhesive laminate sections 有权
标题翻译：粘合层压板处理方法
公开(公告)号：US08608889B2
公开(公告)日：2013-12-17
申请号：US11916457
申请日：2006-06-08
申请人： John M. Sever , Gordon P. Knutson
发明人： John M. Sever , Gordon P. Knutson
IPC分类号： B44C1/17 , B65C9/18 , B29C65/00 , B32B37/00 , B32B38/10 , B32B38/04 , B65C9/25 , C09J5/00
CPC分类号： B32B37/025 , A61F2013/0296 , A61K9/703 , A61K9/7038 , B29C65/4825 , B29C2793/0036 , Y10T156/1064 , Y10T156/1077 , Y10T156/108 , Y10T156/1082 , Y10T156/1084 , Y10T156/1097
摘要： A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method.
摘要翻译：一种处理粘合剂层压体的方法，其中粘合剂层压体被可释放地粘附到第一纤维网上，包括多个切割或冲压部分，并且其中粘合层压板的相邻部分沿着幅材的纵向方向彼此连接一个或多个连接点。提供了与第一支撑结构相邻的第一支撑结构和第二支撑结构。第一个网络被引导到第一个支撑结构。提供第二纤维网并将其引导到第二支撑结构上，其中第二纤维网被定向成使得第二纤维网的释放表面面向第一支撑结构。来自第一纤维网的粘合剂层压体的第一部分的引导部分附接到第二纤维网的释放表面，并且第二纤维网前进，使得粘合剂层压体的第一部分从粘合剂层压体的第二部分分离，并且粘合剂层压体的第二部分的前缘以与粘合层压体的第一部分的后缘隔开的构造粘附到第二腹板。通过这种方法制备的透皮药物递送装置。

3. 发明申请

US20080202675A1 Method for Handling Adhesive Laminate Sections 有权
标题翻译：处理粘合层压板部分的方法
公开(公告)号：US20080202675A1
公开(公告)日：2008-08-28
申请号：US11916457
申请日：2006-06-08
申请人： John M. Sever , Gordon P. Knutson
发明人： John M. Sever , Gordon P. Knutson
IPC分类号： A61F13/02
CPC分类号： B32B37/025 , A61F2013/0296 , A61K9/703 , A61K9/7038 , B29C65/4825 , B29C2793/0036 , Y10T156/1064 , Y10T156/1077 , Y10T156/108 , Y10T156/1082 , Y10T156/1084 , Y10T156/1097
摘要： A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method.
摘要翻译：一种处理粘合剂层压体的方法，其中粘合剂层压体被可释放地粘附到第一纤维网上，包括多个切割或冲压部分，并且其中粘合层压板的相邻部分沿着幅材的纵向方向彼此连接一个或多个连接点。提供了与第一支撑结构相邻的第一支撑结构和第二支撑结构。第一个网络被引导到第一个支撑结构。提供第二纤维网并将其引导到第二支撑结构上，其中第二纤维网被定向成使得第二纤维网的释放表面面向第一支撑结构。来自第一纤维网的粘合剂层压体的第一部分的引导部分附接到第二纤维网的释放表面，并且第二纤维网前进，使得粘合剂层压体的第一部分从粘合剂层压体的第二部分分离，并且粘合剂层压体的第二部分的前缘以与粘合层压体的第一部分的后缘隔开的构造粘附到第二腹板。通过这种方法制备的透皮药物递送装置。

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