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    • 5. 发明申请
    • Materials containing multiple layers of vesicles
    • 含有多层囊泡的材料
    • US20080063898A1
    • 2008-03-13
    • US11981208
    • 2007-10-31
    • John LallyNicholas Kotov
    • John LallyNicholas Kotov
    • B05D7/00B32B9/00
    • G02B1/043A61K9/127
    • The present invention provides a composite material, preferably an ophthalmic device, more preferably a contact lens, which comprises a vesicle-containing coating including at least one layer of a vesicle and one layer of a polyionic material having charges opposite the charges of the vesicle. Such composite material can find use in biomedical applications, for example, a device for localized drug delivery and an in vivo analyte sensor such as glucose sensing contact lens. By lifting off the vesicle-containing coating from a substrate, a self-standing membrane (film) capable of encapsulating a wide variety of guest materials can be prepared. In addition, the invention provides methods for making vesicle-containing composite and film materials of the present invention.
    • 本发明提供一种复合材料,优选眼科装置,更优选隐形眼镜,其包括含囊泡的涂层,其包含至少一层囊泡和一层具有与囊泡的电荷相反的电荷的聚离子材料。 这种复合材料可用于生物医学应用,例如用于局部药物递送的装置和体内分析物传感器,例如葡萄糖感测隐形眼镜。 通过从基材上取出含囊泡的涂层,可以制备能够包封各种客体材料的自立膜(膜)。 另外,本发明提供了制造本发明的含囊泡复合材料和薄膜材料的方法。
    • 8. 发明授权
    • Method for applying a coating
    • 施加涂层的方法
    • US06811805B2
    • 2004-11-02
    • US10154249
    • 2002-05-22
    • Allen GilliardLynn Cook WintertonRafael Victor AndinoJohn Lally
    • Allen GilliardLynn Cook WintertonRafael Victor AndinoJohn Lally
    • A61L5103
    • B29D11/00317B29D11/00903G02B1/10
    • The invention provide a method for applying a coating to an ophthalmic lens or a mold for making the ophthalmic lens or a medical device other than ophthalmic lens. The method comprises spraying at least one layer of a coating liquid onto an ophthalmic lens using a spraying process selected from the group consisting of an air-assisted atomization and dispensing process, an ultrasonic-assisted atomization and dispensing process, a piezoelectric assisted atomization and dispensing process, an electro-mechanical jet printing process, a piezo-electric jet printing process, a piezo-electric with hydrostatic pressure jet printing process, and a thermal jet printing process. The coating can comprise a property/functionality pattern or a color image or combination of both.
    • 本发明提供了一种将涂层施加到眼用透镜或用于制造眼科镜片或除眼镜之外的医疗装置的模具的方法。 该方法包括使用选自空气辅助雾化和分配过程,超声波辅助雾化和分配过程,压电辅助雾化和分配过程的喷雾方法将至少一层涂布液体喷涂到眼科镜片上 工艺,机电喷射印刷工艺,压电喷墨印刷工艺,静压喷射印刷工艺的压电和热喷涂印刷工艺。 涂层可以包括性质/功能性图案或彩色图像或两者的组合。